An androgenic steroid delivery vector that imparts activity to a non-conventional platinum(II) metallo-drug

Research output: Contribution to journalArticle

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An androgenic steroid delivery vector that imparts activity to a non-conventional platinum(II) metallo-drug. / Huxley, M; Sanchez-Cano, C; Browning, MJ; Navarro-Ranninger, C; Quiroga, AG; Rodger, A; Hannon, MJ; Hannon, Michael.

In: Dalton Transactions, Vol. 39, No. 47, 01.01.2010, p. 11353-11364.

Research output: Contribution to journalArticle

Harvard

Huxley, M, Sanchez-Cano, C, Browning, MJ, Navarro-Ranninger, C, Quiroga, AG, Rodger, A, Hannon, MJ & Hannon, M 2010, 'An androgenic steroid delivery vector that imparts activity to a non-conventional platinum(II) metallo-drug', Dalton Transactions, vol. 39, no. 47, pp. 11353-11364. https://doi.org/10.1039/c0dt00838a

APA

Huxley, M., Sanchez-Cano, C., Browning, MJ., Navarro-Ranninger, C., Quiroga, AG., Rodger, A., Hannon, MJ., & Hannon, M. (2010). An androgenic steroid delivery vector that imparts activity to a non-conventional platinum(II) metallo-drug. Dalton Transactions, 39(47), 11353-11364. https://doi.org/10.1039/c0dt00838a

Vancouver

Huxley M, Sanchez-Cano C, Browning MJ, Navarro-Ranninger C, Quiroga AG, Rodger A et al. An androgenic steroid delivery vector that imparts activity to a non-conventional platinum(II) metallo-drug. Dalton Transactions. 2010 Jan 1;39(47):11353-11364. https://doi.org/10.1039/c0dt00838a

Author

Huxley, M ; Sanchez-Cano, C ; Browning, MJ ; Navarro-Ranninger, C ; Quiroga, AG ; Rodger, A ; Hannon, MJ ; Hannon, Michael. / An androgenic steroid delivery vector that imparts activity to a non-conventional platinum(II) metallo-drug. In: Dalton Transactions. 2010 ; Vol. 39, No. 47. pp. 11353-11364.

Bibtex

@article{cce0621822f143b095b5f5eb12439fed,
title = "An androgenic steroid delivery vector that imparts activity to a non-conventional platinum(II) metallo-drug",
abstract = "A range of androgen conjugates with non-conventional platinum(II) complexes have been synthesised with the aim of targeting tumour cells since many display elevated levels of the androgen receptor. The androgenic platinum conjugates are delivered into selected cells with improved efficiency (when compared to their non-steroidal analogues). The act of conjugating an androgen to a platinum(II) complex resulted in synergistic effects between the metallic centre and the steroidal ligand, creating highly potent platinum(II) complexes from the inactive components.",
author = "M Huxley and C Sanchez-Cano and MJ Browning and C Navarro-Ranninger and AG Quiroga and A Rodger and MJ Hannon and Michael Hannon",
year = "2010",
month = jan,
day = "1",
doi = "10.1039/c0dt00838a",
language = "English",
volume = "39",
pages = "11353--11364",
journal = "Dalton Transactions",
issn = "1477-9234",
publisher = "Royal Society of Chemistry",
number = "47",

}

RIS

TY - JOUR

T1 - An androgenic steroid delivery vector that imparts activity to a non-conventional platinum(II) metallo-drug

AU - Huxley, M

AU - Sanchez-Cano, C

AU - Browning, MJ

AU - Navarro-Ranninger, C

AU - Quiroga, AG

AU - Rodger, A

AU - Hannon, MJ

AU - Hannon, Michael

PY - 2010/1/1

Y1 - 2010/1/1

N2 - A range of androgen conjugates with non-conventional platinum(II) complexes have been synthesised with the aim of targeting tumour cells since many display elevated levels of the androgen receptor. The androgenic platinum conjugates are delivered into selected cells with improved efficiency (when compared to their non-steroidal analogues). The act of conjugating an androgen to a platinum(II) complex resulted in synergistic effects between the metallic centre and the steroidal ligand, creating highly potent platinum(II) complexes from the inactive components.

AB - A range of androgen conjugates with non-conventional platinum(II) complexes have been synthesised with the aim of targeting tumour cells since many display elevated levels of the androgen receptor. The androgenic platinum conjugates are delivered into selected cells with improved efficiency (when compared to their non-steroidal analogues). The act of conjugating an androgen to a platinum(II) complex resulted in synergistic effects between the metallic centre and the steroidal ligand, creating highly potent platinum(II) complexes from the inactive components.

U2 - 10.1039/c0dt00838a

DO - 10.1039/c0dt00838a

M3 - Article

C2 - 21031218

VL - 39

SP - 11353

EP - 11364

JO - Dalton Transactions

JF - Dalton Transactions

SN - 1477-9234

IS - 47

ER -