Arginine conjugates of metallo-supramolecular cylinders prescribe helicity and enhance DNA junction binding and cellular activity.

L Cardo, Victoria Sadovnikova, S Phongtongpasuk, Nikolas Hodges, Michael Hannon

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

The conjugation of arginine residues at the ends of a metallo-supramolecular triple-helical cylinder enables absolute control over the helicity of the cylinder core, and boosts the DNA junction recognition by the complexes and their activity against a cancer cell line.
Original languageEnglish
Pages (from-to)6575-6577
Number of pages3
JournalChemical Communications
Volume47
Issue number23
DOIs
Publication statusPublished - 9 May 2011

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