Advanced tools for the safety assessment of nanomaterials

Research output: Contribution to journalReview articlepeer-review

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Advanced tools for the safety assessment of nanomaterials. / Fadeel, Bengt; Farcal, Lucian; Hardy, Barry J.; Vázquez-Campos, Socorro; Hristozov, Danail; Marcomini, Antonio; Lynch, Iseult; Valsami-Jones, Eugenia; Alenius, Harri; Savolainen, Kai.

In: Nature Nanotechnology, Vol. 13, No. 7, 06.07.2018, p. 537-543.

Research output: Contribution to journalReview articlepeer-review

Harvard

Fadeel, B, Farcal, L, Hardy, BJ, Vázquez-Campos, S, Hristozov, D, Marcomini, A, Lynch, I, Valsami-Jones, E, Alenius, H & Savolainen, K 2018, 'Advanced tools for the safety assessment of nanomaterials', Nature Nanotechnology, vol. 13, no. 7, pp. 537-543. https://doi.org/10.1038/s41565-018-0185-0

APA

Fadeel, B., Farcal, L., Hardy, B. J., Vázquez-Campos, S., Hristozov, D., Marcomini, A., Lynch, I., Valsami-Jones, E., Alenius, H., & Savolainen, K. (2018). Advanced tools for the safety assessment of nanomaterials. Nature Nanotechnology, 13(7), 537-543. https://doi.org/10.1038/s41565-018-0185-0

Vancouver

Fadeel B, Farcal L, Hardy BJ, Vázquez-Campos S, Hristozov D, Marcomini A et al. Advanced tools for the safety assessment of nanomaterials. Nature Nanotechnology. 2018 Jul 6;13(7):537-543. https://doi.org/10.1038/s41565-018-0185-0

Author

Fadeel, Bengt ; Farcal, Lucian ; Hardy, Barry J. ; Vázquez-Campos, Socorro ; Hristozov, Danail ; Marcomini, Antonio ; Lynch, Iseult ; Valsami-Jones, Eugenia ; Alenius, Harri ; Savolainen, Kai. / Advanced tools for the safety assessment of nanomaterials. In: Nature Nanotechnology. 2018 ; Vol. 13, No. 7. pp. 537-543.

Bibtex

@article{c92365e992bd42dab4a05473ee6260d8,
title = "Advanced tools for the safety assessment of nanomaterials",
abstract = "Engineered nanomaterials (ENMs) have tremendous potential to produce beneficial technological impact in numerous sectors in society. Safety assessment is, of course, of paramount importance. However, the myriad variations of ENM properties makes the identification of specific features driving toxicity challenging. At the same time, reducing animal tests by introducing alternative and/or predictive in vitro and in silico methods has become a priority. It is important to embrace these new advances in the safety assessment of ENMs. Indeed, remarkable progress has been made in recent years with respect to mechanism-based hazard assessment of ENMs, including systems biology approaches as well as high-throughput screening platforms, and new tools are also emerging in risk assessment and risk management for humans and the environment across the whole life-cycle of nano-enabled products. Here, we highlight some of the key advances in the hazard and risk assessment of ENMs.",
keywords = "Nanoscale materials, Nanotoxicology",
author = "Bengt Fadeel and Lucian Farcal and Hardy, {Barry J.} and Socorro V{\'a}zquez-Campos and Danail Hristozov and Antonio Marcomini and Iseult Lynch and Eugenia Valsami-Jones and Harri Alenius and Kai Savolainen",
year = "2018",
month = jul,
day = "6",
doi = "10.1038/s41565-018-0185-0",
language = "English",
volume = "13",
pages = "537--543",
journal = "Nature Nanotechnology",
issn = "1748-3387",
publisher = "Nature Publishing Group",
number = "7",

}

RIS

TY - JOUR

T1 - Advanced tools for the safety assessment of nanomaterials

AU - Fadeel, Bengt

AU - Farcal, Lucian

AU - Hardy, Barry J.

AU - Vázquez-Campos, Socorro

AU - Hristozov, Danail

AU - Marcomini, Antonio

AU - Lynch, Iseult

AU - Valsami-Jones, Eugenia

AU - Alenius, Harri

AU - Savolainen, Kai

PY - 2018/7/6

Y1 - 2018/7/6

N2 - Engineered nanomaterials (ENMs) have tremendous potential to produce beneficial technological impact in numerous sectors in society. Safety assessment is, of course, of paramount importance. However, the myriad variations of ENM properties makes the identification of specific features driving toxicity challenging. At the same time, reducing animal tests by introducing alternative and/or predictive in vitro and in silico methods has become a priority. It is important to embrace these new advances in the safety assessment of ENMs. Indeed, remarkable progress has been made in recent years with respect to mechanism-based hazard assessment of ENMs, including systems biology approaches as well as high-throughput screening platforms, and new tools are also emerging in risk assessment and risk management for humans and the environment across the whole life-cycle of nano-enabled products. Here, we highlight some of the key advances in the hazard and risk assessment of ENMs.

AB - Engineered nanomaterials (ENMs) have tremendous potential to produce beneficial technological impact in numerous sectors in society. Safety assessment is, of course, of paramount importance. However, the myriad variations of ENM properties makes the identification of specific features driving toxicity challenging. At the same time, reducing animal tests by introducing alternative and/or predictive in vitro and in silico methods has become a priority. It is important to embrace these new advances in the safety assessment of ENMs. Indeed, remarkable progress has been made in recent years with respect to mechanism-based hazard assessment of ENMs, including systems biology approaches as well as high-throughput screening platforms, and new tools are also emerging in risk assessment and risk management for humans and the environment across the whole life-cycle of nano-enabled products. Here, we highlight some of the key advances in the hazard and risk assessment of ENMs.

KW - Nanoscale materials

KW - Nanotoxicology

U2 - 10.1038/s41565-018-0185-0

DO - 10.1038/s41565-018-0185-0

M3 - Review article

C2 - 29980781

VL - 13

SP - 537

EP - 543

JO - Nature Nanotechnology

JF - Nature Nanotechnology

SN - 1748-3387

IS - 7

ER -