Michael Sheppard

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Publications

  1. Published

    A paradigm shift in the monitoring of patients with acromegaly: last available growth hormone may overestimate risk

    Mark Sherlock, Raoul Reulen, Aurora Aragon Alonso, John Ayuk, Michael Sheppard, Michael Hawkins, Andrew Bates & Paul Stewart, Feb 2014, In: The Journal of clinical endocrinology and metabolism. 99, 2, p. 478-85 8 p.

    Research output: Contribution to journal › Article › peer-review

  2. Published

    A potential role for human securin/PTTG in the developing fetal brain

    Kristien Boelaert, Christopher McCabe, Lesley Tannahill, Neil Gittoes, Michael Sheppard, Mark Kilby & Jayne Franklyn, 1 Jan 2003, p. P164.

    Research output: Contribution to conference (unpublished) › Abstract

  3. Published

    A randomized controlled trial of the effect of thyroxine replacement on cognitive function in community-living elderly subjects with subclinical hypothyroidism: the birmingham elderly thyroid study

    Jim Parle, Lesley Roberts, Sue Wilson, Andrea Roalfe, Sayeed Haque, Michael Sheppard, Jayne Franklyn & Richard Hobbs, 1 Aug 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 8, p. 3623-32 10 p.

    Research output: Contribution to journal › Article

  4. Published

    ACTH Deficiency, Higher Doses of Hydrocortisone Replacement, and Radiotherapy Are Independent Predictors of Mortality in Patients with Acromegaly

    Mark Sherlock, Raoul Reulen, Aurora Aragon Alonso, John Ayuk, Michael Sheppard, Michael Hawkins, Andrew Bates & Paul Stewart, 1 Nov 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 11, p. 4216-4223 8 p.

    Research output: Contribution to journal › Article

  5. Published

    Abnormal expression of 11beta-HSD type 2 in human pituitary adenomas: a prereceptor determinant of pituitary cell proliferation

    Elizabeth Rabbitt, John Ayuk, Kristien Boelaert, Michael Sheppard, Martin Hewison, Paul Stewart & Neil Gittoes, 20 Mar 2003, In: Oncogene. 22(11), 11, p. 1663-1667 5 p.

    Research output: Contribution to journal › Article

  6. Published

    An audit of management of differentiated thyroid cancer in specialist and non-specialist clinic settings

    Harish Kumar, Roger Holder, Michael Sheppard & Jayne Franklyn, 1 Jun 2001, In: Clinical Endocrinology. 54, 6, p. 719-723 5 p.

    Research output: Contribution to journal › Article

  7. Published

    Anaplastic carcinoma of the thyroid presenting with hyperthyroidism

    Michael Sheppard & Jayne Franklyn, 1 Jan 2002, p. P59.

    Research output: Contribution to conference (unpublished) › Abstract

  8. Published

    Angiotensin-converting enzyme (ACE)-inhibitor suppresses glomerular transforming growth factor-beta (TGF-beta) receptor expression in experimental diabetes in rats

    Ann Logan, Michael Sheppard, 6 Apr 2001, In: Diabetologia. 44, 4, p. 495-500 6 p.

    Research output: Contribution to journal › Article

  9. Published

    Association between premature mortality and hypopituitarism

    Jeremy Tomlinson, Robert Hills, Keith Wheatley, Andrew Bates, Michael Sheppard & Paul Stewart, 10 Feb 2001, In: Lancet. 357, 9254, p. 425-431 7 p.

    Research output: Contribution to journal › Article

  10. Published

    Association between serum TSH and free T4 concentrations and occurrence of atrial fibrillation in a large community-based population of elderly subjects. The Birmingham Elderly Thyroid Study

    Michael Gammage, Jim Parle, Jayne Franklyn, Sue Wilson, Roger Holder, Michael Sheppard, Andrea Roalfe, 1 Jan 2005, p. OC34.

    Research output: Contribution to conference (unpublished) › Abstract

  11. Published

    Association between serum free T4 concentration and atrial fibrillation

    Michael Gammage, Jim Parle, Roger Holder, Lesley Roberts, Richard Hobbs, Sue Wilson, Michael Sheppard & Jayne Franklyn, 14 May 2007, In: Archives of Internal Medicine. 167, 9, p. 928-934 7 p.

    Research output: Contribution to journal › Article

  12. Published

    Association between serum thyrotrophin concentrations and occurrence of atrial fibrillation in a large community-based population of elderly subjects (the Birmingham Elderly Thyroid Study)

    Lesley Roberts, Jim Parle, Jayne Franklyn, Sue Wilson, Roger Holder, Michael Sheppard, Richard Hobbs & Michael Gammage, 1 Jan 2005, p. A40-A40.

    Research output: Contribution to conference (unpublished) › Abstract

  13. Published

    Atrial fibrillation predicts mortality in hyperthyroidism

    Jayne Franklyn, Faizel Osman, Michael Sheppard & Michael Gammage, 1 Jan 2003.

    Research output: Contribution to conference (unpublished) › Abstract

  14. Published

    Atrial fibrillation predicts mortality in thyrotoxicosis

    Faizel Osman, Michael Sheppard & Michael Gammage, 1 Jan 2002, p. P275.

    Research output: Contribution to conference (unpublished) › Paper

  15. Published

    Atrial fibrillation predicts mortality in thyrotoxicosis

    Jayne Franklyn, Faizel Osman, Michael Sheppard & Michael Gammage, 1 Jan 2002, p. 102. 1 p.

    Research output: Contribution to conference (unpublished) › Paper

  16. Published

    Basic Fibroblast Growth Factor Is an Autocrine Factor for Rat Thyroid Follicular Cells

    Michael Sheppard, 1 Jan 1991, In: Annals of the New York Academy of Sciences. 638, 1, p. 453-455 3 p.

    Research output: Contribution to journal › Article › peer-review

  17. Published

    Cardiac autonomic function in hyperthyroidism

    Faizel Osman, Michael Sheppard, Michael Gammage & Jayne Franklyn, 1 Jan 2003, p. P263.

    Research output: Contribution to conference (unpublished) › Abstract

  18. Published

    Cardiac dysrhythmias and thyroid dysfunction: The hidden menace?

    Faizel Osman, Michael Gammage, Michael Sheppard & Jayne Franklyn, 1 Mar 2002, In: Journal of Clinical Endocrinology and Metabolism. 87, 3, p. 963-967 5 p.

    Research output: Contribution to journal › Review article

  19. Published

    Cardiac dysrhythmias in hyperthyroidism before and after antithyroid therapy

    Faizel Osman, Jayne Franklyn, Michael Sheppard & Michael Gammage, 1 Jan 2006, p. 215. 1 p.

    Research output: Contribution to conference (unpublished) › Abstract

  20. Published

    Cardiovascular manifestations of hyperthyroidism before and after antithyroid therapy; a matched case-control study

    Faizel Osman, Jayne Franklyn, Roger Holder, Michael Sheppard & Michael Gammage, 9 Jan 2007, In: Journal of the American College of Cardiology. 49, 1, p. 71-81 11 p.

    Research output: Contribution to journal › Article

  21. Published

    Clinical, quality of life, and economic value of acromegaly disease control

    Michael Sheppard, 1 Sep 2011, In: Pituitary. 14, 3, p. 284-294 11 p.

    Research output: Contribution to journal › Article

  22. Published

    Collection and storage conditions of serum for the analysis of thyroglobulin

    Michael Sheppard, 1 Jan 2002, p. pp36.

    Research output: Contribution to conference (unpublished) › Paper

  23. Published

    Consensus statement: medical management of acromegaly

    Michael Sheppard, 1 Dec 2005, In: European Journal of Endocrinology. 153(6), p. 737-740 4 p.

    Research output: Contribution to journal › Article

  24. Published

    Disruption of the SH3 domain of PTTG reveals distinct mechanisms of FGF-induction and cell transformation

    Kristien Boelaert, Lesley Tannahill, Jasbir Moore, Lawrence Young, Michael Sheppard, Jayne Franklyn, Neil Gittoes & Christopher McCabe, 1 Jan 2002.

    Research output: Contribution to conference (unpublished) › Abstract

  25. Published

    Does acromegaly enhance mortality?

    John Ayuk & Michael Sheppard, 1 Mar 2008, In: Reviews in endocrine & metabolic disorders. 9, 1, p. 33-9 7 p.

    Research output: Contribution to journal › Article

  26. Published

    Dysregulation of iodothyronine deiodinase enzyme expression and function in human pituitary tumours

    Lesley Tannahill, Christopher McCabe, Kachilele-Linjewile Kachilele, Kristien Boelaert, Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Jun 2002, In: Clinical Endocrinology. 56, 6, p. 735-743 9 p.

    Research output: Contribution to journal › Article

  27. Published

    Efficacy of Sandostatin LAR (long-acting somatostatin analogue) is similar in patients with untreated acromegaly and in those previously treated with surgery and/or radiotherapy

    John Ayuk, Suzanne Stewart, Paul Stewart & Michael Sheppard, 1 Jan 2004, In: Clinical Endocrinology. 60(3), p. 375-381 7 p.

    Research output: Contribution to journal › Article

  28. Published

    Evidence for the Use of IGF-I as a Predictor of Mortality in Acromegaly Is Lacking

    John Ayuk, Michael Sheppard, Andrew Bates & Paul Stewart, 1 Nov 2004, In: Journal of Clinical Endocrinology and Metabolism. 89, 11, p. 5867-5868 2 p.

    Research output: Contribution to journal › Article

  29. Published

    Expression and function of VEGF and its receptor KDR in pituitary tumors

    Christopher McCabe, Kristien Boelaert, Lesley Tannahill, Michael Sheppard, Neil Gittoes & Jayne Franklyn, 1 Jan 2002, p. P2-231.

    Research output: Contribution to conference (unpublished) › Paper

  30. Published

    Expression and function of VEGF and its receptor in pituitary tumours

    Christopher McCabe, Kristien Boelaert, Lesley Tannahill, Jattinder Khaira, Michael Sheppard, Neil Gittoes & Jayne Franklyn, 1 Jan 2002, p. OC14.

    Research output: Contribution to conference (unpublished) › Paper

  31. Published

    Expression of 11beta hydroxysteroid dehydrogenase isozyme mRNAs in normal pituitary and pituitary adenomas

    John Ayuk, Kristien Boelaert, Michael Sheppard, Martin Hewison, Paul Stewart & Neil Gittoes, 1 Jan 2001, p. OC17.

    Research output: Contribution to conference (unpublished) › Paper

  32. Published

    Expression of 11beta-hydroxysteroid dehydrogenase in rat osteoblastic cells: a functional role for intracrine regulation of glucocorticoid metabolism in bone

    Elizabeth Rabbitt, Rosemary Bland, Mark Cooper, Michael Sheppard, Paul Stewart & Martin Hewison, 1 Jun 2001, In: Journal of Cellular Biochemistry. 81, 3, p. 453-462 10 p.

    Research output: Contribution to journal › Article

  33. Published

    Expression of pituitary tumour transforming gene (PTTG) and fibroblast growth factor-2 (FGF-2) in human pituitary adenomas: relationships to clinical tumour behaviour.

    Christopher McCabe, Kristien Boelaert, Lesley Tannahill, Shakir Hussain, Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Feb 2003, In: Clinical Endocrinology. 58, 2, p. 141-50 10 p.

    Research output: Contribution to journal › Article

  34. Published

    GH and mortality in acromegaly

    Michael Sheppard, 1 Jan 2005, In: Journal of endocrinological investigation. 28(11), p. 75-77 3 p.

    Research output: Contribution to journal › Review article

  35. Published

    Gender, age, goitre type and sereum TSH predict thyroid neoplasia in 1500 patients with thyroid enlargement investigated by FNAC

    Kristien Boelaert, Michael Sheppard & Jayne Franklyn, 1 Jan 2004, p. OC21.

    Research output: Contribution to conference (unpublished) › Abstract

  36. Published

    Graves' disease complicated by multiple analytical interferences

    Michael Sheppard, 1 Jan 2002, p. pp18.

    Research output: Contribution to conference (unpublished) › Paper

  37. Published

    Growth hormone and its disorders

    John Ayuk & Michael Sheppard, 1 Jan 2006, In: Postgraduate Medical Journal. 82, 963, p. 24-30 7 p.

    Research output: Contribution to journal › Review article

  38. Published

    Growth hormone and pituitary radiotherapy, but not serum insulin-like growth factor-I concentrations, predict excess mortality in patients with acromegaly

    John Ayuk, Michael Sheppard, Paul Stewart & Andrew Bates, 1 Jan 2004, In: Journal of Clinical Endocrinology and Metabolism. 89, 4, p. 1613-1617 5 p.

    Research output: Contribution to journal › Article

  39. Published

    Growth hormone assay standardization: an important clinical advance.

    Michael Sheppard, 1 Feb 2007, In: Clinical Endocrinology. 66, 2, p. 157-61 5 p.

    Research output: Contribution to journal › Article

  40. Published

    Growth hormone therapy does not induce cancer

    Michael Sheppard, 1 Oct 2006, In: Nature clinical practice. Endocrinology & metabolism. 2, 10, p. 532-533 2 p.

    Research output: Contribution to journal › Article

  41. Published

    Growth hormone--from molecule to mortality

    Michael Sheppard, 1 Jan 2004, In: Clinical Medicine. 4, 5, p. 437-40 4 p.

    Research output: Contribution to journal › Review article

  42. Published

    Guidelines for the treatment of growth hormone excess and growth hormone deficiency in adults

    Michael Sheppard, 1 Sep 2008, In: Journal of endocrinological investigation. 31, 9, p. 820-838 19 p.

    Research output: Contribution to journal › Review article

  43. Published

    Heart rate variability and turbulence in hyperthyroidism

    Faizel Osman, Saqib Chowdhary, Michael Sheppard, Jayne Franklyn & Michael Gammage, 1 Jan 2003, p. 157. 1 p.

    Research output: Contribution to conference (unpublished) › Abstract

  44. Published

    Heart rate variability and turbulence in hyperthyroidism before, during, and after treatment

    Faizel Osman, Jayne Franklyn, Saqib Chowdhary, Roger Holder, Michael Sheppard & Michael Gammage, 15 Aug 2004, In: The American Journal of Cardiology. 94, 4, p. 465-9 5 p.

    Research output: Contribution to journal › Article

  45. Published

    Inhibition of 11beta-HSD2 has an anti-proliferative effect in human pituitary cells

    Elizabeth Rabbitt, Martin Hewison, Paul Stewart, Michael Sheppard & Neil Gittoes, 1 Jan 2002, p. P146.

    Research output: Contribution to conference (unpublished) › Paper

  46. Published

    Iodothyronine deiodinase enzyme mRNA expression in normal pituitary and pituitary adenomas

    Lesley Tannahill, Christopher McCabe, Kachilele-Linjewile Kachilele, Kristien Boelaert, Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Jan 2001.

    Research output: Contribution to conference (unpublished) › Paper

  47. Published

    Isolation and characterisation of human thyroid endothelial cells

    Ann Logan, Michael Sheppard, James Ramsden & Margaret Eggo, 1 Jan 2003, In: American Journal of Physiology: Endocrinology and Metabolism. 284(1), p. E168-E176

    Research output: Contribution to journal › Article

  48. Published

    Isolation and characterization of human thyroid endothelial cells

    Ann Logan, Michael Sheppard, James Ramsden & Margaret Eggo, Jan 2003, In: American Journal of Physiology Endocrinology and Metabolism. 284, 1, p. E168-76

    Research output: Contribution to journal › Article › peer-review

  49. Published

    Lack of association between serum TSH or free T4 and body mass index in euthyroid subjects

    Kristien Boelaert, Michael Sheppard, Roger Holder, Stephen Gough & Jayne Franklyn, 1 Feb 2006, In: Clinical Endocrinology. 64, 2, p. 125-128 4 p.

    Research output: Contribution to journal › Article

  50. Published

    Letter re: Monitoring the Response to Treatment in Acromegaly

    John Ayuk, Michael Sheppard, Andrew Bates & Paul Stewart, 10 May 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 8, p. 4980-4980 1 p.

    Research output: Contribution to journal › Letter

  51. Published

    Levothyroxine treatment and occurrence of fracture of the hip

    Michael Sheppard, Roger Holder & Jayne Franklyn, 11 Feb 2002, In: Archives of Internal Medicine. 162, 3, p. 338-343 6 p.

    Research output: Contribution to journal › Article

  52. Published

    Long-acting octreotide and prolonged-release lanreotide formulations have different pharmacokinetic profiles

    Michael Sheppard, 1 Jul 2005, In: Journal of Clinical Pharmacology. 45(7), p. 836-844 9 p.

    Research output: Contribution to journal › Article

  53. Published

    Long-term safety and efficacy of depot long-acting somatostatin analogs for the treatment of acromegaly

    John Ayuk, Paul Stewart & Michael Sheppard, 1 Sep 2002, In: Journal of Clinical Endocrinology and Metabolism. 87, 9, p. 4142-4146 5 p.

    Research output: Contribution to journal › Article

  54. Published

    Management of acromegaly in Latin America: expert panel recommendations

    Michael Sheppard, 1 Jun 2010, In: Pituitary. 13, 2, p. 168-175 8 p.

    Research output: Contribution to journal › Article

  55. Published

    Medical Therapy in Patients with Acromegaly: Predictors of Response and Comparison of Efficacy of Dopamine Agonists and Somatostatin Analogues

    Mark Sherlock, Aurora Aragon Alonso, Raoul Reulen, John Ayuk, Michael Sheppard, Andrew Bates & Paul Stewart, 1 Apr 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1255-1263 9 p.

    Research output: Contribution to journal › Article

  56. Published

    Medical therapy in acromegaly.

    Mark Sherlock & Michael Sheppard, 1 May 2011, In: Nature Reviews Endocrinology. 7, 5, p. 291-300 10 p.

    Research output: Contribution to journal › Article

  57. Published

    Modulation of 11beta-hydroxysteroid dehydrogenase by pro-inflammatory cytokines in osteoblasts: an autocrine switch from glucocorticoid inactivation to activation

    Mark Cooper, Iwona Bujalska, Elizabeth Rabbitt, Elizabeth Walker, Rosemary Bland, Michael Sheppard, Martin Hewison & Paul Stewart, 1 Jun 2001, In: Journal of Bone and Mineral Research. 16, 6, p. 1037-1044 8 p.

    Research output: Contribution to journal › Article

  58. Published

    Monitoring disease activity using growth hormone and insulin like growth factor-I in the follow up of 501 patients with acromegaly.

    Mark Sherlock, Aurora Aragon Alonso, Raoul Reulen, John Ayuk, Michael Sheppard, Andrew Bates & Paul Stewart, 27 Oct 2008, In: Clinical Endocrinology.

    Research output: Contribution to journal › Article

  59. Published

    Mortality in Patients with Pituitary Disease

    Mark Sherlock, John Ayuk, Jeremy Tomlinson, Andrew Toogood, Aurora Aragon Alonso, Michael Sheppard, Andrew Bates & Paul Stewart, 1 Jun 2010, In: Endocrine Reviews. 31, 3, p. 301-342 42 p.

    Research output: Contribution to journal › Review article

  60. Published

    Mortality in elderly patients with subclinical hyperthyroidism

    Jim Parle, Michael Sheppard & Jayne Franklyn, 2 Mar 2002, In: Lancet. 359, 9308, p. 799-799 1 p.

    Research output: Contribution to journal › Article

  61. Published

    NIS gene expression is a potential prognostic indicator for thyroid cancer and is inhibited by PTTG

    Kristien Boelaert, Lesley Tannahill, Margaret Eggo, Neil Gittoes, Michael Sheppard, Jayne Franklyn & Christopher McCabe, 1 Jan 2003, p. 28. 1 p.

    Research output: Contribution to conference (unpublished) › Abstract

  62. Published

    Outcome of atrial fibrillation complicating hyperthyroidism

    Faizel Osman, Michael Sheppard, Michael Gammage & Jayne Franklyn, 1 Jan 2004, p. P226.

    Research output: Contribution to conference (unpublished) › Abstract

  63. Published

    PTTG and FGF-2 -novel potential molecular indicators for thyroid cancer

    Kristien Boelaert, Christopher McCabe, Lesley Tannahill, Neil Gittoes, Michael Sheppard & Jayne Franklyn, 1 Jan 2002, p. OR 61-62.

    Research output: Contribution to conference (unpublished) › Paper

  64. Published

    Pituitary Disease

    Michael Sheppard & Paul Stewart, 1 Jan 2002, Kluwer Academic Publishers.

    Research output: Book/Report › Book

  65. Published

    Pituitary tumor transforming gene (PTTG) and thyroid disease

    Kristien Boelaert, Christopher McCabe, Jattinder Khaira, Neil Gittoes, Margaret Eggo, Michael Sheppard & Jayne Franklyn, 1 Jan 2001, p. 1-215. 215 p.

    Research output: Contribution to conference (unpublished) › Paper

  66. Published

    Pituitary tumor transforming gene (PTTG), PTTG binding factor (PBF) and related growth factor expression in sporadic pituitary tumours

    Christopher McCabe, Jattinder Khaira, Kristien Boelaert, Lesley Tannahill, Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Jan 2001, p. OC18.

    Research output: Contribution to conference (unpublished) › Abstract

  67. Published

    Pituitary tumour transforming gene and fibroblast growth factor 2 expression: potential prognostic indicators in differentiated thyroid cancer

    Kristien Boelaert, Christopher McCabe, Lesley Tannahill, Neil Gittoes, Roger Holder, Jo Bradwell, Michael Sheppard & Jayne Franklyn, 1 May 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 5, p. 2341-2347 7 p.

    Research output: Contribution to journal › Article

  68. Published

    Poor outcome of atrial fibrillation associated with hyperthyroidism

    Faizel Osman, Jayne Franklyn, Michael Sheppard & Michael Gammage, 1 Jan 2006, p. 214. 1 p.

    Research output: Contribution to conference (unpublished) › Abstract

  69. Published

    Prediction of all-cause and cardiovascular mortality in elderly people from one low serum thyrotropin result: a 10-year cohort study

    Jim Parle, Michael Sheppard & Jayne Franklyn, 15 Sep 2001, In: Lancet. 358, 9285, p. 861-865 5 p.

    Research output: Contribution to journal › Article

  70. Published

    Prediction of cure and risk of hypothyroidism in patients receiving 131I for hyperthyroidism.

    Kristien Boelaert, Michael Sheppard, Roger Holder, Stephen Gough & Jayne Franklyn, 1 Jan 2009, In: Clinical Endocrinology. 70, 1, p. 129-38 10 p.

    Research output: Contribution to journal › Article

  71. Published

    Premature mortality and hypopituitarism - Authors' reply

    Paul Stewart, Jeremy Tomlinson, Andrew Bates & Michael Sheppard, 1 Jun 2001, In: Lancet. 357, 9272, p. 1973-1974 2 p.

    Research output: Contribution to journal › Article

  72. Published

    Prevalence and outcome of atrial fibrillation in hyperthyroidism

    Faizel Osman, Saqib Chowdhary, Michael Sheppard, Michael Gammage & Jayne Franklyn, 1 Jan 2003, p. 188. 1 p.

    Research output: Contribution to conference (unpublished) › Abstract

  73. Published

    Prevalence of subclinical thyroid dysfunction and its relation to socioeconomic deprivation in the elderly: a community based cross-sectional survey

    Jim Parle, Lesley Roberts, Andrea Roalfe, Richard Hobbs, Michael Sheppard, Michael Gammage, 26 Sep 2006, In: Clinical Endocrinology. 91, p. 4809-4816 8 p.

    Research output: Contribution to journal › Article

  74. Published

    Primary medical therapy for acromegaly.

    Michael Sheppard, 1 Apr 2003, In: Clinical Endocrinology. 58, 4, p. 387-99 13 p.

    Research output: Contribution to journal › Article

  75. Published

    Quantitation of thyroglobulin (Tg) mRNA in peripheral blood of thyroid cancer patients

    Margaret Eggo, Michael Sheppard, Jayne Franklyn, 1 Jan 2001, p. 226. 1 p.

    Research output: Contribution to conference (unpublished) › Abstract

  76. Published

    Radioiodine treatment of hyperthyroidism - prognostic factors for outcome

    Amit Allahabadia, Michael Sheppard, Stephen Gough & Jayne Franklyn, 1 Aug 2001, In: Journal of Clinical Endocrinology and Metabolism. 86, 8, p. 3611-3617 7 p.

    Research output: Contribution to journal › Article

  77. Published

    Serum TSH concentration as a novel predictor of malignancy in thyroid nodules investigated by fine needle aspiration

    Kristien Boelaert, Roger Holder, Michael Sheppard & Jayne Franklyn, 5 Sep 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4295-4301 7 p.

    Research output: Contribution to journal › Article

  78. Published

    Simple clinical and biochemical parameters predict thyroid neoplasia and malignancy in 1500 patients investigated by FNAB

    Kristien Boelaert, Roger Holder, Michael Sheppard & Jayne Franklyn, 1 Jan 2004.

    Research output: Contribution to conference (unpublished) › Paper

  79. Published

    Sodium iodide gene expression is a potential prognostic indicator for thyroid cancer and is inhibited by PTTG

    Kristien Boelaert, Margaret Eggo, Neil Gittoes, Michael Sheppard, Jayne Franklyn & Christopher McCabe, 1 Jan 2003, p. OC37.

    Research output: Contribution to conference (unpublished) › Abstract

  80. Published

    Sodium iodide symporter (NIS) gene expression is a potential prognostic indicator for thyroid cancer and is inhibited by pituitary tumor transforming gene

    Kristien Boelaert, Lesley Tannahill, Margaret Eggo, Neil Gittoes, Michael Sheppard, Jayne Franklyn & Christopher McCabe, 1 Jan 2003.

    Research output: Contribution to conference (unpublished) › Paper

  81. Published

    Successful treatment of amiodarone-induced thyrotoxicosis

    Faizel Osman, Jayne Franklyn, Michael Sheppard & Michael Gammage, 1 Oct 2002, In: Circulation. 105, 11, p. 1275-1277 3 p.

    Research output: Contribution to journal › Article

  82. Published

    Switch in expression of 11beta-hydroxysteroid dehydrogenase (11beta-HSD) mRNAs in pituitary adenomas

    John Ayuk, Kristien Boelaert, Michael Sheppard, Martin Hewison, Paul Stewart & Neil Gittoes, 1 Jan 2001, p. OR34-1.

    Research output: Contribution to conference (unpublished) › Paper

  83. Published

    The Birmingham Elderly Thyroid Study: TSH and fT4 values in 5784 community-living subjects aged 60 and over

    Jim Parle, Jayne Franklyn, Sue Wilson, Roger Holder, Michael Sheppard, Richard Hobbs, Andrea Roalfe, Michael Gammage, 1 Jan 2005, p. P157.

    Research output: Contribution to conference (unpublished) › Abstract

  84. Published

    The DUTT1 gene, a novel NCAM family member is expressed in developing murine neural tissues and has an unusually broad pattern of expression

    Michael Sheppard, Jie Xiong, Farida Latif, 1 May 1998, In: Molecular and Cellular Neuroscience. 11, 1-2, p. 29-35 7 p.

    Research output: Contribution to journal › Article

  85. Published

    The Network for the Enhancement of Endocrinology and Oncology Knowledge: A case-based consideration of current practice in Cushing's disease and acromegaly

    Michael Sheppard, 1 Dec 2009, In: Best practice & research. Clinical endocrinology & metabolism. 23, p. S1-S4

    Research output: Contribution to journal › Article

  86. Published

    The SH3 domain of PTTG differentially mediates FGF-2 transactivation and cell transformation

    Kristien Boelaert, Lesley Tannahill, Jasbir Moore, Lawrence Young, Michael Sheppard, Neil Gittoes, Jayne Franklyn & Christopher McCabe, 1 Jan 2002, p. OR 40-42.

    Research output: Contribution to conference (unpublished) › Paper

  87. Published

    The Skeletal System in Hyperthyroidism

    Michael Sheppard & Neil Gittoes, 1 Jan 2005, The Thyroid, 9th edition. Vol. Ch 40.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  88. Published

    The Skeletal System in Hypothyroidism

    Neil Gittoes & Michael Sheppard, 1 Jan 2005, The Thyroid, 9th edition. Vol. Ch 62.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  89. Published

    The assessment of thyroid neoplasia

    Kristien Boelaert, Jayne Franklyn, Michael Sheppard, 1 Jan 2007, Clinical Endocrine Oncology.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  90. Published

    The critical parameters in GH excess

    Michael Sheppard, 1 Jan 2005, In: Journal of endocrinological investigation. 28, 5 Suppl, p. 92-5 4 p.

    Research output: Contribution to journal › Review article

  91. Published

    The destruction box PTTG mediates cell transformation

    Christopher McCabe, Lesley Tannahill, Kristien Boelaert, Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Jan 2002, p. P139.

    Research output: Contribution to conference (unpublished) › Paper

  92. Published

    The destruction box of pituitary tumor transforming gene (PTTG) mediates cell transformation in vitro

    Christopher McCabe, Jattinder Khaira, Kristien Boelaert, Lesley Tannahill, Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Jan 2001, p. OR37-2.

    Research output: Contribution to conference (unpublished) › Paper

  93. Published

    The interleukin-1 receptor antagonist gene shows no allelic association with three autoimmune diseases

    Amit Allahabadia, Caroline Gordon, Michael Sheppard, Jayne Franklyn, Jun 1999, In: Thyroid. 9, 6, p. 627-8 2 p.

    Research output: Contribution to journal › Article › peer-review

  94. Published

    The role of growth hormone-receptor antagonism in relation to acromegaly

    John Ayuk & Michael Sheppard, 1 Nov 2004, In: Expert Opinion on Pharmacotherapy. 5(11), p. 2279-2285 7 p.

    Research output: Contribution to journal › Review article

  95. Published

    Thyroid Function Tests

    Neil Gittoes, Jayne Franklyn, Michael Sheppard, 1 Jan 2001, Endocrinology (4th Edition). Vol. 2 Ch 97.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  96. Published

    Thyroid function and mortality in patients treated for hyperthyroidism

    Jayne Franklyn, Michael Sheppard, 6 Jul 2005, In: JAMA The Journal of the American Medical Association. 294, 1, p. 71-80 10 p.

    Research output: Contribution to journal › Article

  97. Published

    Thyroid-stimulating hormone rapidly stimulates inositol polyphosphate formation in FRTL-5 thyrocytes without activating phosphoinositidase C

    Philip Hunt, Margaret Eggo, Michael Sheppard, Chris Kirk & Bob Michell, 15 May 1996, In: Biochemical Journal. 316, 1, p. 175-182 8 p.

    Research output: Contribution to journal › Article › peer-review

  98. Published

    Tie-2 is expressed on thyroid follicular cells, is increased in goiter, and is regulated by thryotropin through cyclic adenosine 3',5'-monophosphate

    James Ramsden, Helen Cocks, Munjiba Shams, Michael Sheppard, Asif Ahmed & Margaret Eggo, 1 Jun 2001, In: Journal of Clinical Endocrinology and Metabolism. 86, 6, p. 2709-2716 8 p.

    Research output: Contribution to journal › Article

  99. Published

    Using an increased fixed dose of 1311 (600MBq) leads to improved outcome in patients with hyperthyroidism

    Kristien Boelaert, Michael Sheppard, Stephen Gough & Jayne Franklyn, 1 Jan 2007, p. P312.

    Research output: Contribution to conference (unpublished) › Abstract

  100. Published

    Vascular endothelial growth factor, its receptor KDR/Flk-1, and pituitary tumor transforming gene in pituitary tumors

    Christopher McCabe, Kristien Boelaert, Lesley Tannahill, Jattinder Khaira, Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Sep 2002, In: Journal of Clinical Endocrinology and Metabolism. 87, 9, p. 4238-4244 7 p.

    Research output: Contribution to journal › Article

  101. Published

    Weight gain following treatment of hyperthyroidism

    Roger Holder, Michael Sheppard & Jayne Franklyn, 1 Aug 2001, In: Clinical Endocrinology. 55, 2, p. 233-239 7 p.

    Research output: Contribution to journal › Article