Analysis of ZAP70 expression in adult acute lymphoblastic leukaemia by real time quantitative PCR

Geothy Chakupurakal, Andrew Bell, Mike Griffiths, Farooq Wandroo, Paul Moss

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

ZAP70 gene expression is associated with poor prognosis in B-cell lymphoproliferative disorders especially chronic lymphocytic leukaemia (CLL) but its role in adult B-ALL has not been established. On diagnostic samples from 76 patients with adult ALL (65 with B-ALL and 11 with T-ALL) ZAP70 mRNA expression levels were studied by real time-quantitative PCR (RT-qPCR) analysis.
Original languageEnglish
Pages (from-to)22
JournalMolecular Cytogenetics
Volume5
Issue number1
DOIs
Publication statusPublished - 2012

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