Anti-neutrophil cytoplasm-associated glomerulonephritis.

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Colleges, School and Institutes


Wegener's granulomatosis, microscopic polyangiitis, and renal limited vasculitis are associated with circulating anti-neutrophil cytoplasm antibodies and are an important cause of rapidly progressive glomerulonephritis. This review gives an account of recent advances in the understanding of the pathogenesis underlying these conditions and how these may lead to future treatments. Consideration is given to recent clinical trials in the management of anti-neutrophil cytoplasm antibodies (ANCA)-associated vasculitides.


Original languageEnglish
Pages (from-to)1224-34
Number of pages11
JournalJournal of the American Society of Nephrology
Issue number5
Publication statusPublished - 1 May 2006