Acoustofluidic waveguides for localized control of acoustic wavefront in microfluidics

Research output: Contribution to journalArticlepeer-review

Standard

Acoustofluidic waveguides for localized control of acoustic wavefront in microfluidics. / Bian, Y.; Guo, F.; Yang, S.; Mao, Z.; Bachman, H.; Tang, S.-Y.; Ren, L.; Zhang, B.; Gong, J.; Guo, X.; Huang, T.J.

In: Microfluidics and Nanofluidics, Vol. 21, No. 8, 132, 08.2017.

Research output: Contribution to journalArticlepeer-review

Harvard

Bian, Y, Guo, F, Yang, S, Mao, Z, Bachman, H, Tang, S-Y, Ren, L, Zhang, B, Gong, J, Guo, X & Huang, TJ 2017, 'Acoustofluidic waveguides for localized control of acoustic wavefront in microfluidics', Microfluidics and Nanofluidics, vol. 21, no. 8, 132. https://doi.org/10.1007/s10404-017-1971-y

APA

Bian, Y., Guo, F., Yang, S., Mao, Z., Bachman, H., Tang, S-Y., Ren, L., Zhang, B., Gong, J., Guo, X., & Huang, T. J. (2017). Acoustofluidic waveguides for localized control of acoustic wavefront in microfluidics. Microfluidics and Nanofluidics, 21(8), [132]. https://doi.org/10.1007/s10404-017-1971-y

Vancouver

Author

Bian, Y. ; Guo, F. ; Yang, S. ; Mao, Z. ; Bachman, H. ; Tang, S.-Y. ; Ren, L. ; Zhang, B. ; Gong, J. ; Guo, X. ; Huang, T.J. / Acoustofluidic waveguides for localized control of acoustic wavefront in microfluidics. In: Microfluidics and Nanofluidics. 2017 ; Vol. 21, No. 8.

Bibtex

@article{18776f218725443cbd8fe7924b8f8a65,
title = "Acoustofluidic waveguides for localized control of acoustic wavefront in microfluidics",
abstract = "The precise manipulation of acoustic fields in microfluidics is of critical importance for the realization of many biomedical applications. Despite the tremendous efforts devoted to the field of acoustofluidics during recent years, dexterous control, with an arbitrary and complex acoustic wavefront, in a prescribed, microscale region is still out of reach. Here, we introduce the concept of acoustofluidic waveguide, a three-dimensional compact configuration that is capable of locally guiding acoustic waves into a fluidic environment. Through comprehensive numerical simulations, we revealed the possibility of forming complex field patterns with defined pressure nodes within a highly localized, pre-determined region inside the microfluidic chamber. We also demonstrated the tunability of the acoustic field profile through controlling the size and shape of the waveguide geometry, as well as the operational frequency of the acoustic wave. The feasibility of the waveguide concept was experimentally verified via microparticle trapping and patterning. Our acoustofluidic waveguiding structures can be readily integrated with other microfluidic configurations and can be further designed into more complex types of passive acoustofluidic devices. The waveguide platform provides a promising alternative to current acoustic manipulation techniques and is useful in many applications such as single-cell analysis, point-of-care diagnostics, and studies of cell–cell interactions.",
keywords = "Acoustofuidics, Waveguides, Patterning, Manipulation",
author = "Y. Bian and F. Guo and S. Yang and Z. Mao and H. Bachman and S.-Y. Tang and L. Ren and B. Zhang and J. Gong and X. Guo and T.J. Huang",
year = "2017",
month = aug,
doi = "10.1007/s10404-017-1971-y",
language = "English",
volume = "21",
journal = "Microfluidics and Nanofluidics",
issn = "1613-4982",
publisher = "Springer",
number = "8",

}

RIS

TY - JOUR

T1 - Acoustofluidic waveguides for localized control of acoustic wavefront in microfluidics

AU - Bian, Y.

AU - Guo, F.

AU - Yang, S.

AU - Mao, Z.

AU - Bachman, H.

AU - Tang, S.-Y.

AU - Ren, L.

AU - Zhang, B.

AU - Gong, J.

AU - Guo, X.

AU - Huang, T.J.

PY - 2017/8

Y1 - 2017/8

N2 - The precise manipulation of acoustic fields in microfluidics is of critical importance for the realization of many biomedical applications. Despite the tremendous efforts devoted to the field of acoustofluidics during recent years, dexterous control, with an arbitrary and complex acoustic wavefront, in a prescribed, microscale region is still out of reach. Here, we introduce the concept of acoustofluidic waveguide, a three-dimensional compact configuration that is capable of locally guiding acoustic waves into a fluidic environment. Through comprehensive numerical simulations, we revealed the possibility of forming complex field patterns with defined pressure nodes within a highly localized, pre-determined region inside the microfluidic chamber. We also demonstrated the tunability of the acoustic field profile through controlling the size and shape of the waveguide geometry, as well as the operational frequency of the acoustic wave. The feasibility of the waveguide concept was experimentally verified via microparticle trapping and patterning. Our acoustofluidic waveguiding structures can be readily integrated with other microfluidic configurations and can be further designed into more complex types of passive acoustofluidic devices. The waveguide platform provides a promising alternative to current acoustic manipulation techniques and is useful in many applications such as single-cell analysis, point-of-care diagnostics, and studies of cell–cell interactions.

AB - The precise manipulation of acoustic fields in microfluidics is of critical importance for the realization of many biomedical applications. Despite the tremendous efforts devoted to the field of acoustofluidics during recent years, dexterous control, with an arbitrary and complex acoustic wavefront, in a prescribed, microscale region is still out of reach. Here, we introduce the concept of acoustofluidic waveguide, a three-dimensional compact configuration that is capable of locally guiding acoustic waves into a fluidic environment. Through comprehensive numerical simulations, we revealed the possibility of forming complex field patterns with defined pressure nodes within a highly localized, pre-determined region inside the microfluidic chamber. We also demonstrated the tunability of the acoustic field profile through controlling the size and shape of the waveguide geometry, as well as the operational frequency of the acoustic wave. The feasibility of the waveguide concept was experimentally verified via microparticle trapping and patterning. Our acoustofluidic waveguiding structures can be readily integrated with other microfluidic configurations and can be further designed into more complex types of passive acoustofluidic devices. The waveguide platform provides a promising alternative to current acoustic manipulation techniques and is useful in many applications such as single-cell analysis, point-of-care diagnostics, and studies of cell–cell interactions.

KW - Acoustofuidics

KW - Waveguides

KW - Patterning

KW - Manipulation

UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-85025436195&partnerID=MN8TOARS

U2 - 10.1007/s10404-017-1971-y

DO - 10.1007/s10404-017-1971-y

M3 - Article

VL - 21

JO - Microfluidics and Nanofluidics

JF - Microfluidics and Nanofluidics

SN - 1613-4982

IS - 8

M1 - 132

ER -