Research output per year
Research output per year
- 1 - 50 out of 61 results
Search results
-
2022
Outcomes following SARS-CoV-2 infection in patients with primary and secondary immunodeficiency in the UK
Outcomes following SARS-CoV-2 infection in patients with primary and secondary immunodeficiency in the UK group, 28 Jan 2022, In: Clinical and Experimental Immunology. 209, 3, p. 247-258 12 p., uxac008.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Downloads (Pure) -
2017
Concurrent OX40 and CD30 ligand blockade abrogates the CD4-driven autoimmunity associated with CTLA4 and PD1 blockade while preserving excellent anti-CD8 tumor immunity
Nawaf, M. G., Ulvmar, M. H., Withers, D. R., McConnell, F. M., Gaspal, F. M., Webb, G. J., Jones, N. D., Yagita, H., Allison, J. P. & Lane, P. J. L., 1 Aug 2017, In: Journal of Immunology. 199, 3, p. 974-981 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)233 Downloads (Pure) -
T cell receptor and cytokine signaling can function at different stages to establish and maintain transcriptional memory and enable T helper cell differentiation
Bevington, S. L., Cauchy, P., Withers, D. R., Lane, P. J. L. & Cockerill, P. N., 3 Mar 2017, In: Frontiers in immunology. 8, 16 p., 204.Research output: Contribution to journal › Review article › peer-review
Open AccessFile12 Citations (Scopus)170 Downloads (Pure) -
2016
OX40, OX40L and Autoimmunity: a Comprehensive Review
Webb, G. J., Hirschfield, G. M. & Lane, P. J. L., Jun 2016, In: Clinical Reviews in Allergy & Immunology. 50, p. 312-332 21 p.Research output: Contribution to journal › Article › peer-review
84 Citations (Scopus) -
2014
Differential requirement for CCR4 and CCR7 during the development of innate and adaptive αβT cells in the adult thymus
Cowan, J. E., McCarthy, N. I., Parnell, S. M., White, A. J., Bacon, A., Serge, A., Irla, M., Lane, P. J. L., Jenkinson, E. J., Jenkinson, W. & Anderson, G., 1 Aug 2014, In: Journal of Immunology. 193, 3, p. 1204-12 9 p.Research output: Contribution to journal › Article › peer-review
51 Citations (Scopus) -
Evolving strategies for cancer and autoimmunity: back to the future
Lane, P. J. L., McConnell, F. M., Anderson, G., Nawaf, M. G., Gaspal, F. M. & Withers, D. R., 14 Apr 2014, In: Frontiers in immunology. 5, 154.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)148 Downloads (Pure) -
Mechanisms of thymus medulla development and function
Anderson, G., Baik, S., Cowan, J. E., Holland, A. M., McCarthy, N. I., Nakamura, K., Parnell, S. M., White, A. J., Lane, P. J. L., Jenkinson, E. J. & Jenkinson, W. E., 2014, In: Current Topics in Microbiology and Immunology. 373, p. 19-47 29 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
2013
Differential requirement for CCR4 in the maintenance but not establishment of the invariant Vγ5(+) dendritic epidermal T-cell pool
Nakamura, K., White, A. J., Parnell, S. M., Lane, P. J., Jenkinson, E. J., Jenkinson, W. E. & Anderson, G., 2013, In: PLoS ONE. 8, 9, p. e74019Research output: Contribution to journal › Article › peer-review
Open Access14 Citations (Scopus) -
Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors
Baik, S., Jenkinson, E. J., Lane, P. J. L., Anderson, G. & Jenkinson, W., Mar 2013, In: European Journal of Immunology. 43, 3, p. 589-94 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile81 Citations (Scopus)557 Downloads (Pure) -
The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development
Cowan, J. E., Parnell, S. M., Nakamura, K., Caamano, J. H., Lane, P. J. L., Jenkinson, E. J., Jenkinson, W. E. & Anderson, G., 8 Apr 2013, In: The Journal of Experimental Medicine. 210, 4, p. 675-81 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile134 Citations (Scopus)239 Downloads (Pure) -
2012
Cutting edge: lymphoid tissue inducer cells maintain memory CD4 T cells within secondary lymphoid tissue
Withers, D. R., Gaspal, F. M., Mackley, E. C., Marriott, C. L., Ross, E. A., Desanti, G. E., Roberts, N. A., White, A. J., Flores-Langarica, A., McConnell, F. M., Anderson, G. & Lane, P. J. L., 2012, In: Journal of Immunology. 189, 5, p. 2094-8 5 p.Research output: Contribution to journal › Article › peer-review
67 Citations (Scopus) -
Developmentally Regulated Availability of RANKL and CD40 Ligand Reveals Distinct Mechanisms of Fetal and Adult Cross-Talk in the Thymus Medulla
Desanti, G. E., Cowan, J. E., Baik, S., Parnell, S. M., White, A. J., Penninger, J. M., Lane, P. J. L., Jenkinson, E. J., Jenkinson, W. & Anderson, G., 2012, In: Journal of Immunology. 189, 12, p. 5519-26 8 p.Research output: Contribution to journal › Article › peer-review
46 Citations (Scopus) -
Lymphoid tissue inducer cells: innate cells critical for CD4+ T cell memory responses?
Lane, P., Gaspal, F., McConnell, F., Kim, MY., Anderson, G. & Withers, D., 1 Jan 2012, In: Annals of the New York Academy of Sciences. 1247, p. 1-15 15 p.Research output: Contribution to journal › Article
12 Citations (Scopus) -
Lymphoid tissue inducer cells: pivotal cells in the evolution of CD4 immunity and tolerance?
Lane, P., Gaspal, F., McConnell, F., Withers, D. & Anderson, G., 1 Jan 2012, In: Frontiers in immunology. 3, p. 24 1 p.Research output: Contribution to journal › Article
Open Access17 Citations (Scopus) -
Rank Signaling Links the Development of Invariant γδ T Cell Progenitors and Aire(+) Medullary Epithelium.
Roberts, NA., White, A., Jenkinson, W., Turchinovich, G., Nakamura, K., Withers, D., McConnell, F., Desanti, G., Benezech, C., Parnell, SM., Cunningham, A., Paolino, M., Penninger, JM., Simon, AK., Nitta, T., Ohigashi, I., Takahama, Y., Caamano, J., Hayday, AC., Lane, P., & 2 others, 14 Mar 2012, In: Immunity. 36, 3, p. 427-437 11 p.Research output: Contribution to journal › Article
115 Citations (Scopus) -
2011
Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice
Gaspal, F., Withers, D., Saini, M., Bekiaris, V., McConnell, F., White, A., Khan, M., Yagita, H., Walker, L., Anderson, G. & Lane, P., 1 Aug 2011, In: The Journal of Experimental Medicine. 208, 8, p. 1579-1584 6 p.Research output: Contribution to journal › Article
43 Citations (Scopus) -
CD117(+)CD3(-)CD56(-)OX40L(high) cells express IL-22 and display an LTi phenotype in human secondary lymphoid tissues
Kim, S., Han, S., Withers, D., Gaspal, F., Bae, J., Baik, S., Shin, HC., Kim, KS., Bekiaris, V., Anderson, G., Lane, P. & Kim, MY., 1 Jun 2011, In: European Journal of Immunology. 41, 6, p. 1563-1572 10 p.Research output: Contribution to journal › Article
34 Citations (Scopus) -
Clonal Analysis Reveals Uniformity in the Molecular Profile and Lineage Potential of CCR9+ and CCR9- Thymus-Settling Progenitors
Desanti, G., Jenkinson, W., Parnell, S., Boudil, A., Gautreau-Rolland, L., Eksteen, J., Ezine, S., Lane, P., Jenkinson, E. & Anderson, G., 18 Mar 2011, In: Journal of Immunology. 186, 9, p. 5227-5235 9 p.Research output: Contribution to journal › Article
13 Citations (Scopus) -
OX40 and CD30 signals in CD4(+) T-cell effector and memory function: a distinct role for lymphoid tissue inducer cells in maintaining CD4(+) T-cell memory but not effector function.
Withers, D., Gaspal, F., Bekiaris, V., McConnell, F., Kim, M., Anderson, G. & Lane, P., 1 Nov 2011, In: Immunological Reviews. 244, 1, p. 134-48 15 p.Research output: Contribution to journal › Article
39 Citations (Scopus) -
2010
IL-4 directs both CD4 and CD8 T cells to produce Th2 cytokines in vitro, but only CD4 T cells produce these cytokines in response to alum-precipitated protein in vivo.
Serre, K., Mohr, E., Gaspal, F., Lane, P., Bird, R., Cunningham, A. & MacLennan, I., 1 Jun 2010, In: Molecular immunology. 47, 10, p. 1914-22 9 p.Research output: Contribution to journal › Article
31 Citations (Scopus) -
Lymphoid tissue inducer cells and the evolution of CD4 dependent high-affinity antibody responses
Lane, P., McConnell, F., Withers, D., Gaspal, F., Saini, M. & Anderson, G., 1 Jan 2010, In: Progress in molecular biology and translational science. 92, p. 159-74 16 p.Research output: Contribution to journal › Article
7 Citations (Scopus) -
Lymphotoxin Signals from Positively Selected Thymocytes Regulate the Terminal Differentiation of Medullary Thymic Epithelial Cells
White, A., Nakamura, K., Jenkinson, W., Saini, M., Sinclair, C., Seddon, B., Narendran, P., Pfeffer, K., Nitta, T., Takahama, Y., Caamano, J., Lane, P., Jenkinson, E. & Anderson, G., 1 Oct 2010, In: Journal of Immunology. 185, 8, p. 4769-4776 8 p.Research output: Contribution to journal › Article
106 Citations (Scopus) -
Non-cirrhotic Intrahepatic Portal Hypertension: Associated Gut Diseases and Prognostic Factors.
Eapen, CE., Nightingale, P., Hubscher, S., Lane, P., Plant, T., Velissaris, D. & Elias, E., 25 May 2010, In: Digestive Diseases and Sciences.Research output: Contribution to journal › Article
52 Citations (Scopus) -
Splenic stromal cells mediate IL-7 independent adult lymphoid tissue inducer cell survival
Hou, T., Mustafa, MZ., Essex, S., Barrington, A., Jenkinson, E., Anderson, G., Lane, P., Withers, D. & Buckley, C., Feb 2010, In: European Journal of Immunology. 40, 2, p. 359-365 7 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus)5 Downloads (Pure) -
2009
Absence of thymus crosstalk in the fetus does not preclude hematopoietic induction of a functional thymus in the adult
Roberts, N., Desanti, G., Withers, D., Scott, HR., Jenkinson, W., Lane, P., Jenkinson, E. & Anderson, G., 1 Sept 2009, In: European Journal of Immunology. 39, 9, p. 2395-402 8 p.Research output: Contribution to journal › Article
23 Citations (Scopus) -
CD30 Is Required for CCL21 Expression and CD4 T Cell Recruitment in the Absence of Lymphotoxin Signals
Bekiaris, V., Gaspal, F., Kim, MY., Withers, D., McConnell, F., Anderson, G. & Lane, P., 1 Apr 2009, In: Journal of Immunology. 182, 8, p. 4771-4775 5 p.Research output: Contribution to journal › Article
16 Citations (Scopus) -
Lymphoid tissue inducer cells: architects of CD4 immune responses in mice and men
Kim, M-Y., Kim, KS., McConnell, F. & Lane, P., 1 Jul 2009, In: Clinical & Experimental Immunology. 157, 1, p. 20-26 7 p.Research output: Contribution to journal › Article
24 Citations (Scopus) -
Lymphoid tissue inducer cells: bridges between the ancient innate and the modern adaptive immune systems
Lane, P., McConnell, F., Withers, D., Gaspal, F., Saini, M. & Anderson, G., 1 Nov 2009, In: Mucosal immunology. 2, 6, p. 472-7 6 p.Research output: Contribution to journal › Article
27 Citations (Scopus) -
NK cells protect secondary lymphoid tissue from cytomegalovirus via a CD30-dependent mechanism
Bekiaris, V., Gaspal, F., McConnell, F., Kim, MY., Withers, D., Sweet, C., Anderson, G. & Lane, P., 1 Oct 2009, In: European Journal of Immunology. 39, 10, p. 2800-2808 9 p.Research output: Contribution to journal › Article
13 Citations (Scopus) -
Synergistic OX40 and CD30 signals sustain CD8(+) T cells during antigenic challenge
Bekiaris, V., Gaspal, F., Kim, MY., Withers, D., Sweet, C., Anderson, G. & Lane, P., 1 Aug 2009, In: European Journal of Immunology. 39, 8, p. 2120-2125 6 p.Research output: Contribution to journal › Article
8 Citations (Scopus) -
The Survival of Memory CD4(+) T Cells within the Gut Lamina Propria Requires OX40 and CD30 Signals
Withers, D., Jaensson, E., Gaspal, F., McConnell, F., Eksteen, J., Anderson, G., Agace, WW. & Lane, P., 1 Oct 2009, In: Journal of Immunology. 183, 8, p. 5079-5084 6 p.Research output: Contribution to journal › Article
35 Citations (Scopus) -
Transplantation of embryonic spleen tissue reveals a role for adult non-lymphoid cells in initiating lymphoid tissue organization.
Glanville, SH., Bekiaris, V., Jenkinson, E., Lane, P., Anderson, G. & Withers, D., 1 Jan 2009, In: European Journal of Immunology. 39, 1, p. 280-9 10 p.Research output: Contribution to journal › Article › peer-review
File14 Citations (Scopus)121 Downloads (Pure) -
2008
Critical synergy of CD30 and OX40 signals in CD4 T cell homeostasis and Th1 immunity to Salmonella
Gaspal, F., Bekiaris, V., Kim, M-Y., Withers, D., Bobat, S., MacLennan, I., Anderson, G., Lane, P. & Cunningham, A., 1 Mar 2008, In: Journal of Immunology. 180, 5, p. 2824-9 6 p.Research output: Contribution to journal › Article
41 Citations (Scopus) -
Heterogeneity of lymphoid tissue inducer cell populations present in embryonic and adult mouse lymphoid tissues
Kim, MY., Rossi, S., Withers, D., McConnell, F., Toellner, K-M., Gaspal, F., Jenkinson, E., Anderson, G. & Lane, P., 1 Jun 2008, In: Immunology. 124, 2, p. 166-74 9 p.Research output: Contribution to journal › Article
47 Citations (Scopus) -
HIV and the architecture of immune responses
Lane, P. & Sekaly, R., 1 Jun 2008, In: Seminars in Immunology. 20, 3, p. 157-158 2 p.Research output: Contribution to journal › Article
1 Citation (Scopus) -
Ly49H(+) NK cells migrate to and protect splenic white pulp stroma from murine cytomegalovirus infection
Bekiaris, V., Timoshenko, O., Hou, T., Toellner, K-M., Shakib, S., Gaspal, F., McConnell, F., Parnell, SM., Withers, D., Buckley, C., Sweet, C., Yokoyama, WM., Anderson, G. & Lane, P., 1 Jan 2008, In: Journal of Immunology. 180, 10, p. 6768-6776 9 p.Research output: Contribution to journal › Article › peer-review
35 Citations (Scopus)10 Downloads (Pure) -
Lymphoid tissue inducer cells in adaptive CD4 T cell dependent responses
Lane, P., Kim, MY., Withers, D., Gaspal, F., Bekiaris, V., Desanti, G., Khan, M., McConnell, F. & Anderson, G., 1 Jun 2008, In: Seminars in Immunology. 20, 3, p. 159-63 5 p.Research output: Contribution to journal › Article
18 Citations (Scopus) -
Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input
White, A., Withers, D., Parnell, SM., Scott, HS., Finke, D., Lane, P., Jenkinson, E. & Anderson, G., 1 Apr 2008, In: European Journal of Immunology. 38, 4, p. 942-7 6 p.Research output: Contribution to journal › Article
68 Citations (Scopus) -
The architects of B and T cell immune responses.
Lane, P., 1 Aug 2008, In: Immunity. 29, 2, p. 171-2 2 p.Research output: Contribution to journal › Article
5 Citations (Scopus) -
2007
Function of CD4+CD3- cells in relation to B and T zone stroma in spleen
Kim, M-Y., McConnell, F., Gaspal, F., White, A., Glanville, S., Bekiaris, V., Walker, L., Caamano, J., Jenkinson, E., Anderson, G. & Lane, P., 15 Feb 2007, In: Blood. 109, 4, p. 1602-10 9 p.Research output: Contribution to journal › Article
73 Citations (Scopus) -
Generating intrathymic microenvironments to establish T-cell tolerance
Anderson, G., Lane, P. & Jenkinson, E., 1 Dec 2007, In: Nature Reviews Immunology. 7, 12, p. 954-63 10 p.Research output: Contribution to journal › Article
149 Citations (Scopus) -
Lymphotoxin-alpha-Dependent and -Independent Signals Regulate Stromal Organiser Cell Homeostasis During Lymph Node Organogenesis
White, A., Carragher, D., Parnell, S., Msaki, A., Perkins, N., Lane, P., Jenkinson, E., Anderson, G. & Caamano, J., 30 May 2007, In: Blood. 110, 6, p. 1950-1959 10 p.Research output: Contribution to journal › Article
50 Citations (Scopus) -
RANK signals from CD4+3- inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla
Rossi, S., Kim, M-Y., Leibbrandt, A., Parnell, S., Jenkinson, W., Glanville, S., McConnell, F., Scott, HS., Penninger, JM., Jenkinson, E., Lane, P. & Anderson, G., 29 May 2007, In: The Journal of Experimental Medicine. 204, p. 1267-1272 6 p.Research output: Contribution to journal › Article
341 Citations (Scopus) -
Role of CD30 in B/T segregation in the spleen
Bekiaris, V., Withers, D., Glanville, SH., McConnell, F., Parnell, S., Kim, M-Y., Gaspal, F., Jenkinson, E., Sweet, C., Anderson, G. & Lane, P., 1 Jan 2007, In: Journal of Immunology. 179, p. 7535-7543 9 p.Research output: Contribution to journal › Article
28 Citations (Scopus) -
Salmonella induces a switched antibody response without germinal centers that impedes the extracellular spread of infection
Cunningham, A., Gaspal, F., Serre, K., Mohr, E., Henderson, I., Scott-Tucker, A., Kenny, S., Khan, M., Toellner, K-M., Lane, P. & MacLennan, I., 15 May 2007, In: Journal of Immunology. 178, 10, p. 6200-7 8 p.Research output: Contribution to journal › Article
136 Citations (Scopus) -
The role of lymphoid tissue inducer cells in splenic white pulp development
Withers, D., Kim, M-Y., Bekiaris, V., Rossi, SW., Jenkinson, W., Gaspal, F., McConnell, F., Caamano, J., Anderson, G. & Lane, P., 1 Nov 2007, In: European Journal of Immunology. 37, 11, p. 3240-5 6 p.Research output: Contribution to journal › Article
43 Citations (Scopus) -
2006
Neonatal and adult CD4+CD3- cells share similar gene expression profile, and neonatal cells upregulate OX40-ligand in response to TL1A (TNFSF15)
Kim, M-Y., Toellner, K-M., White, A., McConnell, F., Gaspal, F., Parnell, S., Jenkinson, E., Anderson, G. & Lane, P., 1 Jan 2006, In: Journal of Immunology. 177, p. 3074-3081 8 p.Research output: Contribution to journal › Article
74 Citations (Scopus) -
The generation of thymus-independent germinal centers depends on CD40 but not on CD154, the T cell-derived CD40-ligand.
Gaspal, F., McConnell, F., Kim, M-Y., Gray, D., Kosco-Vilbois, MH., Raykundalia, C., Botto, M. & Lane, P., 1 Jul 2006, In: European Journal of Immunology. 36, 7, p. 1665-73 9 p.Research output: Contribution to journal › Article
38 Citations (Scopus) -
2005
Both the pre-BCR and the IL-7R alpha are essential for expansion at the pre-BII cell stage in vivo
Erlandsson, L., Licence, S., Gaspal, F., Lane, P., Corcoran, AE. & Martensson, IL., 1 Jun 2005, In: European Journal of Immunology. 35, 6, p. 1969-1976 8 p.Research output: Contribution to journal › Article
22 Citations (Scopus) -
Mice deficient in OX40 and CD30 signals lack memory antibody responses because of deficient CD4 T cell memory
Gaspal, F., Kim, M-Y., McConnell, F., Raykundalia, C., Bekiaris, V. & Lane, P., 1 Jan 2005, In: Journal of Immunology. 174, p. 3891-3896 6 p.Research output: Contribution to journal › Article
133 Citations (Scopus)