A novel micromanipulation technique for measuring the bursting strength of single mammalian cells

Research output: Contribution to journalArticlepeer-review


Colleges, School and Institutes

External organisations

  • MRC National Institute for Medical Research
  • National Institute for Medical Research, London, UK.
  • British Bio-technology Ltd.


Information about the bursting strength of animal cells is essential if the mechanisms of cell damage in bioreactors are to be understood, and if cell mechanical properties are ever to be related to cell structure and physiology. We have developed a novel cell compression technique that makes it possible to directly measure the bursting strength of single mammalian cells, and to infer information about cell mechanical properties.


Original languageEnglish
Pages (from-to)208-210
Number of pages3
JournalApplied Microbiology and Biotechnology
Issue number2
Publication statusPublished - Nov 1991