Kristien Boelaert

Publications

  1. 2019
  2. Published

    A high-throughput yellow fluorescent protein (YFP) cell-based screen identifies autophagy modulators to increase the effectiveness of radioiodine therapy

    Martin Read, Brookes, K., Alice Fletcher, Thornton, C., Alshahrani, M., Nieto, H., Khan, R., Webster, J., Haggie, P., Verkman, A., Luke Alderwick, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 Nov 2019, In : Endocrine Abstracts. 65, 1 p., OC4.1.

    Research output: Contribution to journalAbstract

  3. E-pub ahead of print
  4. Published

    Patients treated for hyperthyroidism are at increased risk of becoming obese: findings from a large prospective secondary care cohort

    Barbara Torlinska, Nichols, L., Mohammed, M. A., McCabe, C. & Kristien Boelaert, 15 Oct 2019, In : Thyroid. 29, 10, p. 1380-1389 10 p.

    Research output: Contribution to journalArticle

  5. Published

    Dimerization of the sodium/iodide symporter

    Thompson, R. J., Alice Fletcher, Brookes, K., Nieto, H., Alshahrani, M. M., Jonathan Wolf Mueller, Fine, N. H. F., David Hodson, Kristien Boelaert, Martin Read, Vicki Smith & Christopher McCabe, Oct 2019, In : Thyroid. 29, 10, p. 1485-1498 14 p.

    Research output: Contribution to journalArticle

  6. Published
  7. Published

    Risk of incident circulatory disease in patients treated for differentiated thyroid carcinoma with no history of cardiovascular disease

    Toulis, K. A., Viola, D., Gkoutos, G., Keerthy, D., Kristien Boelaert & Krishnarajah Nirantharakumar, 1 Aug 2019, In : Clinical Endocrinology. 91, 2, p. 323-330 8 p.

    Research output: Contribution to journalArticle

  8. Published

    Antigen-specific immunotherapy with thyrotropin receptor peptides in Graves' hyperthyroidism: a phase I study

    Pearce, S. H. S., Dayan, C., Wraith, D. C., Barrell, K., Olive, N., Jansson, L., Walker-Smith, T., Carnegie, C., Martin, K. F., Kristien Boelaert, Gilbert, J., Higham, C. E., Muller, I., Murray, R. D., Perros, P., Razvi, S., Vaidya, B., Wernig, F. & Kahaly, G. J., 17 Jul 2019, In : Thyroid. 29, 7, p. 1003-1011 9 p.

    Research output: Contribution to journalArticle

  9. Published

    Glucocorticoid induced adrenal insufficiency is common in steroid treated glomerular diseases - proposed strategy for screening and management

    Karangizi, A. H. K., Al-Shaghana, M., Logan, S., Criseno, S., Webster, R., Kristien Boelaert, Hewins, P. & Lorraine Harper, 6 May 2019, In : BMC Nephrology. 20, 1, 154.

    Research output: Contribution to journalArticle

  10. Published

    Knowledge of thyroid eye disease in Graves’ Disease patients with and without orbitopathy

    Matthew Edmunds & Kristien Boelaert, 9 Apr 2019, In : Thyroid. 29, 4, p. 557-562 6 p.

    Research output: Contribution to journalArticle

  11. Published

    Levothyroxine in Women with Thyroid Peroxidase Antibodies before Conception

    Dhillon-smith, R., Middleton, L., Sunner, K., Cheed, V., Baker, K., Farrell-Carver, S., Bender Atik, R., Agrawal, R., Bhatia, K., Edi-Osagie, E., Ghobara, T., Gupta, P., Jurkovic, D., Khalaf, Y., MacLean, M., McCabe, C., Mulbagal, K., Nunes, N., Overton, C., Quenby, S. & 14 others, Rai, R., Raine-Fenning, N., Robinson, L., Ross, J., Sizer, A., Small, R., Alex Tan, Underwood, M., Mark Kilby, Kristien Boelaert, Jane Daniels, Shakila Thangaratinam, Chan, S. Y. & Arri Coomarasamy, 4 Apr 2019, In : The New England Journal of Medicine. 380, p. 1316-1325

    Research output: Contribution to journalArticle

  12. Published

    Adjuvant rituximab, a potential treatment for the young patient with Graves' hyperthyroidism (RiGD): study protocol for a single-arm, single-stage, phase II trial

    Cole, M., Hynes, A. M., Howel, D., Hall, L., Abinun, M., Allahabadia, A., Barrett, T., Kristien Boelaert, Drake, A. J., Dimitri, P., Kirk, J., Zammitt, N., Pearce, S. & Cheetham, T., 21 Jan 2019, In : BMJ open. 9, 1, 10 p., e024705.

    Research output: Contribution to journalArticle

  13. Published

    Liothyronine cost and prescriptions in England

    Taylor, P. N., Razvi, S., Muller, I., Wass, J., Dayan, C. M., Chatterjee, K. & Kristien Boelaert, 1 Jan 2019, In : The Lancet Diabetes and Endocrinology. 7, 1, p. 11-12 2 p.

    Research output: Contribution to journalLetter

  14. 2018
  15. Published

    Biochemical analysis of radioiodine uptake enhancement in endocrine cancer

    Alshahrani, M., Alice Fletcher, Thornton, C., Brookes, K., Hannah Nieto, Thompson, R., Martin Read, Kristien Boelaert, Christopher McCabe & Vicki Smith, 1 Nov 2018, In : Endocrine Abstracts. 59, 1 p., OC2.4.

    Research output: Contribution to journalArticle

  16. Published
  17. Published

    Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism

    Cangul, H., Liao, X., Schoenmakers, E., Kero, J., Barone, S., Srichomkwun, P., Iwayama, H., Serra, E. G., Saglam, H., Eren, E., Tarim, O., Nicholas, A. K., Zvetkova, I., Anderson, C. A., Frankl, F. E. K., Boelaert, K., Ojaniemi, M., Jääskeläinen, J., Patyra, K., Löf, C. & 7 others, Williams, E. D., Soleimani, M., Timothy Barrett, Eamonn Maher, Chatterjee, V. K., Refetoff, S. & Schoenmakers, N., 18 Oct 2018, In : JCI Insight. 3, 20, 11 p., e99631.

    Research output: Contribution to journalAbstract

  18. E-pub ahead of print
  19. Published

    PO-124 PTTG and PBF functionally interact with P53 and predict overall survival in head and neck cancer

    Martin Read, Modasia, B., Alice Fletcher, Thompson, R., Baker, K., Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 1 Jul 2018, In : ESMO Open. 3, Suppl. 2, p. A69-A69 1 p.

    Research output: Contribution to journalAbstract

  20. Published

    Yellow fluorescent protein (YFP) as a biosensor for intracellular iodide in thyroid cancer cells

    Martin Read, Baker, K., Thornton, C., Alshahrani, M., Alice Fletcher, Thompson, R., Haggie, P., Verkman, A., Kristien Boelaert, Vicki Smith & Christopher McCabe, 15 May 2018.

    Research output: Contribution to conference (unpublished)Abstract

  21. Published
  22. Published
  23. 2017
  24. Published

    Functional consequences of the first reported mutations of the proto-oncogene PTTG1IP/PBF

    Imruetaicharoenchoke, W., Alice Fletcher, Wenqi Lu, Watkins, RJ., Modasia, B., Poole, V., Hannah Nieto, Thompson, R., Kristien Boelaert, Martin Read, Vicki Smith & Christopher McCabe, Sep 2017, In : Endocrine-related cancer. 24, 9, p. 459-474

    Research output: Contribution to journalArticle

  25. Published

    MANAGEMENT OF ENDOCRINE DISEASE: Subclinical thyrotoxicosis: prevalence, causes and choice of therapy

    Carlé, A., Andersen, S. L., Kristien Boelaert & Laurberg, P., Jun 2017, In : European Journal of Endocrinology. 176, 6, p. R325-R337

    Research output: Contribution to journalReview article

  26. E-pub ahead of print

    Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer

    Martin Read, Fong, J., Modasia, B., Alice Fletcher, Imruetaicharoenchoke, W., Thompson, R., Hannah Nieto, John Reynolds, Bacon, A., Mallick, U., Hackshaw, A., Watkinson, J., Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 15 May 2017, In : Oncogene. 72326.

    Research output: Contribution to journalArticle

  27. Published

    Comparative analysis of human and mouse expression data identifies proto-oncogene PTTG- and PBF-associated genes in thyroid cancer

    Martin Read, Fong, J., Imruetaicharoenchoke, W., Modasia, B., Hannah Nieto, Alice Fletcher, Thompson, R., Neil Sharma, Watkinson, J., Andrew Turnell, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 Feb 2017, In : Thyroid Research. 10(Suppl 1), 2

    Research output: Contribution to journalAbstract

  28. Published

    Controlled Antenatal Thyroid Study: Obstetric Outcomes

    Taylor, P., Lacey, A., Thayer, D., Yusof, M., Tabasum, A., Muller, I., Marsh, L., Ludgate, M., Rees, A., Kristien Boelaert, Shiaoyng Chan, Nelson, S., Rees, A., Lazarus, J., Dayan, C., Vaidya, B. & Okosieme, O., 13 Feb 2017, In : Thyroid Research. 10(Suppl 1), 2, p. 2 1 p., O1.

    Research output: Contribution to journalAbstract

  29. Published

    Pharmacological enhancement of radioiodine uptake using Src kinase inhibitors

    Poole, V., Alice Fletcher, Modasia, B., Neil Sharma, Thompson, R., Imruetaicharoenchoke, W., Martin Read, Kristien Boelaert, Christopher McCabe & Vicki Smith, 13 Feb 2017, In : Thyroid Research. 10(Suppl 1), 2, p. 2 1 p., O2.

    Research output: Contribution to journalAbstract

  30. 2016
  31. Published

    Pro-invasive effect of proto-oncogene PBF is modulated by an interaction with cortactin

    Rachel Spruce, Imruetaicharoenchoke, W., Martin Read, Neil Sharma, Poole, V. L., Gentillin, E., Bansal, S., Bosseboeuf, E., Rachel Fletcher, Nieto, H. R., Mallick, U., Hackshaw, A., Hisham Mehanna, Kristien Boelaert, Vicki Smith & Christopher McCabe, Dec 2016, In : The Journal of clinical endocrinology and metabolism. 101, 12, p. 4551-4563

    Research output: Contribution to journalArticle

  32. Published

    High tumoral expression of PBF and PTTG modulates the DNA damage response and is associated with poor survival in thyroid cancer

    Martin Read, Jim Fong, Imruetaicharoenchoke, W., Nieto, H., Modasia, B., Alice Fletcher, Thompson, R., Neil Sharma, Bacon, A., Watkinson, J., Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 4 Nov 2016, In : Endocrine Abstracts. 44, P246.

    Research output: Contribution to journalAbstract

  33. Published

    Thyroid stimulating hormone in thyroid cancer: does it matter?

    Hannah Nieto & Kristien Boelaert, 1 Nov 2016, In : Endocrine-related cancer. 23, 11, ERC-16-0328.

    Research output: Contribution to journalArticle

  34. Published

    Multifocality in Sporadic Medullary Thyroid Carcinoma: An International Multicenter Study

    Essig, G. F., Porter, K., Schneider, D., Arpaia, D., Lindsey, S. C., Busonero, G., Fineberg, D., Fruci, B., Boelaert, K., Smit, J. W., Meijer, J. A. A., Duntas, L. H., Sharma, N., Costante, G., Filetti, S., Sippel, R. S., Biondi, B., Topliss, D. J., Pacini, F., Maciel, R. M. B. & 2 others, Walz, P. C. & Kloos, R. T., Nov 2016, In : Thyroid. 26, 11, p. 1563-1572 10 p.

    Research output: Contribution to journalArticle

  35. Published

    WOMEN IN CANCER PROFILE: From bedside to bench and back: my journey in thyroid disease

    Kristien Boelaert, Nov 2016, In : Endocrine-related cancer. 23, 11, p. 9-13

    Research output: Contribution to journalSpecial issue

  36. Published
  37. Published

    Comparative analysis of human and mouse expression data identifies proto-oncogene PTTG- and PBF-associated genes in thyroid cancer

    Martin Read, Fong, J., Imruetaicharoenchoke, W., Modasia, B., Hannah Nieto, Alice Fletcher, Thompson, R., Neil Sharma, Watkinson, J., Andrew Turnell, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 May 2016.

    Research output: Contribution to conference (unpublished)Abstract

  38. Published

    The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer

    Martin Read, Seed, R. I., Modasia, B., Kwan, P. P. K., Sharma, N., Vicki Smith, Rachel Spruce, Bansal, S., Gagliano, T., Stratford, A. L., Ismail, T., Wakelam, M. J. O., Dae Kim, Stephen Ward, Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Jan 2016, In : Molecular Carcinogenesis. 55, 1, p. 15-26

    Research output: Contribution to journalArticle

  39. 2015
  40. Published

    Distinct p53 response profiles in transgenic mouse models of thyroid-specific PBF and PTTG expression

    Martin Read, Fong, J., Imruetaicharoenchoke, W., Modasia, B., Lewy, G., Ryan, G., Neil Sharma, Vicki Smith, Watkinson, J., Kristien Boelaert & Christopher McCabe, Nov 2015, In : Endocrine Abstracts. 38, P149.

    Research output: Contribution to journalAbstract

  41. E-pub ahead of print

    Effectiveness of metyrapone in treating Cushing's Syndrome: a retrospective multicenter study in 195 patients

    Daniel, E., Aylwin, S., Mustafa, O., Ball, S., Munir, A., Boelaert, K., Chortis, V., Cuthbertson, D. J., Daousi, C., Rajeev, S. P., Davis, J., Cheer, K., Drake, W., Gunganah, K., Grossman, A., Gurnell, M., Powlson, A. S., Karavitaki, N., Huguet, I., Kearney, T. & 8 others, Mohit, K., Meeran, K., Hill, N., Rees, A., Lansdown, A. J., Trainer, P. J., Minder, A-E. H. & Newell-Price, J., 9 Sep 2015, In : The Journal of clinical endocrinology and metabolism. 100, 11, jc20152616.

    Research output: Contribution to journalArticle

  42. Published
  43. Published

    Management of primary hypothyroidism: statement by the British Thyroid Association Executive Committee

    Okosieme, O., Gilbert, J., Abraham, P., Kristien Boelaert, Dayan, C., Gurnell, M., Leese, G., Christopher McCabe, Perros, P., Vicki Smith, Williams, G. & Vanderpump, M., 23 May 2015, In : Clinical Endocrinology.

    Research output: Contribution to journalArticle

  44. Published
  45. Published

    Miscellaneous Hormones

    Vasileios Chortis & Kristien Boelaert, 2015, Side Effects of Drugs. Elsevier, Vol. 37. p. 539-558

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  46. 2014
  47. Published

    Autoimmune encephalopathy in the context of Graves' disease with ophthalmopathy

    Vasileios Chortis, Matthew Edmunds, Littleton, E. T. & Kristien Boelaert, Dec 2014, In : Clinical Endocrinology. 81, 6, p. 936-7 2 p.

    Research output: Contribution to journalArticle

  48. Published

    One Base Deletion (c.2422delT) in the TPO Gene Causes Severe Congenital Hypothyroidism

    Cangul, H., Kristien Boelaert, Timothy Barrett, Dogan, M., Saglam, Y., Kendall, M. & Maher, E., 5 Sep 2014, In : J Clin res Pediatr Endocrinol. 6, 3, p. 169-73

    Research output: Contribution to journalArticle

  49. Published
  50. Published

    The PTTG1-binding factor (PBF/PTTG1IP) regulates p53 activity in thyroid cells

    Martin Read, Seed, R. I., Jim Fong, Modasia, B., Ryan, G. A., Rachel Spruce, Gagliano, T., Vicki Smith, Stratford, A. L., Kwan, P. K., Neil Sharma, Dixon, O. M., Watkinson, J. C., Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Apr 2014, In : Endocrinology. 155, 4, p. 1222-34 13 p.

    Research output: Contribution to journalArticle

  51. Published
  52. Published
  53. 2013
  54. Published
  55. Published

    Fine needle aspiration and medulla

    Essig, G., Porter, K., Schneider, D., Debora, A., Lindsey, S., Busonero, G., Fineberg, D., Fruci, B., Boelaert, K., Smit, J., Meijer, J., Duntas, L., Sharma, N., Costante, G., Filetti, S., Sippel, R., Biondi, B., Topliss, D., Pacini, F., MacIel, R. & 2 others, Walz, P. & Kloos, R., 1 Nov 2013, In : Endocrine Practice. 19, 6, p. 920-927 8 p.

    Research output: Contribution to journalArticle

  56. Published

    Thyroid dyshormonogenesis is mainly caused by TPO mutations in consanguineous community

    Cangul, H., Aycan, Z., Olivera-Nappa, A., Saglam, H., Schoenmakers, N. A., Kristien Boelaert, Cetinkaya, S., Tarim, O., Bober, E., Darendeliler, F., Bas, V., Demir, K., Aydin, B. K., Kendall, M., Cole, T., Högler, W., Chatterjee, V. K. K., Timothy Barrett & Eamonn Maher, Aug 2013, In : Clinical Endocrinology. 79, 2, p. 275-81 7 p.

    Research output: Contribution to journalArticle

  57. Published

    Regulation of Pituitary Tumor Transforming Gene (PTTG) expression and phosphorylation in thyroid cells

    Lewy, G. D., Ryan, G. A., Martin Read, Jim Fong, Poole, V., Seed, R. I., Sharma, N., Vicki Smith, Kwan, P. P. K., Stewart, S. L., Bacon, A., Warfield, A., Jayne Franklyn, Christopher McCabe & Kristien Boelaert, 18 Jul 2013, In : Endocrinology.

    Research output: Contribution to journalArticle

  58. Published
  59. Published
  60. Published
  61. 2012
  62. Published

    TSHR is the main causative locus in autosomal recessively inherited thyroid dysgenesis

    Cangul, H., Aycan, Z., Saglam, H., Forman, J. R., Cetinkaya, S., Tarim, O., Bober, E., Cesur, Y., Kurtoglu, S., Darendeliler, F., Bas, V., Eren, E., Demir, K., Kiraz, A., Aydin, B. K., Karthikeyan, A., Kendall, M., Boelaert, K., Shaw, N. J., Kirk, J. & 3 others, Hogler, W., Timothy Barrett & Eamonn Maher, Jun 2012, In : Journal of pediatric endocrinology & metabolism. 25, 5-6, p. 419-426 8 p.

    Research output: Contribution to journalArticle

  63. Published

    The pituitary tumor transforming gene in thyroid cancer

    Lewy, GD., Neil Sharma, Seed, RI., Vicki Smith, Kristien Boelaert & Christopher McCabe, 5 Apr 2012, In : Journal of endocrinological investigation. 35, 4, p. 425-433

    Research output: Contribution to journalReview article

  64. Published

    Dietary factors augment the ability of the proto-oncogene PBF to induce goitrogenesis and hyperplasia in vivo

    Martin Read, Vicki Smith, Lewy, G., Ryan, G., Sharma, N., Seed, R., Jim Fong, Kwan, P., Warfield, A., Wendy Leadbeater, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Mar 2012, In : Endocrine Abstracts. 28, OC3.8.

    Research output: Contribution to journalAbstract

  65. Published

    Thyrotoxicosis

    Jayne Franklyn & Kristien Boelaert, 1 Mar 2012, In : Lancet. 379, 9821, p. 1155-1166 12 p.

    Research output: Contribution to journalArticle

  66. Published

    PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8

    Vicki Smith, Martin Read, Andrew Turnell, Sharma, N., Lewy, G. D., Jim Fong, Seed, R. I., Kwan, P., Ryan, G., Mehanna, H., Shiaoyng Chan, Darras, V. M., Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 2012, In : Endocrinology. 153, 7, p. 3526-36 11 p.

    Research output: Contribution to journalArticle

  67. 2011
  68. Published

    Choice of Antithythroid Drugs in Pregnancy Response

    Kristien Boelaert, 1 Oct 2011, In : Thyroid. 21, 10, p. 1160-1161 2 p.

    Research output: Contribution to journalArticle

  69. Published

    Finding the malignant thyroid nodule in the haystack

    Kristien Boelaert & Christopher McCabe, 1 Oct 2011, In : Nature Reviews Endocrinology. 7, 10, p. 563-564 2 p.

    Research output: Contribution to journalEditorial

  70. Published

    Proto-oncogene PBF/PTTG1IP Regulates Thyroid Cell Growth and Represses Radioiodide Treatment

    Martin Read, Lewy, G., Jim Fong, Neil Sharma, Seed, R., Vicki Smith, Gentilin, E., Warfield, A., Margaret Eggo, Knauf, JA., Wendy Leadbeater, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Oct 2011, In : Cancer Research. 71, 19, p. 6153-64 12 p.

    Research output: Contribution to journalArticle

  71. Published

    Iodine status of UK schoolgirls: a cross-sectional survey

    Vanderpump, MPJ., Lazarus, JH., Smyth, PP., Laurberg, P., Roger Holder, Kristien Boelaert & Jayne Franklyn, 1 Jun 2011, In : Lancet. 377, 9782, p. 2007-2012 6 p.

    Research output: Contribution to journalArticle

  72. Published

    PTTG-Binding Factor (PBF) induces goitrogenesis and represses iodide uptake in vivo

    Martin Read, Lewy, G., Neil Sharma, Jim Fong, Vicki Smith, Ryan, GA., Seed, RI., Kwan, PPK., Wendy Leadbeater, Warfield, A., Knauf, JA., Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2011.

    Research output: Contribution to conference (unpublished)Paper

  73. Published

    PTTG-Binding Factor (PBF) induces hyperplastic lesions in thyroids of aged mice

    Martin Read, Lewy, G., Neil Sharma, Jim Fong, Vicki Smith, Ryan, GA., Seed, RI., Kwan, PPK., Wendy Leadbeater, Warfield, A., Knauf, JA., Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2011.

    Research output: Contribution to conference (unpublished)Paper

  74. 2010
  75. Published
  76. Published

    The PTTG-Binding Factor (PBF) induces thyroid hyperplastic lesions in aged mice

    Martin Read, Lewy, G., Neil Sharma, Jim Fong, Vicki Smith, Seed, RI., Kwan, PPK., Ryan, GA., Wendy Leadbeater, Warfield, A., Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Oct 2010.

    Research output: Contribution to conference (unpublished)Abstract

  77. Published

    Thyroid hyperplasia in a transgenic mouse model of PTTG-Binding Factor (PBF) overexpression

    Martin Read, Lewy, G., Neil Sharma, Jim Fong, Vicki Smith, Seed, RI., Ryan, GA., Kwan, PP., Wendy Leadbeater, Warfield, A., Margaret Eggo, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Sep 2010.

    Research output: Contribution to conference (unpublished)Abstract

  78. Published

    Treatment of Graves' Disease with Antithyroid Drugs: Current Perspectives

    Kristien Boelaert, 1 Sep 2010, In : Thyroid. 20, 9, p. 943-946 4 p.

    Research output: Contribution to journalEditorial

  79. Published

    Who Should Treat Thyroid Cancer? A UK Surgical Perspective

    Neil Sharma, Kristien Boelaert & Watkinson, J., 1 Aug 2010, In : Clinical Oncology. 22, 6, p. 413-418 6 p.

    Research output: Contribution to journalArticle

  80. Published

    Pituitary Tumor Transforming Gene Binding Factor: A New Gene in Breast Cancer

    Rachel Spruce, Martin Read, Vicki Smith, Neil Sharma, Reynolds, G., Laura Buckley, Doig, C., Campbell, MJ., Lewy, G., Margaret Eggo, Laurence Loubiere, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 May 2010, In : Cancer Research. 70, 9, p. 3739-3749 11 p.

    Research output: Contribution to journalArticle

  81. Published
  82. Published

    Thyroid Gland: Revised Guidelines for the Management of Thyroid Cancer

    Kristien Boelaert, 1 Apr 2010, In : Nature Reviews Endocrinology. 6, 4, p. 185-186 2 p.

    Research output: Contribution to journalEditorial

  83. Published

    Prevalence and Relative Risk of Other Autoimmune Diseases in Subjects with Autoimmune Thyroid Disease

    Kristien Boelaert, Paul Newby, Matthew Simmonds, Roger Holder, Carr-Smith, J., Heward, JM., Manji, N., Allahabadia, A., Armitage, M., Chatterjee, KV., Lazarus, JH., Pearce, SH., Vaidya, B., Stephen Gough & Jayne Franklyn, 1 Feb 2010, In : The American Journal of Medicine. 123, 2, p. 183.e1 1 p.

    Research output: Contribution to journalArticle

  84. Published

    Akt activation in a murine thyroid goitre model induced by the tumourigenic factor PBF

    Martin Read, Lewy, G., Neil Sharma, Jim Fong, Vicki Smith, Seed, RI., Kwan, P., Wendy Leadbeater, Warfield, A., Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2010.

    Research output: Contribution to conference (unpublished)Paper

  85. Published
  86. 2009
  87. Published
  88. Published

    The association between serum TSH concentration and thyroid cancer

    Kristien Boelaert, 20 Jul 2009, In : Endocrine-related cancer.

    Research output: Contribution to journalArticle

  89. Published

    A role for PTTG binding factor (PBF) in goitrogenesis

    Martin Read, Lewy, G., Jim Fong, Vicki Smith, Seed, RI., Watkins, RJ., Warfield, A., Wendy Leadbeater, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2009.

    Research output: Contribution to conference (unpublished)Paper

  90. Published

    Enlargement of the thyroid gland in a heterozygous PBF knock-in transgenic mouse model

    Martin Read, Jim Fong, Lewy, G., Vicki Smith, Andrew Turnell, Watkins, RJ., Seed, R., Stewart, S., Warfield, A., Wendy Leadbeater, Dae Kim, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2009, p. 371. 1 p.

    Research output: Contribution to conference (unpublished)Paper

  91. Published

    Evidence of a role for the PTTG binding protein (PBF) in goitrogenesis

    Martin Read, Lewy, G., Jim Fong, Vicki Smith, Seed, RI., Watkins, RJ., Wendy Leadbeater, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2009.

    Research output: Contribution to conference (unpublished)Paper

  92. Published
  93. 2008
  94. Published
  95. 2007
  96. Published

    Separase, securin and Rad21 in neural cell growth

    Pemberton, H., Jayne Franklyn, Kristien Boelaert, Shiaoyng Chan, Dae Kim, Kim, C., Cheng, SY., Mark Kilby & Christopher McCabe, 1 Oct 2007, In : Journal of Cellular Physiology. 213, 1, p. 45-53 9 p.

    Research output: Contribution to journalArticle

  97. Published

    PTTG and PBF repress the human sodium iodide symporter

    Kristien Boelaert, Vicki Smith, Stratford, A., Kogai, T., Lesley Tannahill, Watkinson, J., Margaret Eggo, Jayne Franklyn & Christopher McCabe, 5 Feb 2007, In : Oncogene. 26, 30, p. 4344-4356 13 p.

    Research output: Contribution to journalArticle

  98. Published

    Age and gender differences and phenotypes of patients with autoimmune thyroid disease - The UK AITD Consortium

    Carr-Smith, J., Manji, N., Kristien Boelaert, Allahabadia, A., Armitage, M., Lazarus, J., Pearce, S., Viadja, B., Stephen Gough & Jayne Franklyn, 1 Jan 2007, p. P877.

    Research output: Contribution to conference (unpublished)Abstract

  99. Published

    The Sodium Iodide Symporter (NIS) is Repressed by PTTG via the Human NIS Upstream Enhancer (hNUE)

    Vicki Smith, Kristien Boelaert, Stratford, A., Sally James, Kogai, T., Jayne Franklyn & Christopher McCabe, 1 Jan 2007.

    Research output: Contribution to conference (unpublished)Abstract

  100. Published

    The assessment of thyroid neoplasia

    Kristien Boelaert, Jayne Franklyn, Michael Sheppard, Hay, I. & Wass, J., 1 Jan 2007, Clinical Endocrine Oncology.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  101. Published

    Using an increased fixed dose of 1311 (600MBq) leads to improved outcome in patients with hyperthyroidism

    Kristien Boelaert, Manji, N., Michael Sheppard, Stephen Gough & Jayne Franklyn, 1 Jan 2007, p. P312.

    Research output: Contribution to conference (unpublished)Abstract

  102. 2006
  103. Published

    Influences of age, gender, smoking and family history on autoimmune thyroid disease phentotype

    Manji, N., Carr-Smith, J., Kristien Boelaert, Allahabadia, A., Armitage, M., Chatterjee, VK., Lazarus, JH., Pearce, SHS., Vaidya, B., Stephen Gough & Jayne Franklyn, 26 Sep 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 12, p. 4873-4880 8 p.

    Research output: Contribution to journalArticle

  104. Published
  105. Published
  106. Published
  107. Published

    Influence of family history on the age of presentation of AITD - the UK AITD consortium

    Manji, N., Carr-Smith, J., Kristien Boelaert, Allahabadia, A., Armitage, M., Lazarus, J., Pearce, S., Viadja, B., Stephen Gough & Jayne Franklyn, 1 Jan 2006, p. P878.

    Research output: Contribution to conference (unpublished)Abstract

  108. Published

    PTTG binding factor (PBF) can transform cells independently of interaction with PTTG

    Stratford, A., Kristien Boelaert, Dae Kim, Jayne Franklyn & Christopher McCabe, 1 Jan 2006, p. P492.

    Research output: Contribution to conference (unpublished)Abstract

  109. Published
  110. Published

    RAD21 dependent effects of securin and separase on fetal neuronal cells

    Pemberton, H., Christopher McCabe, Kristien Boelaert, Dae Kim, Shiaoyng Chan, Jayne Franklyn & Mark Kilby, 1 Jan 2006.

    Research output: Contribution to conference (unpublished)Abstract

  111. Published

    RAD21-dependent effects of securin/PTTG and separase on fetal neuronal NT2 cells

    Pemberton, H., Kristien Boelaert, Dae Kim, Shiaoyng Chan, Mark Kilby, Jayne Franklyn & Christopher McCabe, 1 Jan 2006, p. P408.

    Research output: Contribution to conference (unpublished)Abstract

  112. Published

    Repression of the human NIS upstream enhancer (hNUE) by PTTG

    Vicki Smith, Kristien Boelaert, Stratford, A., Sally James, Susarla, R., Kogai, T., Margaret Eggo, Jayne Franklyn & Christopher McCabe, 1 Jan 2006, p. P906.

    Research output: Contribution to conference (unpublished)Abstract

  113. Published

    Repression of the human NIS upstream enhancer (hNUE) by PTTG and PBF

    Vicki Smith, Kristien Boelaert, Stratford, A., Sally James, Kogai, T., Jayne Franklyn & Christopher McCabe, 1 Jan 2006.

    Research output: Contribution to conference (unpublished)Abstract

  114. Published

    Repression of the human upsteam enhancer (hNUE) by TTG and PBF

    Vicki Smith, Kristien Boelaert, Stratford, A., Sally James, Kogai, T., Jayne Franklyn & Christopher McCabe, 1 Jan 2006, p. P16.

    Research output: Contribution to conference (unpublished)Abstract

  115. Published

    The sodium iodide symporter (NIS) is repressed by PTTG via the human NIS upsteam enhancer (hNUE)

    Vicki Smith, Kristien Boelaert, Stratford, A., Sally James, Susarla, R., Kogai, T., Margaret Eggo, Jayne Franklyn & Christopher McCabe, 1 Jan 2006, p. P489.

    Research output: Contribution to conference (unpublished)Abstract

  116. 2005
  117. Published
  118. Published

    Starling's Review: Thyroid hormone in health and disease

    Kristien Boelaert & Jayne Franklyn, 1 Oct 2005, In : Journal of Endocrinology. 187, 1, p. 1-15 15 p.

    Research output: Contribution to journalReview article

  119. Published

    Pituitary Tumor Transforming Gene (PTTG) Induces Genetic Instability in Thyroid Cells

    Dae Kim, Pemberton, H., Stratford, A., Kristien Boelaert, Watkinson, J., Victor Lopes, Jayne Franklyn & Christopher McCabe, 9 May 2005, In : Oncogene. 24(30), p. 4861-4866 6 p.

    Research output: Contribution to journalArticle

  120. Published
  121. Published

    Gene regulation by the c-terminal PXXP motif of PTTG

    Gokce, C., Lesley Tannahill, Stratford, A., Farhat Khanim, Pemberton, H., Dae Kim, Neil Gittoes, Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 1 Jan 2005, p. P148.

    Research output: Contribution to conference (unpublished)Abstract

  122. Published

    PTTG Induces Genomic Instability in Thyroid Cells

    Dae Kim, Kristien Boelaert, Pemberton, H., Stratford, A., Watkinson, J., Jayne Franklyn & Christopher McCabe, 1 Jan 2005.

    Research output: Contribution to conference (unpublished)Paper

  123. Published

    PTTG and PBF in human placenta: the effects of IUGR

    Kristien Boelaert, Pemberton, H., Bulmer, JN., Christopher McCabe, Jayne Franklyn & Mark Kilby, 1 Jan 2005, p. P60.

    Research output: Contribution to conference (unpublished)Abstract

  124. Published

    PTTG and PBF in human placenta: the effects of intra-uterine growth restriction

    Kristien Boelaert, Pemberton, H., Bulmer, JN., Christopher McCabe, Jayne Franklyn & Mark Kilby, 1 Jan 2005.

    Research output: Contribution to conference (unpublished)Paper

  125. Published
  126. Published

    PTTG induces genomic instability in thyroid cells

    Dae Kim, Stratford, A., Kristien Boelaert, Pemberton, H., Gocke, C., Margaret Eggo, Lesley Tannahill, Watkinson, J., Jayne Franklyn & Christopher McCabe, 1 Jan 2005, p. OC36.

    Research output: Contribution to conference (unpublished)Abstract

  127. Published

    Separase and Securin; Their Roles in the Developing Human Fetal Brain

    Pemberton, H., Kristien Boelaert, Mark Kilby, Jayne Franklyn & Christopher McCabe, 1 Jan 2005, p. P62.

    Research output: Contribution to conference (unpublished)Abstract

  128. Published

    Separase and Securin; Their Roles in the Developing Human Fetal Brain

    Pemberton, H., Kristien Boelaert, Mark Kilby, Jayne Franklyn & Christopher McCabe, 1 Jan 2005.

    Research output: Contribution to conference (unpublished)Paper

  129. Published

    Separase and securing; their roles in the developing human fetal brain

    Pemberton, H., Kristien Boelaert, Mark Kilby, Jayne Franklyn & Christopher McCabe, 1 Jan 2005, p. P62.

    Research output: Contribution to conference (unpublished)Abstract

  130. 2004
  131. Published

    Gender, age, goitre type and sereum TSH predict thyroid neoplasia in 1500 patients with thyroid enlargement investigated by FNAC

    Kristien Boelaert, Horacek, Y., Daykin, J., Michael Sheppard & Jayne Franklyn, 1 Jan 2004, p. OC21.

    Research output: Contribution to conference (unpublished)Abstract

  132. Published

    Human PTTG expression in normal and growth restricted placentae

    Kristien Boelaert, Bulmer, JN., Shiaoyng Chan, Neil Gittoes, Christopher McCabe, Jayne Franklyn & Mark Kilby, 1 Jan 2004, p. P3-348.

    Research output: Contribution to conference (unpublished)Abstract

  133. Published
  134. Published

    PBF predicts recurrence in thyroid cancer and potentiates the actions of PTTG in vitro

    Stratford, AL., Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 1 Jan 2004, p. OC19.

    Research output: Contribution to conference (unpublished)Abstract

  135. Published
  136. Published

    PTTG expression and genomic instability in differentiated thyroid cancer using the FISSR-PCR technique

    Dae Kim, Christopher McCabe, Kristien Boelaert, Pemberton, H., Stratford, A., Watkinson, J. & Jayne Franklyn, 1 Jan 2004.

    Research output: Contribution to conference (unpublished)Paper

  137. Published

    PTTG regulates downstream angiogenic genes in thyroid cells

    Dae Kim, Kristien Boelaert, Stratford, A., Margaret Eggo, Watkinson, J., Neil Gittoes, Jayne Franklyn & Christopher McCabe, 1 Jan 2004, p. P100.

    Research output: Contribution to conference (unpublished)Abstract

  138. Published

    PTTG regulates the associated molecule with the SH3 domain of STAM (AMSH) via its C-terminal PXXP motif

    Gokce, C., Lesley Tannahill, Stratford, A., Farhat Khanim, Pemberton, H., Dae Kim, Neil Gittoes, Kristien Boelaert, Christopher McCabe & Jayne Franklyn, 1 Jan 2004.

    Research output: Contribution to conference (unpublished)Paper

  139. Published
  140. Published

    Pituitary tumor transforming gene (PTTG) regulates downsteam angiogenic genes in thyroid cells

    Dae Kim, Kristien Boelaert, Stratford, A., Margaret Eggo, Neil Gittoes, Jayne Franklyn & Christopher McCabe, 1 Jan 2004, p. P3-219.

    Research output: Contribution to conference (unpublished)Abstract

  141. Published

    Pituitary tumor transforming gene (PTTG) regulates downstream angiogenic genes in thyroid cells

    Dae Kim, Kristien Boelaert, Stratford, A., Margaret Eggo, Neil Gittoes, Jayne Franklyn & Christopher McCabe, 1 Jan 2004, p. 100. 1 p.

    Research output: Contribution to conference (unpublished)Abstract

  142. Published

    Relationship between PTTG expression and genomic instability in differentiated thyroid cancers

    Dae Kim, Kristien Boelaert, Stratford, A., Watkinson, J., Jayne Franklyn & Christopher McCabe, 1 Jan 2004.

    Research output: Contribution to conference (unpublished)Paper

  143. Published
  144. Published
  145. Published

    The key mitotic regulators securin and separase in the human fetal brain

    Pemberton, H., Kristien Boelaert, Dae Kim, Lesley Tannahill, Farhat Khanim, Neil Gittoes, Jayne Franklyn, Mark Kilby & Christopher McCabe, 1 Jan 2004, p. P3-350.

    Research output: Contribution to conference (unpublished)Abstract

  146. 2003
  147. Published
  148. Published
  149. Published
  150. Published
  151. Published

    Sodium iodide symporter: a novel strategy to target breast, prostate, and other cancers?

    Kristien Boelaert & Jayne Franklyn, 8 Mar 2003, In : Lancet. 361, 9360, p. 796-797 2 p.

    Research output: Contribution to journalReview article

  152. Published
  153. Published

    A potential role for human securin/PTTG in the developing fetal brain

    Kristien Boelaert, Christopher McCabe, Lesley Tannahill, Bulmer, JN., Chan, S., Neil Gittoes, Michael Sheppard, Mark Kilby & Jayne Franklyn, 1 Jan 2003, p. P164.

    Research output: Contribution to conference (unpublished)Abstract

  154. Published

    A potential role for human securin/PTTG in the developing human fetal brain

    Kristien Boelaert, Christopher McCabe, Lesley Tannahill, Bulmer, JN., Shiaoyng Chan, Neil Gittoes, Mark Kilby & Jayne Franklyn, 1 Jan 2003, p. 164. 1 p.

    Research output: Contribution to conference (unpublished)Abstract

  155. Published
  156. Published

    PTTG binding factor in thyroid cancer

    Stratford, A., Kristien Boelaert, Farhat Khanim, Dae Kim & Jayne Franklyn, 1 Jan 2003, p. 93. 1 p.

    Research output: Contribution to conference (unpublished)Abstract

  157. Published

    PTTG upregulates its binding factor PBF in vitro

    Stratford, A., Farhat Khanim, Kristien Boelaert, Neil Gittoes, Jayne Franklyn & Christopher McCabe, 1 Jan 2003, p. P131.

    Research output: Contribution to conference (unpublished)Abstract

  158. Published
  159. Published
  160. 2002
  161. Published
  162. Published
  163. Published
  164. Published
  165. Published

    Expression and function of VEGF and its receptor KDR in pituitary tumors

    Christopher McCabe, Kristien Boelaert, Lesley Tannahill, McRobbie, L. J., Hussain, S., Michael Sheppard, Neil Gittoes & Jayne Franklyn, 1 Jan 2002, p. P2-231.

    Research output: Contribution to conference (unpublished)Paper

  166. Published

    Expression and function of VEGF and its receptor in pituitary tumours

    Christopher McCabe, Kristien Boelaert, Lesley Tannahill, Jattinder Khaira, McRobbie, L. J., Hussain, S., Michael Sheppard, Neil Gittoes & Jayne Franklyn, 1 Jan 2002, p. OC14.

    Research output: Contribution to conference (unpublished)Paper

  167. Published
  168. Published
  169. Published

    PTTG and FGF-2 -novel potential molecular indicators for thyroid cancer

    Kristien Boelaert, Christopher McCabe, Lesley Tannahill, Neil Gittoes, Watkinson, J., Michael Sheppard & Jayne Franklyn, 1 Jan 2002, p. OR 61-62.

    Research output: Contribution to conference (unpublished)Paper

  170. Published
  171. Published

    The destruction box PTTG mediates cell transformation

    Christopher McCabe, Horwitz, GA., Lesley Tannahill, Kristien Boelaert, Yu, R., McRobbie, L. J., Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Jan 2002, p. P139.

    Research output: Contribution to conference (unpublished)Paper

  172. 2001
  173. Published

    Radiotherapy for non-functioning pituitary tumours

    Kristien Boelaert & Neil Gittoes, 1 Jun 2001, In : European Journal of Endocrinology. 144, 6, p. 569-575 7 p.

    Research output: Contribution to journalReview article

  174. Published

    Deiodinase activity and expression in the early human fetal brain

    Kachilele-Linjewile Kachilele, Christopher McCabe, Kristien Boelaert, Lesley Tannahill, Visser, TJ., Chan, S., Neil Gittoes, Jayne Franklyn & Mark Kilby, 1 Jan 2001, p. 176. 1 p.

    Research output: Contribution to conference (unpublished)Abstract

  175. Published
  176. Published
  177. Published

    Deiodinase expression in human placenta as a function of gestational age: the effects of intrauterine growth restriction (IUGR)

    Kachilele-Linjewile Kachilele, Christopher McCabe, Kristien Boelaert, Lesley Tannahill, Neil Gittoes, Jayne Franklyn & Mark Kilby, 1 Jan 2001, Proceedings of the 83rd Meeting of the American Endocrine Society. p. 3-27 25 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  178. Published
  179. Published
  180. Published
  181. Published

    Pituitary tumor transforming gene (PTTG) and thyroid disease

    Kristien Boelaert, Christopher McCabe, Jattinder Khaira, Neil Gittoes, Margaret Eggo, Watkinson, J., Michael Sheppard & Jayne Franklyn, 1 Jan 2001, p. 1-215. 215 p.

    Research output: Contribution to conference (unpublished)Paper

  182. Published
  183. Published
  184. Published