A case-control study of elderly patients with acute respiratory illness: effect of influenza vaccination on admission to hospital in winter 2003-2004

Rachel Jordan; JI Hawker; Jonathan Ayres; W Tunnicliffe; Peymane Adab; Babatunde Olowokure; J Kai; Richard McManus; Rosaleen Salter; Kar Cheng

doi:10.1016/j.vaccine.2007.09.005

A case-control study of elderly patients with acute respiratory illness: effect of influenza vaccination on admission to hospital in winter 2003-2004

Rachel Jordan, JI Hawker, Jonathan Ayres, W Tunnicliffe, Peymane Adab, Babatunde Olowokure, J Kai, Richard McManus, Rosaleen Salter, Kar Cheng

Applied Health Research

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Abstract

Every winter, hospitals face a large increase in emergency respiratory admissions in elderly people. A case-control study was undertaken to assess the effect of routine influenza vaccine in preventing such admissions among a cohort of UK elderly presenting with acute respiratory illness during winter 2003-2004. 157 hospitalised cases and 639 controls (matched for age, sex and week of consultation) were interviewed. In a winter typical of levels of circulating influenza in recent years, influenza vaccine did not show a protective effect on emergency respiratory admissions overall (adjusted OR 1.2 (95%CI 0.8, 1.9). Policy makers should not rely solely on influenza vaccine routinely having a large effect on winter pressures, and should focus on additional preventive strategies.

Original language	English
Pages (from-to)	7909-13
Number of pages	5
Journal	Vaccine
Volume	25
Issue number	46
DOIs	https://doi.org/10.1016/j.vaccine.2007.09.005
Publication status	Published - 14 Nov 2007

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10.1016/j.vaccine.2007.09.005

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title = "A case-control study of elderly patients with acute respiratory illness: effect of influenza vaccination on admission to hospital in winter 2003-2004",

abstract = "Every winter, hospitals face a large increase in emergency respiratory admissions in elderly people. A case-control study was undertaken to assess the effect of routine influenza vaccine in preventing such admissions among a cohort of UK elderly presenting with acute respiratory illness during winter 2003-2004. 157 hospitalised cases and 639 controls (matched for age, sex and week of consultation) were interviewed. In a winter typical of levels of circulating influenza in recent years, influenza vaccine did not show a protective effect on emergency respiratory admissions overall (adjusted OR 1.2 (95%CI 0.8, 1.9). Policy makers should not rely solely on influenza vaccine routinely having a large effect on winter pressures, and should focus on additional preventive strategies.",

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T1 - A case-control study of elderly patients with acute respiratory illness: effect of influenza vaccination on admission to hospital in winter 2003-2004

AU - Jordan, Rachel

AU - Hawker, JI

AU - Ayres, Jonathan

AU - Tunnicliffe, W

AU - Adab, Peymane

AU - Olowokure, Babatunde

AU - Kai, J

AU - McManus, Richard

AU - Salter, Rosaleen

AU - Cheng, Kar

PY - 2007/11/14

Y1 - 2007/11/14

N2 - Every winter, hospitals face a large increase in emergency respiratory admissions in elderly people. A case-control study was undertaken to assess the effect of routine influenza vaccine in preventing such admissions among a cohort of UK elderly presenting with acute respiratory illness during winter 2003-2004. 157 hospitalised cases and 639 controls (matched for age, sex and week of consultation) were interviewed. In a winter typical of levels of circulating influenza in recent years, influenza vaccine did not show a protective effect on emergency respiratory admissions overall (adjusted OR 1.2 (95%CI 0.8, 1.9). Policy makers should not rely solely on influenza vaccine routinely having a large effect on winter pressures, and should focus on additional preventive strategies.

AB - Every winter, hospitals face a large increase in emergency respiratory admissions in elderly people. A case-control study was undertaken to assess the effect of routine influenza vaccine in preventing such admissions among a cohort of UK elderly presenting with acute respiratory illness during winter 2003-2004. 157 hospitalised cases and 639 controls (matched for age, sex and week of consultation) were interviewed. In a winter typical of levels of circulating influenza in recent years, influenza vaccine did not show a protective effect on emergency respiratory admissions overall (adjusted OR 1.2 (95%CI 0.8, 1.9). Policy makers should not rely solely on influenza vaccine routinely having a large effect on winter pressures, and should focus on additional preventive strategies.

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DO - 10.1016/j.vaccine.2007.09.005

M3 - Article

C2 - 17935837

VL - 25

SP - 7909

EP - 7913

JO - Vaccine

JF - Vaccine

IS - 46

ER -

A case-control study of elderly patients with acute respiratory illness: effect of influenza vaccination on admission to hospital in winter 2003-2004

Abstract

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