Robert Neely

ORCID: 0000-0002-5023-8960

Colleges, School and Institutes

Willingness to take PhD students

Yes

PhD projects

Robert Neely's research interests are focussed on the development of new ways to study biological systems using fluorescence spectroscopy and imaging. He is particularly interested in the application of enzymes, nature’s molecular machines, to modify DNA.

Robert's research activitiy focuses on sequence-specific DNA modification using the DNA Methyltransferase enzymes and single-molecule fluorescence microscopy

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Most downloaded publications

2-aminopurine as a fluorescent probe of DNA conformation and the DNA–enzyme interface
Robert Neely & Jones, A., 1 May 2015, In : Quarterly Reviews of Biophysics. 48, 2, p. 244-279 25 p.

Research output: Contribution to journal › Article

65 downloads
Human BRCA1-BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection
Ruth Densham, Alexander Garvin, Stone, H. R., Joanna Strachan, Baldock, R. A., Daza-Martin, M., Alice Fletcher, Sarah Blair-Reid, James Beesley, Johal, B., Pearl, L. H., Robert Neely, Keep, N. H., Watts, F. Z. & Jo Morris, 30 May 2016, In : Nature Structural and Molecular Biology.

Research output: Contribution to journal › Article

63 downloads
Combing of Genomic DNA from Droplets Containing Picograms of Material
Robert Neely, 5 Jan 2015, In : ACS Nano. 9, 1, p. 809–816 7 p.

Research output: Contribution to journal › Article

42 downloads
Live-imaging in the CNS: new insights on oligodendrocytes, myelination, and their responses to inflammation
Rassul, S., Robert Neely & Daniel Fulton, 25 Sep 2015, In : Neuropharmacology. 35 p.

Research output: Contribution to journal › Review article

42 downloads
Localizer: fast, accurate, open-source, and modular software package for superresolution microscopy
Dedecker, P., Duwé, S., Robert Neely & Zhang, J., Dec 2012, In : Journal of Biomedical Optics. 17, 12, p. 126008

Research output: Contribution to journal › Article

17 downloads

Recent publications

A general strategy for direct, enzyme-catalyzed conjugation of functional compounds to DNA
Deen, J., Wang, S., Van Snick, S., Leen, V., Janssen, K., Hofkens, J. & Robert Neely, 20 Jun 2018, In : Nucleic Acids Research. 46, 11, e64.

Research output: Contribution to journal › Article

Methyltransferase directed labeling of biomolecules and its applications
Robert Neely, Hofkens, J., Janssen, K., Leen, V., Deen, J. & Vranken, C., 2 May 2017, In : Angewandte Chemie (International Edition) . 56, 19, p. 5182–5200

Research output: Contribution to journal › Review article

Methyltransferase-directed covalent coupling of fluorophores to DNA
Helmer Lauer, M., Vranken, C., Deen, J., Wand, N., Frederickx, W., Vanderlinden, W., Leen, V., Gehlen, M., Hofkens, J. & Robert Neely, 1 May 2017, In : Chemical Science. 8, 5, p. 3804-3811 8 p.

Research output: Contribution to journal › Article

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