Rachel Spruce

Colleges, School and Institutes

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Most downloaded publications

The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer
Martin Read, Seed, R. I., Modasia, B., Kwan, P. P. K., Sharma, N., Vicki Smith, Rachel Spruce, Bansal, S., Gagliano, T., Stratford, A. L., Ismail, T., Wakelam, M. J. O., Dae Kim, Stephen Ward, Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Jan 2016, In : Molecular Carcinogenesis. 55, 1, p. 15-26

Research output: Contribution to journal › Article

181 downloads
Manipulation of PBF/PTTG1IP phosphorylation status ; a potential new therapeutic strategy for improving radioiodine uptake in thyroid and other tumors
Vicki Smith, Neil Sharma, Rachel Spruce, Martin Read, Ryan, G., Kwan, P., Ashley Martin, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jul 2013, In : The Journal of clinical endocrinology and metabolism. 98, 7, p. 2876-2886 11 p.

Research output: Contribution to journal › Article

167 downloads
Circulating tumor DNA as a biomarker and liquid biopsy in head and neck squamous cell carcinoma
Payne, K., Rachel Spruce, Andrew Beggs, Sharma, N., Kong, A., Martin, T., Parmar, S., Praveen, P., Paul Nankivell & Hisham Mehanna, 1 Jul 2018, In : Head & Neck. 40, 7, p. 1598-1604 7 p.

Research output: Contribution to journal › Article

106 downloads
The PTTG1-binding factor (PBF/PTTG1IP) regulates p53 activity in thyroid cells
Martin Read, Seed, R. I., Jim Fong, Modasia, B., Ryan, G. A., Rachel Spruce, Gagliano, T., Vicki Smith, Stratford, A. L., Kwan, P. K., Neil Sharma, Dixon, O. M., Watkinson, J. C., Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Apr 2014, In : Endocrinology. 155, 4, p. 1222-34 13 p.

Research output: Contribution to journal › Article

67 downloads
The Clinical Utility of Cell-Free DNA Measurement in Differentiated Thyroid Cancer: A Systematic Review
Fussey, J. M., Jennifer Bryant, Nikos Batis, Rachel Spruce, Hartley, A., Good, J. S., Christopher McCabe, Kristien Boelaert, Neil Sharma & Hisham Mehanna, 30 Apr 2018, In : Frontiers in Oncology. 8, APR, 132.

Research output: Contribution to journal › Article

65 downloads

Recent publications

Development and validation of a combined hypoxia and immune prognostic classifier for head and neck cancer: hypoxia-immune prognostic classifier for HNC
Brooks, J., Antao Mobre De Menezes, A. R. E., Ibrahim, M., Archer, L., Lal, N., Bagnall, C., Zeidler, S. V. V., Valentine, H., Spruce, R., Batis, N., Bryant, J., Hartley, M., Kaul, B., Ryan, G., Bao, R., Khattri, A., Lee, S., Ogbureke, K. U. E., Middleton, G., Tennant, D. & 7 others, Andrew Beggs, Jon Deeks, West, C. M. L., Jean-Baptiste Cazier, Benjamin Willcox, Seiwert, T. Y. & Hisham Mehanna, 1 Sep 2019, In : Clinical Cancer Research. 25, 17, p. 5315-5328 15 p.

Research output: Contribution to journal › Article

Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma
Jennifer Bryant, Nikos Batis, Franke, A. C., Clancey, G., Hartley, M., Gordon Ryan, Jill Brooks, Andrew Southam, Barnes, N., Jo Parish, Sally Roberts, Farhat Khanim, Rachel Spruce & Hisham Mehanna, 27 Aug 2019, In : OncoTarget. 10, 50, p. 5229-5244 16 p.

Research output: Contribution to journal › Article

Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial
De-ESCALaTE HPV Trial Group, 5 Jan 2019, In : The Lancet. 393, 10166, p. 51-60 10 p.

Research output: Contribution to journal › Article

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