Melanie Madhani

ORCID: 0000-0001-8596-763X

Colleges, School and Institutes

Willingness to take PhD students

Yes

PhD projects

Dr Madhani is interested in supervising doctoral research on mechanisms underlying cardioprotection following myocardial ischaemia reperfusion injury.

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Most downloaded publications

Cardiac metabolism - a promising therapeutic target for heart failure
Michael Frenneaux & Melanie Madhani, 2017, In: Pharmacology & Therapeutics.

Research output: Contribution to journal › Article › peer-review

133 downloads
Pharmacology and therapeutic role of inorganic nitrite and nitrate in vasodilatation
Michael Frenneaux & Melanie Madhani, 1 Dec 2014, In: Pharmacology & Therapeutics. 144, 3, p. 303-320 18 p.

Research output: Contribution to journal › Article › peer-review

128 downloads
Development of Fluorinated Analogues of Perhexiline with Improved Pharmacokinetic Properties and Retained Efficacy
Melanie Madhani, 13 Apr 2017, In: Journal of Medicinal Chemistry. 60, 7, p. 2780-2789

Research output: Contribution to journal › Article › peer-review

104 downloads
A robust and versatile mass spectrometry platform for comprehensive assessment of the thiol redox metabolome
Melanie Madhani, , , & , 1 Jun 2018, In: Redox Biology. 16, p. 359-380

Research output: Contribution to journal › Article › peer-review

100 downloads
Role of aldehyde dehydrogenase in hypoxic vasodilator effects of nitrite in rats and humans
Alessandra Borgognone, , , , Nigel Drury, , , , , , , & Melanie Madhani, 12 Jun 2015, In: British Journal of Pharmacology. 172, 13, p. 3341-3352 12 p.

Research output: Contribution to journal › Article › peer-review

97 downloads

Recent publications

Nitrite and myocardial ischaemia reperfusion injury. Where are we now?
Kayleigh Griffiths, , Michael Frenneaux, & Melanie Madhani, Jul 2021, In: Pharmacology & Therapeutics. 223, 107819.

Research output: Contribution to journal › Article › peer-review

Bilateral Remote Ischaemic Conditioning in Children (BRICC) trial: protocol for a two-centre, double-blind, randomised controlled trial in young children undergoing cardiac surgery
Nigel Drury, , Rebecca Woolley, , , , , Warwick Dunn, Melanie Madhani, , Paulus Kirchhof & , 7 Oct 2020, In: BMJ open. 10, 10, e042176.

Research output: Contribution to journal › Article › peer-review

Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling
Kayleigh Griffiths, , , , , , , , Alessandra Borgognone, , , & Melanie Madhani, 1 Jan 2020, In: Cardiovascular Research. 116, 1, p. 51-62 12 p.

Research output: Contribution to journal › Article › peer-review

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