Applications of compressive sensing in spatial frequency domain imaging

Research output: Contribution to journalArticlepeer-review

Authors

  • Ben O. L. Mellors
  • Alexander Bentley
  • Abigail M. Spear
  • Christopher R. Howle
  • Hamid Dehghani

Colleges, School and Institutes

External organisations

  • Defence Science and Technology Laboratory, Porton Down, Salisbury, United Kingdom

Abstract

Significance: Spatial frequency domain imaging (SFDI) is an imaging modality that projects spatially modulated light patterns to determine optical property maps for absorption and reduced scattering of biological tissue via a pixel-by-pixel data acquisition and analysis procedure. Compressive sensing (CS) is a signal processing methodology which aims to reproduce the original signal with a reduced number of measurements, addressing the pixel-wise nature of SFDI. These methodologies have been combined for complex heterogenous data in both the image detection and data analysis stage in a compressive sensing SFDI (cs-SFDI) approach, showing reduction in both the data acquisition and overall computational time.

Aim: Application of compressive sensing in SFDI data acquisition and image reconstruction significantly improves data collection and image recovery time without loss of quantitative accuracy.

Approach: In this work, cs-SFDI has been applied to an increased heterogenic sample from the AppSFDI data set (back of the hand), highlighting the increased number of CS measurements required as compared to simple phantoms to accurately obtain optical property maps. A novel application of CS to the parameter recovery stage of image analysis has also been developed and validated.

Results: Dimensionality reduction has been demonstrated using the increased heterogenic sample at both the acquisition and at analysis stages. A data reduction of 30% for the cs-SFDI and up to 80% for the parameter recover was achieved as compared to traditional SFDI, whilst maintaining an error of <10% for the recovered optical property maps.

Conclusion: The application of data reduction through Compressive Sensing demonstrates additional capabilities for multi- and hyperspectral SFDI, providing advanced optical and physiological property maps.

Details

Original languageEnglish
Article number112904
JournalJournal of Biomedical Optics
Volume2020
Publication statusPublished - 11 Nov 2020

Keywords

  • SFDI, Compressive sensing, Data reduction