Michelangelo Certo

Colleges, School and Institutes

External positions

, Queen Mary University of London

20172018

University College London

20162017

University of Calabria

20102015

Biography

Dr. Michelangelo Certo obtained his degree in Pharmaceutical Chemistry and Technology cum laude in 2010 and his PhD in Cellular Biochemistry and Pharmacology in 2013 from the University of Calabria (Italy). Post-doc at the Centre of Preclinical and Translational Pharmacology, University of Calabria (2013-2015), he worked on the characterization of the interactions between the immune system and the brain subjected to ischemic injury for the identification of novel immunotherapeutics for stroke. In 2015 he was appointed as an expert in the field of Pharmacology (BIO/14) by the Department Council at the School of Pharmacy of the University of Calabria. In 2016 he was awarded a research fellowship  by the Italian Society of Pharmacology and he joined the University College London to apply his research to the field of pain. His research has always been devoted to the study of inflammatory mechanisms controlling immunity and inflammation with a focus on therapeutic innovation in the context of cell trafficking, target identification and therapeutic exploitation, reparative and regenerative therapeutics. In 2017 he moved to the William Harvey Research Institute at the Barts and The London School of Medicine and Dentistry at Queen Mary, University of London, where he focused on the investigation of the metabolic control of immune cell effector functions and the implications of the metabolic dependence of immune responses in inflammatory conditions. In 2018 he joined the Institute of Inflammation and Ageing at the University of Birmingham as Senior Researcher in Metabolism and Inflammation to investigate the interconnections between metabolic and inflammatory pathways and how systemic and local metabolic alterations in diseases with an inflammatory component lead to aberrant immune cell responses, which favour both the establishment and the propagation of inflammation. In particular, he focuses on unveiling how specific metabolites, including lactate and fatty acids, can surprisingly act as signalling molecules modulating many aspects the immune-inflammatory response.

Qualifications

Master of Research in Neuroscience

Researcher qualification obtained in the frame of L&S apprenticeship programme of Italia Lavoro SpA. Aim of the research activity: to apply a drug-repurposing approach to identify immunomodulatory compounds that could represent good candidates for the treatment of different neurodegenerative diseases.

 

Doctor of Philosophy (Ph.D.) in Pharmacology

Ph.D. course in Cellular Biochemistry and Pharmacology. Dissertation in pharmacology/neuroscience: “Preclinical characterization of a new therapeutic strategy for cerebral ischemia identified by drug repurposing of a macrolide antibiotic”.

 

M.Sc. in Pharmaceutical Chemistry and Technology

Thesis in pharmacology/neuroscience entitled: “Neuroprotective effects of leptin in a model of focal cerebral ischemia in rats”.