First trimester progesterone therapy in women with a history of unexplained recurrent miscarriages: (PROMISE)

Project Details

Layman's description

As many as one in six clinically recognised pregnancies miscarry, and many women suffer the loss of three or more consecutive babies without any apparent reason for such recurrent miscarriage. The economic, societal and psychological costs are tremendous. The PROMISE trial tests whether treatment with progesterone (a natural pregnancy hormone) in the first trimester can reduce the risk of miscarriage in women with a previous history of unexplained recurrent loss. The study is taking place in approximately 50 hospitals across the UK and the Netherlands.
Short titleFirst trimester progesterone therapy in women with a history of unexplained recurrent miscarriages: (PROMISE)
StatusFinished
Effective start/end date1/10/0930/09/14

Funding

  • NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
  • BIRMINGHAM WOMENS NHS TRUST

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