Antibodies to citrullinated α-enolase peptide 1 and clinical and radiological outcomes in rheumatoid arthritis

Research output: Contribution to journalArticlepeer-review

Authors

  • Darren Plant
  • Monica Brode
  • Ronald F van Vollenhoven
  • Linda Mathsson
  • Deborah Symmons
  • Karin Lundberg
  • Johan Rönnelid
  • Patrick J Venables

Colleges, School and Institutes

Abstract

The anticyclic citrullinated peptide 2 (anti-CCP2) assay is a generic test for antibodies to citrullinated proteins, among which there is a subset of about 50% with antibodies to citrullinated enolase peptide 1 (CEP-1). The anti-CEP-1 positive subset is strongly associated with the HLA-DRB1 shared epitope and its interaction with smoking.

Details

Original languageEnglish
Pages (from-to)1095-8
Number of pages4
JournalAnnals of the Rheumatic Diseases
Volume70
Issue number6
Publication statusPublished - 2011