Kristien Boelaert

A high-throughput yellow fluorescent protein (YFP) cell-based screen identifies autophagy modulators to increase the effectiveness of radioiodine therapy

Martin Read, Brookes, K., Alice Fletcher, Thornton, C., Alshahrani, M., Nieto, H., Khan, R., Webster, J., Haggie, P., Verkman, A., Luke Alderwick, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 Nov 2019, In : Endocrine Abstracts. 65, 1 p., OC4.1.

Research output: Contribution to journal › Abstract

Targeting novel sodium iodide symporter interactors ADP-ribosylation factor 4 (ARF4) and valosin-containing protein (VCP) enhances radioiodine uptake: Targeting NIS interactors to enhance radioiodine uptake

Alice Fletcher, Martin Read, Thornton, C., Dean Larner, Poole, V., Brookes, K., Hannah Nieto, Alshahrani, M., Thompson, R., Gareth Lavery, Landa, I., Fagin, J. A., Campbell, M. J., Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 31 Oct 2019, In : Cancer Research.

Research output: Contribution to journal › Article

Patients treated for hyperthyroidism are at increased risk of becoming obese: findings from a large prospective secondary care cohort

Barbara Torlinska, Nichols, L., Mohammed, M. A., McCabe, C. & Kristien Boelaert, 15 Oct 2019, In : Thyroid. 29, 10, p. 1380-1389 10 p.

Research output: Contribution to journal › Article

Dimerization of the sodium/iodide symporter

Thompson, R. J., Alice Fletcher, Brookes, K., Nieto, H., Alshahrani, M. M., Jonathan Wolf Mueller, Fine, N. H. F., David Hodson, Kristien Boelaert, Martin Read, Vicki Smith & Christopher McCabe, Oct 2019, In : Thyroid. 29, 10, p. 1485-1498 14 p.

Research output: Contribution to journal › Article

Thyroid replacement therapy, thyroid stimulating hormone levels and long-term health outcomes in patients with hypothyroidism: a longitudinal study

Rasiah Thayakaran, Nicola Adderley, Sainsbury, C., Barbara Torlinska, Kristien Boelaert, Dana Sumilo, Malcolm Price, G Neil Thomas, Toulis, K. & Krishnarajah Nirantharakumar, 3 Sep 2019, In : BMJ. 366, l4892.

Research output: Contribution to journal › Article

Risk of incident circulatory disease in patients treated for differentiated thyroid carcinoma with no history of cardiovascular disease

Toulis, K. A., Viola, D., Gkoutos, G., Keerthy, D., Kristien Boelaert & Krishnarajah Nirantharakumar, 1 Aug 2019, In : Clinical Endocrinology. 91, 2, p. 323-330 8 p.

Research output: Contribution to journal › Article

Antigen-specific immunotherapy with thyrotropin receptor peptides in Graves' hyperthyroidism: a phase I study

Pearce, S. H. S., Dayan, C., Wraith, D. C., Barrell, K., Olive, N., Jansson, L., Walker-Smith, T., Carnegie, C., Martin, K. F., Kristien Boelaert, Gilbert, J., Higham, C. E., Muller, I., Murray, R. D., Perros, P., Razvi, S., Vaidya, B., Wernig, F. & Kahaly, G. J., 17 Jul 2019, In : Thyroid. 29, 7, p. 1003-1011 9 p.

Research output: Contribution to journal › Article

Glucocorticoid induced adrenal insufficiency is common in steroid treated glomerular diseases - proposed strategy for screening and management

Karangizi, A. H. K., Al-Shaghana, M., Logan, S., Criseno, S., Webster, R., Kristien Boelaert, Hewins, P. & Lorraine Harper, 6 May 2019, In : BMC Nephrology. 20, 1, 154.

Research output: Contribution to journal › Article

Levothyroxine in Women with Thyroid Peroxidase Antibodies before Conception

Dhillon-smith, R., Middleton, L., Sunner, K., Cheed, V., Baker, K., Farrell-Carver, S., Bender Atik, R., Agrawal, R., Bhatia, K., Edi-Osagie, E., Ghobara, T., Gupta, P., Jurkovic, D., Khalaf, Y., MacLean, M., McCabe, C., Mulbagal, K., Nunes, N., Overton, C., Quenby, S. & 14 others, Rai, R., Raine-Fenning, N., Robinson, L., Ross, J., Sizer, A., Small, R., Alex Tan, Underwood, M., Mark Kilby, Kristien Boelaert, Jane Daniels, Shakila Thangaratinam, Chan, S. Y. & Coomarasamy, A., 4 Apr 2019, In : The New England Journal of Medicine. 380, p. 1316-1325

Research output: Contribution to journal › Article

Knowledge of thyroid eye disease in Graves’ Disease patients with and without orbitopathy

Matthew Edmunds & Kristien Boelaert, 28 Jan 2019, In : Thyroid.

Research output: Contribution to journal › Article

Adjuvant rituximab, a potential treatment for the young patient with Graves' hyperthyroidism (RiGD): study protocol for a single-arm, single-stage, phase II trial

Cole, M., Hynes, A. M., Howel, D., Hall, L., Abinun, M., Allahabadia, A., Barrett, T., Kristien Boelaert, Drake, A. J., Dimitri, P., Kirk, J., Zammitt, N., Pearce, S. & Cheetham, T., 21 Jan 2019, In : BMJ open. 9, 1, 10 p., e024705.

Research output: Contribution to journal › Article

Liothyronine cost and prescriptions in England

Taylor, P. N., Razvi, S., Muller, I., Wass, J., Dayan, C. M., Chatterjee, K. & Kristien Boelaert, 1 Jan 2019, In : The Lancet Diabetes and Endocrinology. 7, 1, p. 11-12 2 p.

Research output: Contribution to journal › Letter

Biochemical analysis of radioiodine uptake enhancement in endocrine cancer

Alshahrani, M., Alice Fletcher, Thornton, C., Brookes, K., Hannah Nieto, Thompson, R., Martin Read, Kristien Boelaert, Christopher McCabe & Vicki Smith, 1 Nov 2018, In : Endocrine Abstracts. 59, 1 p., OC2.4.

Research output: Contribution to journal › Article

Oncogenic action of pituitary-tumor transforming gene (PBF) in head and neck cancer is associated with poorer overall survival

Martin Read, Modasia, B., Alice Fletcher, Thompson, R., Brookes, K., Hannah Nieto, Moray Campbell, Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 1 Nov 2018, In : Endocrine Abstracts. 59, 1 p., P119.

Research output: Contribution to journal › Abstract

Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism

Cangul, H., Liao, X., Schoenmakers, E., Kero, J., Barone, S., Srichomkwun, P., Iwayama, H., Serra, E. G., Saglam, H., Eren, E., Tarim, O., Nicholas, A. K., Zvetkova, I., Anderson, C. A., Frankl, F. E. K., Boelaert, K., Ojaniemi, M., Jääskeläinen, J., Patyra, K., Löf, C. & 7 others, Williams, E. D., Soleimani, M., Timothy Barrett, Eamonn Maher, Chatterjee, V. K., Refetoff, S. & Schoenmakers, N., 18 Oct 2018, In : JCI Insight. 3, 20, 11 p., e99631.

Research output: Contribution to journal › Abstract

PTTG and PBF functionally interact with p53 and predict overall survival in head and neck cancer

Martin Read, Modasia, B., Alice Fletcher, Thompson, R., Brookes, K., Peter Rae, Hannah Nieto, Poole, V., Sally Roberts, Moray Campbell, Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 28 Aug 2018, In : Cancer Research. 25 p.

Research output: Contribution to journal › Article

PO-124 PTTG and PBF functionally interact with P53 and predict overall survival in head and neck cancer

Martin Read, Modasia, B., Alice Fletcher, Thompson, R., Baker, K., Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 1 Jul 2018, In : ESMO Open. 3, Suppl. 2, p. A69-A69 1 p.

Research output: Contribution to journal › Abstract

The Clinical Utility of Cell-Free DNA Measurement in Differentiated Thyroid Cancer: A Systematic Review

Fussey, J. M., Jennifer Bryant, Nikos Batis, Rachel Spruce, Hartley, A., Good, J. S., Christopher McCabe, Kristien Boelaert, Neil Sharma & Hisham Mehanna, 30 Apr 2018, In : Frontiers in Oncology. 8, APR, 132.

Research output: Contribution to journal › Article

Iodine Status during Pregnancy in a Region of Mild-to-Moderate Iodine Deficiency is not Associated with Adverse Obstetric Outcomes; Results from the Avon Longitudinal Study of Parents and Children (ALSPAC)

Barbara Torlinska, Bath, S. C., Janjua, A., Kristien Boelaert & Chan, S-Y., 1 Mar 2018, In : Nutrients. 10, 3, 291.

Research output: Contribution to journal › Article

Functional consequences of the first reported mutations of the proto-oncogene PTTG1IP/PBF

Imruetaicharoenchoke, W., Alice Fletcher, Wenqi Lu, Watkins, RJ., Modasia, B., Poole, V., Hannah Nieto, Thompson, R., Kristien Boelaert, Martin Read, Vicki Smith & Christopher McCabe, Sep 2017, In : Endocrine-related cancer. 24, 9, p. 459-474

Research output: Contribution to journal › Article

MANAGEMENT OF ENDOCRINE DISEASE: Subclinical thyrotoxicosis: prevalence, causes and choice of therapy

Carlé, A., Andersen, S. L., Kristien Boelaert & Laurberg, P., Jun 2017, In : European Journal of Endocrinology. 176, 6, p. R325-R337

Research output: Contribution to journal › Review article

Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer

Martin Read, Fong, J., Modasia, B., Alice Fletcher, Imruetaicharoenchoke, W., Thompson, R., Hannah Nieto, John Reynolds, Bacon, A., Mallick, U., Hackshaw, A., Watkinson, J., Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 15 May 2017, In : Oncogene. 72326.

Research output: Contribution to journal › Article

Comparative analysis of human and mouse expression data identifies proto-oncogene PTTG- and PBF-associated genes in thyroid cancer

Martin Read, Fong, J., Imruetaicharoenchoke, W., Modasia, B., Hannah Nieto, Alice Fletcher, Thompson, R., Neil Sharma, Watkinson, J., Andrew Turnell, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 Feb 2017, In : Thyroid Research. 10(Suppl 1), 2

Research output: Contribution to journal › Abstract

Controlled Antenatal Thyroid Study: Obstetric Outcomes

Taylor, P., Lacey, A., Thayer, D., Yusof, M., Tabasum, A., Muller, I., Marsh, L., Ludgate, M., Rees, A., Kristien Boelaert, Shiaoyng Chan, Nelson, S., Rees, A., Lazarus, J., Dayan, C., Vaidya, B. & Okosieme, O., 13 Feb 2017, In : Thyroid Research. 10(Suppl 1), 2, p. 2 1 p., O1.

Research output: Contribution to journal › Abstract

Pharmacological enhancement of radioiodine uptake using Src kinase inhibitors

Poole, V., Alice Fletcher, Modasia, B., Neil Sharma, Thompson, R., Imruetaicharoenchoke, W., Martin Read, Kristien Boelaert, Christopher McCabe & Vicki Smith, 13 Feb 2017, In : Thyroid Research. 10(Suppl 1), 2, p. 2 1 p., O2.

Research output: Contribution to journal › Abstract

Pro-invasive effect of proto-oncogene PBF is modulated by an interaction with cortactin

Rachel Spruce, Imruetaicharoenchoke, W., Martin Read, Neil Sharma, Poole, V. L., Gentillin, E., Bansal, S., Bosseboeuf, E., Rachel Fletcher, Nieto, H. R., Mallick, U., Hackshaw, A., Hisham Mehanna, Kristien Boelaert, Vicki Smith & Christopher McCabe, Dec 2016, In : The Journal of clinical endocrinology and metabolism. 101, 12, p. 4551-4563

Research output: Contribution to journal › Article

High tumoral expression of PBF and PTTG modulates the DNA damage response and is associated with poor survival in thyroid cancer

Martin Read, Jim Fong, Imruetaicharoenchoke, W., Nieto, H., Modasia, B., Alice Fletcher, Thompson, R., Neil Sharma, Bacon, A., Watkinson, J., Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 4 Nov 2016, In : Endocrine Abstracts. 44, P246.

Research output: Contribution to journal › Abstract

Thyroid stimulating hormone in thyroid cancer: does it matter?

Hannah Nieto & Kristien Boelaert, 1 Nov 2016, In : Endocrine-related cancer. 23, 11, ERC-16-0328.

Research output: Contribution to journal › Article

Multifocality in Sporadic Medullary Thyroid Carcinoma: An International Multicenter Study

Essig, G. F., Porter, K., Schneider, D., Arpaia, D., Lindsey, S. C., Busonero, G., Fineberg, D., Fruci, B., Boelaert, K., Smit, J. W., Meijer, J. A. A., Duntas, L. H., Sharma, N., Costante, G., Filetti, S., Sippel, R. S., Biondi, B., Topliss, D. J., Pacini, F., Maciel, R. M. B. & 2 others, Walz, P. C. & Kloos, R. T., Nov 2016, In : Thyroid. 26, 11, p. 1563-1572 10 p.

Research output: Contribution to journal › Article

WOMEN IN CANCER PROFILE: From bedside to bench and back: my journey in thyroid disease

Kristien Boelaert, Nov 2016, In : Endocrine-related cancer. 23, 11, p. 9-13

Research output: Contribution to journal › Special issue

Comparative analysis of human and mouse expression data identifies distinct proto-oncogene PBF- and PTTG-associated genes in thyroid cancer

Martin Read, Jim Fong, Imruetaicharoenchoke, W., Modasia, B., Hannah Nieto, Watkinson, J., Kristien Boelaert, Vicki Smith, Andrew Turnell & Christopher McCabe, 1 Jul 2016, In : European Journal of Cancer. 61, Suppl 1, p. S36 1 p., 202.

Research output: Contribution to journal › Abstract

The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer

Martin Read, Seed, R. I., Modasia, B., Kwan, P. P. K., Sharma, N., Vicki Smith, Rachel Spruce, Bansal, S., Gagliano, T., Stratford, A. L., Ismail, T., Wakelam, M. J. O., Dae Kim, Stephen Ward, Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Jan 2016, In : Molecular Carcinogenesis. 55, 1, p. 15-26

Research output: Contribution to journal › Article

Distinct p53 response profiles in transgenic mouse models of thyroid-specific PBF and PTTG expression

Martin Read, Fong, J., Imruetaicharoenchoke, W., Modasia, B., Lewy, G., Ryan, G., Neil Sharma, Vicki Smith, Watkinson, J., Kristien Boelaert & Christopher McCabe, Nov 2015, In : Endocrine Abstracts. 38, P149.

Research output: Contribution to journal › Abstract

Effectiveness of metyrapone in treating Cushing's Syndrome: a retrospective multicenter study in 195 patients

Daniel, E., Aylwin, S., Mustafa, O., Ball, S., Munir, A., Boelaert, K., Chortis, V., Cuthbertson, D. J., Daousi, C., Rajeev, S. P., Davis, J., Cheer, K., Drake, W., Gunganah, K., Grossman, A., Gurnell, M., Powlson, A. S., Karavitaki, N., Huguet, I., Kearney, T. & 8 others, Mohit, K., Meeran, K., Hill, N., Rees, A., Lansdown, A. J., Trainer, P. J., Minder, A-E. H. & Newell-Price, J., 9 Sep 2015, In : The Journal of clinical endocrinology and metabolism. 100, 11, jc20152616.

Research output: Contribution to journal › Article

Costs and benefits of iodine supplementation for pregnant women in a mildly to moderately iodine-deficient population: a modelling analysis

Mark Monahan, Kristien Boelaert, Kate Jolly, Shiaoyng Chan, Pelham Barton & Tracy Roberts, Sep 2015, In : The Lancet Diabetes and Endocrinology. 3, 9, p. 715-722 8 p.

Research output: Contribution to journal › Article

Management of primary hypothyroidism: statement by the British Thyroid Association Executive Committee

Okosieme, O., Gilbert, J., Abraham, P., Kristien Boelaert, Dayan, C., Gurnell, M., Leese, G., Christopher McCabe, Perros, P., Vicki Smith, Williams, G. & Vanderpump, M., 23 May 2015, In : Clinical Endocrinology.

Research output: Contribution to journal › Article

Clinical challenges of thyroid eye disease in HIV-positive patients on highly active antiretroviral therapy

Matthew Edmunds, Mellington, F., Ford, R. L., Barbara Torlinska, Manavi, K. & Kristien Boelaert, Mar 2015, In : The Journal of clinical endocrinology and metabolism. 100, 3, p. 779-787 9 p.

Research output: Contribution to journal › Article

Autoimmune encephalopathy in the context of Graves' disease with ophthalmopathy

Vasileios Chortis, Matthew Edmunds, Littleton, E. T. & Kristien Boelaert, Dec 2014, In : Clinical Endocrinology. 81, 6, p. 936-7 2 p.

Research output: Contribution to journal › Article

One Base Deletion (c.2422delT) in the TPO Gene Causes Severe Congenital Hypothyroidism

Cangul, H., Kristien Boelaert, Timothy Barrett, Dogan, M., Saglam, Y., Kendall, M. & Maher, E., 5 Sep 2014, In : J Clin res Pediatr Endocrinol. 6, 3, p. 169-73

Research output: Contribution to journal › Article

Differences in the recurrence and mortality outcomes rates of incidental and nonincidental papillary thyroid microcarcinoma: a systematic review and meta-analysis of 21 329 person-years of follow-up

Hisham Mehanna, Al-Maqbili, T., Ben Carter, Martin, E., Campain, N., Watkinson, J., McCabe, C., Kristien Boelaert & Jayne Franklyn, Aug 2014, In : The Journal of clinical endocrinology and metabolism. 99, 8, p. 2834-43 10 p.

Research output: Contribution to journal › Article

The PTTG1-binding factor (PBF/PTTG1IP) regulates p53 activity in thyroid cells

Martin Read, Seed, R. I., Jim Fong, Modasia, B., Ryan, G. A., Rachel Spruce, Gagliano, T., Vicki Smith, Stratford, A. L., Kwan, P. K., Neil Sharma, Dixon, O. M., Watkinson, J. C., Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Apr 2014, In : Endocrinology. 155, 4, p. 1222-34 13 p.

Research output: Contribution to journal › Article

Examination of PTTG-Binding Factor (PBF) mRNA reveals functional miRNA target sites and exon-skipping splice variants in thyroid cells

Martin Read, Longman, J., Alice Fletcher, Vicki Smith, Rachel Spruce, Modasia, B., Poole, V., Imruetaicharoenchoke, W., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Mar 2014, In : Endocrine Abstracts. 34, P397.

Research output: Contribution to journal › Abstract

Patient information in Graves' disease and thyroid-associated ophthalmopathy: readability assessment of online resources

Matthew Edmunds, Alastair Denniston, Kristien Boelaert, Jayne Franklyn & Omar Durrani, Jan 2014, In : Thyroid. 24, 1, p. 67-72 6 p.

Research output: Contribution to journal › Article

Fine needle aspiration and medulla

Essig, G., Porter, K., Schneider, D., Debora, A., Lindsey, S., Busonero, G., Fineberg, D., Fruci, B., Boelaert, K., Smit, J., Meijer, J., Duntas, L., Sharma, N., Costante, G., Filetti, S., Sippel, R., Biondi, B., Topliss, D., Pacini, F., MacIel, R. & 2 others, Walz, P. & Kloos, R., 1 Nov 2013, In : Endocrine Practice. 19, 6, p. 920-927 8 p.

Research output: Contribution to journal › Article

Thyroid dyshormonogenesis is mainly caused by TPO mutations in consanguineous community

Cangul, H., Aycan, Z., Olivera-Nappa, A., Saglam, H., Schoenmakers, N. A., Kristien Boelaert, Cetinkaya, S., Tarim, O., Bober, E., Darendeliler, F., Bas, V., Demir, K., Aydin, B. K., Kendall, M., Cole, T., Högler, W., Chatterjee, V. K. K., Timothy Barrett & Eamonn Maher, Aug 2013, In : Clinical Endocrinology. 79, 2, p. 275-81 7 p.

Research output: Contribution to journal › Article

Regulation of Pituitary Tumor Transforming Gene (PTTG) expression and phosphorylation in thyroid cells

Lewy, G. D., Ryan, G. A., Martin Read, Jim Fong, Poole, V., Seed, R. I., Sharma, N., Vicki Smith, Kwan, P. P. K., Stewart, S. L., Bacon, A., Warfield, A., Jayne Franklyn, Christopher McCabe & Kristien Boelaert, 18 Jul 2013, In : Endocrinology.

Research output: Contribution to journal › Article

Manipulation of PBF/PTTG1IP phosphorylation status ; a potential new therapeutic strategy for improving radioiodine uptake in thyroid and other tumors

Vicki Smith, Neil Sharma, Rachel Spruce, Martin Read, Ryan, G., Kwan, P., Ashley Martin, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jul 2013, In : The Journal of clinical endocrinology and metabolism. 98, 7, p. 2876-2886 11 p.

Research output: Contribution to journal › Article

Comparison of mortality in hyperthyroidism during periods of treatment with thionamides and after radioiodine

Kristien Boelaert, Maisonneuve, P., Barbara Torlinska & Jayne Franklyn, May 2013, In : The Journal of clinical endocrinology and metabolism. 98, 5, p. 1869-82 14 p.

Research output: Contribution to journal › Article

TSHR is the main causative locus in autosomal recessively inherited thyroid dysgenesis

Cangul, H., Aycan, Z., Saglam, H., Forman, J. R., Cetinkaya, S., Tarim, O., Bober, E., Cesur, Y., Kurtoglu, S., Darendeliler, F., Bas, V., Eren, E., Demir, K., Kiraz, A., Aydin, B. K., Karthikeyan, A., Kendall, M., Boelaert, K., Shaw, N. J., Kirk, J. & 3 others, Hogler, W., Timothy Barrett & Eamonn Maher, Jun 2012, In : Journal of pediatric endocrinology & metabolism. 25, 5-6, p. 419-426 8 p.

Research output: Contribution to journal › Article

The pituitary tumor transforming gene in thyroid cancer

Lewy, GD., Neil Sharma, Seed, RI., Vicki Smith, Kristien Boelaert & Christopher McCabe, 5 Apr 2012, In : Journal of endocrinological investigation. 35, 4, p. 425-433

Research output: Contribution to journal › Review article

Dietary factors augment the ability of the proto-oncogene PBF to induce goitrogenesis and hyperplasia in vivo

Martin Read, Vicki Smith, Lewy, G., Ryan, G., Sharma, N., Seed, R., Jim Fong, Kwan, P., Warfield, A., Wendy Leadbeater, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Mar 2012, In : Endocrine Abstracts. 28, OC3.8.

Research output: Contribution to journal › Abstract

Thyrotoxicosis

Jayne Franklyn & Kristien Boelaert, 1 Mar 2012, In : Lancet. 379, 9821, p. 1155-1166 12 p.

Research output: Contribution to journal › Article

PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8

Vicki Smith, Martin Read, Andrew Turnell, Sharma, N., Lewy, G. D., Jim Fong, Seed, R. I., Kwan, P., Ryan, G., Mehanna, H., Shiaoyng Chan, Darras, V. M., Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 2012, In : Endocrinology. 153, 7, p. 3526-36 11 p.

Research output: Contribution to journal › Article

Choice of Antithythroid Drugs in Pregnancy Response

Kristien Boelaert, 1 Oct 2011, In : Thyroid. 21, 10, p. 1160-1161 2 p.

Research output: Contribution to journal › Article

Finding the malignant thyroid nodule in the haystack

Kristien Boelaert & Christopher McCabe, 1 Oct 2011, In : Nature Reviews Endocrinology. 7, 10, p. 563-564 2 p.

Research output: Contribution to journal › Editorial

Proto-oncogene PBF/PTTG1IP Regulates Thyroid Cell Growth and Represses Radioiodide Treatment

Martin Read, Lewy, G., Jim Fong, Neil Sharma, Seed, R., Vicki Smith, Gentilin, E., Warfield, A., Margaret Eggo, Knauf, JA., Wendy Leadbeater, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Oct 2011, In : Cancer Research. 71, 19, p. 6153-64 12 p.

Research output: Contribution to journal › Article

Iodine status of UK schoolgirls: a cross-sectional survey

Vanderpump, MPJ., Lazarus, JH., Smyth, PP., Laurberg, P., Roger Holder, Kristien Boelaert & Jayne Franklyn, 1 Jun 2011, In : Lancet. 377, 9782, p. 2007-2012 6 p.

Research output: Contribution to journal › Article

Presence of Other Autoimmune Diseases in Subjects with Autoimmune Thyroid Disease Reply

Kristien Boelaert & Jayne Franklyn, 1 Oct 2010, In : The American Journal of Medicine. 123, 10, p. E25-E25

Research output: Contribution to journal › Article

Treatment of Graves' Disease with Antithyroid Drugs: Current Perspectives

Kristien Boelaert, 1 Sep 2010, In : Thyroid. 20, 9, p. 943-946 4 p.

Research output: Contribution to journal › Editorial

Who Should Treat Thyroid Cancer? A UK Surgical Perspective

Neil Sharma, Kristien Boelaert & Watkinson, J., 1 Aug 2010, In : Clinical Oncology. 22, 6, p. 413-418 6 p.

Research output: Contribution to journal › Article

Pituitary Tumor Transforming Gene Binding Factor: A New Gene in Breast Cancer

Rachel Spruce, Martin Read, Vicki Smith, Neil Sharma, Reynolds, G., Laura Buckley, Doig, C., Campbell, MJ., Lewy, G., Margaret Eggo, Laurence Loubiere, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 May 2010, In : Cancer Research. 70, 9, p. 3739-3749 11 p.

Research output: Contribution to journal › Article

Older Subjects with Hyperthyroidism Present with a Paucity of Symptoms and Signs: A Large Cross-Sectional Study

Kristien Boelaert, Barbara Torlinska, Roger Holder & Jayne Franklyn, 14 Apr 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 6, p. 2715-2726 12 p.

Research output: Contribution to journal › Article

Thyroid Gland: Revised Guidelines for the Management of Thyroid Cancer

Kristien Boelaert, 1 Apr 2010, In : Nature Reviews Endocrinology. 6, 4, p. 185-186 2 p.

Research output: Contribution to journal › Editorial

Prevalence and Relative Risk of Other Autoimmune Diseases in Subjects with Autoimmune Thyroid Disease

Kristien Boelaert, Paul Newby, Matthew Simmonds, Roger Holder, Carr-Smith, J., Heward, JM., Manji, N., Allahabadia, A., Armitage, M., Chatterjee, KV., Lazarus, JH., Pearce, SH., Vaidya, B., Stephen Gough & Jayne Franklyn, 1 Feb 2010, In : The American Journal of Medicine. 123, 2, p. 183.e1 1 p.

Research output: Contribution to journal › Article

PUG binding factor - a new gene in breast cancer

Christopher McCabe, Watkins, R. J., Martin Read, Vicki Smith, Lewy, G., Laurence Loubiere, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 2010, In : Endocrine Journal.

Research output: Contribution to journal › Article

A novel mechanism of sodium iodide symporter repression in differentiated thyroid cancer

Vicki Smith, Martin Read, Andrew Turnell, Rachel Spruce, Watkinson, J., Lewy, G., Jim Fong, James, SR., Margaret Eggo, Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 1 Sep 2009, In : Journal of Cell Science. 122, 18, p. 3393-3402 10 p.

Research output: Contribution to journal › Article

The association between serum TSH concentration and thyroid cancer

Kristien Boelaert, 20 Jul 2009, In : Endocrine-related cancer.

Research output: Contribution to journal › Article

Prediction of cure and risk of hypothyroidism in patients receiving 131I for hyperthyroidism.

Kristien Boelaert, Syed, AA., Manji, N., Michael Sheppard, Roger Holder, Stephen Gough & Jayne Franklyn, 1 Jan 2009, In : Clinical Endocrinology. 70, 1, p. 129-38 10 p.

Research output: Contribution to journal › Article

A novel mechansim of thyroid tumourigenesis based on inactivation of p53 by the PTTG-binding factor PBF

Martin Read, Rachel Spruce, Andrew Turnell, Dae Kim, Vicki Smith, Jim Fong, Watkinson, J., Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 12 Apr 2008, In : Cancer Research. 68, p. 1855

Research output: Contribution to journal › Abstract

Separase, securin and Rad21 in neural cell growth

Pemberton, H., Jayne Franklyn, Kristien Boelaert, Shiaoyng Chan, Dae Kim, Kim, C., Cheng, SY., Mark Kilby & Christopher McCabe, 1 Oct 2007, In : Journal of Cellular Physiology. 213, 1, p. 45-53 9 p.

Research output: Contribution to journal › Article

PTTG and PBF repress the human sodium iodide symporter

Kristien Boelaert, Vicki Smith, Stratford, A., Kogai, T., Lesley Tannahill, Watkinson, J., Margaret Eggo, Jayne Franklyn & Christopher McCabe, 5 Feb 2007, In : Oncogene. 26, 30, p. 4344-4356 13 p.

Research output: Contribution to journal › Article

Influences of age, gender, smoking and family history on autoimmune thyroid disease phentotype

Manji, N., Carr-Smith, J., Kristien Boelaert, Allahabadia, A., Armitage, M., Chatterjee, VK., Lazarus, JH., Pearce, SHS., Vaidya, B., Stephen Gough & Jayne Franklyn, 26 Sep 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 12, p. 4873-4880 8 p.

Research output: Contribution to journal › Article

Pituitary tumor transforming gene (PTTG) stimulates thyroid cell proliferation via a VEGF/KDR/ID3 autocrine pathway

Dae Kim, Jayne Franklyn, Kristien Boelaert, Margaret Eggo, Watkinson, J. & Christopher McCabe, 5 Sep 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4603-4611 9 p.

Research output: Contribution to journal › Article

Serum TSH concentration as a novel predictor of malignancy in thyroid nodules investigated by fine needle aspiration

Kristien Boelaert, Horacek, J., Roger Holder, Watkinson, J., Michael Sheppard & Jayne Franklyn, 5 Sep 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4295-4301 7 p.

Research output: Contribution to journal › Article

Lack of association between serum TSH or free T4 and body mass index in euthyroid subjects

Manji, N., Kristien Boelaert, Michael Sheppard, Roger Holder, Stephen Gough & Jayne Franklyn, 1 Feb 2006, In : Clinical Endocrinology. 64, 2, p. 125-128 4 p.

Research output: Contribution to journal › Article