Rachel Spruce

Colleges, School and Institutes

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Most downloaded publications

The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer
Martin Read, Vicki Smith, Rachel Spruce, Dae Kim, Stephen Ward, Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Jan 2016, In : Molecular Carcinogenesis. 55, 1, p. 15-26

Research output: Contribution to journal › Article

214 downloads
Manipulation of PBF/PTTG1IP phosphorylation status ; a potential new therapeutic strategy for improving radioiodine uptake in thyroid and other tumors
Vicki Smith, Neil Sharma, Rachel Spruce, Martin Read, Ashley Martin, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jul 2013, In : The Journal of clinical endocrinology and metabolism. 98, 7, p. 2876-2886 11 p.

Research output: Contribution to journal › Article

190 downloads
Circulating tumor DNA as a biomarker and liquid biopsy in head and neck squamous cell carcinoma
Rachel Spruce, Andrew Beggs, Paul Nankivell & Hisham Mehanna, 1 Jul 2018, In : Head & Neck. 40, 7, p. 1598-1604 7 p.

Research output: Contribution to journal › Article

143 downloads
Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial
5 Jan 2019, In : The Lancet. 393, 10166, p. 51-60 10 p.

Research output: Contribution to journal › Article

123 downloads
The PTTG1-binding factor (PBF/PTTG1IP) regulates p53 activity in thyroid cells
Martin Read, Jim Fong, Rachel Spruce, Vicki Smith, Neil Sharma, Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Apr 2014, In : Endocrinology. 155, 4, p. 1222-34 13 p.

Research output: Contribution to journal › Article

91 downloads

Recent publications

A phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol
Anthony Kong, Amanda Kirkham, Jo Parish, Rachel Spruce, Gary Middleton, Christina Yap & Hisham Mehanna, 16 Mar 2020, In : BMJ open. 10, 3, e033009.

Research output: Contribution to journal › Article

Collagen induces a more proliferative, migratory and chemoresistant phenotype in head and neck cancer via DDR1
Hisham Mehanna, Rachel Spruce, Wenbin Wei, 9 Nov 2019, In : Cancers. 11, 11, p. 1-16 16 p., 1766 .

Research output: Contribution to journal › Article

Development and validation of a combined hypoxia and immune prognostic classifier for head and neck cancer
Jill Brooks, Albert Menezes Antao Nobre De Menezes, Lucinda Archer, Neeraj Lal, Rachel Spruce, Nikos Batis, Jennifer Bryant, Gordon Ryan, Steve Lee, Gary Middleton, Daniel Tennant & 7 others, Andrew Beggs, Jon Deeks, Jean-Baptiste Cazier, Benjamin Willcox & Hisham Mehanna, Sep 2019, In : Clinical Cancer Research. 25, 17, p. 5315-5328 15 p.

Research output: Contribution to journal › Article

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