The Molecular Basis of Regulatory T Cell Recruitment to the Inflamed Liver

Research output

Research output per year 2007 2010 2012

• 17 Article
• 1 Editorial
• 1 Review article

Research output per year

Research output per year

Search results

• 2012

  Human MAIT and CD8 alpha alpha cells develop from a pool of type-17 precommitted CD8(+) T cells

  Walker, LJ., Kang, YH., Smith, MO., Tharmalingham, H., Ramamurthy, N., Fleming, VM., Sahgal, N., Leslie, A., Oo, Y. H., Geremia, A., Scriba, TJ., Hanekom, WA., Lauer, GM., Lantz, O., Adams, D., Powrie, F., Barnes, E. & Klenerman, P., 1 Jan 2012, In: Blood. 119, 2, p. 422-433 12 p.

  Research output: Contribution to journal › Article

  • Mucosal-Associated Invariant T Cells 100%
  • T-Lymphocytes 55%
  • Cord 55%
  • Chemokine Receptors 33%
  • Fetal Blood 29%
  182 Citations (Scopus)
• 2011

  Common lymphatic endothelial and vascular endothelial receptor-1 mediates the transmigration of regulatory T Cells across human hepatic sinusoidal endothelium

  Shetty, S., Weston, C., Oo, Y. H., Westerlund, N., Stamataki, Z., Youster, J., Hubscher, S., Salmi, M., Jalkanen, S., Lalor, P. & Adams, D., 1 Apr 2011, In: Journal of Immunology. 186, 7, p. 4147-4155 9 p.

  Research output: Contribution to journal › Article

  • Portal Hypertension 100%
  • Regulatory T-Lymphocytes 89%
  • Endothelium 80%
  • Blood Vessels 53%
  • Liver 46%
  93 Citations (Scopus)

• Entecavir treatment for chronic hepatitis B: adaptation is not needed for the majority of naïve patients with a partial virological response

  Zoutendijk, R., Reijnders, J. G. P., Brown, A., Zoulim, F., Mutimer, D., Deterding, K., Petersen, J., Hofmann, W. P., Buti, M., Santantonio, T., van Bömmel, F., Pradat, P., Oo, Y. H., Luetgehetmann, M., Berg, T., Hansen, B. E., Wedemeyer, H., Janssen, H. L. A. & VIRGIL Surveillance Study Group, 25 Jul 2011, In: Hepatology. 54, 2, p. 443-51 9 p.

  Research output: Contribution to journal › Article › peer-review

  • entecavir 100%
  • Chronic Hepatitis B 75%
  • Hepatitis B virus 31%
  • DNA 15%
  • Hepatitis B e Antigens 12%
  130 Citations (Scopus)

• Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis

  Syn, W-K., Choi, S. S., Liaskou, E., Karaca, G. F., Agboola, K. M., Oo, Y. H., Mi, Z., Pereira, T. A., Zdanowicz, M., Malladi, P., Chen, Y., Moylan, C., Jung, Y., Bhattacharya, S. D., Teaberry, V., Omenetti, A., Abdelmalek, M. F., Guy, C. D., Adams, D. H., Kuo, P. C., & 3 othersMichelotti, G. A., Whitington, P. F. & Diehl, A. M., Jan 2011, In: Hepatology. 53, 1, p. 106-15 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Hedgehogs 100%
  • Osteopontin 90%
  • Non-alcoholic Fatty Liver Disease 81%
  • Fibrosis 56%
  • Liver Cirrhosis 26%
  167 Citations (Scopus)

  3 Downloads (Pure)
• 2010

  Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease

  Syn, WK., Oo, Y. H., Pereira, TA., Karaca, GF., Jung, Y., Omenetti, A., Witek, RP., Choi, SS., Guy, CD., Fearing, CM., Teaberry, V., Pereira, FEL., Adams, D. & Diehl, AM., 1 Jun 2010, In: Hepatology. 51, 6, p. 1998-2007 10 p.

  Research output: Contribution to journal › Article

  • Natural Killer T-Cells 100%
  • Non-alcoholic Fatty Liver Disease 89%
  • Fibrosis 28%
  • Hedgehogs 21%
  • Liver 20%
  172 Citations (Scopus)

• Altered mRNA expression of telomere binding proteins (TPP1, POT1, RAP1, TRF1 and TRF2) in ulcerative colitis and Crohn's disease

  Da-Silva, N., Arasaradnam, R., Getliffe, K., Sung, E., Oo, Y. H. & Nwokolo, C., Aug 2010, In: Digestive and Liver Disease. 42, 8, p. 544-548 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Telomere-Binding Proteins 100%
  • Ulcerative Colitis 60%
  • Crohn Disease 58%
  • Messenger RNA 35%
  • T-Lymphocytes 25%
  9 Citations (Scopus)

• Analysis of CD161 expression on human CD8(+) T cells defines a distinct functional subset with tissue-homing properties

  Billerbeck, E., Kang, YH., Walker, L., Lockstone, H., Grafmueller, S., Fleming, V., Flint, J., Willberg, CB., Bengsch, B., Seigel, B., Ramamurthy, N., Zitzmann, N., Barnes, EJ., Thevanayagam, J., Bhagwanani, A., Leslie, A., Oo, Y. H., Kollnberger, S., Bowness, P., Drognitz, O., & 4 othersAdams, D., Blum, HE., Thimme, R. & Klenerman, P., 16 Feb 2010, In: National Academy of Sciences. Proceedings. 107, 7, p. 3006-3011 6 p.

  Research output: Contribution to journal › Article

  Open Access

  • T-Lymphocytes 100%
  • interleukin-22 54%
  • Interleukin-17 42%
  • Hepacivirus 37%
  • Interleukin-18 Receptors 34%
  232 Citations (Scopus)

• Autoimmune hepatitis: new paradigms in the pathogenesis, diagnosis, and management

  Hubscher, S., Oo, Y. H. & Adams, D., 1 Jun 2010, In: Hepatology International. 4, 2, p. 475-493 19 p.

  Research output: Contribution to journal › Review article

  • Autoimmune Hepatitis 100%
  • Autoimmune Diseases 51%
  • T-Lymphocytes 48%
  • Intraepithelial Lymphocytes 25%
  • Sclerosing Cholangitis 25%
  79 Citations (Scopus)

• Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver

  Oo, Y. H., Weston, C., Lalor, P., Curbishley, S., Withers, D., Reynolds, G., Shetty, S., Harki, J., Shaw, J., Eksteen, J., Hubscher, S., Walker, L. & Adams, D., 15 Mar 2010, In: Journal of Immunology. 184, 6, p. 2886-2898 13 p.

  Research output: Contribution to journal › Article

  • Regulatory T-Lymphocytes 100%
  • Liver 51%
  • Dendritic Cells 51%
  • Chemokine Receptors 32%
  • Ligands 30%
  153 Citations (Scopus)

• Supporting evidence for natural killer T Cell accumulation in progressive nonalcoholic fatty liver disease?

  Syn, WK. & Oo, Y. H., 1 Jan 2010, In: Hepatology. 51, 1, p. 345-346 2 p.

  Research output: Contribution to journal › Article
  1 Citation (Scopus)

• The role of chemokines in the recruitment of lymphocytes to the liver

  Adams, D. & Oo, Y. H., Feb 2010, In: Journal of Autoimmunity. 34, 1, p. 45-54

  Research output: Contribution to journal › Article › peer-review

  • Chemokines 100%
  • Chemokine Receptors 89%
  • Leukocytes 84%
  • Lymphocytes 73%
  • T-Lymphocyte Subsets 56%
  77 Citations (Scopus)

• The role of chemokines in the recruitment of lymphocytes to the liver

  Oo, Y. H., Shetty, S. & Adams, D., May 2010, In: Digestive Diseases. 28, 1, p. 31-44 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Chemokines 100%
  • Chemokine Receptors 89%
  • Leukocytes 84%
  • Lymphocytes 73%
  • T-Lymphocyte Subsets 56%
  85 Citations (Scopus)
• 2009

  Symptomatic portal biliopathy: a single centre experience from the UK

  Oo, Y. H., Olliff, S., Haydon, G. & Thorburn, D., Feb 2009, In: European Journal of Gastroenterology & Hepatology. 21, 2, p. 206-213

  Research output: Contribution to journal › Article › peer-review

  • Western World 100%
  • Portal Vein 82%
  • Liver Transplantation 73%
  37 Citations (Scopus)
• 2008

  Mycophenolate Mofetil as Second Line Therapy in Autoimmune Hepatitis?

  Hennes, E. M., Adams, D., Oo, Y. H., Schramm, C., Denzer, U., Buggisch, P., Wiegard, C., Kanzler, S., Schuchmann, M., Boecher, W., Galle, P. R. & Lohse, A. W., 2008, In: The American Journal of Gastroenterology. 103, p. 3063-3070 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Autoimmune Hepatitis 100%
  • Mycophenolic Acid 92%
  • Azathioprine 41%
  • Therapeutics 12%
  • Withholding Treatment 5%
  146 Citations (Scopus)

• Persistent pyrexia post-liver transplantation: a unique case of pericardial tuberculosis

  Oo, Y. H. & Syn, W-K., Dec 2008, In: European Journal of Internal Medicine. 19, 8, p. e88-89

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Tacrolimus and cyclosporin doses and blood levels in hepatitis C and alcoholic liver disease patients after liver transplantation

  Oo, Y. H., Dudley, T., Nightingale, P., Haydon, G. & Mutimer, D., 1 Jan 2008, In: Liver Transplantation. 14, 1, p. 81-87 7 p.

  Research output: Contribution to journal › Article

  • Alcoholic Liver Diseases 100%
  • Tacrolimus 85%
  • Hepatitis C 81%
  • Cyclosporine 74%
  • Hepacivirus 73%
  22 Citations (Scopus)
• 2007

  HLA and outcome in living donor liver transplantation in primary biliary cirrhosis: a new piece in the jigsaw?

  Oo, Y. H. & Neuberger, J., Jan 2007, In: Liver Transplantation. 13, 1, p. 8-13 6 p.

  Research output: Contribution to journal › Editorial › peer-review
  2 Citations (Scopus)

• Recurrence of nonviral diseases

  Oo, Y. H. & Neuberger, J., May 2007, In: Clinics in Liver Disease. 11, 2, p. 377-95 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Recurrence 100%
  • Graft Survival 91%
  • Liver Transplantation 79%
  • Allografts 76%
  • Liver Failure 47%
  4 Citations (Scopus)

• The Glasgow alcoholic hepatitis score identifies patients who may benefit from corticosteroids

  Forrest, E. H., Morris, A. J., Stewart, S., Phillips, M., Oo, Y. H., Fisher, N. C., Haydon, G., O'Grady, J. & Day, C. P., 1 Dec 2007, In: Gut. 56, 12, p. 1743-6 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Alcoholic Hepatitis 100%
  • Adrenal Cortex Hormones 58%
  • Survival 15%
  • Pharmacology 4%
  • Therapeutics 3%
  97 Citations (Scopus)