Michael Tomlinson

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Publications

  1. 2001
  2. Published

    A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signalling pathways via PLCgamma2 in B cells

    Michael Tomlinson, 1 Jan 2001, In: BMC Immunology. 2, 1, p. 4 1 p.

    Research output: Contribution to journal › Article

  3. 2003
  4. Published

    T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression

    Michael Tomlinson, 17 Nov 2003, In: PLoS Biology. 1, 2, p. 271-287 17 p.

    Research output: Contribution to journal › Article › peer-review

  5. 2004
  6. Published

    Expression and function of Tec, Itk and Btk in lymphocytes: evidence for a unique role for Tec

    Michael Tomlinson, 15 Mar 2004, In: Molecular and Cellular Biology. 24, 6, p. 2455-2466 12 p.

    Research output: Contribution to journal › Article

  7. Published

    SHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase

    Michael Tomlinson, Victoria Heath, Steve Watson, 8 Oct 2004, In: Journal of Biological Chemistry. 279, p. 55089-55096 8 p.

    Research output: Contribution to journal › Article

  8. 2006
  9. Published

    Differentiation of murine committed megakaryocytic progenitors isolated by a novel strategy reveals the complexity of GATA and Ets factor involvement in megakaryocytopoiesis and an unexpected potential role for GATA-6

    Stephanie Dumon, Victoria Heath, Michael Tomlinson & Jon Frampton, 1 May 2006, In: Experimental Hematology. 34, 5, p. 654-63 10 p.

    Research output: Contribution to journal › Article

  10. Published

    A comprehensive proteomics and genomics analysis reveals novel transmembrane proteins in human platelets and mouse megakaryocytes including G6b-B, a novel immunoreceptor tyrosine-based inhibitory motif protein

    Yotis Senis, Michael Tomlinson, Stephanie Dumon, Victoria Heath, Jennifer Spalton, Roy Bicknell, Jon Frampton, Ashley Martin, Mike Wakelam & Steve Watson, 27 Dec 2006, In: Molecular and Cellular Proteomics. 6, p. 548-564 17 p.

    Research output: Contribution to journal › Article

  11. 2007
  12. Published

    The C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signaling cascade.

    Michael Tomlinson, Steve Watson & Andrew Pearce, 27 Apr 2007, In: Journal of Biological Chemistry. 282, 17, p. 12397-409 13 p.

    Research output: Contribution to journal › Article

  13. Published

    Glycoprotein VI oligomerization in cell lines and platelets

    Oscar Berlanga, Jon Frampton, Michael Tomlinson & Steve Watson, 1 May 2007, In: Journal of Thrombosis and Haemostasis. 5, 5, p. 1026-33 8 p.

    Research output: Contribution to journal › Article

  14. Published

    Collagen promotes sustained glycoprotein VI signaling in platelets and cell lines

    Michael Tomlinson, Simon Calaminus, Oscar Berlanga, Jocelyn Auger & Steve Watson, 1 Nov 2007, In: Journal of Thrombosis and Haemostasis. 5, 11, p. 2274-2283 10 p.

    Research output: Contribution to journal › Article

  15. 2008
  16. Published

    G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2.

    Jun Mori, Jennifer Spalton, Michael Tomlinson, Yotis Senis & Steve Watson, 19 Dec 2008, In: Journal of Biological Chemistry. 283, 51, p. 35419-27 9 p.

    Research output: Contribution to journal › Article › peer-review

  17. 2009
  18. Published

    Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains

    Steven Thomas, Victoria Heath, John Herbert, Roy Bicknell, Yotis Senis, Fedor Berditchevski, Steve Watson & Michael Tomlinson, 1 Jan 2009, In: Biochemical Journal. 417, 1, p. 391-

    Research output: Contribution to journal › Article › peer-review

  19. Published

    The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis

    Yotis Senis, Michael Tomlinson, Alexandra Mazharian, Kristin Kornerup, Jocelyn Auger, Steven Thomas, Tarvinder Dhanjal, Neena Kalia & Steve Watson, 14 May 2009, In: Blood. 113, 20, p. 4942-4954 13 p.

    Research output: Contribution to journal › Article › peer-review

  20. Published

    Platelet tetraspanins: small but interesting.

    Michael Tomlinson, 9 Sep 2009, In: Journal of Thrombosis and Haemostasis.

    Research output: Contribution to journal › Article

  21. 2010
  22. Published

    CLEC-2 activates Syk through dimerization

    Craig Hughes, Alice Pollitt, Jun Mori, Michael Tomlinson, Klaus Futterer & Steve Watson, 12 Feb 2010, In: Blood. 115, 14, p. 2947-2955

    Research output: Contribution to journal › Article › peer-review

  23. 2011
  24. Published

    Tetraspanin microdomains: fine-tuning platelet function.

    Elizabeth Haining & Michael Tomlinson, 1 Apr 2011, In: Biochemical Society Transactions. 39, 2, p. 518-23 6 p.

    Research output: Contribution to journal › Article

  25. Published

    The emerging role of tetraspanin microdomains on endothelial cells.

    John Herbert, Victoria Heath, Roy Bicknell & Michael Tomlinson, 1 Dec 2011, In: Biochemical Society Transactions. 39, 6, p. 1667-73 7 p.

    Research output: Contribution to journal › Article

  26. 2012
  27. Published

    Circulating DBP level and prognosis in operated lung cancer: an exploration of pathophysiology.

    Alice Turner, Michael Tomlinson, Fedor Berditchevski & Babu Naidu, 3 May 2012, In: The European respiratory journal. 41, 2, p. 410-416 7 p.

    Research output: Contribution to journal › Article › peer-review

  28. Published

    The TspanC8 subgroup of tetraspanins interacts with a disintegrin and metalloprotease 10 (ADAM10) and regulates its maturation and cell surface expression

    Elizabeth Haining, Steve Watson, Jon Frampton, Paloma Garcia & Michael Tomlinson, 16 Nov 2012, In: Journal of Biological Chemistry. 287, 47, p. 39753-39765 13 p.

    Research output: Contribution to journal › Article › peer-review

  29. 2015
  30. Published

    SLAP/SLAP2 prevent excessive platelet (hem)ITAM signaling in thrombosis and ischemic stroke in mice

    Craig Hughes, Steve Watson, Michael Tomlinson, 1 Jan 2015, In: Blood. 125, 1, p. 185-194 10 p.

    Research output: Contribution to journal › Article › peer-review

  31. 2016
  32. Published

    TspanC8 tetraspanins and a disintegrin and metalloprotease 10 (ADAM10) interact via their extracellular regions: evidence for distinct binding mechanisms for different TspanC8 proteins

    Peter Noy, Jasmeet Reyat, Ed Rainger & Michael Tomlinson, 12 Feb 2016, In: Journal of Biological Chemistry. 291, 7, p. 3145-3157 13 p.

    Research output: Contribution to journal › Article › peer-review

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