Lawrence Young

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Publications

  1. 1989
  2. Published

    Subtypes of human papillomavirus 16 in cervical tissue

    Lawrence Young, 2 Dec 1989, In: The Lancet. 334, 8675, p. 1342

    Research output: Contribution to journal › Letter › peer-review

  3. 1990
  4. Published

    Analysis of human papillomavirus type 16 E6-E7 transcription in cervical carcinomas and normal cervical epithelium using the polymerase chain reaction

    Lawrence Young, Jul 1990, In: Journal of General Virology. 71, 7, p. 1473-1477

    Research output: Contribution to journal › Article › peer-review

  5. 1992
  6. Published

    PCR for the detection of genital HPV infection: a mixed blessing

    Lawrence Young, 1992, In: Annals of Medicine. 24, p. 215-219

    Research output: Contribution to journal › Article

  7. Published

    PCR for the detection of genital human papillomavirus infection: a mixed blessing

    Lawrence Young, Rosemary Tierney, John Ellis, Jun 1992, In: Annals of Medicine. 24, 3, p. 215-9 5 p.

    Research output: Contribution to journal › Article › peer-review

  8. 1993
  9. Published

    HLA A2.1-restricted cytotoxic T cells recognizing a range of Epstein-Barr virus isolates through a defined epitope in latent membrane protein LMP2

    William Thomas, Farhat Khanim, Lawrence Young, Martin Rowe & Alan Rickinson, 1993, In: Journal of virology. 67, 12, p. 7428-7435 8 p.

    Research output: Contribution to journal › Article › peer-review

  10. Published

    PCR for the detection of cervical HPV16 infection: the need for standardization

    Rosemary Tierney, John Ellis & Lawrence Young, 19 Jun 1993, In: International Journal of Cancer. 54, 4, p. 700-1 2 p.

    Research output: Contribution to journal › Article › peer-review

  11. 1994
  12. Published

    Latent Epstein-Barr virus infection in cottontop tamarins. A possible model for Epstein-Barr virus infection in humans

    Gerald Niedobitek, Angelo Agathanggelou, Rosemary Tierney, Peter Watkins, Andrea Morgan, Lawrence Young, Oct 1994, In: The American Journal of Pathology. 145, 4, p. 969-78 10 p.

    Research output: Contribution to journal › Article › peer-review

  13. Published

    Epstein-Barr virus latency in blood mononuclear cells: analysis of viral gene transcription during primary infection and in the carrier state

    Rosemary Tierney, Neil Steven, Lawrence Young & Alan Rickinson, Nov 1994, In: Journal of virology. 68, 11, p. 7374-85 12 p.

    Research output: Contribution to journal › Article › peer-review

  14. 1995
  15. Published

    Non-Hodgkin's lymphoma, coeliac disease, and Epstein-Barr virus: a study of 13 cases of enteropathy-associated T- and B-cell lymphoma

    Gerald Niedobitek, Angelo Agathanggelou, Andrew Read, Rosemary Tierney, Lawrence Young, Oct 1995, In: Journal of Pathology. 177, 2, p. 115-22 8 p.

    Research output: Contribution to journal › Article › peer-review

  16. 1996
  17. Published

    Human papillomavirus infection and risk of progression of epithelial abnormalities of the cervix

    Rosemary Tierney & Lawrence Young, Feb 1996, In: British Journal of Cancer. 73, 4, p. 553-556 4 p.

    Research output: Contribution to journal › Article › peer-review

  18. Published

    Analysis of Epstein-Barr virus gene polymorphisms in normal donors and in virus-associated tumors from different geographic locations

    Farhat Khanim, Qing-Yun Yao, Gerald Niedobitek, Alan Rickinson & Lawrence Young, 1 Nov 1996, In: Blood. 88, 9, p. 3491-3501 11 p.

    Research output: Contribution to journal › Article › peer-review

  19. 1999
  20. Published

    CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell surface fas ligand expression and amplifies fas-mediated hepatocyte death during allograft rejection

    Simon Afford, Aris Eliopoulos, Stefan Hubscher, Lawrence Young & David Adams, 18 Jan 1999, In: The Journal of Experimental Medicine. 189, 2, p. 441-6 6 p.

    Research output: Contribution to journal › Article › peer-review

  21. Published

    Effect of Epstein-Barr virus infection on response to chemotherapy and survival in Hodgkin's disease

    Phil Murray, Lucinda Billingham, David Kerr & Lawrence Young, 15 Jul 1999, In: Blood. 94, 2, p. 442-7 6 p.

    Research output: Contribution to journal › Article › peer-review

  22. 2000
  23. Published

    CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily

    Aris Eliopoulos, Pauline Knox, Neil Gallagher, Simon Afford, Lawrence Young & David Adams, Aug 2000, In: Molecular and Cellular Biology. 20, 15, p. 5503-15 13 p.

    Research output: Contribution to journal › Article › peer-review

  24. Published

    CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the TNF superfamily

    Aris Eliopoulos, Neil Gallagher, David Adams, Simon Afford & Lawrence Young, 1 Aug 2000, In: Molecular and Cellular Biology. 20, 15, p. 5503-5515 13 p.

    Research output: Contribution to journal › Article

  25. Published

    Immunotherapy in hepatocellular carcinoma

    Rowan Jones, Lawrence Young & David Adams, 2 Sep 2000, In: Lancet. 356, 9232, p. 784-5 2 p.

    Research output: Contribution to journal › Article › peer-review

  26. 2001
  27. Published

    Adeono-virus mediated expression of dominant negative FGF-receptor-1 reverses the effects of FGF-2 on the function of primary human thyrocytes

    Emma Davies, Helen Cocks, Nicky Green, Peter Searle, Lawrence Young, Ann Logan, Jayne Franklyn & Margaret Eggo, 1 Jan 2001, p. OC7.

    Research output: Contribution to conference (unpublished) › Abstract

  28. Published

    Differential responses of Burkitts lymphoma cells to CD40 ligation: Optimal stimulation requires efficient receptor oligomerisation

    Rachel Chapman, Alan Rickinson & Lawrence Young, 1 Jan 2001, In: Blood. 98, p. 1400-1406 7 p.

    Research output: Contribution to journal › Article

  29. Published

    Epstein-Barr virus infection: basis of malignancy and potential for therapy

    Paul Murray & Lawrence Young, 1 Jan 2001, In: Expert Reviews in Molecular Medicine. 3, p. 1-20 20 p.

    Research output: Contribution to journal › Article

  30. Published

    Gene therapy for colorectal cancer: Therapeutic potential

    Peter Searle, Lawrence Young & David Kerr, 1 Jan 2001, In: BioDrugs. 15, 6, p. 357-367 11 p.

    Research output: Contribution to journal › Article

  31. Published

    In vitro assays to study epithelial cell differentiation

    Christopher Dawson & Lawrence Young, 1 Jan 2001, In: Methods in molecular biology. 174, p. 173-80 8 p.

    Research output: Contribution to journal › Article

  32. Published

    In vitro assays to study epithelial cell growth

    Christopher Dawson & Lawrence Young, 1 Jan 2001, In: Methods in molecular biology. 174, p. 165-72 8 p.

    Research output: Contribution to journal › Article

  33. Published

    Negation of FGF-2 effects on growth and function in primary human thyrocytes and FRTL5 cells by adenovirus-mediated expression of dominant negative FGFR-1

    Emma Davies, Helen Cocks, Nicky Green, Peter Searle, Lawrence Young, Ann Logan, Jayne Franklyn & Margaret Eggo, 1 Jan 2001, p. 131. 1 p.

    Research output: Contribution to conference (unpublished) › Paper

  34. Published

    Nitroimidazole reductase and virally directed enzyme prodrug therapy

    Nicky Green, Vivien Mautner, Lawrence Young, Peter Searle & David Kerr, 1 Jan 2001, In: Cancer Gene Therapy. 8, p. 25-27 3 p.

    Research output: Contribution to journal › Article

  35. Published

    Combined adenovirus-mediated nitroreductase gene delivery and CB1954 treatment: A well-tolerated therapy for established solid tumours

    Peter Searle, Lawrence Young, David Kerr, 1 Feb 2001, In: Molecular Therapy. 3, 2, p. 233-240 8 p.

    Research output: Contribution to journal › Article

  36. Published

    The transmembrane domains of the EBV-encoded latent membrane protein 1 (LMP1) variant CAO regulate enhanced signalling activity

    Sarah Blake, Aris Eliopoulos, Christopher Dawson & Lawrence Young, 10 Apr 2001, In: Virology. 282, 2, p. 278-287 10 p.

    Research output: Contribution to journal › Article

  37. Published

    The promise and potential hazards of adenovirus gene therapy

    Lawrence Young & Vivien Mautner, 1 May 2001, In: Gut. 48, 5, p. 733-736 4 p.

    Research output: Contribution to journal › Article

  38. Published

    Expression of cytokine and chemokine genes in Epstein-Barr virus-associated nasopharyngeal carcinoma: Comparison with Hodgkin's disease

    Lawrence Young, 1 Jun 2001, In: Journal of Pathology. 194, 2, p. 145-151 7 p.

    Research output: Contribution to journal › Article

  39. Published

    Expression of the tumour necrosis factor receptor-associated factors 1 and 2 in Hodgkin's disease

    Paul Murray, Joanne Gough, Karl Baumforth & Lawrence Young, 1 Jun 2001, In: Journal of Pathology. 194, 2, p. 158-164 7 p.

    Research output: Contribution to journal › Article

  40. Published

    Natural history of cervical human papillomavirus infection in young women: a longitudinal cohort study

    Heather Winter & Lawrence Young, 9 Jun 2001, In: Lancet. 357, 9271, p. 1831-1836 6 p.

    Research output: Contribution to journal › Article

  41. Published

    Gene therapy for hepatocellular carcinoma - Teaching old dogs new tricks

    Simon Afford & Lawrence Young, 1 Jul 2001, In: Hepatology. 34, 1, p. 207-209 3 p.

    Research output: Contribution to journal › Article

  42. Published

    South Asian ethnicity and material deprivation increase the risk of Epstein-Barr virus infection in childhood Hodgkin's disease

    Judy Powell, Lawrence Young & Paul Murray, 3 Aug 2001, In: British Journal of Cancer. 85, p. 350-356 7 p.

    Research output: Contribution to journal › Article

  43. Published

    Frequent expression of the tumour necrosis factor receptor-associated factor 1 in latent membrane protein 1-positive post-transplant lymphoproliferative disease and HIV-associated lymphomas

    Paul Murray, Joanne Gough, Karl Baumforth, Lawrence Young, 1 Sep 2001, In: Human Pathology. 32, 9, p. 963-969 7 p.

    Research output: Contribution to journal › Article

  44. Published

    High-level β-catenin/TCF-dependent transgene expression in secondary colorectal cancer tissue

    Lawrence Young, 1 Oct 2001, In: Molecular Therapy. 4, 4, p. 365-371 7 p.

    Research output: Contribution to journal › Article

  45. Published

    The Epstein-Barr virus encoded latent membrane protein 2A augments signaling from latent membrane protein 1

    Christopher Dawson, Sarah Blake & Lawrence Young, 25 Oct 2001, In: Virology. 289, 2, p. 192-207 16 p.

    Research output: Contribution to journal › Article

  46. Published

    CD40 activation-induced, Fas-dependent apoptosis and NF-κB/AP-1 signalling in human intrahepatic biliary epithelial cells

    Simon Afford, Jalal Ahmed-Choudhury, Heather Beard, Aris Eliopoulos, Stefan Hubscher, Lawrence Young & David Adams, 1 Nov 2001, In: FASEB Journal. 15, 13, p. 2345-2354 10 p.

    Research output: Contribution to journal › Article

  47. Published

    LMP1 structure and signal transduction

    Aris Eliopoulos & Lawrence Young, 1 Dec 2001, In: Seminars in Cancer Biology. 11, 6, p. 435-444 10 p.

    Research output: Contribution to journal › Article

  48. 2002
  49. Published

    Disruption of the SH3 domain of PTTG reveals distinct mechanisms of FGF-induction and cell transformation

    Kristien Boelaert, Lesley Tannahill, Jasbir Moore, Lawrence Young, Michael Sheppard, Jayne Franklyn, Neil Gittoes & Christopher McCabe, 1 Jan 2002.

    Research output: Contribution to conference (unpublished) › Abstract

  50. Published

    High incidence of cervical human papillomavirus infection in women during their first sexual relationship

    Heather Winter, Lawrence Young, 1 Jan 2002, In: BJOG. 109, 1, p. 96-98 3 p.

    Research output: Contribution to journal › Article

  51. Published

    The SH3 domain of PTTG differentially mediates FGF-2 transactivation and cell transformation

    Kristien Boelaert, Lesley Tannahill, Jasbir Moore, Lawrence Young, Michael Sheppard, Neil Gittoes, Jayne Franklyn & Christopher McCabe, 1 Jan 2002, p. OR 40-42.

    Research output: Contribution to conference (unpublished) › Paper

  52. Published

    The role of the Epstein-Barr virus in human disease

    Paul Murray & Lawrence Young, 1 Jan 2002, In: Frontiers in Bioscience. 7, 1-3, p. 519-540 22 p.

    Research output: Contribution to journal › Article

  53. Published

    Virus interaction with host immunity

    Lawrence Young, 1 Jan 2002, Critical Care Focus - Inflammation and Immunity. Vol. 10.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  54. Published

    Induction of apoptosis by chemotherapeutic drugs: the role of FADD in activation of caspase-8 and synergy with death receptor ligands in ovarian carcinoma cells

    Anne Milner, Daniel Palmer, Aris Eliopoulos, Pauline Knox, Christopher Poole, David Kerr & Lawrence Young, 1 Mar 2002, In: Cell Death & Differentiation . 9, 3, p. 287-300 14 p.

    Research output: Contribution to journal › Article

  55. Published

    Low prevalence of Epstein-Barr virus in incident gastric adenocarcinomas from the United Kingdom

    Joanne Gough, David Rowlands, Lawrence Young & Paul Murray, 4 Mar 2002, In: British Journal of Cancer. 86, 5, p. 702-704 3 p.

    Research output: Contribution to journal › Article

  56. Published

    The oncogenic protein kinase Tpl-2/Cot contributes to Epstein-Barr virus-encoded latent infection membrane protein 1-induced NFκB signaling downstream of TRAF2

    Aris Eliopoulos, Sarah Blake, Paul Murray & Lawrence Young, 27 Mar 2002, In: Journal of virology. 76, 9, p. 4567-4579 13 p.

    Research output: Contribution to journal › Article

  57. Published

    CD40 activation in epithelial ovarian carcinoma cells modulates growth, apoptosis and cytokine secretion

    Neil Gallagher, Aris Eliopoulos, Angelo Agathanggelou & Lawrence Young, 1 Apr 2002, In: Molecular Pathology. 55, 2, p. 110-120 11 p.

    Research output: Contribution to journal › Article

  58. Published

    Population depletion activates autonomous CD154-dependent survival in biopsy-like Burkitt lymphoma cells

    Aris Eliopoulos, Michelle Holder, Anita Chamba, Gillian Grafton, Lawrence Young & John Gordon, 1 May 2002, In: Blood. 99, 9, p. 3411-3418 8 p.

    Research output: Contribution to journal › Article

  59. Published

    Epstein-Barr virus and human cancer [Book Review]

    Lawrence Young, 1 Jul 2002, In: British Journal of Cancer. 87, 1, p. 127-128 2 p.

    Research output: Contribution to journal › Article

  60. Published

    Interleukin 6 expression by Hodgkin/Reed-Sternberg cells is associated with the presence of 'B' symptoms and failure to achieve complete remission in patients with advanced Hodgkin's disease

    Lucinda Billingham, Joanne Gough, Lawrence Young & Paul Murray, 1 Jul 2002, In: British Journal of Haematology. 118, 1, p. 195-201 7 p.

    Research output: Contribution to journal › Article

  61. Published

    Reactivity and isotype profiling of monoclonal antibodies using multiple antigenic peptides

    Paul Murray, Lawrence Young, Karl Baumforth, 1 Oct 2002, In: Hybrid Hybridomics. 21, 5, p. 393-398 6 p.

    Research output: Contribution to journal › Article

  62. Published

    TRAF1 is a critical regulator of JNK signalling by the TRAF-binding domain of the Epstein-Barr virus-encoded latent infection membrane protein 1 (LMP1) but not CD40

    Aris Eliopoulos, Sarah Blake, Clare Davies, Paul Murray & Lawrence Young, 20 Dec 2002, In: Journal of virology. 77, 2, p. 1316-1328 13 p.

    Research output: Contribution to journal › Article

  63. 2003
  64. Published

    BCL2 expression predicts survival in patients receiving synchronous chemoradiotherapy in advanced transitional cell carcinoma of the bladder

    Syed Hussain, Louise Hiller, Paul Murray, Lawrence Young & Nicholas James, 1 Jan 2003, In: Oncology reports. 10, p. 571-576 6 p.

    Research output: Contribution to journal › Article

  65. Published

    Dendritic cell vaccination for hepatocellular carcinoma

    Daniel Palmer, Nazzia Mirza, Jane Steele, Neil Steven, Lawrence Young, David Adams, 1 Jan 2003, p. 280A.

    Research output: Contribution to conference (unpublished) › Abstract

  66. Published

    Inhibition of metalloproteinase cleavage enhances the cytotoxicity of Fas ligand

    Anne Milner, Nicky Green, Aris Eliopoulos & Lawrence Young, 1 Jan 2003, In: Journal of Immunology. 170, p. 677-685 9 p.

    Research output: Contribution to journal › Article

  67. Published

    Reactivity with a monoclonal antibody to Epstein-Barr virus (EBV) nuclear antigen 1 defines a subset of aggressive breast cancers in the absence of the EBV genome

    Paul Murray, Andrew Bell, Judith Timms, David Rowlands, Christopher McConkey & Lawrence Young, 1 Jan 2003, In: Cancer Research. 63, p. 2338-2343 6 p.

    Research output: Contribution to journal › Article

  68. Published

    Human papillomavirus type 18 and rapidly progressing cervical intraepithelial neoplasia

    Stuart Collins, Heather Winter & Lawrence Young, 4 Jan 2003, In: Lancet. 361, 9351, p. 40-43 4 p.

    Research output: Contribution to journal › Article

  69. Published

    Epstein-Barr virus latent membrane protein 1 (LMP1) activates the phosphatidylinositol 3-kinase/Akt pathway to promote cell survival and induce actin filament remodeling

    Christopher Dawson, Aris Eliopoulos & Lawrence Young, 31 Jan 2003, In: Journal of Biological Chemistry. 278, 6, p. 3694-3704 11 p.

    Research output: Contribution to journal › Article

  70. Published

    The effect of Epstein-Barr virus status on survival in age and sex defined subgroups of patients with advanced Hodgkin's disease

    Lucinda Billingham, Joanne Gough, Lawrence Young & Paul Murray, 1 Feb 2003, In: Annals of Oncology. 14, 2, p. 282-290 9 p.

    Research output: Contribution to journal › Article

  71. Published

    Absence of Epstein-Barr virus DNA in the tumour cells of European hepatocellular carcinoma

    Andrew Bell, Judith Timms, Stefan Hubscher, Lawrence Young & Paul Murray, 15 Feb 2003, In: Virology. 306, 2, p. 236-243 8 p.

    Research output: Contribution to journal › Article

  72. Published

    Pro-apoptotic genes BAX and CD40L are predictors of survival in transitional cell carcinoma of the bladder

    Syed Hussain, Louise Hiller, Paul Murray, Lawrence Young & Nicholas James, 24 Feb 2003, In: British Journal of Cancer. 88, 4, p. 586-592 7 p.

    Research output: Contribution to journal › Article

  73. Published

    Immune enhancement of nitroreductase-induced cytotoxicity: Studies using a bicistronic adenovirus vector

    Nicky Green, Peter Searle, David Kerr & Lawrence Young, 10 Mar 2003, In: International Journal of Cancer. 104, 1, p. 104-112 9 p.

    Research output: Contribution to journal › Article

  74. Published

    Differential induction of nuclear factor-κB and activator protein-1 activity after CD40 ligation is associated with primary human hepatocyte apoptosis or intrahepatic endothelial cell proliferation

    Jalal Ahmed-Choudhury, Lawrence Young, David Adams & Simon Afford, 1 Apr 2003, In: Molecular Biology of the Cell. 14, 4, p. 1334-1345 12 p.

    Research output: Contribution to journal › Article

  75. Published

    Epstein-Barr virus and oncogenesis: From latent genes to tumours

    Lawrence Young & Paul Murray, 11 Aug 2003, In: Oncogene. 22, 33, p. 5108-5121 14 p.

    Research output: Contribution to journal › Article

  76. Published

    Epstein-Barr virus nuclear antigen 1 (EBNA1) induced cytotoxicity in epithelial cells is associated with EBNA1 degradation and processing.

    Christopher Dawson & Lawrence Young, 1 Sep 2003, In: Virology. 313, 2, p. 663-76 14 p.

    Research output: Contribution to journal › Article

  77. Published

    Mechanism of cell death induced by the novel enzyme-prodrug combination, nitroreductase/CB1954, and identification of synergism with 5-fluorouracil

    Daniel Palmer, Anne Milner & Lawrence Young, 1 Sep 2003, In: British Journal of Cancer. 89, 5, p. 944-950 7 p.

    Research output: Contribution to journal › Article

  78. Published

    Seasonal differences in the onset of the EBV-positive and -negative forms of paediatric Hodgkin's lymphoma

    Anne Reiman, Judy Powell, Richard Grundy, Lawrence Young & Paul Murray, 6 Oct 2003, In: British Journal of Cancer. 89, 7, p. 1200-1201 2 p.

    Research output: Contribution to journal › Article

  79. Published

    The Epstein-Barr virus encoded latent infection membrane protein 1 (LMP1) regulates the processing of p100 NK-κB2 to p52 via an IKKγ/NEMO-independent signaling pathway

    Aris Eliopoulos, Jorge Caamano, Joanne Gough, Paul Murray & Lawrence Young, 23 Oct 2003, In: Oncogene. 22, 48, p. 7557-7569 13 p.

    Research output: Contribution to journal › Article

  80. 2004
  81. Published

    An interferon-γ ELISPOT and immunohistochemical investigation of cytotoxic T lymphocyte-mediated tumour immunity in patients with paraneoplastic cerebellar degeneration and anti-Yo antibodies

    Jane Steele, Caroline Savage, John Winer & Lawrence Young, 1 Jan 2004, In: Journal of Neuroimmunology. 150, p. 98-106 9 p.

    Research output: Contribution to journal › Article

  82. Published

    CD40 expression in prostate cancer: A potential diagnostic and therapeutic molecule

    Daniel Palmer, Syed Hussain, Peter Cooke, Lawrence Young & Nicholas James, 1 Jan 2004, In: Oncology reports. 12, p. 679-682 4 p.

    Research output: Contribution to journal › Article

  83. Published

    Carbonic anhydrase IX, a marker of hypoxia: Correlation with clinical outcome in transitional cell carcinoma of the bladder

    Syed Hussain, Daniel Palmer, Louise Hiller, Paul Murray, Lawrence Young & Nicholas James, 1 Jan 2004, In: Oncology reports. 11, p. 1005-1010 6 p.

    Research output: Contribution to journal › Article

  84. Published

    Cytokine mediated modulation of the myc network in barrett's metaplasia

    Lawrence Young, Moray Campbell & Chris Tselepis, 1 Jan 2004.

    Research output: Contribution to conference (unpublished) › Abstract

  85. Published

    Enhanced efficacy of Escherichia coli nitroreductase/CB1954 prodrug activation gene therapy using an E1B-55K-deleted oncolytic adenovirus vector

    Joanne Gough, Vivien Mautner, Lawrence Young & Peter Searle, 1 Jan 2004, In: Gene Therapy. 11, p. 1126-1236 111 p.

    Research output: Contribution to journal › Article

  86. Published

    Epstein-Barr virus associated cancers: Aetiology and treatment

    Victor Lopes, Lawrence Young & Paul Murray, 1 Jan 2004, In: Herpes. 10, p. 78-82 5 p.

    Research output: Contribution to journal › Article

  87. Published

    Epstein-Barr virus: 40 years on

    Lawrence Young & Alan Rickinson, 1 Jan 2004, In: Nature Reviews Cancer. 4, p. 757-768 12 p.

    Research output: Contribution to journal › Review article

  88. Published

    Expression of tumour necrosis factor receptor-associated factor 1 (TRAF1) in nasopharyngeal carcinoma: Possible up-regulation by Epstein-Barr virus latent membrane protein 1

    Christopher Dawson, Lawrence Young, 1 Jan 2004, In: International Journal of Cancer. 112, p. 265-272 8 p.

    Research output: Contribution to journal › Article

  89. Published

    Frequent epigenetic inactivation of the RASSF1A tumor suppresor gene in Hodgkin's lymphoma

    Paul Murray, Angelo Agathanggelou, Farida Latif, Richard Grundy, Lawrence Young, 1 Jan 2004, In: Oncogene. 23, 6, p. 1326-1331 6 p.

    Research output: Contribution to journal › Article

  90. Published

    Inhibition of phosphatidylinositol 3-kinase- and ERK MAPK-regulated protein synthesis reveals the pro-apoptotic properties of CD40 ligation in carcinoma cells

    Clare Davies, Mike Wakelam, Lawrence Young & Aris Eliopoulos, 1 Jan 2004, In: Journal of Biological Chemistry. 279, p. 1010-1019 10 p.

    Research output: Contribution to journal › Article

  91. Published

    PTTG's C-terminal PXXP motifs modulate critical cellular processes in vitro

    Kristien Boelaert, Lesley Tannahill, Farhat Khanim, Margaret Eggo, Jasbir Moore, Lawrence Young, Neil Gittoes, Jayne Franklyn & Christopher McCabe, 1 Jan 2004, In: Journal of Molecular Endocrinology. 33, p. 663-677 15 p.

    Research output: Contribution to journal › Article

  92. Published

    TNF receptors and their ligands: in sickness and in health, in life and death

    Lawrence Young & Aris Eliopoulos, 1 Jan 2004, In: Current Opinion in Pharmacology. 4, p. 311-313 3 p.

    Research output: Contribution to journal › Review article

  93. Published

    The role of CD40 in the pathogenesis and treatment of cancer

    Aris Eliopoulos & Lawrence Young, 1 Jan 2004, In: Current Opinion in Pharmacology. 4, p. 360-367 8 p.

    Research output: Contribution to journal › Review article

  94. Published

    Virus directed enzyme prodrug therapy: Intratumoural administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer

    Daniel Palmer, Vivien Mautner, Stefan Hubscher, Seran Hill, Peter Searle, Lawrence Young, Nicholas James, 29 Mar 2004, In: Journal of Clinical Oncology. 22, p. 1546-1552 7 p.

    Research output: Contribution to journal › Article

  95. Published

    Epstein-Barr virus latent membrane protein 1 (LMP1) up-regulates Id1 expression in nasopharyngeal epithelial cells

    Aris Eliopoulos, Lawrence Young, 5 Apr 2004, In: Oncogene. 23, p. 4488-4494 7 p.

    Research output: Contribution to journal › Article

  96. Published

    Expression of the cellular FLICE inhibitory protein (c-FLIP) protects Hodgkin's lymphoma cells from autonomous Fas-mediated death

    Amanda Dutton, John O'Neil, Anne Milner, Lawrence Young & Paul Murray, 19 Apr 2004, In: National Academy of Sciences. Proceedings. 101, p. 6611-6616 6 p.

    Research output: Contribution to journal › Article

  97. Published

    Epstein-Barr virus encoded LMP2A regulates viral and cellular gene expression via modulation of the NF-κB transcription factor pathway

    Suzanne Stewart, Christopher Dawson, John Curnow & Lawrence Young, 25 Oct 2004, In: National Academy of Sciences. Proceedings. 101, p. 15730-15735 6 p.

    Research output: Contribution to journal › Article › peer-review

  98. Published

    Nitroreductase: A prodrug-activating enzyme for cancer gene therapy

    Peter Searle, Andrew Lovering, Jane Grove, Chris Guise, Nicholas James, Vivien Mautner, Lawrence Young, David Kerr, Scott White & Eva Hyde, 1 Nov 2004, In: Clinical and Experimental Pharmacology and Physiology. 31, 11, p. 811-816 6 p.

    Research output: Contribution to journal › Article › peer-review

  99. 2005
  100. Published

    Activation of CD40 in cervical carcinoma cells facilitates CTL responses and augments chemotherapy-induced apoptosis

    Seran Hill, Andrew Hislop, Clare Davies, David Luesley, Alan Rickinson, Lawrence Young & Aris Eliopoulos, 1 Jan 2005, In: Journal of Immunology. 174, p. 41-50 10 p.

    Research output: Contribution to journal › Article

  101. Published

    The Epstein-Barr virus encoded LMP2A and LMP2B proteins promote epithelial cell spreading and motility

    Lawrence Young & Christopher Dawson, 1 Feb 2005, In: Journal of virology. 79, p. 1789-1802 14 p.

    Research output: Contribution to journal › Article

  102. Published

    Constitutive activation of phosphatidyl-inositide 3 kinase contributes to the survival of Hodgkin's lymphoma cells through a mechanism involving AKT kinase and mTOR

    Amanda Dutton, Christopher Dawson, Lawrence Young & Paul Murray, 1 Mar 2005, In: Journal of Pathology. 205, p. 498-506 9 p.

    Research output: Contribution to journal › Article

  103. Published

    Inhibition of NF-κB enhances the cytotoxicity of virus-directed enzyme prodrug therapy and oncolytic adenovirus cancer gene therapy

    Daniel Palmer, Peter Searle & Lawrence Young, 31 Mar 2005, In: Gene Therapy. 12, p. 1187-1197 11 p.

    Research output: Contribution to journal › Article

  104. Published

    PTTG Binding Factor (PBF) - a Novel Transforming Gene in Thyroid Tumorigenesis

    Kristien Boelaert, Lesley Tannahill, Dae Kim, Margaret Eggo, Neil Gittoes, Lawrence Young, Jayne Franklyn & Christopher McCabe, 5 Apr 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 7, p. 4341-4349 9 p.

    Research output: Contribution to journal › Article

  105. Published

    Proximity of first intercourse to menarche and the risk of human papillomavirus infection: A longitudinal study

    Stuart Collins, Heather Winter, Lawrence Young, 10 Apr 2005, In: International Journal of Cancer. 114, 3, p. 498-500 3 p.

    Research output: Contribution to journal › Article

  106. Published

    Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A

    Lawrence Young, Christopher Dawson, 1 May 2005, In: Journal of virology. 79, p. 5499-5506 8 p.

    Research output: Contribution to journal › Article

  107. Published

    NF-κB overrides the apoptotic program of TNF receptor 1 but not CD40 in carcinoma cells

    Clare Davies, Danai Bem, Lawrence Young & Aris Eliopoulos, 1 Jun 2005, In: Cellular Signalling. 17, p. 729-738 10 p.

    Research output: Contribution to journal › Article

  108. Published

    Role of sexual behavior in the acquisition of asymptomatic Epstein-Barr virus infection: a longitudinal study.

    Stuart Collins, Ankit Rao, Lawrence Young & Paul Murray, 1 Jun 2005, In: The Pediatric Infectious Disease Journal . 24, 6, p. 498-502 5 p.

    Research output: Contribution to journal › Article

  109. Published

    The role of sexual behaviour in the acquisition of asymptomatic EBV infection

    Lawrence Young & Paul Murray, 1 Jun 2005, In: The Pediatric Infectious Disease Journal . 24, p. 498-502 5 p.

    Research output: Contribution to journal › Article

  110. Published

    Constitutive activation of the CD40 pathway promotes cell transformation and neoplastic growth

    Christopher Dawson, Suzanne Stewart, John Gordon, Paul Murray, Lawrence Young & Aris Eliopoulos, 8 Aug 2005, In: Oncogene. 24, p. 7913-7923 11 p.

    Research output: Contribution to journal › Article

  111. Published

    Induction of autotaxin by the Epstein-Barr virus promotes the growth and survival of Hodgkin lymphoma cells

    Karl Baumforth, Joanne Gough, Trevor Pettitt, Wenbin Wei, Susan Morgan, Tatjana Stankovic, Dickens Pratt, Mike Wakelam, Lawrence Young & Paul Murray, 15 Sep 2005, In: Blood. 106, p. 2138-2146 9 p.

    Research output: Contribution to journal › Article

  112. Published

    TRAF6 is required for TRAF2-dependent CD40 signal transduction in non-haemopoietic cells

    Clare Davies, Lawrence Young & Aris Eliopoulos, 15 Nov 2005, In: Molecular and Cellular Biology. 25, p. 9806-9819 14 p.

    Research output: Contribution to journal › Article

  113. 2006
  114. Published

    Epstein-Barr virus (EBV) and its associated human cancers-genetics, epigenetics, pathobiology and novel therapeutics

    Lawrence Young & Paul Murray, 1 Jan 2006, In: Frontiers in Bioscience. 11, p. 2672-2713 42 p.

    Research output: Contribution to journal › Review article

  115. Published

    Viral gene therapy strategies: From basic science to clinical application

    Lawrence Young, Peter Searle, David Onion & Vivien Mautner, 1 Jan 2006, In: Journal of Pathology. 208, p. 299-318 20 p.

    Research output: Contribution to journal › Article

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