Aquaporins and Their Regulation after Spinal Cord Injury

Research output: Contribution to journalReview article

Standard

Aquaporins and Their Regulation after Spinal Cord Injury. / Halsey, Andrea M; Conner, Alex C; Bill, Roslyn M; Logan, Ann; Ahmed, Zubair.

In: Cells, Vol. 7, No. 10, 174, 18.10.2018.

Research output: Contribution to journalReview article

Harvard

APA

Vancouver

Author

Bibtex

@article{0b226c8b82f84d92afa85564fc08f005,
title = "Aquaporins and Their Regulation after Spinal Cord Injury",
abstract = "After injury to the spinal cord, edema contributes to the underlying detrimental pathophysiological outcomes that lead to worsening of function. Several related membrane proteins called aquaporins (AQPs) regulate water movement in fluid transporting tissues including the spinal cord. Within the cord, AQP1, 4 and 9 contribute to spinal cord injury (SCI)-induced edema. AQP1, 4 and 9 are expressed in a variety of cells including astrocytes, neurons, ependymal cells, and endothelial cells. This review discusses some of the recent findings of the involvement of AQP in SCI and highlights the need for further study of these proteins to develop effective therapies to counteract the negative effects of SCI-induced edema.",
keywords = "aquaporin, edema, spinal cord injury, water channel",
author = "Halsey, {Andrea M} and Conner, {Alex C} and Bill, {Roslyn M} and Ann Logan and Zubair Ahmed",
year = "2018",
month = "10",
day = "18",
doi = "10.3390/cells7100174",
language = "English",
volume = "7",
journal = "Cells",
issn = "2073-4409",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "10",

}

RIS

TY - JOUR

T1 - Aquaporins and Their Regulation after Spinal Cord Injury

AU - Halsey, Andrea M

AU - Conner, Alex C

AU - Bill, Roslyn M

AU - Logan, Ann

AU - Ahmed, Zubair

PY - 2018/10/18

Y1 - 2018/10/18

N2 - After injury to the spinal cord, edema contributes to the underlying detrimental pathophysiological outcomes that lead to worsening of function. Several related membrane proteins called aquaporins (AQPs) regulate water movement in fluid transporting tissues including the spinal cord. Within the cord, AQP1, 4 and 9 contribute to spinal cord injury (SCI)-induced edema. AQP1, 4 and 9 are expressed in a variety of cells including astrocytes, neurons, ependymal cells, and endothelial cells. This review discusses some of the recent findings of the involvement of AQP in SCI and highlights the need for further study of these proteins to develop effective therapies to counteract the negative effects of SCI-induced edema.

AB - After injury to the spinal cord, edema contributes to the underlying detrimental pathophysiological outcomes that lead to worsening of function. Several related membrane proteins called aquaporins (AQPs) regulate water movement in fluid transporting tissues including the spinal cord. Within the cord, AQP1, 4 and 9 contribute to spinal cord injury (SCI)-induced edema. AQP1, 4 and 9 are expressed in a variety of cells including astrocytes, neurons, ependymal cells, and endothelial cells. This review discusses some of the recent findings of the involvement of AQP in SCI and highlights the need for further study of these proteins to develop effective therapies to counteract the negative effects of SCI-induced edema.

KW - aquaporin

KW - edema

KW - spinal cord injury

KW - water channel

U2 - 10.3390/cells7100174

DO - 10.3390/cells7100174

M3 - Review article

C2 - 30340399

VL - 7

JO - Cells

JF - Cells

SN - 2073-4409

IS - 10

M1 - 174

ER -