Rachel Fletcher

Colleges, School and Institutes

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Most downloaded publications

11β-HSD1 modulates the set-point of brown adipose tissue response to glucocorticoids in male mice
Craig Doig, Rachel Fletcher, , , Dean Larner, , , Andrew Philp & Gareth Lavery, 1 Jun 2017, In: Endocrinology. 158, 6, p. 1964-1976

Research output: Contribution to journal › Article › peer-review

93 downloads
The emergence of the nicotinamide riboside kinases in the regulation of NAD+ metabolism
Rachel Fletcher & Gareth Lavery, 1 Oct 2018, In: Journal of Molecular Endocrinology. 61, 3, p. R107-R121

Research output: Contribution to journal › Article › peer-review

87 downloads
Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures
Yasir Elhassan, Katarina Kluckova, Rachel Fletcher, Antje Garten, Craig Doig, David Cartwright, Claire Burley, Ned Jenkinson, Martin Wilson, Sam Lucas, Ildem Akerman, Alex Seabright, Yu-Chiang Lai, Daniel Tennant, Peter Nightingale, Gareth Wallis, Konstantinos Manolopoulos & 2 others, Andrew Philp & Gareth Lavery, 13 Aug 2019, In: Cell Reports. 28, 7, p. 1717-1728.e6 19 p.

Research output: Contribution to journal › Article › peer-review

84 downloads
Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells
Rachel Fletcher, , Craig Doig, , , Gaby Da Silva Xavier, Antje Garten, Yasir Elhassan, , , Andrew Philp, , & Gareth Lavery, Aug 2017, In: Molecular metabolism. 6, 8, p. 819-832 14 p.

Research output: Contribution to journal › Article › peer-review

79 downloads
Pro-invasive effect of proto-oncogene PBF is modulated by an interaction with cortactin
Rachel Spruce, , Martin Read, Neil Sharma, , , , , Rachel Fletcher, , , , Hisham Mehanna, Kristien Boelaert, Vicki Smith & Christopher McCabe, Dec 2016, In: The Journal of clinical endocrinology and metabolism. 101, 12, p. 4551-4563

Research output: Contribution to journal › Article › peer-review

78 downloads

Recent publications

Induction of the nicotinamide riboside kinase NAD+ salvage pathway in a model of sarcoplasmic reticulum dysfunction
Craig Doig, Aga Zielinska, Rachel Fletcher, , Yasir Elhassan, Antje Garten, David Cartwright, , , , , , Daniel Tennant & Gareth Lavery, 19 Feb 2020, In: Skeletal Muscle. 10, 1, 13 p., 5.

Research output: Contribution to journal › Article › peer-review

Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures
Yasir Elhassan, Katarina Kluckova, Rachel Fletcher, Antje Garten, Craig Doig, David Cartwright, Claire Burley, Ned Jenkinson, Martin Wilson, Sam Lucas, Ildem Akerman, Alex Seabright, Yu-Chiang Lai, Daniel Tennant, Peter Nightingale, Gareth Wallis, Konstantinos Manolopoulos & 2 others, Andrew Philp & Gareth Lavery, 13 Aug 2019, In: Cell Reports. 28, 7, p. 1717-1728.e6 19 p.

Research output: Contribution to journal › Article › peer-review

Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD+ depletion
Rachel Fletcher, Yasir Elhassan, David Cartwright, Craig Doig, Antje Garten, Alpesh Thakker, , , Daniel Tennant, Christian Ludwig & Gareth Lavery, 15 Nov 2018, In: Wellcome Open Research.

Research output: Contribution to journal › Article › peer-review

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