Rachel Spruce

(Former)

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Most downloaded publications

The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer
Martin Read, Vicki Smith, Rachel Spruce, Dae Kim, Stephen Ward, Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Jan 2016, In : Molecular Carcinogenesis. 55, 1, p. 15-26

Research output: Contribution to journal › Article

252 downloads
Manipulation of PBF/PTTG1IP phosphorylation status ; a potential new therapeutic strategy for improving radioiodine uptake in thyroid and other tumors
Vicki Smith, Neil Sharma, Rachel Spruce, Martin Read, Ashley Martin, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jul 2013, In : The Journal of clinical endocrinology and metabolism. 98, 7, p. 2876-2886 11 p.

Research output: Contribution to journal › Article

203 downloads
Circulating tumor DNA as a biomarker and liquid biopsy in head and neck squamous cell carcinoma
Rachel Spruce, Andrew Beggs, Paul Nankivell & Hisham Mehanna, 1 Jul 2018, In : Head & Neck. 40, 7, p. 1598-1604 7 p.

Research output: Contribution to journal › Article

168 downloads
Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial
5 Jan 2019, In : The Lancet. 393, 10166, p. 51-60 10 p.

Research output: Contribution to journal › Article

162 downloads
Pro-invasive effect of proto-oncogene PBF is modulated by an interaction with cortactin
Rachel Spruce, Martin Read, Neil Sharma, Rachel Fletcher, Hisham Mehanna, Kristien Boelaert, Vicki Smith & Christopher McCabe, Dec 2016, In : The Journal of clinical endocrinology and metabolism. 101, 12, p. 4551-4563

Research output: Contribution to journal › Article

111 downloads

Recent publications

A phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol
Anthony Kong, Amanda Kirkham, Jo Parish, Rachel Spruce, Gary Middleton, Christina Yap & Hisham Mehanna, 16 Mar 2020, In : BMJ open. 10, 3, e033009.

Research output: Contribution to journal › Article

Acoustofluidic salivary exosome isolation: a liquid biopsy compatible approach for human papillomavirus–associated oropharyngeal cancer detection
Rachel Spruce, Hisham Mehanna, Jan 2020, In : Journal of Molecular Diagnostics. 22, 1, p. 50-59 10 p.

Research output: Contribution to journal › Article

Collagen induces a more proliferative, migratory and chemoresistant phenotype in head and neck cancer via DDR1
Hisham Mehanna, Rachel Spruce, Wenbin Wei, 9 Nov 2019, In : Cancers. 11, 11, p. 1-16 16 p., 1766 .

Research output: Contribution to journal › Article

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