Alpha phase locking predicts residual working memory performance in schizophrenia

Corinna Haenschel; David E Linden; Robert A Bittner; Wolf Singer; Simon Hanslmayr

doi:10.1016/j.biopsych.2010.06.013

Alpha phase locking predicts residual working memory performance in schizophrenia

Corinna Haenschel, David E Linden, Robert A Bittner, Wolf Singer, Simon Hanslmayr

Psychology

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

Working memory (WM) deficits are a core feature of schizophrenia. Recent electrophysiological evidence indicates that the brain systems for visual encoding are especially impaired. However, patients still achieve performance levels clearly above chance, which indicates the existence of residual mechanisms supporting WM encoding. The present study presents evidence that alpha phase locking of the electroencephalogram is a marker for such residual cognitive mechanisms.

Original language	English
Pages (from-to)	595-8
Number of pages	4
Journal	Biological Psychiatry
Volume	68
Issue number	7
DOIs	https://doi.org/10.1016/j.biopsych.2010.06.013
Publication status	Published - 1 Oct 2010

Bibliographical note

Keywords

Alpha Rhythm
Analysis of Variance
Brain Mapping
Discrimination (Psychology)
Electroencephalography
Humans
Memory Disorders
Memory, Short-Term
Neuropsychological Tests
Predictive Value of Tests
Reaction Time
Schizophrenia
Schizophrenic Psychology
Time Factors

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10.1016/j.biopsych.2010.06.013

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title = "Alpha phase locking predicts residual working memory performance in schizophrenia",

abstract = "Working memory (WM) deficits are a core feature of schizophrenia. Recent electrophysiological evidence indicates that the brain systems for visual encoding are especially impaired. However, patients still achieve performance levels clearly above chance, which indicates the existence of residual mechanisms supporting WM encoding. The present study presents evidence that alpha phase locking of the electroencephalogram is a marker for such residual cognitive mechanisms.",

keywords = "Alpha Rhythm, Analysis of Variance, Brain Mapping, Discrimination (Psychology), Electroencephalography, Humans, Memory Disorders, Memory, Short-Term, Neuropsychological Tests, Predictive Value of Tests, Reaction Time, Schizophrenia, Schizophrenic Psychology, Time Factors",

author = "Corinna Haenschel and Linden, {David E} and Bittner, {Robert A} and Wolf Singer and Simon Hanslmayr",

year = "2010",

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T1 - Alpha phase locking predicts residual working memory performance in schizophrenia

AU - Haenschel, Corinna

AU - Linden, David E

AU - Bittner, Robert A

AU - Singer, Wolf

AU - Hanslmayr, Simon

PY - 2010/10/1

Y1 - 2010/10/1

N2 - Working memory (WM) deficits are a core feature of schizophrenia. Recent electrophysiological evidence indicates that the brain systems for visual encoding are especially impaired. However, patients still achieve performance levels clearly above chance, which indicates the existence of residual mechanisms supporting WM encoding. The present study presents evidence that alpha phase locking of the electroencephalogram is a marker for such residual cognitive mechanisms.

AB - Working memory (WM) deficits are a core feature of schizophrenia. Recent electrophysiological evidence indicates that the brain systems for visual encoding are especially impaired. However, patients still achieve performance levels clearly above chance, which indicates the existence of residual mechanisms supporting WM encoding. The present study presents evidence that alpha phase locking of the electroencephalogram is a marker for such residual cognitive mechanisms.

KW - Alpha Rhythm

KW - Analysis of Variance

KW - Brain Mapping

KW - Discrimination (Psychology)

KW - Electroencephalography

KW - Humans

KW - Memory Disorders

KW - Memory, Short-Term

KW - Neuropsychological Tests

KW - Predictive Value of Tests

KW - Reaction Time

KW - Schizophrenia

KW - Schizophrenic Psychology

KW - Time Factors

U2 - 10.1016/j.biopsych.2010.06.013

DO - 10.1016/j.biopsych.2010.06.013

M3 - Article

C2 - 20673879

SN - 0006-3223

VL - 68

SP - 595

EP - 598

JO - Biological Psychiatry

JF - Biological Psychiatry

IS - 7

ER -

Alpha phase locking predicts residual working memory performance in schizophrenia

Abstract

Bibliographical note

Keywords

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