Colleges, School and Institutes
Willingness to take PhD students
Peter Hewett’s research and doctoral supervision is focused on the molecular regulation of angiogenic factors and cognate receptors (eg, vascular endothelial cell growth factors), which play key roles in blood vessel growth and function. Many of these factors are also associated with poor outcome in pathologies such as atherosclerosis, diabetes and cancer, making them attractive targets for therapy. Understanding the molecular events leading to the transcription of these genes in vascular cells following insults such as oxidative stress and hyperglycaemia may provide new targets for therapeutic intervention. Dr Hewett and his team are also investigating the potential for anti-gene approaches to modulate target gene expression.