Adjunctive treatment in juvenile nasopharyngeal angiofibroma: How should we approach recurrence?

Research output: Contribution to journalArticle

Authors

Abstract

A recent case of advanced, recurrent juvenile nasopharyngeal angiofibroma (JNA) at our institution has highlighted the limited evidence regarding adjunctive treatment. We present the case of a 10-year-old boy who is the first to undergo multiplestaged surgical resections alongside vincristine treatment. We performed a review of the literature analyzing the roles of radiation therapy, cytotoxic drugs, and novel targeted agents in JNA relapse. Small cohort studies suggest radiotherapy and flutamide are the most rational treatment options for residual and recurrent JNA. Our review highlights the need for further research into the management of primary and recurrent JNA.

Details

Original languageEnglish
Pages (from-to)235-239
Number of pages5
JournalJournal of pediatric hematology/oncology
Volume38
Issue number3
Publication statusPublished - 13 Apr 2016

Keywords

  • Dexamethasone, Flutamide, Juvenile nasopharyngeal angiofibroma, Radiotherapy