Research output per year
Research output per year
Research output
- 26 Article
- 26 results
Search results
-
2014
Molecular responses of European flounder (Platichthys flesus) chronically exposed to contaminated estuarine sediments
Williams, T., Davies, I. M., Wu, H., Diab, A. M., Webster, L., Viant, M. R., Chipman, J. K., Leaver, M. J., George, S. G., Moffat, C. F. & Robinson, C. D., Aug 2014, In: Chemosphere. 108, p. 152-158 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)475 Downloads (Pure) -
The toxicological application of transcriptomics and epigenomics in zebrafish and other teleosts
Williams, T., Mirbahai, L. & Chipman, J. K., Mar 2014, In: Briefings in Functional Genomics. 13, 2, p. 157-71 15 p.Research output: Contribution to journal › Article › peer-review
40 Citations (Scopus) -
2013
Disruption of DNA methylation via S-adenosylhomocysteine is a key process in high incidence liver carcinogenesis in fish
Mirbahai, L., Southam, A. D., Sommer, U., Williams, T., Bignell, J. P., Lyons, B. P., Viant, M. R. & Chipman, J. K., 23 Apr 2013, In: Journal of Proteome Research. 12, 6, p. 2895-2904Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus)4 Downloads (Pure) -
Transcriptomic responses of European flounder (Platichthys flesus) liver to a brominated flame retardant mixture
Williams, T., Diab, A. M., Gubbins, M., Collins, C., Matejusova, I., Kerr, R., Chipman, J. K., Kuiper, R., Vethaak, A. D. & George, S. G., 15 Oct 2013, In: Aquatic Toxicology. 142-143, p. 45-52 8 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
2011
DNA methylation in liver tumorigenesis in fish from the environment
Mirbahai, L., Yin, G., Bignell, JP., Li, N., Williams, T. & Chipman, J., 1 Nov 2011, In: Epigenetics : official journal of the DNA Methylation Society. 6, 11, p. 1319-1333 15 p.Research output: Contribution to journal › Article › peer-review
39 Citations (Scopus)34 Downloads (Pure) -
Towards a System Level Understanding of Non-Model Organisms Sampled from the Environment: A Network Biology Approach
Williams, T., Turan Jurdzinski, N., Diab, AM., Wu, H., Mackenzie, C., Bartie, KL., Hrydziuszko, O., Lyons, BP., Stentiford, GD., Herbert, J., Abraham, JK., Katsiadaki, I., Leaver, MJ., Taggart, JB., George, SG., Viant, M., Chipman, J. & Falciani, F., 1 Aug 2011, In: PLoS Computational Biology. 7, 8, e1002126.Research output: Contribution to journal › Article › peer-review
Open AccessFile65 Citations (Scopus)161 Downloads (Pure) -
2010
Gene expression analyses of hepatocellular adenoma and hepatocellular carcinoma from the marine flatfish Limanda limanda
Small, HJ., Williams, T., Sturve, J., Chipman, J., Southam, A., Bean, TP., Lyons, BP. & Stentiford, GD., 1 Jan 2010, In: Diseases of Aquatic Organisms. 88, 2, p. 127-141 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)122 Downloads (Pure) -
Hepatic gene expression in flounder chronically exposed to multiply polluted estuarine sediment: Absence of classical exposure 'biomarker' signals and induction of inflammatory, innate immune and apoptotic pathways
Leaver, MJ., Diab, A., Boukouvala, E., Williams, T., Chipman, J., Moffat, CF., Robinson, CD. & George, SG., 18 Feb 2010, In: Aquatic Toxicology. 96, 3, p. 234-245 12 p.Research output: Contribution to journal › Article › peer-review
43 Citations (Scopus)3 Downloads (Pure) -
Hepatic transcriptomic and metabolomic responses in the Stickleback (Gasterosteus aculeatus) exposed to ethinyl-estradiol☆
Katsiadaki, I., Williams, T., Ball, J., Bean, TP., Sanders, MB., Wu, H., Santos, EM., Brown, M., Baker, P., Ortega, F., Falciani, F., Craft, JA., Tyler, CR., Viant, M. & Chipman, J., 5 May 2010, In: Aquatic Toxicology. 97, 3, p. 174-187 14 p.Research output: Contribution to journal › Article › peer-review
70 Citations (Scopus)52 Downloads (Pure) -
Identifying Health Impacts of Exposure to Copper Using Transcriptomics and Metabolomics in a Fish Model
Santos, EM., Ball, JS., Williams, T., Wu, H., Ortega, F., van Aerle, R., Katsiadaki, I., Falciani, F., Viant, M., Chipman, J. & Tyler, CR., 2010, In: Environmental Science & Technology. 44, 2, p. 820-826 7 p.Research output: Contribution to journal › Article › peer-review
130 Citations (Scopus) -
Integrating omic technologies into aquatic ecological risk assessment and environmental monitoring: hurdles, achievements, and future outlook
Van Aggelen, G., Ankley, G. T., Baldwin, W. S., Bearden, D. W., Benson, W. H., Chipman, J. K., Collette, T. W., Craft, J. A., Denslow, N. D., Embry, M. R., Falciani, F., George, S. G., Helbing, C. C., Hoekstra, P. F., Iguchi, T., Kagami, Y., Katsiadaki, I., Kille, P., Liu, L., Lord, P. G., & 13 others, Jan 2010, In: Environmental Health Perspectives. 118, 1, p. 1-5 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile115 Citations (Scopus)168 Downloads (Pure) -
Mapping Drug Physico-Chemical Features to Pathway Activity Reveals Molecular Networks Linked to Toxicity Outcome
Antczak, P., Ortega, F., Chipman, J. & Falciani, F., 1 Aug 2010, In: PLoS ONE. 5, 8, p. e12385Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
2009
Hepatic Transcriptomic and Metabolomic Responses in the Stickleback ( Gasterosteus aculeatus ) Exposed to Environmentally Relevant Concentrations of Dibenzanthracene
Williams, T., Wu, H., Santos, EM., Ball, J., Katsiadaki, I., Brown, MM., Baker, P., Ortega, F., Falciani, F., Craft, JA., Tyler, CR., Chipman, J. & Viant, M., 15 Aug 2009, In: Environmental Science & Technology. 43, 16, p. 6341-6348 8 p.Research output: Contribution to journal › Article › peer-review
62 Citations (Scopus)13 Downloads (Pure) -
Immune- and stress-related transcriptomic responses of Solea senegalensis stimulated with lipopolysaccharide and copper sulphate using heterologous cDNA microarrays
Osuna-Jimenez, I., Williams, T., Prieto-Alamo, MJ., Abril, N., Chipman, J. & Pueyo, C., 1 May 2009, In: Fish & Shellfish Immunology. 26, 5, p. 699-706 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile39 Citations (Scopus)255 Downloads (Pure) -
2008
A cDNA microarray for the three-spined stickleback, Gasterosteus aculeatus L., and analysis of the interactive effects of oestradiol and dibenzanthracene exposures
Geoghegan, F., Katsiadaki, I., Williams, T. & Chipman, J., Jun 2008, In: Journal of Fish Biology. 72, 9, p. 2133-2153 21 p.Research output: Contribution to journal › Article › peer-review
32 Citations (Scopus)7 Downloads (Pure) -
Construction of subtracted EST and normalised cDNA libraries from liver of chemical-exposed three-spined stickleback (Gasterosteus aculeatus) containing pollutant-responsive genes as a resource for transcriptome analysis
Brown, MM., Williams, T., Chipman, J., Katsiadaki, I., Sanders, M. & Craft, JA., Jul 2008, In: Marine Environmental Research. 66, 1, p. 127-130 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)222 Downloads (Pure) -
Hepatic transcriptomic profiles of European flounder (Platichthys flesus) from field sites and computational approaches to predict site from stress gene responses following exposure to model toxicants
Falciani, F., Diab, AM., Sabine, V., Williams, T., Ortega, F., George, SG. & Chipman, J., 11 Nov 2008, In: Aquatic Toxicology. 90, 2, p. 92-101 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile67 Citations (Scopus)293 Downloads (Pure) -
High throughput functional annotation and data mining with the Blast2GO suite
Gotz, S., Garcia-Gomez, JM., Terol, J., Williams, T., Nagaraj, SH., Nueda, MJ., Robles, M., Talon, M., Dopazo, J. & Conesa, A., 2008, In: Nucleic Acids Research. 36, 10, p. 3420-3435 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2310 Citations (Scopus)167 Downloads (Pure) -
High-throughput tissue extraction protocol for NMR- and MS-based metabolomics.
Wu, H., Southam, A., Hines, A. & Viant, M., 15 Jan 2008, In: Analytical Biochemistry. 372, 2, p. 204-12 9 p.Research output: Contribution to journal › Article
439 Citations (Scopus) -
Intraspecific variation in expression of candidate genes for osmoregulation, heme biosynthesis and stress resistance suggests local adaptation in European flounder (Platichthys flesus)
Larsen, PF., Nielsen, EE., Williams, T. & Loeschcke, V., 1 Sept 2008, In: Heredity. 101, 3, p. 247-259 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile47 Citations (Scopus)145 Downloads (Pure) -
The GENIPOL European flounder Platichthys flesus L. toxicogenomics microarray: application for investigation of the response to furunculosis vaccination
Diab, AM., Williams, T., Sabine, VS., Chipman, J. & George, SG., Jun 2008, In: Journal of Fish Biology. 72, 9, p. 2154-2169 16 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus)3 Downloads (Pure) -
Transcriptomic responses of European flounder (Platichthys flesus) to model toxicants
Williams, T., Diab, A., Ortega, F., Sabine, V., Godfrey, R., Falciani, F., Chipman, J. & George, SG., 11 Nov 2008, In: Aquatic Toxicology. 90, 2, p. 83-91 9 p.Research output: Contribution to journal › Article › peer-review
48 Citations (Scopus)14 Downloads (Pure) -
2007
Adaptive differences in gene expression in European flounder (Platichthys flesus)
Larsen, PF., Nielsen, EE., Williams, T., Hemmer-Hansen, J., Chipman, J., Kruhoffer, M., Gronkjaer, P., George, SG., Dyrskjot, L. & Loeschcke, V., 1 Nov 2007, In: Molecular Ecology. 16, 22, p. 4674-4683 10 p.Research output: Contribution to journal › Article › peer-review
95 Citations (Scopus) -
Complex physiological traits as biomarkers of the sub-lethal toxicological effects of pollutant exposure in fishes
McKenzie, DJ., Garofalo, E., Winter, MJ., Ceradini, S., Verweij, F., Day, N., Hayes, R., van der Oost, R., Butler, P., Chipman, J. & Taylor, E., 29 Nov 2007, In: Royal Society of London. Philosophical Transactions B. Biological Sciences. 362, 1487, p. 2043-2059 17 p.Research output: Contribution to journal › Article
49 Citations (Scopus) -
Estimating the Efficiency of Fish Cross-Species cDNA Microarray Hybridization
Cohen, R., Chalifa-Caspi, V., Williams, T., Auslander, M., George, SG., Chipman, J. & Tom, M., 25 Sept 2007, In: Marine Biotechnology. 9, 4, p. 491-499 9 p.Research output: Contribution to journal › Article › peer-review
24 Citations (Scopus)8 Downloads (Pure) -
Handlebar: a flexible, web-based inventory manager for handling barcoded samples
Booth, T., Gilbert, J., Neufeld, JD., Ball, J., Thurston, M., Chipman, J., Joint, I. & Field, D., 1 Mar 2007, In: BioTechniques. 42, 3, p. 300+Research output: Contribution to journal › Article
6 Citations (Scopus)