Hydroxysteroid Dehydrogenase Activity and the Vitamin D Axis in Acute Lung Injury - Mechanistic and Functional Importance

Lavery, Gareth (Co-Investigator)
Lax, Sian (Co-Investigator)
Thickett, David (Principal Investigator)
Mitchell, Tim (Co-Investigator)

Short title	Hydroxysteroid Dehydrogenase Activity and the Vitamin D Axis in Acute Lung Injury - Mechanistic and Functional Importance
Status	Finished
Effective start/end date	1/06/14 → 31/05/17

Funding

Medical Research Council

6 Article

Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS
Mahida, R. Y., Lax, S., Bassford, C. R., Scott, A., Parekh, D., Hardy, R. S., Naidu, B., Matthay, M. A., Stewart, P. M., Cooper, M. C., Perkins, G. D. & Thickett, D. R., 27 Apr 2023, In: Frontiers in immunology. 14, 14 p., 1159831.
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Real-time assessment of neutrophil metabolism and oxidative burst using extracellular flux analysis
Grudzinska, F., Jasper, A., Sapey, E., Thickett, D., Mauro, C., Scott, A. & Barlow, J., 25 Apr 2023, In: Frontiers in immunology. 14, 12 p., 1083072.
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CD14-positive extracellular vesicles in bronchoalveolar lavage fluid as a new biomarker of acute respiratory distress syndrome
Mahida, R. Y., Price, J., Lugg, S. T., Li, H., Parekh, D., Scott, A., Harrison, P., Matthay, M. A. & Thickett, D. R., 6 Apr 2022, In: American journal of physiology. Lung cellular and molecular physiology. 322, 4, p. L617-L624
Research output: Contribution to journal › Article › peer-review

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