Michael Sheppard

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Publications

  1. Published

    Radioiodine treatment of hyperthyroidism - prognostic factors for outcome

    Amit Allahabadia, Michael Sheppard, Stephen Gough & Jayne Franklyn, 1 Aug 2001, In: Journal of Clinical Endocrinology and Metabolism. 86, 8, p. 3611-3617 7 p.

    Research output: Contribution to journal › Article

  2. Published

    Long-acting octreotide and prolonged-release lanreotide formulations have different pharmacokinetic profiles

    Michael Sheppard, 1 Jul 2005, In: Journal of Clinical Pharmacology. 45(7), p. 836-844 9 p.

    Research output: Contribution to journal › Article

  3. Published

    Does acromegaly enhance mortality?

    John Ayuk & Michael Sheppard, 1 Mar 2008, In: Reviews in endocrine & metabolic disorders. 9, 1, p. 33-9 7 p.

    Research output: Contribution to journal › Article

  4. Published

    Switch in expression of 11beta-hydroxysteroid dehydrogenase (11beta-HSD) mRNAs in pituitary adenomas

    John Ayuk, Kristien Boelaert, Michael Sheppard, Martin Hewison, Paul Stewart & Neil Gittoes, 1 Jan 2001, p. OR34-1.

    Research output: Contribution to conference (unpublished) › Paper

  5. Published

    Letter re: Monitoring the Response to Treatment in Acromegaly

    John Ayuk, Michael Sheppard, Andrew Bates & Paul Stewart, 10 May 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 8, p. 4980-4980 1 p.

    Research output: Contribution to journal › Letter

  6. Published

    Growth hormone and pituitary radiotherapy, but not serum insulin-like growth factor-I concentrations, predict excess mortality in patients with acromegaly

    John Ayuk, Michael Sheppard, Paul Stewart & Andrew Bates, 1 Jan 2004, In: Journal of Clinical Endocrinology and Metabolism. 89, 4, p. 1613-1617 5 p.

    Research output: Contribution to journal › Article

  7. Published

    Efficacy of Sandostatin LAR (long-acting somatostatin analogue) is similar in patients with untreated acromegaly and in those previously treated with surgery and/or radiotherapy

    John Ayuk, Suzanne Stewart, Paul Stewart & Michael Sheppard, 1 Jan 2004, In: Clinical Endocrinology. 60(3), p. 375-381 7 p.

    Research output: Contribution to journal › Article

  8. Published

    Long-term safety and efficacy of depot long-acting somatostatin analogs for the treatment of acromegaly

    John Ayuk, Paul Stewart & Michael Sheppard, 1 Sep 2002, In: Journal of Clinical Endocrinology and Metabolism. 87, 9, p. 4142-4146 5 p.

    Research output: Contribution to journal › Article

  9. Published

    Expression of 11beta hydroxysteroid dehydrogenase isozyme mRNAs in normal pituitary and pituitary adenomas

    John Ayuk, Kristien Boelaert, Michael Sheppard, Martin Hewison, Paul Stewart & Neil Gittoes, 1 Jan 2001, p. OC17.

    Research output: Contribution to conference (unpublished) › Paper

  10. Published

    The role of growth hormone-receptor antagonism in relation to acromegaly

    John Ayuk & Michael Sheppard, 1 Nov 2004, In: Expert Opinion on Pharmacotherapy. 5(11), p. 2279-2285 7 p.

    Research output: Contribution to journal › Review article

  11. Published

    Evidence for the Use of IGF-I as a Predictor of Mortality in Acromegaly Is Lacking

    John Ayuk, Michael Sheppard, Andrew Bates & Paul Stewart, 1 Nov 2004, In: Journal of Clinical Endocrinology and Metabolism. 89, 11, p. 5867-5868 2 p.

    Research output: Contribution to journal › Article

  12. Published

    Growth hormone and its disorders

    John Ayuk & Michael Sheppard, 1 Jan 2006, In: Postgraduate Medical Journal. 82, 963, p. 24-30 7 p.

    Research output: Contribution to journal › Review article

  13. Published

    Management of acromegaly in Latin America: expert panel recommendations

    Michael Sheppard, 1 Jun 2010, In: Pituitary. 13, 2, p. 168-175 8 p.

    Research output: Contribution to journal › Article

  14. Published

    Clinical, quality of life, and economic value of acromegaly disease control

    Michael Sheppard, 1 Sep 2011, In: Pituitary. 14, 3, p. 284-294 11 p.

    Research output: Contribution to journal › Article

  15. Published

    The Network for the Enhancement of Endocrinology and Oncology Knowledge: A case-based consideration of current practice in Cushing's disease and acromegaly

    Michael Sheppard, 1 Dec 2009, In: Best practice & research. Clinical endocrinology & metabolism. 23, p. S1-S4

    Research output: Contribution to journal › Article

  16. Published

    Serum TSH concentration as a novel predictor of malignancy in thyroid nodules investigated by fine needle aspiration

    Kristien Boelaert, Roger Holder, Michael Sheppard & Jayne Franklyn, 5 Sep 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4295-4301 7 p.

    Research output: Contribution to journal › Article

  17. Published

    The assessment of thyroid neoplasia

    Kristien Boelaert, Jayne Franklyn, Michael Sheppard, 1 Jan 2007, Clinical Endocrine Oncology.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  18. Published

    Pituitary tumor transforming gene (PTTG) and thyroid disease

    Kristien Boelaert, Christopher McCabe, Jattinder Khaira, Neil Gittoes, Margaret Eggo, Michael Sheppard & Jayne Franklyn, 1 Jan 2001, p. 1-215. 215 p.

    Research output: Contribution to conference (unpublished) › Paper

  19. Published

    Gender, age, goitre type and sereum TSH predict thyroid neoplasia in 1500 patients with thyroid enlargement investigated by FNAC

    Kristien Boelaert, Michael Sheppard & Jayne Franklyn, 1 Jan 2004, p. OC21.

    Research output: Contribution to conference (unpublished) › Abstract

  20. Published

    Simple clinical and biochemical parameters predict thyroid neoplasia and malignancy in 1500 patients investigated by FNAB

    Kristien Boelaert, Roger Holder, Michael Sheppard & Jayne Franklyn, 1 Jan 2004.

    Research output: Contribution to conference (unpublished) › Paper

  21. Published

    Disruption of the SH3 domain of PTTG reveals distinct mechanisms of FGF-induction and cell transformation

    Kristien Boelaert, Lesley Tannahill, Jasbir Moore, Lawrence Young, Michael Sheppard, Jayne Franklyn, Neil Gittoes & Christopher McCabe, 1 Jan 2002.

    Research output: Contribution to conference (unpublished) › Abstract

  22. Published

    Sodium iodide gene expression is a potential prognostic indicator for thyroid cancer and is inhibited by PTTG

    Kristien Boelaert, Margaret Eggo, Neil Gittoes, Michael Sheppard, Jayne Franklyn & Christopher McCabe, 1 Jan 2003, p. OC37.

    Research output: Contribution to conference (unpublished) › Abstract

  23. Published

    A potential role for human securin/PTTG in the developing fetal brain

    Kristien Boelaert, Christopher McCabe, Lesley Tannahill, Neil Gittoes, Michael Sheppard, Mark Kilby & Jayne Franklyn, 1 Jan 2003, p. P164.

    Research output: Contribution to conference (unpublished) › Abstract

  24. Published

    Prediction of cure and risk of hypothyroidism in patients receiving 131I for hyperthyroidism.

    Kristien Boelaert, Michael Sheppard, Roger Holder, Stephen Gough & Jayne Franklyn, 1 Jan 2009, In: Clinical Endocrinology. 70, 1, p. 129-38 10 p.

    Research output: Contribution to journal › Article

  25. Published

    NIS gene expression is a potential prognostic indicator for thyroid cancer and is inhibited by PTTG

    Kristien Boelaert, Lesley Tannahill, Margaret Eggo, Neil Gittoes, Michael Sheppard, Jayne Franklyn & Christopher McCabe, 1 Jan 2003, p. 28. 1 p.

    Research output: Contribution to conference (unpublished) › Abstract

  26. Published

    The SH3 domain of PTTG differentially mediates FGF-2 transactivation and cell transformation

    Kristien Boelaert, Lesley Tannahill, Jasbir Moore, Lawrence Young, Michael Sheppard, Neil Gittoes, Jayne Franklyn & Christopher McCabe, 1 Jan 2002, p. OR 40-42.

    Research output: Contribution to conference (unpublished) › Paper

  27. Published

    PTTG and FGF-2 -novel potential molecular indicators for thyroid cancer

    Kristien Boelaert, Christopher McCabe, Lesley Tannahill, Neil Gittoes, Michael Sheppard & Jayne Franklyn, 1 Jan 2002, p. OR 61-62.

    Research output: Contribution to conference (unpublished) › Paper

  28. Published

    Using an increased fixed dose of 1311 (600MBq) leads to improved outcome in patients with hyperthyroidism

    Kristien Boelaert, Michael Sheppard, Stephen Gough & Jayne Franklyn, 1 Jan 2007, p. P312.

    Research output: Contribution to conference (unpublished) › Abstract

  29. Published

    Sodium iodide symporter (NIS) gene expression is a potential prognostic indicator for thyroid cancer and is inhibited by pituitary tumor transforming gene

    Kristien Boelaert, Lesley Tannahill, Margaret Eggo, Neil Gittoes, Michael Sheppard, Jayne Franklyn & Christopher McCabe, 1 Jan 2003.

    Research output: Contribution to conference (unpublished) › Paper

  30. Published

    Pituitary tumour transforming gene and fibroblast growth factor 2 expression: potential prognostic indicators in differentiated thyroid cancer

    Kristien Boelaert, Christopher McCabe, Lesley Tannahill, Neil Gittoes, Roger Holder, Jo Bradwell, Michael Sheppard & Jayne Franklyn, 1 May 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 5, p. 2341-2347 7 p.

    Research output: Contribution to journal › Article

  31. Published

    The Skeletal System in Hyperthyroidism

    Michael Sheppard & Neil Gittoes, 1 Jan 2005, The Thyroid, 9th edition. Vol. Ch 40.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  32. Published

    The Skeletal System in Hypothyroidism

    Neil Gittoes & Michael Sheppard, 1 Jan 2005, The Thyroid, 9th edition. Vol. Ch 62.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  33. Published

    Modulation of 11beta-hydroxysteroid dehydrogenase by pro-inflammatory cytokines in osteoblasts: an autocrine switch from glucocorticoid inactivation to activation

    Mark Cooper, Iwona Bujalska, Elizabeth Rabbitt, Elizabeth Walker, Rosemary Bland, Michael Sheppard, Martin Hewison & Paul Stewart, 1 Jun 2001, In: Journal of Bone and Mineral Research. 16, 6, p. 1037-1044 8 p.

    Research output: Contribution to journal › Article

  34. Published

    Collection and storage conditions of serum for the analysis of thyroglobulin

    Michael Sheppard, 1 Jan 2002, p. pp36.

    Research output: Contribution to conference (unpublished) › Paper

  35. Published

    Anaplastic carcinoma of the thyroid presenting with hyperthyroidism

    Michael Sheppard & Jayne Franklyn, 1 Jan 2002, p. P59.

    Research output: Contribution to conference (unpublished) › Abstract

  36. Published

    Weight gain following treatment of hyperthyroidism

    Roger Holder, Michael Sheppard & Jayne Franklyn, 1 Aug 2001, In: Clinical Endocrinology. 55, 2, p. 233-239 7 p.

    Research output: Contribution to journal › Article

  37. Published

    Quantitation of thyroglobulin (Tg) mRNA in peripheral blood of thyroid cancer patients

    Margaret Eggo, Michael Sheppard, Jayne Franklyn, 1 Jan 2001, p. 226. 1 p.

    Research output: Contribution to conference (unpublished) › Abstract

  38. Published

    Expression of 11beta-hydroxysteroid dehydrogenase in rat osteoblastic cells: a functional role for intracrine regulation of glucocorticoid metabolism in bone

    Elizabeth Rabbitt, Rosemary Bland, Mark Cooper, Michael Sheppard, Paul Stewart & Martin Hewison, 1 Jun 2001, In: Journal of Cellular Biochemistry. 81, 3, p. 453-462 10 p.

    Research output: Contribution to journal › Article

  39. Published

    Atrial fibrillation predicts mortality in hyperthyroidism

    Jayne Franklyn, Faizel Osman, Michael Sheppard & Michael Gammage, 1 Jan 2003.

    Research output: Contribution to conference (unpublished) › Abstract

  40. Published

    Thyroid function and mortality in patients treated for hyperthyroidism

    Jayne Franklyn, Michael Sheppard, 6 Jul 2005, In: JAMA The Journal of the American Medical Association. 294, 1, p. 71-80 10 p.

    Research output: Contribution to journal › Article

  41. Published

    Atrial fibrillation predicts mortality in thyrotoxicosis

    Jayne Franklyn, Faizel Osman, Michael Sheppard & Michael Gammage, 1 Jan 2002, p. 102. 1 p.

    Research output: Contribution to conference (unpublished) › Paper

  42. Published

    Association between serum TSH and free T4 concentrations and occurrence of atrial fibrillation in a large community-based population of elderly subjects. The Birmingham Elderly Thyroid Study

    Michael Gammage, Jim Parle, Jayne Franklyn, Sue Wilson, Roger Holder, Michael Sheppard, Andrea Roalfe, 1 Jan 2005, p. OC34.

    Research output: Contribution to conference (unpublished) › Abstract

  43. Published

    Association between serum free T4 concentration and atrial fibrillation

    Michael Gammage, Jim Parle, Roger Holder, Lesley Roberts, Richard Hobbs, Sue Wilson, Michael Sheppard & Jayne Franklyn, 14 May 2007, In: Archives of Internal Medicine. 167, 9, p. 928-934 7 p.

    Research output: Contribution to journal › Article

  44. Published

    Thyroid Function Tests

    Neil Gittoes, Jayne Franklyn, Michael Sheppard, 1 Jan 2001, Endocrinology (4th Edition). Vol. 2 Ch 97.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  45. Published

    Guidelines for the treatment of growth hormone excess and growth hormone deficiency in adults

    Michael Sheppard, 1 Sep 2008, In: Journal of endocrinological investigation. 31, 9, p. 820-838 19 p.

    Research output: Contribution to journal › Review article

  46. Published

    The interleukin-1 receptor antagonist gene shows no allelic association with three autoimmune diseases

    Amit Allahabadia, Caroline Gordon, Michael Sheppard, Jayne Franklyn, Jun 1999, In: Thyroid. 9, 6, p. 627-8 2 p.

    Research output: Contribution to journal › Article › peer-review

  47. Published

    Angiotensin-converting enzyme (ACE)-inhibitor suppresses glomerular transforming growth factor-beta (TGF-beta) receptor expression in experimental diabetes in rats

    Ann Logan, Michael Sheppard, 6 Apr 2001, In: Diabetologia. 44, 4, p. 495-500 6 p.

    Research output: Contribution to journal › Article

  48. Published

    An audit of management of differentiated thyroid cancer in specialist and non-specialist clinic settings

    Harish Kumar, Roger Holder, Michael Sheppard & Jayne Franklyn, 1 Jun 2001, In: Clinical Endocrinology. 54, 6, p. 719-723 5 p.

    Research output: Contribution to journal › Article

  49. Published

    Basic Fibroblast Growth Factor Is an Autocrine Factor for Rat Thyroid Follicular Cells

    Michael Sheppard, 1 Jan 1991, In: Annals of the New York Academy of Sciences. 638, 1, p. 453-455 3 p.

    Research output: Contribution to journal › Article › peer-review

  50. Published

    Lack of association between serum TSH or free T4 and body mass index in euthyroid subjects

    Kristien Boelaert, Michael Sheppard, Roger Holder, Stephen Gough & Jayne Franklyn, 1 Feb 2006, In: Clinical Endocrinology. 64, 2, p. 125-128 4 p.

    Research output: Contribution to journal › Article

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