Padma-Sheela Jayaraman

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Publications

  1. 2020
  2. Published

    A Runaway PRH/HHEX-Notch3-Positive Feedback Loop Drives Cholangiocarcinoma and Determines Response to CDK4/6 Inhibition

    Philip Kitchen, Anyaporn Sawasdichai, Simon Afford & Padma-Sheela Jayaraman, 15 Feb 2020, In: Cancer Research. 80, 4, p. 757-770

    Research output: Contribution to journal › Article › peer-review

  3. Published

    Blood platelets stimulate cancer cell extravasation through TGFβ-mediated down-regulation of PRH/HHEX

    Padma-Sheela Jayaraman, 4 Feb 2020, In: Oncogenesis. 9, 10.

    Research output: Contribution to journal › Article › peer-review

  4. 2018
  5. Published

    HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development

    Philip Kitchen, Padma-Sheela Jayaraman, Dec 2018, In: Nature Communications. 9, 1, 14 p., 2704.

    Research output: Contribution to journal › Article › peer-review

  6. Published

    CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism

    Philip Kitchen, Simon Afford, Padma-Sheela Jayaraman, 23 Aug 2018, In: Cancers. 10, 9, 22 p., 283.

    Research output: Contribution to journal › Article › peer-review

  7. Published

    Phosphorylation of PRH/HHEX by Protein Kinase CK2 Regulates Cell Proliferation and Cell Migration in Diverse Cell Types

    Padma-Sheela Jayaraman, 21 Feb 2018, Gene Expression and Regulation in Mammalian Cells: transcription from general aspects . Uchiumi, F. (ed.). InTech

    Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

  8. 2017
  9. E-pub ahead of print

    Protein kinase CK2 inhibition suppresses neointima formation via a proline-rich homeodomain-dependent mechanism

    Padma-Sheela Jayaraman, 18 Sep 2017, In: Vascular Pharmacology.

    Research output: Contribution to journal › Article › peer-review

  10. Published

    Proline-Rich Homeodomain protein (PRH/HHEX) is a suppressor of breast tumour growth

    Rachael Kershaw, Joseph Wragg, Elizabeth Humphreys, John Halsall, Roy Bicknell & Padma-Sheela Jayaraman, 12 Jun 2017, In: Oncogenesis. 6, 6, e346.

    Research output: Contribution to journal › Article › peer-review

  11. Published

    CK2 abrogates the inhibitory effects of PRH/HHEX on prostate cancer cell migration and invasion and acts through PRH to control cell proliferation

    Rachael Kershaw, Elizabeth Humphreys, Padma-Sheela Jayaraman, 30 Jan 2017, In: Oncogenesis. 6, e293.

    Research output: Contribution to journal › Article › peer-review

  12. 2016
  13. Published

    Urokinase-type plasminogen activator (uPA) promotes angiogenesis by attenuating Proline-rich homeodomain protein (PRH) transcription factor activity and de-repressing vascular endothelial growth factor (VEGF) receptor expression

    Padma-Sheela Jayaraman, Rachael Kershaw, 15 Jul 2016, In: Journal of Biological Chemistry. 291, 29, p. 15029-15045

    Research output: Contribution to journal › Article › peer-review

  14. Published

    Misregulation of the proline rich homeodomain (PRH/HHEX) protein in cancer cells and its consequences for tumour growth and invasion

    Padma-Sheela Jayaraman, 13 Feb 2016, In: Cell and Bioscience. 6, 9 p., 12.

    Research output: Contribution to journal › Review article › peer-review

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