The second extracellular loop of the CGRP receptor: A docking site for vasoprotective ligands

Conner, Alex (Principal Investigator)

Clinical Sciences

Short title	The second extracellular loop of the CGRP receptor: A docking site for vasoprotective ligands
Status	Finished
Effective start/end date	1/01/14 → 31/12/16

Funding

British Heart Foundation

6 Article

Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to Gs
Woolley, M. J., Reynolds, C. A., Simms, J., Walker, C. S., Mobarec, J. C., Garelja, M. L., Conner, A. C., Poyner, D. R. & Hay, D. L., 11 Jul 2017, (E-pub ahead of print) In: Biochemical Pharmacology.
Research output: Contribution to journal › Article › peer-review

Open Access
15 Citations (Scopus)
Relative Antagonism of Mutants of the CGRP Receptor Extracellular Loop 2 Domain (ECL2) Using a Truncated Competitive Antagonist (CGRP8-37): Evidence for the Dual Involvement of ECL2 in the Two-Domain Binding Model
Woolley, M. J., Simms, J., Uddin, S., Poyner, D. R. & Conner, A. C., 1 Aug 2017, In: Biochemistry. 56, 30, p. 3877-3880 4 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
3 Citations (Scopus)

173 Downloads (Pure)
Understanding the molecular functions of the second extracellular loop (ECL2) of the calcitonin gene-related peptide (CGRP) receptor using a comprehensive mutagenesis approach
Woolley, M., Simms, J., Mobarec, J. C., Reynolds, C. A., Poyner, D. R. & Conner, A., 30 May 2017, (E-pub ahead of print) In: Molecular and Cellular Endocrinology.
Research output: Contribution to journal › Article › peer-review

Open Access
File
5 Citations (Scopus)

145 Downloads (Pure)