Projects per year
Search results
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Active
Digital multi-component intervention to IMPROVE the care of older people living with Diabetes and chronic Kidney Disease: a type 2 hybrid effectiveness-implementation cluster randomised trial in primary care (Short title: IMPROVE DKD Trial)
Jowett, S., Thomas, N., Mehta, S., Shukla, D., Crowe, F., Middleton, L., Nirantharakumar, K., Tearne, S. & Greaves, C.
1/04/24 → 31/03/28
Project: Other Government Departments
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NIHR Birmingham Keele Warwick RSS
Miller, R., Thomas, N., Rowland, N., Mathers, J., Williams, I., Middleton, L., Roberts, T., Deeks, J., Calvert, M., Al-Janabi, H., Riley, R., Morris, K., Nirantharakumar, K., Hemming, K., Moore, D., Blackburn, S., Sitch, A. & Takwoingi, Y.
1/10/23 → 30/09/28
Project: Other Government Departments
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Exploring the feasibility and acceptability of conducting a study comparing the effectiveness of colpocleisis with sacrospinous fixation in women with pelvic organ prolapse (the C-POP study)
Jones, L., Jackson, L. & Middleton, L.
1/04/23 → 31/12/24
Project: Other Government Departments
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Cefalexin for UTIs - Right treatment Length in Young children: the CURLY trial
Oppong, R., McNally, A., Ottridge, R., Morris, K., Marriott, J., Middleton, L. & Woolley, R.
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/09/22 → 28/02/25
Project: Other Government Departments
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Calcium Supplementation for Prevention of Pre-eclampsia in High Risk Women: CaPE Trial
Middleton, L., Ewer, A., Brocklehurst, P. & Jackson, L.
1/11/20 → 30/04/25
Project: Other Government Departments
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Laparoscopic versus abdominal hysterectomy trial (LAVA)
McKinnon, W., Middleton, L., Roberts, T., Brocklehurst, P., Jones, L. & Woolley, R.
1/07/20 → 30/06/27
Project: Other Government Departments
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Early detection and treatment of post-partum hemorrhage using the MOTIVE bundle : a World Health Organization cluster randomized trial with health economic analysis (the E-MOTIVE study)
Devall, A., Hemming, K., Roberts, T., Middleton, L., Brocklehurst, P., Coomarasamy, A., Martin, J., Gallos, I., Morris, K. & Price, M.
The Bill & Melinda Gates Foundation
1/11/19 → 30/06/25
Project: Research
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Letrozole for improving fertility in women with polycystic ovary syndrome
Roberts, T., Arlt, W., Middleton, L., Coomarasamy, A., Devall, A., Smith, R., Thangaratinam, S. & Gough, R.
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/04/19 → 31/08/25
Project: Other Government Departments
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Induction: High or Low Dose Syntocinon? iHOLDS
Ewer, A., Middleton, L., Kenyon, S., Jackson, L. & Brocklehurst, P.
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/03/19 → 28/02/25
Project: Other Government Departments
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Rescue Cervical Cerclage to prevent miscarriage and preterm birth a Randomised Controlled Trial (C-STICH2)
Brocklehurst, P., Morton, V., Middleton, L., Coomarasamy, A., Morris, K., Jones, L., Thangaratinam, S. & Moakes, C.
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/07/18 → 30/04/26
Project: Other Government Departments
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A Randomised Controlled Trial to investigate the clinical and cost-effectiveness of Paravertebral Blockade compared with Thoracic Epidural Blockade in reducing Chronic Post-Thoractomy Pain (TOPIC 2)
Jackson, L., Naidu, B., Gao Smith, F., Jarrett, H. & Middleton, L.
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/05/18 → 30/04/24
Project: Other Government Departments
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Preventing Recurrence of Endometriosis by Means of long acting Protestogen Therapy (Pre-empt) - OPEN FOR DISSEMINATION ONLY
Middleton, L., Roberts, T. & Gough, R.
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/12/13 → 30/04/25
Project: Other Government Departments
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Finished
Prehospital Point of Care Testing to Enable Decision-making (PrePoCTED)
1/03/23 → 29/02/24
Project: Other Government Departments
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Vaginal Preparation at caesarean section to Reduce Endometriosis and Prevent Sepsis (PREPS)
Morton, V., Morris, K., Lissauer, D. & Middleton, L.
NIHR CENTRAL COMMISSIONING FACILITY
1/06/17 → 31/08/18
Project: Other Government Departments
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A randomised trial of mifepristone and misoprostol alone in the medical management of missed miscarriage: The MIFEMISO Trial
Devall, A., Middleton, L., Coomarasamy, A., Roberts, T., Jones, L. & Gough, R.
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/02/17 → 31/03/24
Project: Other Government Departments
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GEM3: A multi-centre double-blind placebo-controlled randomised trial of a combination of methotrexate and gefitinib versus methotrexate alone as a treatment for ectopic pregnancy
Middleton, L. & Coomarasamy, A.
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/04/16 → 30/09/19
Project: Other Government Departments
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High Or Low Dose Syntocinon for delay in labour (HOLDS)
Ewer, A., Middleton, L. & Kenyon, S.
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/03/16 → 31/05/19
Project: Other Government Departments
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GaPP2:A multi-centre randomised controlled trial of the efficacy and mechanism of action of gabapentin for the management of chronic pelvic pain in women
Middleton, L. & Gough, R.
1/09/15 → 31/10/19
Project: Other Government Departments
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Local Oestrogen Treatment in postmenopausal women Undergoing pelvic organ prolapse Surgery (LOTUS) - Feasibility Study
Middleton, L. & Gough, R.
1/04/15 → 31/08/17
Project: Other Government Departments
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C-STICH: Cerclage Suture Type for Incompetent Cervix and effect on Health outcomes
Middleton, L., Ewer, A. & Gough, R.
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/12/14 → 31/10/21
Project: Other Government Departments
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A randomised controlled trial to investigate the effectiveness of thoracic eqidural and paravertebral blockade in reducing chronic post-thoracotomy pian -TOPIC pilot study
Gao Smith, F., Naidu, B., Middleton, L., Combes, G., Daniels, J. & Yeung, J.
NIHR CENTRAL COMMISSIONING FACILITY
1/12/14 → 30/11/16
Project: Other Government Departments
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Ulipristal acetate versus conventional management of heavy menstrual bleeding (HMB including uterine fibroids): a randomised controlled trial and exploration of mechanism of action (UCON trial)
1/10/14 → 31/05/21
Project: Other Government Departments
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Effectiveness of progesterone to prevent miscarriage in women with early pregnancy bleeding: A placebo-controlled randomised trial (PRISM Study: Progesterone In Spontaneous Miscarriage)
Roberts, T., Devall, A., Coomarasamy, A. & Middleton, L.
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/10/14 → 14/10/18
Project: Other Government Departments
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Effectiveness of Antibiotic Prophylaxis During Surgical Evacuation of the Uterus for Miscarriage Management in Low Income Countries (AIMS Trial)
Coomarasamy, A., Lissauer, D. & Middleton, L.
10/06/13 → 9/08/17
Project: Research Councils
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The Relationship Between Refluxing Pelvic Veins and Chronic Pelvic Pain in Women
Daniels, J., Gupta, J., Solanki, R. & Middleton, L.
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/08/12 → 31/07/14
Project: Other Government Departments
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Anti Epileptic drug monitoring in Pregnancy: an evaluation of effectiveness, cost effectiveness and acceptability of monitoring strategies
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/10/11 → 30/09/15
Project: Other Government Departments
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MEDAL - Can magnetic resonance imaging (MRI) scan replace or triage the use of laparoscopy in establishing a diagnosis among women presenting in secondary care with chronic pelvic pain (CPP)
Daniels, J., Deeks, J., Middleton, L. & Roberts, T.
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/10/11 → 30/11/15
Project: Other Government Departments
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Efficacy and Mechanism of Thyroxine Treatment on Pregnancy and Neonatal Outcomes in Women with Thyroid Antibodies: A Randomised, Placebo-Controlled, Double-Blind, Multi-Centre Trial
Kilby, M., Middleton, L., Coomarasamy, A. & Boelaert, K.
1/06/11 → 31/03/18
Project: Other Government Departments
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NIHR HTA - A Randomised Trial of Treating Fibroids with either Embolisation or Myomectomy to Measure the Effect on Quality of Life Among Women Wishing to Avoid Hysterectomy (FEMME)
Middleton, L. & Gough, R.
NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE
1/06/11 → 31/12/19
Project: Other Government Departments
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The PLUTO Trial: Percutaneous Shunting in Lower Urinary Tract Obstruction
Kilby, M., Morris, K., Daniels, J., Khan, K., Middleton, L., Bryan, S., Roberts, T., Taylor, C., Gray, R., Lilford, R. & Quinlan-Jones, E.
THE NHS HEALTH TECHNOLOGY ASSESMENT PROGRAMME (HTA)
1/09/08 → 30/06/12
Project: Research