Advances in keratinocyte delivery in burn wound care

Research output: Contribution to journalArticle

Standard

Advances in keratinocyte delivery in burn wound care. / Ter Horst, Britt; Chouhan, Gurpreet; Moiemen, Naiem S.; Grover, Liam M.

In: Advanced Drug Delivery Reviews, Vol. 123, 01.01.2018, p. 18-32.

Research output: Contribution to journalArticle

Harvard

APA

Vancouver

Author

Bibtex

@article{da660bae2fe948faaf11c1ec99dcb55f,
title = "Advances in keratinocyte delivery in burn wound care",
abstract = "This review gives an updated overview on keratinocyte transplantation in burn wounds concentrating on application methods and future therapeutic cell delivery options with a special interest in hydrogels and spray devices for cell delivery.To achieve faster re-epithelialisation of burn wounds, the original autologous keratinocyte culture and transplantation technique was introduced over 3 decades ago. Application types of keratinocytes transplantation have improved from cell sheets to single-cell solutions delivered with a spray system. However, further enhancement of cell culture, cell viability and function in vivo, cell carrier and cell delivery systems remain themes of interest.Hydrogels such as chitosan, alginate, fibrin and collagen are frequently used in burn wound care and have advantageous characteristics as cell carriers.Future approaches of keratinocyte transplantation involve spray devices, but optimisation of application technique and carrier type is necessary.",
keywords = "cell transplantation , burn injury , wound healing , hydrogels , spray application",
author = "{Ter Horst}, Britt and Gurpreet Chouhan and Moiemen, {Naiem S.} and Grover, {Liam M.}",
year = "2018",
month = jan
day = "1",
doi = "10.1016/j.addr.2017.06.012",
language = "English",
volume = "123",
pages = "18--32",
journal = "Advanced Drug Delivery Reviews",
issn = "0169-409X",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Advances in keratinocyte delivery in burn wound care

AU - Ter Horst, Britt

AU - Chouhan, Gurpreet

AU - Moiemen, Naiem S.

AU - Grover, Liam M.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - This review gives an updated overview on keratinocyte transplantation in burn wounds concentrating on application methods and future therapeutic cell delivery options with a special interest in hydrogels and spray devices for cell delivery.To achieve faster re-epithelialisation of burn wounds, the original autologous keratinocyte culture and transplantation technique was introduced over 3 decades ago. Application types of keratinocytes transplantation have improved from cell sheets to single-cell solutions delivered with a spray system. However, further enhancement of cell culture, cell viability and function in vivo, cell carrier and cell delivery systems remain themes of interest.Hydrogels such as chitosan, alginate, fibrin and collagen are frequently used in burn wound care and have advantageous characteristics as cell carriers.Future approaches of keratinocyte transplantation involve spray devices, but optimisation of application technique and carrier type is necessary.

AB - This review gives an updated overview on keratinocyte transplantation in burn wounds concentrating on application methods and future therapeutic cell delivery options with a special interest in hydrogels and spray devices for cell delivery.To achieve faster re-epithelialisation of burn wounds, the original autologous keratinocyte culture and transplantation technique was introduced over 3 decades ago. Application types of keratinocytes transplantation have improved from cell sheets to single-cell solutions delivered with a spray system. However, further enhancement of cell culture, cell viability and function in vivo, cell carrier and cell delivery systems remain themes of interest.Hydrogels such as chitosan, alginate, fibrin and collagen are frequently used in burn wound care and have advantageous characteristics as cell carriers.Future approaches of keratinocyte transplantation involve spray devices, but optimisation of application technique and carrier type is necessary.

KW - cell transplantation

KW - burn injury

KW - wound healing

KW - hydrogels

KW - spray application

U2 - 10.1016/j.addr.2017.06.012

DO - 10.1016/j.addr.2017.06.012

M3 - Article

C2 - 28668483

VL - 123

SP - 18

EP - 32

JO - Advanced Drug Delivery Reviews

JF - Advanced Drug Delivery Reviews

SN - 0169-409X

ER -