A quantitative spatial comparison of high-density diffuse optical tomography and fMRI cortical mapping

Research output: Contribution to journalArticle

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A quantitative spatial comparison of high-density diffuse optical tomography and fMRI cortical mapping. / Eggebrecht, Adam T; White, Brian R; Ferradal, Silvina L; Chen, Chunxiao; Zhan, Yuxuan; Snyder, Abraham Z; Dehghani, Hamid; Culver, Joseph P.

In: NeuroImage, Vol. 61, No. 4, 16.07.2012, p. 1120-8.

Research output: Contribution to journalArticle

Harvard

Eggebrecht, AT, White, BR, Ferradal, SL, Chen, C, Zhan, Y, Snyder, AZ, Dehghani, H & Culver, JP 2012, 'A quantitative spatial comparison of high-density diffuse optical tomography and fMRI cortical mapping', NeuroImage, vol. 61, no. 4, pp. 1120-8. https://doi.org/10.1016/j.neuroimage.2012.01.124

APA

Eggebrecht, A. T., White, B. R., Ferradal, S. L., Chen, C., Zhan, Y., Snyder, A. Z., Dehghani, H., & Culver, J. P. (2012). A quantitative spatial comparison of high-density diffuse optical tomography and fMRI cortical mapping. NeuroImage, 61(4), 1120-8. https://doi.org/10.1016/j.neuroimage.2012.01.124

Vancouver

Author

Eggebrecht, Adam T ; White, Brian R ; Ferradal, Silvina L ; Chen, Chunxiao ; Zhan, Yuxuan ; Snyder, Abraham Z ; Dehghani, Hamid ; Culver, Joseph P. / A quantitative spatial comparison of high-density diffuse optical tomography and fMRI cortical mapping. In: NeuroImage. 2012 ; Vol. 61, No. 4. pp. 1120-8.

Bibtex

@article{5159cc27e0ad443a9d614be8ae1b3e6b,
title = "A quantitative spatial comparison of high-density diffuse optical tomography and fMRI cortical mapping",
abstract = "Functional neuroimaging commands a dominant role in current neuroscience research. However its use in bedside clinical and certain neuro-scientific studies has been limited because the current tools lack the combination of being non-invasive, non-ionizing and portable while maintaining moderate resolution and localization accuracy. Optical neuroimaging satisfies many of these requirements, but, until recent advances in high-density diffuse optical tomography (HD-DOT), has been hampered by limited resolution. While early results of HD-DOT have been promising, a quantitative voxel-wise comparison and validation of HD-DOT against the gold standard of functional magnetic resonance imaging (fMRI) has been lacking. Herein, we provide such an analysis within the visual cortex using matched visual stimulation protocols in a single group of subjects (n=5) during separate HD-DOT and fMRI scanning sessions. To attain the needed voxel-to-voxel co-registration between HD-DOT and fMRI image spaces, we implemented subject-specific head modeling that incorporated MRI anatomy, detailed segmentation, and alignment of source and detector positions. Comparisons of the visual responses found an average localization error between HD-DOT and fMRI of 4.4+/-1mm, significantly less than the average distance between cortical gyri. This specificity demonstrates that HD-DOT has sufficient image quality to be useful as a surrogate for fMRI.",
keywords = "Adult, Brain Mapping, Humans, Magnetic Resonance Imaging, Tomography, Optical, Young Adult",
author = "Eggebrecht, {Adam T} and White, {Brian R} and Ferradal, {Silvina L} and Chunxiao Chen and Yuxuan Zhan and Snyder, {Abraham Z} and Hamid Dehghani and Culver, {Joseph P}",
note = "Copyright {\textcopyright} 2012 Elsevier Inc. All rights reserved.",
year = "2012",
month = jul,
day = "16",
doi = "10.1016/j.neuroimage.2012.01.124",
language = "English",
volume = "61",
pages = "1120--8",
journal = "NeuroImage",
issn = "1053-8119",
publisher = "Elsevier",
number = "4",

}

RIS

TY - JOUR

T1 - A quantitative spatial comparison of high-density diffuse optical tomography and fMRI cortical mapping

AU - Eggebrecht, Adam T

AU - White, Brian R

AU - Ferradal, Silvina L

AU - Chen, Chunxiao

AU - Zhan, Yuxuan

AU - Snyder, Abraham Z

AU - Dehghani, Hamid

AU - Culver, Joseph P

N1 - Copyright © 2012 Elsevier Inc. All rights reserved.

PY - 2012/7/16

Y1 - 2012/7/16

N2 - Functional neuroimaging commands a dominant role in current neuroscience research. However its use in bedside clinical and certain neuro-scientific studies has been limited because the current tools lack the combination of being non-invasive, non-ionizing and portable while maintaining moderate resolution and localization accuracy. Optical neuroimaging satisfies many of these requirements, but, until recent advances in high-density diffuse optical tomography (HD-DOT), has been hampered by limited resolution. While early results of HD-DOT have been promising, a quantitative voxel-wise comparison and validation of HD-DOT against the gold standard of functional magnetic resonance imaging (fMRI) has been lacking. Herein, we provide such an analysis within the visual cortex using matched visual stimulation protocols in a single group of subjects (n=5) during separate HD-DOT and fMRI scanning sessions. To attain the needed voxel-to-voxel co-registration between HD-DOT and fMRI image spaces, we implemented subject-specific head modeling that incorporated MRI anatomy, detailed segmentation, and alignment of source and detector positions. Comparisons of the visual responses found an average localization error between HD-DOT and fMRI of 4.4+/-1mm, significantly less than the average distance between cortical gyri. This specificity demonstrates that HD-DOT has sufficient image quality to be useful as a surrogate for fMRI.

AB - Functional neuroimaging commands a dominant role in current neuroscience research. However its use in bedside clinical and certain neuro-scientific studies has been limited because the current tools lack the combination of being non-invasive, non-ionizing and portable while maintaining moderate resolution and localization accuracy. Optical neuroimaging satisfies many of these requirements, but, until recent advances in high-density diffuse optical tomography (HD-DOT), has been hampered by limited resolution. While early results of HD-DOT have been promising, a quantitative voxel-wise comparison and validation of HD-DOT against the gold standard of functional magnetic resonance imaging (fMRI) has been lacking. Herein, we provide such an analysis within the visual cortex using matched visual stimulation protocols in a single group of subjects (n=5) during separate HD-DOT and fMRI scanning sessions. To attain the needed voxel-to-voxel co-registration between HD-DOT and fMRI image spaces, we implemented subject-specific head modeling that incorporated MRI anatomy, detailed segmentation, and alignment of source and detector positions. Comparisons of the visual responses found an average localization error between HD-DOT and fMRI of 4.4+/-1mm, significantly less than the average distance between cortical gyri. This specificity demonstrates that HD-DOT has sufficient image quality to be useful as a surrogate for fMRI.

KW - Adult

KW - Brain Mapping

KW - Humans

KW - Magnetic Resonance Imaging

KW - Tomography, Optical

KW - Young Adult

U2 - 10.1016/j.neuroimage.2012.01.124

DO - 10.1016/j.neuroimage.2012.01.124

M3 - Article

C2 - 22330315

VL - 61

SP - 1120

EP - 1128

JO - NeuroImage

JF - NeuroImage

SN - 1053-8119

IS - 4

ER -