Michael Sheppard
Publications
- 2014
- Published
A paradigm shift in the monitoring of patients with acromegaly: last available growth hormone may overestimate risk
Mark Sherlock, Raoul Reulen, Aurora Aragon Alonso, John Ayuk, Michael Sheppard, Michael Hawkins, Andrew Bates & Paul Stewart, Feb 2014, In: The Journal of clinical endocrinology and metabolism. 99, 2, p. 478-85 8 p.Research output: Contribution to journal › Article › peer-review
- 2011
- Published
Clinical, quality of life, and economic value of acromegaly disease control
Michael Sheppard, 1 Sep 2011, In: Pituitary. 14, 3, p. 284-294 11 p.Research output: Contribution to journal › Article
- Published
Medical therapy in acromegaly.
Mark Sherlock & Michael Sheppard, 1 May 2011, In: Nature Reviews Endocrinology. 7, 5, p. 291-300 10 p.Research output: Contribution to journal › Article
- 2010
- Published
A randomized controlled trial of the effect of thyroxine replacement on cognitive function in community-living elderly subjects with subclinical hypothyroidism: the birmingham elderly thyroid study
Jim Parle, Lesley Roberts, Sue Wilson, Andrea Roalfe, Sayeed Haque, Michael Sheppard, Jayne Franklyn & Richard Hobbs, 1 Aug 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 8, p. 3623-32 10 p.Research output: Contribution to journal › Article
- Published
Management of acromegaly in Latin America: expert panel recommendations
Michael Sheppard, 1 Jun 2010, In: Pituitary. 13, 2, p. 168-175 8 p.Research output: Contribution to journal › Article
- Published
- 2009
- Published
The Network for the Enhancement of Endocrinology and Oncology Knowledge: A case-based consideration of current practice in Cushing's disease and acromegaly
Michael Sheppard, 1 Dec 2009, In: Best practice & research. Clinical endocrinology & metabolism. 23, p. S1-S4Research output: Contribution to journal › Article
- Published
ACTH Deficiency, Higher Doses of Hydrocortisone Replacement, and Radiotherapy Are Independent Predictors of Mortality in Patients with Acromegaly
Mark Sherlock, Raoul Reulen, Aurora Aragon Alonso, John Ayuk, Michael Sheppard, Michael Hawkins, Andrew Bates & Paul Stewart, 1 Nov 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 11, p. 4216-4223 8 p.Research output: Contribution to journal › Article
- Published
Medical Therapy in Patients with Acromegaly: Predictors of Response and Comparison of Efficacy of Dopamine Agonists and Somatostatin Analogues
Mark Sherlock, Aurora Aragon Alonso, Raoul Reulen, John Ayuk, Michael Sheppard, Andrew Bates & Paul Stewart, 1 Apr 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1255-1263 9 p.Research output: Contribution to journal › Article
- Published
- 2008
- Published
Monitoring disease activity using growth hormone and insulin like growth factor-I in the follow up of 501 patients with acromegaly.
Mark Sherlock, Aurora Aragon Alonso, Raoul Reulen, John Ayuk, Michael Sheppard, Andrew Bates & Paul Stewart, 27 Oct 2008, In: Clinical Endocrinology.Research output: Contribution to journal › Article
- Published
Guidelines for the treatment of growth hormone excess and growth hormone deficiency in adults
Michael Sheppard, 1 Sep 2008, In: Journal of endocrinological investigation. 31, 9, p. 820-838 19 p.Research output: Contribution to journal › Review article
- Published
Does acromegaly enhance mortality?
John Ayuk & Michael Sheppard, 1 Mar 2008, In: Reviews in endocrine & metabolic disorders. 9, 1, p. 33-9 7 p.Research output: Contribution to journal › Article
- 2007
- Published
Association between serum free T4 concentration and atrial fibrillation
Michael Gammage, Jim Parle, Roger Holder, Lesley Roberts, Richard Hobbs, Sue Wilson, Michael Sheppard & Jayne Franklyn, 14 May 2007, In: Archives of Internal Medicine. 167, 9, p. 928-934 7 p.Research output: Contribution to journal › Article
- Published
Growth hormone assay standardization: an important clinical advance.
Michael Sheppard, 1 Feb 2007, In: Clinical Endocrinology. 66, 2, p. 157-61 5 p.Research output: Contribution to journal › Article
- Published
Cardiovascular manifestations of hyperthyroidism before and after antithyroid therapy; a matched case-control study
Faizel Osman, Jayne Franklyn, Roger Holder, Michael Sheppard & Michael Gammage, 9 Jan 2007, In: Journal of the American College of Cardiology. 49, 1, p. 71-81 11 p.Research output: Contribution to journal › Article
- Published
The assessment of thyroid neoplasia
Kristien Boelaert, Jayne Franklyn, Michael Sheppard, 1 Jan 2007, Clinical Endocrine Oncology.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Published
- 2006
- Published
Growth hormone therapy does not induce cancer
Michael Sheppard, 1 Oct 2006, In: Nature clinical practice. Endocrinology & metabolism. 2, 10, p. 532-533 2 p.Research output: Contribution to journal › Article
- Published
Prevalence of subclinical thyroid dysfunction and its relation to socioeconomic deprivation in the elderly: a community based cross-sectional survey
Jim Parle, Lesley Roberts, Andrea Roalfe, Richard Hobbs, Michael Sheppard, Michael Gammage, 26 Sep 2006, In: Clinical Endocrinology. 91, p. 4809-4816 8 p.Research output: Contribution to journal › Article
- Published
Serum TSH concentration as a novel predictor of malignancy in thyroid nodules investigated by fine needle aspiration
Kristien Boelaert, Roger Holder, Michael Sheppard & Jayne Franklyn, 5 Sep 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4295-4301 7 p.Research output: Contribution to journal › Article
- Published
- Published
- Published
Growth hormone and its disorders
John Ayuk & Michael Sheppard, 1 Jan 2006, In: Postgraduate Medical Journal. 82, 963, p. 24-30 7 p.Research output: Contribution to journal › Review article
- Published
- 2005
- Published
Consensus statement: medical management of acromegaly
Michael Sheppard, 1 Dec 2005, In: European Journal of Endocrinology. 153(6), p. 737-740 4 p.Research output: Contribution to journal › Article
- Published
Thyroid function and mortality in patients treated for hyperthyroidism
Jayne Franklyn, Michael Sheppard, 6 Jul 2005, In: JAMA The Journal of the American Medical Association. 294, 1, p. 71-80 10 p.Research output: Contribution to journal › Article
- Published
Long-acting octreotide and prolonged-release lanreotide formulations have different pharmacokinetic profiles
Michael Sheppard, 1 Jul 2005, In: Journal of Clinical Pharmacology. 45(7), p. 836-844 9 p.Research output: Contribution to journal › Article
- Published
- Published
Association between serum TSH and free T4 concentrations and occurrence of atrial fibrillation in a large community-based population of elderly subjects. The Birmingham Elderly Thyroid Study
Michael Gammage, Jim Parle, Jayne Franklyn, Sue Wilson, Roger Holder, Michael Sheppard, Andrea Roalfe, 1 Jan 2005, p. OC34.Research output: Contribution to conference (unpublished) › Abstract
- Published
Association between serum thyrotrophin concentrations and occurrence of atrial fibrillation in a large community-based population of elderly subjects (the Birmingham Elderly Thyroid Study)
Lesley Roberts, Jim Parle, Jayne Franklyn, Sue Wilson, Roger Holder, Michael Sheppard, Richard Hobbs & Michael Gammage, 1 Jan 2005, p. A40-A40.Research output: Contribution to conference (unpublished) › Abstract
- Published
GH and mortality in acromegaly
Michael Sheppard, 1 Jan 2005, In: Journal of endocrinological investigation. 28(11), p. 75-77 3 p.Research output: Contribution to journal › Review article
- Published
The Birmingham Elderly Thyroid Study: TSH and fT4 values in 5784 community-living subjects aged 60 and over
Jim Parle, Jayne Franklyn, Sue Wilson, Roger Holder, Michael Sheppard, Richard Hobbs, Andrea Roalfe, Michael Gammage, 1 Jan 2005, p. P157.Research output: Contribution to conference (unpublished) › Abstract
- Published
The Skeletal System in Hyperthyroidism
Michael Sheppard & Neil Gittoes, 1 Jan 2005, The Thyroid, 9th edition. Vol. Ch 40.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Published
The Skeletal System in Hypothyroidism
Neil Gittoes & Michael Sheppard, 1 Jan 2005, The Thyroid, 9th edition. Vol. Ch 62.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Published
The critical parameters in GH excess
Michael Sheppard, 1 Jan 2005, In: Journal of endocrinological investigation. 28, 5 Suppl, p. 92-5 4 p.Research output: Contribution to journal › Review article
- 2004
- Published
- Published
The role of growth hormone-receptor antagonism in relation to acromegaly
John Ayuk & Michael Sheppard, 1 Nov 2004, In: Expert Opinion on Pharmacotherapy. 5(11), p. 2279-2285 7 p.Research output: Contribution to journal › Review article
- Published
Heart rate variability and turbulence in hyperthyroidism before, during, and after treatment
Faizel Osman, Jayne Franklyn, Saqib Chowdhary, Roger Holder, Michael Sheppard & Michael Gammage, 15 Aug 2004, In: The American Journal of Cardiology. 94, 4, p. 465-9 5 p.Research output: Contribution to journal › Article
- Published
Efficacy of Sandostatin LAR (long-acting somatostatin analogue) is similar in patients with untreated acromegaly and in those previously treated with surgery and/or radiotherapy
John Ayuk, Suzanne Stewart, Paul Stewart & Michael Sheppard, 1 Jan 2004, In: Clinical Endocrinology. 60(3), p. 375-381 7 p.Research output: Contribution to journal › Article
- Published
- Published
Growth hormone and pituitary radiotherapy, but not serum insulin-like growth factor-I concentrations, predict excess mortality in patients with acromegaly
John Ayuk, Michael Sheppard, Paul Stewart & Andrew Bates, 1 Jan 2004, In: Journal of Clinical Endocrinology and Metabolism. 89, 4, p. 1613-1617 5 p.Research output: Contribution to journal › Article
- Published
Growth hormone--from molecule to mortality
Michael Sheppard, 1 Jan 2004, In: Clinical Medicine. 4, 5, p. 437-40 4 p.Research output: Contribution to journal › Review article
- Published
- Published
- 2003
- Published
Pituitary tumour transforming gene and fibroblast growth factor 2 expression: potential prognostic indicators in differentiated thyroid cancer
Kristien Boelaert, Christopher McCabe, Lesley Tannahill, Neil Gittoes, Roger Holder, Jo Bradwell, Michael Sheppard & Jayne Franklyn, 1 May 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 5, p. 2341-2347 7 p.Research output: Contribution to journal › Article
- Published
Primary medical therapy for acromegaly.
Michael Sheppard, 1 Apr 2003, In: Clinical Endocrinology. 58, 4, p. 387-99 13 p.Research output: Contribution to journal › Article
- Published
Abnormal expression of 11beta-HSD type 2 in human pituitary adenomas: a prereceptor determinant of pituitary cell proliferation
Elizabeth Rabbitt, John Ayuk, Kristien Boelaert, Michael Sheppard, Martin Hewison, Paul Stewart & Neil Gittoes, 20 Mar 2003, In: Oncogene. 22(11), 11, p. 1663-1667 5 p.Research output: Contribution to journal › Article
- Published
Expression of pituitary tumour transforming gene (PTTG) and fibroblast growth factor-2 (FGF-2) in human pituitary adenomas: relationships to clinical tumour behaviour.
Christopher McCabe, Kristien Boelaert, Lesley Tannahill, Shakir Hussain, Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Feb 2003, In: Clinical Endocrinology. 58, 2, p. 141-50 10 p.Research output: Contribution to journal › Article
- Published