A Systematic Review of the Incidence and Prevalence of Long-Term Neurological Conditions in the UK

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@article{ad9ddfa6031e466fb68c2d02f42a02fe,
title = "A Systematic Review of the Incidence and Prevalence of Long-Term Neurological Conditions in the UK",
abstract = "Background: Updated, robust estimates of the incidence and prevalence of rare long-term neurological conditions in the UK are not available. Global estimates may be misrepresentative as disease aetiology may vary by location. Objectives: To systematically review the incidence and prevalence of long-term neurological conditions in the UK since 1988. Search Strategy: Medline (January 1988 to January 2009), Embase (January 1988 to January 2009), CINAHL (January 1988 to January 2009) and Cochrane CENTRAL databases. Selection Criteria: UK population-based incidence/prevalence studies of long-term neurological conditions since 1988. Exclusion criteria included inappropriate diagnoses and incomprehensive case ascertainment. Data Collection and Analysis: Articles were included based on the selection criteria. Data were extracted from articles with ranges of incidence and prevalence reported. Main Results: Eight studies met the criteria (3 on motor neurone disease; 4 on Huntington's disease; 1 on progressive supranuclear palsy). The incidence of motor neurone disease ranged from 1.06 to 2.4/100,000 person-years. The prevalence ranged from 4.02 to 4.91/100,000. The prevalence of Huntington's disease ranged from 4.0 to 9.94/100,000. The prevalence of progressive supranuclear palsy ranged from 3.1 to 6.5/100,000. Conclusions: The review updates the incidence/prevalence of long-term neurological conditions. Future epidemiological studies must incorporate comprehensive case ascertainment methods and strict diagnostic criteria.",
author = "Tom Hoppitt and Hardev Pall and Melanie Calvert and Paramjit Gill and Guiqing Yao and Jill Ramsay and Gillian James and Jacqueline Conduit and Catherine Sackley",
year = "2011",
month = jan,
day = "1",
doi = "10.1159/000321712",
language = "English",
volume = "36",
pages = "19--28",
journal = "Neuroepidemiology",
issn = "0251-5350",
publisher = "Karger",
number = "1",

}

RIS

TY - JOUR

T1 - A Systematic Review of the Incidence and Prevalence of Long-Term Neurological Conditions in the UK

AU - Hoppitt, Tom

AU - Pall, Hardev

AU - Calvert, Melanie

AU - Gill, Paramjit

AU - Yao, Guiqing

AU - Ramsay, Jill

AU - James, Gillian

AU - Conduit, Jacqueline

AU - Sackley, Catherine

PY - 2011/1/1

Y1 - 2011/1/1

N2 - Background: Updated, robust estimates of the incidence and prevalence of rare long-term neurological conditions in the UK are not available. Global estimates may be misrepresentative as disease aetiology may vary by location. Objectives: To systematically review the incidence and prevalence of long-term neurological conditions in the UK since 1988. Search Strategy: Medline (January 1988 to January 2009), Embase (January 1988 to January 2009), CINAHL (January 1988 to January 2009) and Cochrane CENTRAL databases. Selection Criteria: UK population-based incidence/prevalence studies of long-term neurological conditions since 1988. Exclusion criteria included inappropriate diagnoses and incomprehensive case ascertainment. Data Collection and Analysis: Articles were included based on the selection criteria. Data were extracted from articles with ranges of incidence and prevalence reported. Main Results: Eight studies met the criteria (3 on motor neurone disease; 4 on Huntington's disease; 1 on progressive supranuclear palsy). The incidence of motor neurone disease ranged from 1.06 to 2.4/100,000 person-years. The prevalence ranged from 4.02 to 4.91/100,000. The prevalence of Huntington's disease ranged from 4.0 to 9.94/100,000. The prevalence of progressive supranuclear palsy ranged from 3.1 to 6.5/100,000. Conclusions: The review updates the incidence/prevalence of long-term neurological conditions. Future epidemiological studies must incorporate comprehensive case ascertainment methods and strict diagnostic criteria.

AB - Background: Updated, robust estimates of the incidence and prevalence of rare long-term neurological conditions in the UK are not available. Global estimates may be misrepresentative as disease aetiology may vary by location. Objectives: To systematically review the incidence and prevalence of long-term neurological conditions in the UK since 1988. Search Strategy: Medline (January 1988 to January 2009), Embase (January 1988 to January 2009), CINAHL (January 1988 to January 2009) and Cochrane CENTRAL databases. Selection Criteria: UK population-based incidence/prevalence studies of long-term neurological conditions since 1988. Exclusion criteria included inappropriate diagnoses and incomprehensive case ascertainment. Data Collection and Analysis: Articles were included based on the selection criteria. Data were extracted from articles with ranges of incidence and prevalence reported. Main Results: Eight studies met the criteria (3 on motor neurone disease; 4 on Huntington's disease; 1 on progressive supranuclear palsy). The incidence of motor neurone disease ranged from 1.06 to 2.4/100,000 person-years. The prevalence ranged from 4.02 to 4.91/100,000. The prevalence of Huntington's disease ranged from 4.0 to 9.94/100,000. The prevalence of progressive supranuclear palsy ranged from 3.1 to 6.5/100,000. Conclusions: The review updates the incidence/prevalence of long-term neurological conditions. Future epidemiological studies must incorporate comprehensive case ascertainment methods and strict diagnostic criteria.

U2 - 10.1159/000321712

DO - 10.1159/000321712

M3 - Article

C2 - 21088431

VL - 36

SP - 19

EP - 28

JO - Neuroepidemiology

JF - Neuroepidemiology

SN - 0251-5350

IS - 1

ER -