Sarah Kuehne

Publications

  1. 2014
  2. Published

    Importance of Toxin A, Toxin B, and CDT in virulence of an epidemic Clostridium difficile strain

    Sarah Kuehne, 1 Jan 2014, In: The Journal of Infectious Diseases. 209, 1, p. 83-86 4 p.

    Research output: Contribution to journalArticlepeer-review

  3. Published

    Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo

    Sarah Kuehne, 12 Jan 2014, In: OncoTarget. 5, 7, p. 1761-1769 9 p.

    Research output: Contribution to journalArticlepeer-review

  4. Published

    The flagellin FliC of Clostridium difficile is responsible for pleiotropic gene regulation during in vivo infection

    Sarah Kuehne, 19 May 2014, In: PLoS ONE. 9, 5, e96876.

    Research output: Contribution to journalArticlepeer-review

  5. Published

    A sequence-based approach for prediction of CsrA/RsmA targets in bacteria with experimental validation in Pseudomonas aeruginosa

    Sarah Kuehne, Jun 2014, In: Nucleic Acids Research. 42, 11, p. 6811-6825 15 p.

    Research output: Contribution to journalArticlepeer-review

  6. Published

    Comparison of culture based methods for the isolation of Clostridium difficile from stool samples in a research setting

    Sarah Kuehne, Aug 2014, In: Anaerobe. 28, p. 226-229 4 p.

    Research output: Contribution to journalArticlepeer-review

  7. 2015
  8. Published

    Inflammasome activation contributes to interleukin-23 production in response to Clostridium difficile

    Sarah Kuehne, 27 Jan 2015, In: mBio. 6, 1

    Research output: Contribution to journalArticlepeer-review

  9. Published

    Fluoroquinolone resistance does not impose a cost on the fitness of Clostridium difficile in vitro

    Sarah Kuehne, Mar 2015, In: Antimicrobial Agents and Chemotherapy. 59, 3, p. 1794-1796 3 p.

    Research output: Contribution to journalArticlepeer-review

  10. Published

    The role of flagella in Clostridium difficile pathogenicity

    Sarah Kuehne, May 2015, In: Trends in Microbiology. 23, 5, p. 275-282 8 p.

    Research output: Contribution to journalArticlepeer-review

  11. Published
  12. 2016
  13. Published
  14. Published

    Clostridium difficile flagella predominantly activate TLR5-linked NF-κB pathway in epithelial cells

    Sarah Kuehne, Apr 2016, In: Anaerobe. 38, p. 116-124 9 p.

    Research output: Contribution to journalArticlepeer-review

  15. Published

    The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia

    Sarah Kuehne, 11 Jul 2016, In: Nature Microbiology. 1, 8, 16108.

    Research output: Contribution to journalArticlepeer-review

  16. E-pub ahead of print

    Clostridium difficile Genome Editing Using pyrE Alleles

    Sarah Kuehne, 10 Aug 2016, (E-pub ahead of print) In: Methods in molecular biology. 1476, p. 35-52 18 p.

    Research output: Contribution to journalArticlepeer-review

  17. Published

    Coinfection and Emergence of Rifamycin Resistance during a Recurrent Clostridium difficile Infection

    Sarah Kuehne, Nov 2016, In: Journal of Clinical Microbiology. 54, 11, p. 2689-2694 6 p.

    Research output: Contribution to journalArticlepeer-review

  18. Published
  19. Published
  20. 2017
  21. Published
  22. E-pub ahead of print

    Clostridium difficile flagella induce a pro-inflammatory response in intestinal epithelium of mice in cooperation with toxins

    Sarah Kuehne, 12 Jun 2017, (E-pub ahead of print) In: Scientific Reports. 7, 1, p. 3256

    Research output: Contribution to journalArticlepeer-review

  23. 2018
  24. Published
  25. E-pub ahead of print
  26. Accepted/In press

    Clostridial Genetics: Genetic Manipulation of the Pathogenic Clostridia

    Sarah Kuehne, 10 Dec 2018, (Accepted/In press) Clostridial Genetics: Genetic Manipulation of the Pathogenic Clostridia. American Society of Microbiology

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

  27. 2019
  28. Published

    Which parameters affect biofilm removal with acoustic cavitation? a review

    Nina Vyas, Qian Wang, Rachel Sammons, Sarah Kuehne & Damien Walmsley, 1 May 2019, In: Ultrasound in Medicine & Biology. 45, 5, p. 1044-1055

    Research output: Contribution to journalArticlepeer-review

  29. Published
  30. Published

    Biofilm formation on polyetheretherketone and titanium surfaces

    Sarah Kuehne & Rachel Sammons, Aug 2019, In: Clinical and Experimental Dental Research. 5, 4, p. 427-437 11 p.

    Research output: Contribution to journalArticlepeer-review

  31. Published

    Investigation of the effect of the water to powder ratio on hydraulic cement properties

    Hannah Batchelor, Sarah Kuehne, Paul Cooper & Josette Camilleri, Aug 2019, In: Dental Materials. 35, 8, p. 1146-1154 9 p.

    Research output: Contribution to journalArticlepeer-review

  32. Published

    Phosphorylation and functionality of CdtR in Clostridium difficile

    Sarah Kuehne, 1 Aug 2019, In: Anaerobe. 58, p. 103-109 7 p., 102074.

    Research output: Contribution to journalReview articlepeer-review

  33. Published

    The role of calcium ion release on biocompatibility and antimicrobial properties of hydraulic cements

    Sarah Kuehne, Paul Cooper & Josette Camilleri, 13 Dec 2019, In: Scientific Reports. 9, 10 p., 19019.

    Research output: Contribution to journalArticlepeer-review

  34. 2020
  35. Published
  36. Published
  37. Published

    High speed imaging of biofilm removal from a dental implant model using ultrasonic cavitation

    Nina Vyas, Sarah Kuehne, Rachel Sammons & Damien Walmsley, Jun 2020, In: Dental Materials. 36, 6, p. 733-743 11 p.

    Research output: Contribution to journalArticlepeer-review

  38. Published
  39. Published

    The effect of standoff distance and surface roughness on biofilm disruption using cavitation

    Nina Vyas, Rachel Sammons, Sarah Kuehne, Qian Wang & Damien Walmsley, 30 Jul 2020, In: PLoSONE. 15, 7, e0236428.

    Research output: Contribution to journalArticlepeer-review

  40. Published

    The glucosyltransferase activity of C. difficile Toxin B is required for disease pathogenesis

    Sarah Kuehne & (ed.), 22 Sep 2020, In: PLoS pathogens. 16, 9, 16 p., e1008852.

    Research output: Contribution to journalArticlepeer-review

  41. 2021
  42. Published
  43. Published

    Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection

    Sarah Kuehne, 18 Feb 2021, In: Nature Communications. 12, 1, 1140.

    Research output: Contribution to journalArticlepeer-review

  44. Published
  45. Published