Age at menarche and depressive symptoms in older Southern Chinese women: A Mendelian randomization study in the Guangzhou Biobank Cohort Study

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Age at menarche and depressive symptoms in older Southern Chinese women: A Mendelian randomization study in the Guangzhou Biobank Cohort Study. / Yeung, Shiu Lun Au; Jiang, Chaoqiang; Cheng, Kar Keung; Xu, Lin; Zhang, Weisen; Lam, Tai Hing; Leung, Gabriel Matthew; Schooling, C. Mary.

In: Psychiatry Research, 19.09.2017.

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Yeung, Shiu Lun Au ; Jiang, Chaoqiang ; Cheng, Kar Keung ; Xu, Lin ; Zhang, Weisen ; Lam, Tai Hing ; Leung, Gabriel Matthew ; Schooling, C. Mary. / Age at menarche and depressive symptoms in older Southern Chinese women: A Mendelian randomization study in the Guangzhou Biobank Cohort Study. In: Psychiatry Research. 2017.

Bibtex

@article{2f94e6ca1d9240d997333aad31765882,
title = "Age at menarche and depressive symptoms in older Southern Chinese women:: A Mendelian randomization study in the Guangzhou Biobank Cohort Study",
abstract = "To clarify the causal role of age at menarche in depressive symptoms we conducted a Mendelian randomization study using a large Southern Chinese cohort (n=12,233). A genetic allele score was derived using stepwise regression with cross validation. Older age at menarche was not associated with geriatric depression scale score. Our findings suggest that higher rates of depression in women are likely attributable to other factors which require investigation.",
keywords = "China , epidemiology",
author = "Yeung, {Shiu Lun Au} and Chaoqiang Jiang and Cheng, {Kar Keung} and Lin Xu and Weisen Zhang and Lam, {Tai Hing} and Leung, {Gabriel Matthew} and Schooling, {C. Mary}",
year = "2017",
month = sep,
day = "19",
doi = "10.1016/j.psychres.2017.09.040",
language = "English",
journal = "Psychiatry Research",
issn = "0165-1781",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Age at menarche and depressive symptoms in older Southern Chinese women:

T2 - A Mendelian randomization study in the Guangzhou Biobank Cohort Study

AU - Yeung, Shiu Lun Au

AU - Jiang, Chaoqiang

AU - Cheng, Kar Keung

AU - Xu, Lin

AU - Zhang, Weisen

AU - Lam, Tai Hing

AU - Leung, Gabriel Matthew

AU - Schooling, C. Mary

PY - 2017/9/19

Y1 - 2017/9/19

N2 - To clarify the causal role of age at menarche in depressive symptoms we conducted a Mendelian randomization study using a large Southern Chinese cohort (n=12,233). A genetic allele score was derived using stepwise regression with cross validation. Older age at menarche was not associated with geriatric depression scale score. Our findings suggest that higher rates of depression in women are likely attributable to other factors which require investigation.

AB - To clarify the causal role of age at menarche in depressive symptoms we conducted a Mendelian randomization study using a large Southern Chinese cohort (n=12,233). A genetic allele score was derived using stepwise regression with cross validation. Older age at menarche was not associated with geriatric depression scale score. Our findings suggest that higher rates of depression in women are likely attributable to other factors which require investigation.

KW - China

KW - epidemiology

U2 - 10.1016/j.psychres.2017.09.040

DO - 10.1016/j.psychres.2017.09.040

M3 - Article

JO - Psychiatry Research

JF - Psychiatry Research

SN - 0165-1781

ER -