Anthracene-modified oligonucleotides as fluorescent DNA mismatch sensors: discrimination between various base-pair mismatches
Research output: Contribution to journal › Article › peer-review
A fluorescent anthracene-tagged DNA probe has been shown to respond to various DNA sequences by changes to its emission signal upon duplex formation. The fluorescence response for duplexes containing a single mismatch near the anthracene site has been found to be very sensitive to its composition, with the emission signal increasing for a CA mismatch and decreasing for CT and CC mismatches.
|Number of pages||5|
|Early online date||13 Apr 2011|
|Publication status||Published - 2011|
- sensor, fluorescence, anthracene, SNP, DNA