Neil Hotchin

Neil Hotchin
ORCID: 0000-0002-1844-7607

Colleges, School and Institutes

Willingness to take PhD students

Yes

PhD projects

Neil Hotchin is a cell biologist with an interest in normal epithelial cell function and in understanding the processes that contribute to diseases such as cancer. He is currently researching the role of Rho family GTPases in regulation of cell function, focusing on:

Regulation of epithelial cell function by Rho family GTPases
The role of syntenin-1 in trafficking of frizzled receptors in breast cancer
The role of Rho GTPases in glioblastoma

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Most downloaded publications

Inference of low and high-grade glioma gene regulatory networks delineates the role of Rnd3 in establishing multiple hallmarks of cancer
Clarke, K., Turan Jurdzinski, N., Mohd Zahari, M., Ryan, K., Durant, S., Shan He, John Heath, Roy Bicknell, Neil Hotchin, Francesco Falciani, Daubon, T., Soulet, F., Herbert, J., Ankers, J., Bjerkvig, R. & Bikfalvi, A., 1 Jul 2015, In : PLoS Genetics. 11, 7, e1005325.

Research output: Contribution to journal › Article

287 downloads
Regulation of platelet derived growth factor signalling by LAR protein tyrosine phosphatase: a quantitative phosphoproteomics study
Almuntafeky, A. R. S., Trushar Patel, Andrew Creese, Michael Tomlinson, Carina Hellberg, John Heath, Neil Hotchin & Debbie Cunningham, 1 Jun 2016, In : Molecular and Cellular Proteomics. p. 1823-1836

Research output: Contribution to journal › Article

245 downloads
Differential Regulation of Adhesion Complex Turnover by ROCK1 and ROCK2.
Lock, FE., Ryan, KR., Natalie Poulter, Parsons, M. & Neil Hotchin, 1 Jan 2012, In : PLoS ONE. 7, 2, p. e31423

Research output: Contribution to journal › Article

121 downloads
Electroporation and microinjection successfully deliver single-stranded and duplex DNA into live cells as detected by FRET measurements
Bamford, R. A., Zhao, Z., Neil Hotchin, Iain Styles, Gerard Nash, Jim Tucker & Roy Bicknell, 22 Apr 2014, In : PLoS ONE. 9, 4, e95097.

Research output: Contribution to journal › Article

113 downloads
The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts
Braga, V. M., Laura Machesky, Hall, A. & Neil Hotchin, 1997, In : Journal of Cell Biology. 137, 6, p. 1421-31 11 p.

Research output: Contribution to journal › Article

104 downloads

Recent publications

A novel form of JARID2 is required for differentiation in lineage-committed cells
Al-Raawi, D., Jones, R., Susanne Wijesinghe, John Halsall, Petric, M., Sally Roberts, Neil Hotchin & Aditi Kanhere, 1 Feb 2019, In : The EMBO journal. 38, 3, e98449.

Research output: Contribution to journal › Article

Quantitative Phosphoproteomics Reveals a Role for Collapsin Response Mediator Protein 2 in PDGF-Induced Cell Migration
Almuntafeky, A. R. S., Szyroka, J., Shabana Begum, Michael Tomlinson, Neil Hotchin, John Heath & Debbie Cunningham, 2017, In : Scientific Reports. 7, 3970.

Research output: Contribution to journal › Article

LAR protein tyrosine phosphatase regulates focal adhesions via CDK1
Almuntafeky, A. R. S., Trushar Patel, Cowell, A., Michael Tomlinson, Carina Hellberg, John Heath, Debbie Cunningham & Neil Hotchin, 1 Aug 2016, In : Journal of Cell Science. 129, p. 2962-2971

Research output: Contribution to journal › Article

View all (38)

Recent Activities

Examination of PhD thesis
Neil Hotchin (Examiner)
9 Aug 2016

Activity: Examination

European Cytoskeletal Forum
Neil Hotchin (Speaker)
20 Jun 2016 → 23 Jun 2016

Activity: Talk or presentation › Academic conference

Examination of PhD thesis
Neil Hotchin (Examiner)
25 Jan 2016

Activity: Examination

View all (5)