A bioartificial liver - State of the art

Research output: Contribution to journalArticle

Authors

Colleges, School and Institutes

Abstract

End-stage liver disease is treated by liver transplantation, but donor organ shortages remain a serious problem. This has prompted the design of bioartificial liver devices to "bridge" patients until they either recover or receive a liver transplant. In these devices, patient plasma is circulated extracorporeally through a bioreactor that houses liver cells (hepatocytes) sandwiched between artificial plates or capillaries.

Details

Original languageEnglish
Pages (from-to)1005-1009
Number of pages5
JournalScience
Volume295
Issue number5557
Publication statusPublished - 1 Feb 2002