Age should not be a barrier for pulmonary endarterectomy in carefully selected patients

Research output: Contribution to journalLetterpeer-review


  • Jules Hernandez-Sanchez
  • John Dunning
  • Choo Ng
  • Steven Tsui
  • Katherine Bunclark
  • Karen Sheares
  • Dolores Taboada
  • Mark Toshner
  • Joanna Pepke-Zaba
  • David Jenkins
  • John Cannon

Colleges, School and Institutes


Pulmonary endarterectomy (PEA) is the treatment of choice in operable chronic thromboembolic pulmonary hypertension (CTEPH) with excellent long-term outcomes [1]. It is a complex surgical procedure requiring cardiopulmonary bypass and removal of obstructive thromboembolic material during periods of deep hypothermic circulatory arrest [1]. We have observed an increase in the number of older CTEPH patients referred for consideration of PEA, which is consistent with other cardiothoracic surgeries. The UK population is ageing with a projected 3% increase in subjects aged >85 years in the next 20 years [2]. This may be mirrored by patients with CTEPH getting older, as the incidence of pulmonary embolism, which frequently precedes CTEPH, markedly increases with age [3, 4]. Furthermore, an epidemiological analysis by Gall et al. [5] has projected that the annual incidence of CTEPH will increase over the next 10 years. Therefore, the management of CTEPH in older patients is a pertinent topic for investigation.


Original languageEnglish
Article number1701804
Number of pages4
JournalEuropean Respiratory Journal
Issue number6
Publication statusPublished - 7 Dec 2017