A new tool to support drug discovery: Native LESA mass spectrometry (NESA)

Alderwick, Luke (Co-Investigator)
Cooper, Helen (Principal Investigator)

Biosciences

3 Article

3 results

2022
Mass Spectrometry Detection and Imaging of a Non-Covalent Protein-Drug Complex in Tissue from Orally Dosed Rats
Illes-Toth, E., Hale, O. J., Hughes, J. W., Strittmatter, N., Rose, J., Clayton, B., Sargeant, R., Jones, S., Dannhorn, A., Goodwin, R. J. A. & Cooper, H. J., 13 Jul 2022, (E-pub ahead of print) In: Angewandte Chemie (International Edition) . 61, 36, e202202075.
Research output: Contribution to journal › Article › peer-review

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Quantitative Characterization of Three Carbonic Anhydrase Inhibitors by LESA Mass Spectrometry
Illes-Toth, E., Stubbs, C. J., Sisley, E. K., Bellamy-Carter, J., Simmonds, A. L., Mize, T. H., Styles, I. B., Goodwin, R. J. A. & Cooper, H. J., 6 Jul 2022, In: Journal of the American Society for Mass Spectrometry. 33, 7, p. 1168-1175 8 p.
Research output: Contribution to journal › Article › peer-review

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2020
High-field asymmetric waveform ion mobility spectrometry and native mass spectrometry: analysis of intact protein assemblies and protein complexes
Hale, O. J., Illes-Toth, E., Mize, T. H. & Cooper, H. J., 19 May 2020, In: Analytical Chemistry. 92, 10, p. 6811-6816 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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9 Citations (Scopus)

200 Downloads (Pure)