A new superfamily of cell surface proteins related to the nerve growth factor receptor

S Mallett, A N Barclay

Research output: Contribution to journalArticlepeer-review

167 Citations (Scopus)

Abstract

In this article Susan Mallett and Neil Barclay discuss the molecular and functional features of a new superfamily of membrane proteins defined by the presence of cysteine-rich motifs originally identified in the low-affinity nerve growth factor receptor. This superfamily includes two lymphocyte proteins of unknown function and two receptors for tumor necrosis factor.

Original languageEnglish
Pages (from-to)220-3
Number of pages4
JournalImmunology Today
Volume12
Issue number7
DOIs
Publication statusPublished - Jul 1991

Keywords

  • Amino Acid Sequence
  • Animals
  • Humans
  • Membrane Proteins
  • Molecular Sequence Data
  • Nerve Growth Factors
  • Receptors, Cell Surface
  • Receptors, Nerve Growth Factor
  • Receptors, Tumor Necrosis Factor
  • Sequence Homology, Nucleic Acid
  • Tumor Necrosis Factor-alpha

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