Lorraine Harper

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Publications

  1. 2021
  2. E-pub ahead of print

    Anti-tumour necrosis factor treatment for the prevention of ischaemic events in patients with deficiency of adenosine deaminase 2 (DADA2)

    Lorraine Harper, 9 Jan 2021, In: Rheumatology.

    Research output: Contribution to journal › Article › peer-review

  3. 2020
  4. Accepted/In press

    Management of fatigue with physical activity and behavioural change support in vasculitis: a feasibility study

    Lorraine Harper, Catherine Moakes, Ian Litchfield, Matthew Morgan, Sheila Greenfield, Natalie Rowland, Sue Jowett & Amanda Daley, 24 Nov 2020, (Accepted/In press) In: Rheumatology.

    Research output: Contribution to journal › Article › peer-review

  5. Accepted/In press

    Cardiovascular and renal morbidity in Takayasu arteritis: a population-based retrospective cohort study from UK

    Rasiah Thayakaran, Nicola Adderley, Krishnarajah Nirantharakumar & Lorraine Harper, 28 Aug 2020, (Accepted/In press) In: Arthritis and Rheumatology.

    Research output: Contribution to journal › Article › peer-review

  6. Accepted/In press

    Rituximab as therapy to induce remission after relapse in ANCA-associated vasculitis

    Lorraine Harper, Apr 2020, (Accepted/In press) In: Annals of the Rheumatic Diseases.

    Research output: Contribution to journal › Article › peer-review

  7. Published

    Plasma exchange and glucocorticoids in severe ANCA-associated vasculitis

    Lorraine Harper, Samir Mehta & Natalie Rowland, 13 Feb 2020, In: The New England Journal of Medicine. 382, 7, p. 622-631 10 p.

    Research output: Contribution to journal › Article › peer-review

  8. 2019
  9. Published

    Glucocorticoid induced adrenal insufficiency is common in steroid treated glomerular diseases - proposed strategy for screening and management

    Kristien Boelaert & Lorraine Harper, 6 May 2019, In: BMC Nephrology. 20, 1, 154.

    Research output: Contribution to journal › Article › peer-review

  10. Published

    Mycophenolate mofetil versus cyclophosphamide for remission induction in ANCA-associated vasculitis: a randomised, non-inferiority trial

    Lorraine Harper, Mar 2019, In: Annals of the Rheumatic Diseases. 78, 3, p. 399-405

    Research output: Contribution to journal › Article › peer-review

  11. Published

    Cardiovascular, thromboembolic and renal outcomes in IgA vasculitis (Henoch-Schönlein purpura): a retrospective cohort study using routinely collected primary care data

    Anuradhaa Subramanian, Nicola Adderley, Lorraine Harper & Krishnarajah Nirantharakumar, Feb 2019, In: Annals of the Rheumatic Diseases. 78, 2, p. 261-269 9 p.

    Research output: Contribution to journal › Article › peer-review

  12. 2018
  13. Published

    Treatment of fatigue with physical activity and behavioural change support in Vasculitis – study protocol for an open-label randomised controlled feasibility study

    Lorraine Harper, Dimitri Chanouzas, Sheila Greenfield, Catherine Moakes, Natalie Rowland, Sue Jowett & Amanda Daley, Dec 2018, In: BMJ open. 8, 10, e023769.

    Research output: Contribution to journal › Article › peer-review

  14. Published

    The host cellular immune response to cytomegalovirus targets the endothelium and is associated with increased arterial stiffness in ANCA-associated vasculitis

    Dimitri Chanouzas, Michael Sagmeister, Matthew Morgan, Paul Moss & Lorraine Harper, 29 Aug 2018, In: Arthritis Research & Therapy. 20, 1, p. 194 194.

    Research output: Contribution to journal › Article › peer-review

  15. Published

    Subclinical reactivation of cytomegalovirus drives CD4+CD28null T-cell expansion and impaired immune response to pneumococcal vaccination in ANCA-associated vasculitis

    Dimitri Chanouzas, Michael Sagmeister, Sian Faustini, Alex Richter, Matthew Morgan, Paul Moss & Lorraine Harper, 9 Aug 2018, In: The Journal of Infectious Diseases. jiy498.

    Research output: Contribution to journal › Article › peer-review

  16. E-pub ahead of print

    Outcomes and compliance with standards of care in ANCA-associated vasculitis: insights from a large multi-region audit

    CM McGrath, Lorraine Harper, 31 Jul 2018, In: Rheumatology Advances in Practice.

    Research output: Contribution to journal › Article › peer-review

  17. Published

    Humoral immunity to memory antigens and pathogens is maintained in patients with chronic kidney disease

    Sian Faustini, Marisol Perez-Toledo, Matthew Morgan, Alex Richter, Paul Moss, Ian Henderson, Lorraine Harper & Adam Cunningham, 16 Apr 2018, In: PLoS ONE. 13, 4, e0195730.

    Research output: Contribution to journal › Article › peer-review

  18. Published

    How does the outcome of research training fellowships funded via the NHS compare with that from competitively funded fellowships from the MRC and other charities: a cross-sectional retrospective survey of trainees undertaking research training in the West Midlands

    Matthew Morgan & Lorraine Harper, 1 Jan 2018, In: BMJ open. 8, 1, e019630.

    Research output: Contribution to journal › Article › peer-review

  19. 2017
  20. Published

    Avoidance of Harm From Treatment for ANCA-Associated Vasculitis

    Lorraine Harper, Dec 2017, In: Current Treatment Options in Rheumatology. 3, 4, p. 230-243 14 p.

    Research output: Contribution to journal › Review article › peer-review

  21. Published

    The European Vasculitis Society 2016 Meeting Report

    Lorraine Harper, Mark Little, Nov 2017, In: Kidney International Reports. 2, 6, p. 1018-1031

    Research output: Contribution to journal › Article › peer-review

  22. Published

    Randomized trial of C5a receptor inhibitor avacopan in ANCA-associated vasculitis

    Lorraine Harper, Sep 2017, In: Journal of the American Society of Nephrology. 28, 9, p. 2756-2767 12 p.

    Research output: Contribution to journal › Article › peer-review

  23. Published

    Genetic variation at the CD28 locus and its impact on expansion of pro-inflammatory CD28 negative T cells in healthy individuals

    Evaggelia Liaskou, Louisa Jeffery, Lorraine Harper & Gideon Hirschfield, 9 Aug 2017, In: Scientific Reports. 7, 1, p. 7652

    Research output: Contribution to journal › Article › peer-review

  24. Published

    Negative anti-neutrophil cytoplasm antibody at switch to maintenance therapy is associated with a reduced risk of relapse

    Matthew Morgan, Lorraine Harper, 7 Jun 2017, In: Arthritis Research & Therapy. 19, 1, p. 129

    Research output: Contribution to journal › Article › peer-review

  25. 2016
  26. Published

    Physical Fatigue, Fitness and Muscle Function in Patients with Anti-neutrophil Cytoplasm Antibody-Associated Vasculitis.

    Matthew Morgan & Lorraine Harper, 1 Sep 2016, In: Arthritis Care & Research. 68, 9, p. 1332-1339

    Research output: Contribution to journal › Article › peer-review

  27. Published

    Analysis of single nucleotide polymorphisms implicate mTOR signalling in the development of new-onset diabetes after transplantation

    Lorraine Harper, Jun 2016, In: Biochimica et Biophysica Acta. Clinical. 5, p. 41-45 5 p.

    Research output: Contribution to journal › Article › peer-review

  28. Published

    Association of Low B Cell Count and IgG Levels With Infection, and Poor Vaccine Response With All-Cause Mortality in an Immunosuppressed Vasculitis Population

    Matthew Morgan, Alex Richter, Mark Drayson & Lorraine Harper, Jun 2016, In: Arthritis Care & Research. 68, 6, p. 853-60 8 p.

    Research output: Contribution to journal › Article › peer-review

  29. E-pub ahead of print

    Deficiency of adenosine deaminase type 2 (DADA2): A description of phenotype and genotype in 15 cases

    Lorraine Harper, 5 Apr 2016, In: Arthritis & Rheumatology (Hoboken).

    Research output: Contribution to journal › Article › peer-review

  30. Published

    The Dutch Transplantation in Vasculitis (DUTRAVAS) Study: Outcome of Renal Transplantation in Antineutrophil Cytoplasmic Antibody-associated Glomerulonephritis

    Lorraine Harper, Apr 2016, In: Transplantation.

    Research output: Contribution to journal › Article › peer-review

  31. 2015
  32. Published

    Treatment of severe renal disease in ANCA positive and negative small vessel vasculitis with rituximab

    Matthew Morgan, Lorraine Harper, Jul 2015, In: American Journal of Nephrology. 41, 4-5, p. 296-301 6 p.

    Research output: Contribution to journal › Article › peer-review

  33. Published

    Comparability of patients with ANCA-associated vasculitis enrolled in clinical trials or in observational cohorts

    Lorraine Harper & 10 others, Caroline Savage, 29 May 2015, In: Clinical and Experimental Rheumatology. 33, 2 Suppl 89, p. S-77-83

    Research output: Contribution to journal › Article › peer-review

  34. Published

    Rituximab for treatment of severe renal disease in ANCA associated vasculitis

    Matthew Morgan, Lorraine Harper, 19 May 2015, In: Journal of nephrology.

    Research output: Contribution to journal › Article › peer-review

  35. Published

    Transitional B lymphocytes are associated with protection from kidney allograft rejection: a prospective study

    John Girdlestone, Dennis Briggs, Lorraine Harper, May 2015, In: American Journal of Transplantation. 15, 5, p. 1384-91 8 p.

    Research output: Contribution to journal › Article › peer-review

  36. Published

    Skewed Fc glycosylation profiles of anti-proteinase 3 immunoglobulin G1 autoantibodies from granulomatosis with polyangiitis patients show low levels of bisection, galactosylation, and sialylation

    Lorraine Harper, Caroline Savage & Matthew Morgan, 3 Apr 2015, In: Journal of Proteome Research. 14, 4, p. 1657-65 9 p.

    Research output: Contribution to journal › Article › peer-review

  37. Published

    Getting the balance right: adverse events of therapy in anti-neutrophil cytoplasm antibody vasculitis

    Lorraine Harper & Mark Little, Apr 2015, In: Nephrology, Dialysis, Transplantation. 30 , Suppl 1, p. i164-i170 7 p.

    Research output: Contribution to journal › Article › peer-review

  38. Published

    Successful outcome of pregnancy in patients with anti-neutrophil cytoplasm antibody-associated small vessel vasculitis

    Adam Croft, Stuart Smith, Lorraine Harper & Matthew Morgan, Apr 2015, In: Kidney International. 87, 4, p. 807-11 5 p.

    Research output: Contribution to journal › Article › peer-review

  39. Published

    Glucocorticoid treatment and damage in the anti-neutrophil cytoplasm antibody-associated vasculitides: long-term data from the European Vasculitis Study Group trials

    Lorraine Harper, Mar 2015, In: Rheumatology (Oxford). 54, 3, p. 471-81 11 p.

    Research output: Contribution to journal › Article › peer-review

  40. Published

    CD4+CD28- T-cell expansions in ANCA-associated vasculitis and association with arterial stiffness: baseline data from a randomised controlled trial

    Dimitri Chanouzas, Paul Moss, Matthew Morgan & Lorraine Harper, 26 Feb 2015, In: The Lancet. 385 Suppl 1, p. S30

    Research output: Contribution to journal › Article › peer-review

  41. Published

    Endothelial nitric oxide synthase single nucleotide polymorphism and left ventricular function in early chronic kidney disease

    Colin Chue, Nicky Edwards, Matthew Simmonds, Stephen Gough, Lorraine Harper, Jon Townend, 22 Jan 2015, In: PLoS ONE. 10, 1, e0116160.

    Research output: Contribution to journal › Article › peer-review

  42. Published

    Damage in the anca-associated vasculitides: long-term data from the European vasculitis study group (EUVAS) therapeutic trials

    Lorraine Harper, Jan 2015, In: Annals of the Rheumatic Diseases. 74, 1, p. 177-84 8 p.

    Research output: Contribution to journal › Article › peer-review

  43. 2014
  44. Published

    BSR and BHPR guideline for the management of adults with ANCA-associated vasculitis

    David Carruthers, Lorraine Harper, Dec 2014, In: Rheumatology (Oxford). 53, 12, p. 2306-2309 4 p.

    Research output: Contribution to journal › Article

  45. Published

    Genetics of toll like receptor 9 in ANCA associated vasculitides

    Lorraine Harper, 1 May 2014, In: Annals of the Rheumatic Diseases. 73, 5, p. 890-896 7 p.

    Research output: Contribution to journal › Article › peer-review

  46. Published

    Markers for work disability in anti-neutrophil cytoplasmic antibody-associated vasculitis

    Lorraine Harper, Mark Little, May 2014, In: Rheumatology (Oxford). 53, 5, p. 953-6 4 p.

    Research output: Contribution to journal › Article › peer-review

  47. Published

    The SEM6A6 locus is not associated with granulomatosis with polyangiitis or other forms of antineutrophil cytoplasmic antibody-associated vasculitides in Europeans: comment on the article by Xie et al

    Julia Holle, Lorraine Harper, May 2014, In: Arthritis & Rheumatology (Hoboken). 66, 5, p. 1400-1401 2 p.

    Research output: Contribution to journal › Letter

  48. Published

    The characterisation and determinants of quality of life in ANCA associated vasculitis

    Lorraine Harper, Mark Little, Jan 2014, In: Annals of the Rheumatic Diseases. 73, 1, p. 207-11 5 p.

    Research output: Contribution to journal › Article › peer-review

  49. Published

    Podocytes regulate neutrophil recruitment by glomerular endothelial cells via IL-6–mediated crosstalk

    Sahithi Kuravi, Helen McGettrick, Lorraine Harper, Ed Rainger & Caroline Savage, 2014, In: Journal of Immunology.

    Research output: Contribution to journal › Article › peer-review

  50. 2013
  51. Published

    Predictors and consequences of fatigue in prevalent kidney transplant recipients

    Jos Bosch, David Jones, Nicholas Inston, Philip McTernan, Lorraine Harper, 15 Dec 2013, In: Transplantation. 96, 11, p. 987-994 8 p.

    Research output: Contribution to journal › Article › peer-review

  52. Published

    Impaired direct priming of CD8 T cells by donor-derived cytomegalovirus following kidney transplantation

    Annette Pachnio, Gemma Banham, Helen Smith, Lorraine Harper, Paul Moss, 1 Oct 2013, In: Journal of the American Society of Nephrology. 24, 10, p. 1698-1708 11 p.

    Research output: Contribution to journal › Article › peer-review

  53. Published

    Explaining fatigue in ANCA-associated vasculitis

    Lorraine Harper, Sep 2013, In: Rheumatology (Oxford). 52, 9, p. 1680-5 6 p.

    Research output: Contribution to journal › Article › peer-review

  54. Published

    Cardiovascular Effects of Sevelamer in Stage 3 CKD

    Colin Chue, Jon Townend, William Moody, Lorraine Harper, Nicky Edwards, Apr 2013, In: Journal of the American Society of Nephrology. 24, 5, p. 842-52 11 p.

    Research output: Contribution to journal › Article › peer-review

  55. Published

    L42. Morbidity in patients with ANCA-associated vasculitis

    Lorraine Harper, Apr 2013, In: La Presse Medicale. 42, 4 Pt 2, p. 612-6 5 p.

    Research output: Contribution to journal › Article

  56. Published

    Validity of glycated haemoglobin to diagnose new onset diabetes after transplantation

    Lorraine Harper, Mar 2013, In: Transplant international : official journal of the European Society for Organ Transplantation. 26, 3, p. 315-21 7 p.

    Research output: Contribution to journal › Article › peer-review

  57. Published

    Caveolin-1 single nucleotide polymorphism in antineutrophil cytoplasmic antibody associated vasculitis

    Julia Holle, Stuart Smith, Lavanya Kamesh, Peter Hewins, Lorraine Harper, 2013, In: PLoS ONE. 8, 7, p. e69022

    Research output: Contribution to journal › Article › peer-review

  58. Published

    Cytomegalovirus seropositivity is associated with increased arterial stiffness in patients with chronic kidney disease

    Colin Chue, Nicky Edwards, Tanya Pankhurst, Lorraine Harper, Sarah Lauder, Jon Townend, Paul Moss, 2013, In: PLoS ONE. 8, 2, p. e55686

    Research output: Contribution to journal › Article › peer-review

  59. 2012
  60. Published

    Neutrophil serine proteases mediate inflammatory cell recruitment by glomerular endothelium and progression towards dysfunction

    Sahithi Kuravi, Lorraine Harper, Julie Williams, Ed Rainger, Caroline Savage & Samantha Tull, Dec 2012, In: Nephrology, Dialysis, Transplantation. 27, 12, p. 4331-8 8 p.

    Research output: Contribution to journal › Article › peer-review

  61. Published

    Complications of long-term therapy for ANCA-associated systemic vasculitis

    Lorraine Harper, Sep 2012, In: Nature Reviews. Nephrology. 8, 9, p. 523-32 10 p.

    Research output: Contribution to journal › Article

  62. Published

    PR3 and elastase alter PAR1 signaling and trigger vWF release via a calcium-independent mechanism from glomerular endothelial cells

    Samantha Tull, Sahithi Kuravi, Bahjat Al-Ani, Stephen Young, Lorraine Harper, Julie Williams, Ed Rainger & Caroline Savage, 29 Aug 2012, In: PLoS ONE. 7, 8, p. e43916

    Research output: Contribution to journal › Article › peer-review

  63. Published

    Genetically distinct subsets within ANCA-associated vasculitis

    Julia Holle, Lorraine Harper, Mark Little & 17 others, , Caroline Savage, 19 Jul 2012, In: The New England Journal of Medicine. 367, 3, p. 214-23 10 p.

    Research output: Contribution to journal › Article › peer-review

  64. Published

    Elevated active secretory sphingomyelinase in antineutrophil cytoplasmic antibody-associated primary systemic vasculitis.

    Matthew Morgan, Mark Little, Lorraine Harper, Paul Bacon & Stephen Young, 4 Jan 2012, In: Annals of the Rheumatic Diseases. 71, 6, p. 1100-1102

    Research output: Contribution to journal › Article › peer-review

  65. 2011
  66. Published

    ANCA-stimulated neutrophils release BLyS and promote B cell survival: a clinically relevant cellular process.

    Neil Holden, Julie Williams, Matthew Morgan, John Gordon, Lorraine Harper & Caroline Savage, 1 Dec 2011, In: Annals of the Rheumatic Diseases. 70, 12, p. 2229-33 5 p.

    Research output: Contribution to journal › Article

  67. Published

    Pulse versus daily oral cyclophosphamide for induction of remission in ANCA-associated vasculitis: long-term follow-up.

    Lorraine Harper, Matthew Morgan, Caroline Savage, 29 Nov 2011, In: Annals of the Rheumatic Diseases. 71, p. 955-960

    Research output: Contribution to journal › Article

  68. Published

    Neutrophil chemotaxis in granulomatosis with polyangiitis (Wegener's) and idiopathic pulmonary fibrosis.

    Alex Richter, Gavin Perkins, Elizabeth Sapey, Lorraine Harper & David Thickett, 1 Nov 2011, In: The European respiratory journal. 38, 5, p. 1081-8 8 p.

    Research output: Contribution to journal › Article

  69. Published

    A dual role for diacylglycerol kinase generated phosphatidic acid in auto-antibody induced neutrophil exocytosis

    Neil Holden, Caroline Savage, Stephen Young, Mike Wakelam, Lorraine Harper & Julie Williams, Nov 2011, In: Molecular Medicine. 17, 11-12, p. 1242-1252 11 p.

    Research output: Contribution to journal › Article › peer-review

  70. Published

    ANCA-associated vasculitis is linked to carriage of the Z allele of alpha(1) antitrypsin and its polymers

    Matthew Morgan, Alice Turner, Stuart Smith, Julie Williams, Caroline Savage & Lorraine Harper, 1 Oct 2011, In: Annals of the Rheumatic Diseases. 70, 10, p. 1851-1856 6 p.

    Research output: Contribution to journal › Article

  71. Published

    Incidence of malignancy in patients treated for antineutrophil cytoplasm antibody-associated vasculitis: follow-up data from European Vasculitis Study Group clinical trials

    Lorraine Harper, 1 Aug 2011, In: Annals of the Rheumatic Diseases. 70, 8, p. 1415-1421 7 p.

    Research output: Contribution to journal › Article

  72. Published

    Long- term outcome of paediatric patients with ANCA vasculitis

    Stuart Smith, Lorraine Harper, 1 Jun 2011, In: Pediatric Rheumatology. 9, p. 12 1 p.

    Research output: Contribution to journal › Article

  73. Published

    Recommendations for the use of rituximab in anti-neutrophil cytoplasm antibody-associated vasculitis.

    Lorraine Harper, Caroline Savage, 25 May 2011, In: Rheumatology.

    Research output: Contribution to journal › Article

  74. Published

    A Model to Predict Cardiovascular Events in Patients With Newly Diagnosed Wegener's Granulomatosis and Microscopic Polyangiitis

    Lorraine Harper, 1 Apr 2011, In: Arthritis Care & Research. 63, 4, p. 588-596 9 p.

    Research output: Contribution to journal › Article

  75. Published

    Are there specific genetic risk factors for the different forms of ANCA-associated vasculitis?

    Lorraine Harper, 1 Apr 2011, In: Annals of the Rheumatic Diseases. 70, 4, p. 707-U197

    Research output: Contribution to journal › Article

  76. Published

    Plasma Exchange for Severe ANCA-Associated Vasculitis?

    Lorraine Harper & Matthew Morgan, 1 Apr 2011, In: American Journal of Kidney Diseases. 57, 4, p. 532-5 4 p.

    Research output: Contribution to journal › Article

  77. Published

    CD4+CD28- T-cell expansion in Wegener's granulomatosis is driven by latent CMV and is associated with an increased risk of infection and mortality.

    Matthew Morgan, Annette Pachnio, Desley Neil, Caroline Savage, Paul Moss & Lorraine Harper, 24 Mar 2011, In: Arthritis & Rheumatism. 63, 7, p. 2127-2137 11 p.

    Research output: Contribution to journal › Article

  78. Published

    Long-term patient survival in ANCA-associated vasculitis

    Lorraine Harper, 1 Mar 2011, In: Annals of the Rheumatic Diseases. 70, 3, p. 488-494 7 p.

    Research output: Contribution to journal › Article

  79. Published

    Addition of Infliximab to Standard Therapy for ANCA-Associated Vasculitis

    Matthew Morgan, Mark Drayson, Caroline Savage & Lorraine Harper, 1 Jan 2011, In: Nephron. Clinical Practice. 117, 2, p. C89-C97

    Research output: Contribution to journal › Article

  80. 2010
  81. Published

    Mycophenolate Mofetil vs Azathioprine for Remission Maintenance in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis A Randomized Controlled Trial

    Caroline Savage, Lorraine Harper, 1 Dec 2010, In: JAMA The Journal of the American Medical Association. 304, 21, p. 2381-2388 8 p.

    Research output: Contribution to journal › Article

  82. Published

    Does immunosuppressant medication lower blood pressure and arterial stiffness in patients with chronic kidney disease? An observational study.

    Nicky Edwards, Colin Hutchison, Caroline Savage, Jon Townend & Lorraine Harper, 21 Oct 2010, In: Hypertension Research.

    Research output: Contribution to journal › Article

  83. Published

    Contrasting association of a non-synonymous leptin receptor gene polymorphism with Wegener's granulomatosis and Churg-Strauss syndrome

    Lorraine Harper, 1 May 2010, In: Rheumatology. 49, 5, p. 907-914 8 p.

    Research output: Contribution to journal › Article

  84. Published

    ANCA-associated vasculitides-lessons from the adult literature.

    Joannis Vamvakopoulos, Caroline Savage & Lorraine Harper, 1 Apr 2010, In: Pediatric Nephrology.

    Research output: Contribution to journal › Article

  85. Published

    An increased risk of ischemic heart disease in Wegener's granulomatosis: Comment on the article by Faurschou et al.

    Matthew Morgan & Lorraine Harper, 1 Feb 2010, In: Arthritis & Rheumatism. 62, 2, p. 637-8 2 p.

    Research output: Contribution to journal › Article

  86. Published

    Patients with Wegener's granulomatosis demonstrate a relative deficiency and functional impairment of T-regulatory cells.

    Matthew Morgan, Karen Piper, Lorraine Harper, Paul Moss & Caroline Savage, 27 Jan 2010, In: Immunology.

    Research output: Contribution to journal › Article

  87. Published

    Recent advances to achieve remission induction in antineutrophil cytoplasmic antibody-associated vasculitis

    Lorraine Harper, 1 Jan 2010, In: Current Opinion in Rheumatology. 22, 1, p. 37-42 6 p.

    Research output: Contribution to journal › Review article

  88. 2009
  89. Published

    CT60 and +49 polymorphisms of CTLA 4 are associated with ANCA-positive small vessel vasculitis

    Julie Williams, Stephen Gough, Caroline Savage & Lorraine Harper, 1 Dec 2009, In: Rheumatology. 48, 12, p. 1502-5 4 p.

    Research output: Contribution to journal › Article

  90. Published

    Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis

    Julie Williams, Lorraine Harper, 1 Dec 2009, In: BMC Medical Genetics. 10, 121.

    Research output: Contribution to journal › Article › peer-review

  91. Published

    Increased incidence of cardiovascular events in patients with antineutrophil cytoplasmic antibody-associated vasculitides: A matched-pair cohort study

    Matthew Morgan, Peter Nightingale, Caroline Savage & Lorraine Harper, 1 Nov 2009, In: Arthritis & Rheumatism. 60, 11, p. 3493-500 8 p.

    Research output: Contribution to journal › Article

  92. Published

    Renal transplantation in systemic vasculitis: when is it safe?

    Mark Little, Steve Jacques & Lorraine Harper, 1 Oct 2009, In: Nephrology, Dialysis, Transplantation. 24, 10, p. 3219-3225 7 p.

    Research output: Contribution to journal › Article

  93. Published

    Novel association of the CD226 (DNAM-1) Gly307Ser polymorphism in Wegener's granulomatosis and confirmation for multiple sclerosis in German patients

    Lorraine Harper, 1 Sep 2009, In: Genes and Immunity. 10, 6, p. 591-595 5 p.

    Research output: Contribution to journal › Article

  94. Published

    Early mortality in systemic vasculitis: relative contribution of adverse events and active vasculitis

    Mark Little, Peter Nightingale, Caroline Savage & Lorraine Harper, 1 Jul 2009, In: Annals of the Rheumatic Diseases. 69, 6, p. 1036-1043 8 p.

    Research output: Contribution to journal › Article

  95. Published

    Adverse effects of therapy for ANCA-associated vasculitis.

    Lorraine Harper, 1 Jun 2009, In: Best Practice & Research: Clinical Rheumatology. 23, 3, p. 391-401 11 p.

    Research output: Contribution to journal › Article

  96. Published

    Pulse versus daily oral cyclophosphamide for induction of remission in antineutrophil cytoplasmic antibody-associated vasculitis: a randomized trial

    Lorraine Harper & Caroline Savage, 19 May 2009, In: Annals of internal medicine. 150, 10, p. 670-80 11 p.

    Research output: Contribution to journal › Article

  97. Published

    ANCA-associated vasculitis: from bench research to novel treatments

    Lalit Pallan, Caroline Savage & Lorraine Harper, 1 May 2009, In: Nature Reviews Microbiology. 5, 5, p. 278-86 9 p.

    Research output: Contribution to journal › Review article

  98. Published

    Pulmonary infection in Wegener's granulomatosis and Idiopathic pulmonary fibrosis.

    Alex Richter, Lorraine Harper & David Thickett, 8 Apr 2009, In: Thorax. 64, 8, p. 692-697 6 p.

    Research output: Contribution to journal › Article

  99. Published

    Soluble endostatin is a novel inhibitor of epithelial repair in idiopathic pulmonary fibrosis.

    Alex Richter, Lorraine Harper & David Thickett, 1 Feb 2009, In: Thorax. 64, 2, p. 156-61 6 p.

    Research output: Contribution to journal › Article

  100. Published

    Vasculitic IgA nephropathy: prognosis and outcome.

    Tanya Pankhurst, Peter Nightingale & Lorraine Harper, 1 Jan 2009, In: Nephron. Clinical Practice. 112, 1, p. c16-24

    Research output: Contribution to journal › Article

  101. 2007
  102. Published

    Recurrences and Infections During Continuous Immunosuppressive Therapy After Beginning Dialysis in ANCA-Associated Vasculitis

    Clara Day, Peter Hewins, Caroline Savage & Lorraine Harper, 1 Jul 2007, In: American Journal of Kidney Diseases. 50, 1, p. 36-46 11 p.

    Research output: Contribution to journal › Article

  103. Published

    FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity

    Lorraine Harper, Lavanya Kamesh, Heward King, Stephen Gough, 1 Jun 2007, In: Nature Genetics. 39, 6, p. 721-723 3 p.

    Research output: Contribution to journal › Article

  104. Published

    ANCA-associated vasculitis: new�options beyond steroids and cytotoxic drugs

    Caroline Savage & Lorraine Harper, 1 May 2007, In: Expert opinion on investigational drugs. 16, 5, p. 689-703 15 p.

    Research output: Contribution to journal › Article

  105. 2006
  106. Published

    Plasmapheresis in nephrology: an update

    Lorraine Harper, Nov 2006, In: Current Opinion in Nephrology and Hypertension. 15, 6, p. 603-9 7 p.

    Research output: Contribution to journal › Article

  107. Published

    Anti-neutrophil cytoplasm-associated glomerulonephritis.

    Matthew Morgan, Lorraine Harper, Julie Williams & Caroline Savage, 1 May 2006, In: Journal of the American Society of Nephrology. 17, 5, p. 1224-34 11 p.

    Research output: Contribution to journal › Article

  108. Published

    ANCA-associated vasculitis: is there a role for neutrophil apoptosis in autoimmunity?

    Lorraine Harper, Mar 2006, In: Expert Review of Clinical Immunology. 2, 2, p. 237-44 8 p.

    Research output: Contribution to journal › Article

  109. Published

    IL-18 is upregulated in the kidney and primes neutrophil responsiveness in ANCA-associated vasculitis

    Peter Hewins, Matthew Morgan, Neil Holden, Desley Neil, Julie Williams, Caroline Savage & Lorraine Harper, 1 Feb 2006, In: Kidney International. 69, 3, p. 605-615 11 p.

    Research output: Contribution to journal › Article

  110. 2005
  111. Published

    Pulmonary manifestations of anti-neutrophil cytoplasmic antibody (ANCA)-positive vasculitis

    David Thickett, Alex Richter, Nazim Nathani, Gavin Perkins & Lorraine Harper, 30 Nov 2005, In: Rheumatology. 45, 3, p. 261-8 8 p.

    Research output: Contribution to journal › Article

  112. Published

    Effect of verocytotoxins (Shiga-like toxins) on human neutrophils in vitro

    Julia Holle, Julie Williams, Lorraine Harper & Caroline Savage, 1 Sep 2005, In: Pediatric Nephrology. 20, 9, p. 1237-1244 8 p.

    Research output: Contribution to journal › Article

  113. Published

    Translational research in autoimmunity: aims of therapy in vasculitis

    Lorraine Harper, Caroline Savage, 1 May 2005, In: Rheumatology. 44, 5, p. 573-576 4 p.

    Research output: Contribution to journal › Editorial

  114. Published

    Can neutrophils be manipulated in vivo?

    Matthew Morgan, Lorraine Harper, Xiaomei Lu, Gerard Nash, Julie Williams & Caroline Savage, May 2005, In: Rheumatology. 44, 5, p. 597-601 5 p.

    Research output: Contribution to journal › Review article

  115. Published

    Anti-endothelial cell antibodies from lupus patients bind to apoptotic endothelia cellspromoting macrophage phagocytosis but do not induce apoptosis

    Julie Williams, Rachel Colman, Caroline Savage & Lorraine Harper, 1 Mar 2005, In: Rheumatology. 44, p. 879-84 6 p.

    Research output: Contribution to journal › Article

  116. Published

    Impairment of lung function, health status and functional capacity in patients with ANCA-associated vasculitis

    Caroline Savage & Lorraine Harper, 22 Feb 2005, In: Rheumatology. 44, p. 623-8 6 p.

    Research output: Contribution to journal › Article

  117. Published

    ANCA-associated renal vasculitis at the end of the twentieth century - a disease of older patients

    Lorraine Harper & Caroline Savage, 3 Feb 2005, In: Rheumatology. 44, p. 495-501 7 p.

    Research output: Contribution to journal › Article

  118. 2004
  119. Published

    Malignancy is increased in ANCA-associated vasculitis

    Tanya Pankhurst, Caroline Savage, Caroline Gordon & Lorraine Harper, Dec 2004, In: Rheumatology. 43, 12, p. 1532-5 4 p.

    Research output: Contribution to journal › Article › peer-review

  120. Published

    The importance of resolution of inflammation in pathogenesiss of ANCA-associated vasculitis

    Lorraine Harper, Julie Williams & Caroline Savage, 1 Jun 2004, In: Biochemical Society Transactions. 32, p. 502-6 5 p.

    Research output: Contribution to journal › Review article

  121. Published

    Primary small vessel vasculitis

    Lorraine Harper, 1 Jan 2004, Horizons in Medicine.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  122. Published

    Propylthiouracil and carbimazole associated -antineutrophil cytoplasmic antibodies (ANCA) in patients with Graves' disease

    Lorraine Harper, Heward King, Stephen Gough, Caroline Savage & Jayne Franklyn, 1 Jan 2004, In: Clinical Endocrinology. 60, p. 671-5 5 p.

    Research output: Contribution to journal › Article

  123. Published

    Prospective study of TNFalpha blockade with infliximab in ANCA-associated systemic vasculitis

    Lorraine Harper, Paul Bacon, Caroline Savage, 1 Jan 2004, In: Journal of the American Society of Nephrology. 15, p. 717-21 5 p.

    Research output: Contribution to journal › Article

  124. 2003
  125. Published

    Dendritic cell uptake of human apoptotic and necrotic neutrophils inhibits CD40, CD80, and CD86 expression and reduces allogeneic T cell responses: relevance to systemic vasculitis

    Lorraine Harper, Mark Drayson & Caroline Savage, 1 Aug 2003, In: Arthritis & Rheumatism. 48, 8, p. 2362-2374 13 p.

    Research output: Contribution to journal › Article

  126. Published

    High prevalence of ANCA in patients with Graves' disease treated with thionamides

    Lorraine Harper, Amit Allahabadia, Heward King, Stephen Gough, Caroline Savage & Jayne Franklyn, 1 Jan 2003, p. P274.

    Research output: Contribution to conference (unpublished) › Abstract

  127. 2002
  128. Published

    ANCA-positive vasculitis

    Lavanya Kamesh, Lorraine Harper & Caroline Savage, 1 Jul 2002, In: Journal of the American Society of Nephrology. 13, 7, p. 1953-1960 8 p.

    Research output: Contribution to journal › Review article

  129. Published

    Hypogalactosylation of serum IgG in patients with ANCA-associated systemic vasculitis

    Anne Ben-smith, Lorraine Harper, Caroline Savage & Roy Jefferis, 1 Jul 2002, In: Clinical & Experimental Immunology. 129, 1, p. 183-190 8 p.

    Research output: Contribution to journal › Article

  130. Published

    Adjuvant treatment of patients with antineutrophil cytoplasmic antibody-associated vasculitis with vitamins E and C reduces superoxide production by neutrophils

    Lorraine Harper, Sarah Nuttall, Una Martin & Caroline Savage, 1 Mar 2002, In: Rheumatology. 41, 3, p. 274-278 5 p.

    Research output: Contribution to journal › Article

  131. Published

    Leukocyte-endothelial interactions in antineutrophil cytoplasmic antibody-associated systemic vasculitis

    Lorraine Harper & Caroline Savage, 1 Jan 2002, In: Rheumatic Diseases Clinics of North America. 27, p. 887-903 17 p.

    Research output: Contribution to journal › Review article

  132. Published

    New findings in pathogenesis of antineutrophil cytoplasm antibody-associated vasculitis

    Caroline Savage, Lorraine Harper, 1 Jan 2002, In: Current Opinion in Rheumatology. 14, p. 15-22 8 p.

    Research output: Contribution to journal › Review article

  133. Published

    Predictors of exercise capacity in patients with pulmonary manifestations of primary small cessel vasculitis

    Clare Newall, Lorraine Harper, Caroline Savage, 1 Jan 2002, p. 290s.

    Research output: Contribution to conference (unpublished) › Paper

  134. Published

    Respiratory muscle function, exercise tolerance and health status in patients with primary small vessel vasculitis

    Clare Newall, Lorraine Harper, Caroline Savage, 1 Jan 2002, p. 196s.

    Research output: Contribution to conference (unpublished) › Paper

  135. 2001
  136. Published

    Neutrophil priming and apoptosis in anti-neutrophil cytoplasmic autoantibody-associated vasculitis

    Lorraine Harper, Paul Cockwell & Caroline Savage, 1 May 2001, In: Kidney International. 59, 5, p. 1729-1738 10 p.

    Research output: Contribution to journal › Article

  137. Published

    IgG from MPO-ANCA positive patients stimulates greater activation of primed neutrophils than IgG from PR3-ANCA positive patients

    Lorraine Harper, David Radford, Mark Drayson & Caroline Savage, 1 Apr 2001, In: Arthritis & Rheumatism. 44, p. 921-30 10 p.

    Research output: Contribution to journal › Article

  138. 2000
  139. Published

    ABC of arterial and vascular disease: vasculitis

    Caroline Savage, Lorraine Harper & Alexander Howie, 13 May 2000, In: BMJ. 320, 7245, p. 1325-8 4 p.

    Research output: Contribution to journal › Article

  140. Published

    Pathogenesis of ANCA-associated systemic vasculitis

    Lorraine Harper & Caroline Savage, Feb 2000, In: Journal of Pathology. 190, 3, p. 349-59 11 p.

    Research output: Contribution to journal › Article

  141. Published

    Anti-neutrophil cytoplasmic antibodies induce reactive oxygen-dependent dysregulation of primed neutrophil apoptosis and clearance by macrophages

    Lorraine Harper, Jimi Adu & Caroline Savage, 1 Jan 2000, In: American Journal of Physiology. 157, p. 211-220 10 p.

    Research output: Contribution to journal › Article

  142. Published

    Treatment of vasculitic IgA nephropathy

    Lorraine Harper, Alexander Howie, Caroline Savage & Jimi Adu, 1 Jan 2000, In: Journal of nephrology. 13, 5, p. 360-6 7 p.

    Research output: Contribution to journal › Article

  143. 1999
  144. Published

    Treatment of IgA nephropathy

    Caroline Savage & Lorraine Harper, 13 Mar 1999, In: The Lancet. 353, 9156, p. 860-2 3 p.

    Research output: Contribution to journal › Article

  145. 1998
  146. Published

    Artherogenic low-density lipoprotein sub-fraction profiles in dialysis and transplanted patients

    Lorraine Harper, Martin Kendall, 1 Jan 1998, In: Nephrology, Dialysis, Transplantation. 13, p. 2281-2287 7 p.

    Research output: Contribution to journal › Article

  147. Published

    Case of propylthiouracil induced ANCA associated small vessel vasculitis

    Lorraine Harper & Caroline Savage, 1 Jan 1998, In: Nephrol Dial Transplant. 13, p. 455-458 4 p.

    Research output: Contribution to journal › Article

  148. Published

    Unusual complication of central line insertion

    Lorraine Harper, 1 Jan 1998, In: British Journal of Radiology. 71, p. 457-458 2 p.

    Research output: Contribution to journal › Article

  149. 1997
  150. Published

    Glomerulonephritis and non-Hodgkin lymphoma

    Lorraine Harper, Jul 1997, In: Nephrology, Dialysis, Transplantation. 12, 7, p. 1520-5 6 p.

    Research output: Contribution to journal › Article › peer-review

  151. Published

    Primary systemic vasculitis

    Caroline Savage & Lorraine Harper, 22 Feb 1997, In: The Lancet. 349, 9051, p. 553-8 6 p.

    Research output: Contribution to journal › Article

  152. Published

    Focal segmental necrotizing glomerulonephritis in rheumatoid arthritis

    Lorraine Harper, Alexander Howie, Caroline Savage, 1 Feb 1997, In: QJM. 90, 2, p. 125-132 8 p.

    Research output: Contribution to journal › Article

  153. Published

    Serum C-reactive protein as a marker for infection and inflammation in regular dialysis patients

    Lorraine Harper, 1 Jan 1997, In: Clinical Nephrology. 48, p. 371-374 4 p.

    Research output: Contribution to journal › Article

  154. 1996
  155. Published

    Mechanisms of acute renal failure

    Chris Lote, Lorraine Harper & Caroline Savage, Jul 1996, In: British Journal of Anaesthesia. 77, 1, p. 82-9 8 p.

    Research output: Contribution to journal › Article

  156. 1995
  157. Published

    Prostate-specific antigen levels in patients receiving long-term dialysis

    Lorraine Harper, 1 Oct 1995, In: British journal of urology. 76, 4, p. 482-3 2 p.

    Research output: Contribution to journal › Article