Lee Middleton
Research Projects
Calcium Supplementation for Prevention of Pre-eclampsia in High Risk Women: CaPE Trial
Lee Middleton, Andrew Ewer, Patrick Moore & Peter Brocklehurst
NIHR
1/09/20 → 1/02/25
Project: Other Government Departments
Early detection and treatment of post-partum hemorrhage using the MOTIVE bundle : a World Health Organization cluster randomized trial with health economic analysis (the E-MOTIVE study)
Adam Devall, Karla Hemming, Tracy Roberts, Lee Middleton, Peter Brocklehurst, Arri Coomarasamy, Ioannis Gallos & James Martin
THE BILL & MELINDA GATES FOUNDATION
1/11/19 → 1/01/23
Project: Research
Letrozole for improving fertility in women with polycystic ovary syndrome
Tracy Roberts, Wiebke Arlt, Lee Middleton, Arri Coomarasamy, Ioannis Gallos, Adam Devall & Rima Smith
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/04/19 → 28/02/23
Project: Other Government Departments
Rescue Cervical Cerclage to prevent miscarriage and preterm birth a Randomised Controlled Trial (C-STICH2)
Peter Brocklehurst, Victoria Ann Morton, Lee Middleton, Arri Coomarasamy, R. Katie Morris & Laura Jones
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/07/18 → 30/06/25
Project: Other Government Departments
A Randomised Controlled Trial to investigate the clinical and cost-effectiveness of Paravertebral Blockade compared with Thoracic Epidural Blockade in reducing Chronic Post-Thoractomy Pain (TOPIC 2)
Louise Jackson, Babu Naidu, Fang Gao Smith, & Lee Middleton
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/05/18 → 31/10/22
Project: Other Government Departments
A randomised controlled trial of a Sythetic Osmotic cervical dilator for induction of Labour in comparison to dinoprostone Vaginal insErt (SOLVE)
MEDICEM INTERNATIONAL CR
1/06/17 → 31/05/19
Project: EU
Vaginal Preparation at caesarean section to Reduce Endometriosis and Prevent Sepsis (PREPS)
Victoria Ann Morton, R. Katie Morris, David Lissauer & Lee Middleton
NIHR CENTRAL COMMISSIONING FACILITY
1/06/17 → 31/08/18
Project: Other Government Departments
A randomised trial of mifepristone and misoprostol alone in the medical management of missed miscarriage: The MIFEMISO Trial
Adam Devall, Lee Middleton, Arri Coomarasamy, Tracy Roberts & Laura Jones
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/02/17 → 31/07/20
Project: Other Government Departments
GEM3: A multi-centre double-blind placebo-controlled randomised trial of a combination of methotrexate and gefitinib versus methotrexate alone as a treatment for ectopic pregnancy
Lee Middleton & Arri Coomarasamy
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/04/16 → 30/09/19
Project: Other Government Departments
High Or Low Dose Syntocinon for delay in labour (HOLDS)
Andrew Ewer, Lee Middleton, Sara Kenyon & Beck Taylor
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/03/16 → 31/05/19
Project: Other Government Departments
GaPP2:A multi-centre randomised controlled trial of the efficacy and mechanism of action of gabapentin for the management of chronic pelvic pain in women
NIHR
1/09/15 → 31/10/19
Project: Other Government Departments
Local Oestrogen Treatment in postmenopausal women Undergoing pelvic organ prolapse Surgery (LOTUS) - Feasibility Study
NIHR
1/04/15 → 31/08/17
Project: Other Government Departments
A randomised controlled trial to investigate the effectiveness of thoracic eqidural and paravertebral blockade in reducing chronic post-thoracotomy pian -TOPIC pilot study
Fang Gao Smith, Babu Naidu, Lee Middleton, , Jane Daniels & Joyce Yeung
NIHR CENTRAL COMMISSIONING FACILITY
1/12/14 → 30/11/16
Project: Other Government Departments
C-STICH: Cerclage Suture Type for Incompetent Cervix and effect on Health outcomes
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/12/14 → 31/08/21
Project: Other Government Departments
Effectiveness of progesterone to prevent miscarriage in women with early pregnancy bleeding: A placebo-controlled randomised trial (PRISM Study: Progesterone In Spontaneous Miscarriage)
Tracy Roberts, Adam Devall, Arri Coomarasamy & Lee Middleton
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/10/14 → 14/10/18
Project: Other Government Departments
Ulipristal acetate versus conventional management of heavy menstrual bleeding (HMB including uterine fibroids): a randomised controlled trial and exploration of mechanism of action (UCON trial)
NIHR
1/10/14 → 31/05/21
Project: Other Government Departments
Preventing Recurrence of Endometriosis by Means of long acting Protestogen Therapy (Pre-empt)
Lee Middleton, Tracy Roberts &
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/12/13 → 30/04/23
Project: Other Government Departments
Effectiveness of Antibiotic Prophylaxis During Surgical Evacuation of the Uterus for Miscarriage Management in Low Income Countries (AIMS Trial)
Arri Coomarasamy, David Lissauer & Lee Middleton
MEDICAL RESEARCH COUNCIL
10/06/13 → 9/08/17
Project: Research Councils
The Relationship Between Refluxing Pelvic Veins and Chronic Pelvic Pain in Women
Jane Daniels, Janesh Gupta, Rita Solanki & Lee Middleton
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/08/12 → 31/07/14
Project: Other Government Departments
Anti Epileptic drug monitoring in Pregnancy: an evaluation of effectiveness, cost effectiveness and acceptability of monitoring strategies
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/10/11 → 30/09/15
Project: Other Government Departments