A boronic acid-based fluorescent hydrogel for monosaccharide detection

Research output: Contribution to journalArticlepeer-review

Authors

  • Suying Xu
  • Adam Sedgwick
  • Souad Elfeky
  • Ashley Jones
  • Toby Jenkins
  • Steven Bull

Colleges, School and Institutes

Abstract

A boronic acid-based anthracene fluorescent probe was functionalised with an acrylamide unit to incorporate into a hydrogel system for monosaccharide detection. In solution, the fluorescent probe displayed a strong fluorescence turn-on response upon exposure to fructose, and an expected trend in apparent binding constants, as judged by a fluorescence response where d–fructose > d–galactose > d–mannose > d–glucose. The hydrogel incorporating the boronic acid monomer demonstrated the ability to detect monosaccharides by fluorescence with the same overall trend as the monomer in solution with the addition of d–fructose resulting in a 10-fold enhancement (≼0.25 mol/L).

Details

Original languageEnglish
Pages (from-to)112-116
JournalFrontiers of Chemical Science and Engineering
Volume2020
Publication statusPublished - 21 May 2019

ASJC Scopus subject areas