Kristien Boelaert
Publications
- 2019
- Published
A high-throughput yellow fluorescent protein (YFP) cell-based screen identifies autophagy modulators to increase the effectiveness of radioiodine therapy
Martin Read, Brookes, K., Alice Fletcher, Thornton, C., Alshahrani, M., Nieto, H., Khan, R., Webster, J., Haggie, P., Verkman, A., Luke Alderwick, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 Nov 2019, In : Endocrine Abstracts. 65, 1 p., OC4.1.Research output: Contribution to journal › Abstract
- E-pub ahead of print
Targeting novel sodium iodide symporter interactors ADP-ribosylation factor 4 (ARF4) and valosin-containing protein (VCP) enhances radioiodine uptake: Targeting NIS interactors to enhance radioiodine uptake
Alice Fletcher, Martin Read, Thornton, C., Dean Larner, Poole, V., Brookes, K., Hannah Nieto, Alshahrani, M., Thompson, R., Gareth Lavery, Landa, I., Fagin, J. A., Campbell, M. J., Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 31 Oct 2019, In : Cancer Research.Research output: Contribution to journal › Article
- Published
Patients treated for hyperthyroidism are at increased risk of becoming obese: findings from a large prospective secondary care cohort
Barbara Torlinska, Nichols, L., Mohammed, M. A., McCabe, C. & Kristien Boelaert, 15 Oct 2019, In : Thyroid. 29, 10, p. 1380-1389 10 p.Research output: Contribution to journal › Article
- Published
Dimerization of the sodium/iodide symporter
Thompson, R. J., Alice Fletcher, Brookes, K., Nieto, H., Alshahrani, M. M., Jonathan Wolf Mueller, Fine, N. H. F., David Hodson, Kristien Boelaert, Martin Read, Vicki Smith & Christopher McCabe, Oct 2019, In : Thyroid. 29, 10, p. 1485-1498 14 p.Research output: Contribution to journal › Article
- Published
Thyroid replacement therapy, thyroid stimulating hormone levels and long-term health outcomes in patients with hypothyroidism: a longitudinal study
Rasiah Thayakaran, Nicola Adderley, Sainsbury, C., Barbara Torlinska, Kristien Boelaert, Dana Sumilo, Malcolm Price, G Neil Thomas, Toulis, K. & Krishnarajah Nirantharakumar, 3 Sep 2019, In : BMJ. 366, l4892.Research output: Contribution to journal › Article
- Published
Risk of incident circulatory disease in patients treated for differentiated thyroid carcinoma with no history of cardiovascular disease
Toulis, K. A., Viola, D., Gkoutos, G., Keerthy, D., Kristien Boelaert & Krishnarajah Nirantharakumar, 1 Aug 2019, In : Clinical Endocrinology. 91, 2, p. 323-330 8 p.Research output: Contribution to journal › Article
- Published
Antigen-specific immunotherapy with thyrotropin receptor peptides in Graves' hyperthyroidism: a phase I study
Pearce, S. H. S., Dayan, C., Wraith, D. C., Barrell, K., Olive, N., Jansson, L., Walker-Smith, T., Carnegie, C., Martin, K. F., Kristien Boelaert, Gilbert, J., Higham, C. E., Muller, I., Murray, R. D., Perros, P., Razvi, S., Vaidya, B., Wernig, F. & Kahaly, G. J., 17 Jul 2019, In : Thyroid. 29, 7, p. 1003-1011 9 p.Research output: Contribution to journal › Article
- Published
Glucocorticoid induced adrenal insufficiency is common in steroid treated glomerular diseases - proposed strategy for screening and management
Karangizi, A. H. K., Al-Shaghana, M., Logan, S., Criseno, S., Webster, R., Kristien Boelaert, Hewins, P. & Lorraine Harper, 6 May 2019, In : BMC Nephrology. 20, 1, 154.Research output: Contribution to journal › Article
- Published
Levothyroxine in Women with Thyroid Peroxidase Antibodies before Conception
Dhillon-smith, R., Middleton, L., Sunner, K., Cheed, V., Baker, K., Farrell-Carver, S., Bender Atik, R., Agrawal, R., Bhatia, K., Edi-Osagie, E., Ghobara, T., Gupta, P., Jurkovic, D., Khalaf, Y., MacLean, M., McCabe, C., Mulbagal, K., Nunes, N., Overton, C., Quenby, S. & 14 others, , 4 Apr 2019, In : The New England Journal of Medicine. 380, p. 1316-1325Research output: Contribution to journal › Article
- E-pub ahead of print
Knowledge of thyroid eye disease in Graves’ Disease patients with and without orbitopathy
Matthew Edmunds & Kristien Boelaert, 28 Jan 2019, In : Thyroid.Research output: Contribution to journal › Article
- Published
Adjuvant rituximab, a potential treatment for the young patient with Graves' hyperthyroidism (RiGD): study protocol for a single-arm, single-stage, phase II trial
Cole, M., Hynes, A. M., Howel, D., Hall, L., Abinun, M., Allahabadia, A., Barrett, T., Kristien Boelaert, Drake, A. J., Dimitri, P., Kirk, J., Zammitt, N., Pearce, S. & Cheetham, T., 21 Jan 2019, In : BMJ open. 9, 1, 10 p., e024705.Research output: Contribution to journal › Article
- Published
Liothyronine cost and prescriptions in England
Taylor, P. N., Razvi, S., Muller, I., Wass, J., Dayan, C. M., Chatterjee, K. & Kristien Boelaert, 1 Jan 2019, In : The Lancet Diabetes and Endocrinology. 7, 1, p. 11-12 2 p.Research output: Contribution to journal › Letter
- 2018
- Published
Biochemical analysis of radioiodine uptake enhancement in endocrine cancer
Alshahrani, M., Alice Fletcher, Thornton, C., Brookes, K., Hannah Nieto, Thompson, R., Martin Read, Kristien Boelaert, Christopher McCabe & Vicki Smith, 1 Nov 2018, In : Endocrine Abstracts. 59, 1 p., OC2.4.Research output: Contribution to journal › Article
- Published
Oncogenic action of pituitary-tumor transforming gene (PBF) in head and neck cancer is associated with poorer overall survival
Martin Read, Modasia, B., Alice Fletcher, Thompson, R., Brookes, K., Hannah Nieto, Moray Campbell, Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 1 Nov 2018, In : Endocrine Abstracts. 59, 1 p., P119.Research output: Contribution to journal › Abstract
- Published
Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism
Cangul, H., Liao, X., Schoenmakers, E., Kero, J., Barone, S., Srichomkwun, P., Iwayama, H., Serra, E. G., Saglam, H., Eren, E., Tarim, O., Nicholas, A. K., Zvetkova, I., Anderson, C. A., Frankl, F. E. K., Boelaert, K., Ojaniemi, M., Jääskeläinen, J., Patyra, K., Löf, C. & 7 others, , 18 Oct 2018, In : JCI Insight. 3, 20, 11 p., e99631.Research output: Contribution to journal › Abstract
- E-pub ahead of print
PTTG and PBF functionally interact with p53 and predict overall survival in head and neck cancer
Martin Read, Modasia, B., Alice Fletcher, Thompson, R., Brookes, K., Peter Rae, Hannah Nieto, Poole, V., Sally Roberts, Moray Campbell, Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 28 Aug 2018, In : Cancer Research. 25 p.Research output: Contribution to journal › Article
- Published
PO-124 PTTG and PBF functionally interact with P53 and predict overall survival in head and neck cancer
Martin Read, Modasia, B., Alice Fletcher, Thompson, R., Baker, K., Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 1 Jul 2018, In : ESMO Open. 3, Suppl. 2, p. A69-A69 1 p.Research output: Contribution to journal › Abstract
- Published
Yellow fluorescent protein (YFP) as a biosensor for intracellular iodide in thyroid cancer cells
Martin Read, Baker, K., Thornton, C., Alshahrani, M., Alice Fletcher, Thompson, R., Haggie, P., Verkman, A., Kristien Boelaert, Vicki Smith & Christopher McCabe, 15 May 2018.Research output: Contribution to conference (unpublished) › Abstract
- Published
The Clinical Utility of Cell-Free DNA Measurement in Differentiated Thyroid Cancer: A Systematic Review
Fussey, J. M., Jennifer Bryant, Nikos Batis, Rachel Spruce, Hartley, A., Good, J. S., Christopher McCabe, Kristien Boelaert, Neil Sharma & Hisham Mehanna, 30 Apr 2018, In : Frontiers in Oncology. 8, APR, 132.Research output: Contribution to journal › Article
- Published
Iodine Status during Pregnancy in a Region of Mild-to-Moderate Iodine Deficiency is not Associated with Adverse Obstetric Outcomes; Results from the Avon Longitudinal Study of Parents and Children (ALSPAC)
Barbara Torlinska, Bath, S. C., Janjua, A., Kristien Boelaert & Chan, S-Y., 1 Mar 2018, In : Nutrients. 10, 3, 291.Research output: Contribution to journal › Article
- 2017
- Published
Functional consequences of the first reported mutations of the proto-oncogene PTTG1IP/PBF
Imruetaicharoenchoke, W., Alice Fletcher, Wenqi Lu, Watkins, RJ., Modasia, B., Poole, V., Hannah Nieto, Thompson, R., Kristien Boelaert, Martin Read, Vicki Smith & Christopher McCabe, Sep 2017, In : Endocrine-related cancer. 24, 9, p. 459-474Research output: Contribution to journal › Article
- Published
MANAGEMENT OF ENDOCRINE DISEASE: Subclinical thyrotoxicosis: prevalence, causes and choice of therapy
Carlé, A., Andersen, S. L., Kristien Boelaert & Laurberg, P., Jun 2017, In : European Journal of Endocrinology. 176, 6, p. R325-R337Research output: Contribution to journal › Review article
- E-pub ahead of print
Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer
Martin Read, Fong, J., Modasia, B., Alice Fletcher, Imruetaicharoenchoke, W., Thompson, R., Hannah Nieto, John Reynolds, Bacon, A., Mallick, U., Hackshaw, A., Watkinson, J., Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 15 May 2017, In : Oncogene. 72326.Research output: Contribution to journal › Article
- Published
Comparative analysis of human and mouse expression data identifies proto-oncogene PTTG- and PBF-associated genes in thyroid cancer
Martin Read, Fong, J., Imruetaicharoenchoke, W., Modasia, B., Hannah Nieto, Alice Fletcher, Thompson, R., Neil Sharma, Watkinson, J., Andrew Turnell, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 Feb 2017, In : Thyroid Research. 10(Suppl 1), 2Research output: Contribution to journal › Abstract
- Published
Controlled Antenatal Thyroid Study: Obstetric Outcomes
Taylor, P., Lacey, A., Thayer, D., Yusof, M., Tabasum, A., Muller, I., Marsh, L., Ludgate, M., Rees, A., Kristien Boelaert, Shiaoyng Chan, Nelson, S., Rees, A., Lazarus, J., Dayan, C., Vaidya, B. & Okosieme, O., 13 Feb 2017, In : Thyroid Research. 10(Suppl 1), 2, p. 2 1 p., O1.Research output: Contribution to journal › Abstract
- Published
Pharmacological enhancement of radioiodine uptake using Src kinase inhibitors
Poole, V., Alice Fletcher, Modasia, B., Neil Sharma, Thompson, R., Imruetaicharoenchoke, W., Martin Read, Kristien Boelaert, Christopher McCabe & Vicki Smith, 13 Feb 2017, In : Thyroid Research. 10(Suppl 1), 2, p. 2 1 p., O2.Research output: Contribution to journal › Abstract
- 2016
- Published
Pro-invasive effect of proto-oncogene PBF is modulated by an interaction with cortactin
Rachel Spruce, Imruetaicharoenchoke, W., Martin Read, Neil Sharma, Poole, V. L., Gentillin, E., Bansal, S., Bosseboeuf, E., Rachel Fletcher, Nieto, H. R., Mallick, U., Hackshaw, A., Hisham Mehanna, Kristien Boelaert, Vicki Smith & Christopher McCabe, Dec 2016, In : The Journal of clinical endocrinology and metabolism. 101, 12, p. 4551-4563Research output: Contribution to journal › Article
- Published
High tumoral expression of PBF and PTTG modulates the DNA damage response and is associated with poor survival in thyroid cancer
Martin Read, Jim Fong, Imruetaicharoenchoke, W., Nieto, H., Modasia, B., Alice Fletcher, Thompson, R., Neil Sharma, Bacon, A., Watkinson, J., Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 4 Nov 2016, In : Endocrine Abstracts. 44, P246.Research output: Contribution to journal › Abstract
- Published
Thyroid stimulating hormone in thyroid cancer: does it matter?
Hannah Nieto & Kristien Boelaert, 1 Nov 2016, In : Endocrine-related cancer. 23, 11, ERC-16-0328.Research output: Contribution to journal › Article
- Published
Multifocality in Sporadic Medullary Thyroid Carcinoma: An International Multicenter Study
Essig, G. F., Porter, K., Schneider, D., Arpaia, D., Lindsey, S. C., Busonero, G., Fineberg, D., Fruci, B., Boelaert, K., Smit, J. W., Meijer, J. A. A., Duntas, L. H., Sharma, N., Costante, G., Filetti, S., Sippel, R. S., Biondi, B., Topliss, D. J., Pacini, F., Maciel, R. M. B. & 2 others, , Nov 2016, In : Thyroid. 26, 11, p. 1563-1572 10 p.Research output: Contribution to journal › Article
- Published
WOMEN IN CANCER PROFILE: From bedside to bench and back: my journey in thyroid disease
Kristien Boelaert, Nov 2016, In : Endocrine-related cancer. 23, 11, p. 9-13Research output: Contribution to journal › Special issue
- Published
Comparative analysis of human and mouse expression data identifies distinct proto-oncogene PBF- and PTTG-associated genes in thyroid cancer
Martin Read, Jim Fong, Imruetaicharoenchoke, W., Modasia, B., Hannah Nieto, Watkinson, J., Kristien Boelaert, Vicki Smith, Andrew Turnell & Christopher McCabe, 1 Jul 2016, In : European Journal of Cancer. 61, Suppl 1, p. S36 1 p., 202.Research output: Contribution to journal › Abstract
- Published
Comparative analysis of human and mouse expression data identifies proto-oncogene PTTG- and PBF-associated genes in thyroid cancer
Martin Read, Fong, J., Imruetaicharoenchoke, W., Modasia, B., Hannah Nieto, Alice Fletcher, Thompson, R., Neil Sharma, Watkinson, J., Andrew Turnell, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 May 2016.Research output: Contribution to conference (unpublished) › Abstract
- Published
The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer
Martin Read, Seed, R. I., Modasia, B., Kwan, P. P. K., Sharma, N., Vicki Smith, Rachel Spruce, Bansal, S., Gagliano, T., Stratford, A. L., Ismail, T., Wakelam, M. J. O., Dae Kim, Stephen Ward, Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Jan 2016, In : Molecular Carcinogenesis. 55, 1, p. 15-26Research output: Contribution to journal › Article
- 2015
- Published
Distinct p53 response profiles in transgenic mouse models of thyroid-specific PBF and PTTG expression
Martin Read, Fong, J., Imruetaicharoenchoke, W., Modasia, B., Lewy, G., Ryan, G., Neil Sharma, Vicki Smith, Watkinson, J., Kristien Boelaert & Christopher McCabe, Nov 2015, In : Endocrine Abstracts. 38, P149.Research output: Contribution to journal › Abstract
- E-pub ahead of print
Effectiveness of metyrapone in treating Cushing's Syndrome: a retrospective multicenter study in 195 patients
Daniel, E., Aylwin, S., Mustafa, O., Ball, S., Munir, A., Boelaert, K., Chortis, V., Cuthbertson, D. J., Daousi, C., Rajeev, S. P., Davis, J., Cheer, K., Drake, W., Gunganah, K., Grossman, A., Gurnell, M., Powlson, A. S., Karavitaki, N., Huguet, I., Kearney, T. & 8 others, , 9 Sep 2015, In : The Journal of clinical endocrinology and metabolism. 100, 11, jc20152616.Research output: Contribution to journal › Article
- Published
Costs and benefits of iodine supplementation for pregnant women in a mildly to moderately iodine-deficient population: a modelling analysis
Mark Monahan, Kristien Boelaert, Kate Jolly, Shiaoyng Chan, Pelham Barton & Tracy Roberts, Sep 2015, In : The Lancet Diabetes and Endocrinology. 3, 9, p. 715-722 8 p.Research output: Contribution to journal › Article
- Published
Management of primary hypothyroidism: statement by the British Thyroid Association Executive Committee
Okosieme, O., Gilbert, J., Abraham, P., Kristien Boelaert, Dayan, C., Gurnell, M., Leese, G., Christopher McCabe, Perros, P., Vicki Smith, Williams, G. & Vanderpump, M., 23 May 2015, In : Clinical Endocrinology.Research output: Contribution to journal › Article
- Published
Clinical challenges of thyroid eye disease in HIV-positive patients on highly active antiretroviral therapy
Matthew Edmunds, Mellington, F., Ford, R. L., Barbara Torlinska, Manavi, K. & Kristien Boelaert, Mar 2015, In : The Journal of clinical endocrinology and metabolism. 100, 3, p. 779-787 9 p.Research output: Contribution to journal › Article
- Published
Miscellaneous Hormones
Vasileios Chortis & Kristien Boelaert, 2015, Side Effects of Drugs. Elsevier, Vol. 37. p. 539-558Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed)
- 2014
- Published
Autoimmune encephalopathy in the context of Graves' disease with ophthalmopathy
Vasileios Chortis, Matthew Edmunds, Littleton, E. T. & Kristien Boelaert, Dec 2014, In : Clinical Endocrinology. 81, 6, p. 936-7 2 p.Research output: Contribution to journal › Article
- Published
One Base Deletion (c.2422delT) in the TPO Gene Causes Severe Congenital Hypothyroidism
Cangul, H., Kristien Boelaert, Timothy Barrett, Dogan, M., Saglam, Y., Kendall, M. & Maher, E., 5 Sep 2014, In : J Clin res Pediatr Endocrinol. 6, 3, p. 169-73Research output: Contribution to journal › Article
- Published
Differences in the recurrence and mortality outcomes rates of incidental and nonincidental papillary thyroid microcarcinoma: a systematic review and meta-analysis of 21 329 person-years of follow-up
Hisham Mehanna, Al-Maqbili, T., Ben Carter, Martin, E., Campain, N., Watkinson, J., McCabe, C., Kristien Boelaert & Jayne Franklyn, Aug 2014, In : The Journal of clinical endocrinology and metabolism. 99, 8, p. 2834-43 10 p.Research output: Contribution to journal › Article
- Published
The PTTG1-binding factor (PBF/PTTG1IP) regulates p53 activity in thyroid cells
Martin Read, Seed, R. I., Jim Fong, Modasia, B., Ryan, G. A., Rachel Spruce, Gagliano, T., Vicki Smith, Stratford, A. L., Kwan, P. K., Neil Sharma, Dixon, O. M., Watkinson, J. C., Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Apr 2014, In : Endocrinology. 155, 4, p. 1222-34 13 p.Research output: Contribution to journal › Article
- Published
Examination of PTTG-Binding Factor (PBF) mRNA reveals functional miRNA target sites and exon-skipping splice variants in thyroid cells
Martin Read, Longman, J., Alice Fletcher, Vicki Smith, Rachel Spruce, Modasia, B., Poole, V., Imruetaicharoenchoke, W., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Mar 2014, In : Endocrine Abstracts. 34, P397.Research output: Contribution to journal › Abstract
- Published
Patient information in Graves' disease and thyroid-associated ophthalmopathy: readability assessment of online resources
Matthew Edmunds, Alastair Denniston, Kristien Boelaert, Jayne Franklyn & Omar Durrani, Jan 2014, In : Thyroid. 24, 1, p. 67-72 6 p.Research output: Contribution to journal › Article
- 2013
- Published
Elevated genetic instability is associated with repressed DNA repair gene expression in a bi-transgenic murine model of PTTG and PBF
Martin Read, Jim Fong, Ryan, G., Vicki Smith, Rachel Spruce, Lewy, G., Watkinson, J., Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 2 Dec 2013.Research output: Contribution to conference (unpublished) › Poster
- Published
Fine needle aspiration and medulla
Essig, G., Porter, K., Schneider, D., Debora, A., Lindsey, S., Busonero, G., Fineberg, D., Fruci, B., Boelaert, K., Smit, J., Meijer, J., Duntas, L., Sharma, N., Costante, G., Filetti, S., Sippel, R., Biondi, B., Topliss, D., Pacini, F., MacIel, R. & 2 others, , 1 Nov 2013, In : Endocrine Practice. 19, 6, p. 920-927 8 p.Research output: Contribution to journal › Article
- Published
Thyroid dyshormonogenesis is mainly caused by TPO mutations in consanguineous community
Cangul, H., Aycan, Z., Olivera-Nappa, A., Saglam, H., Schoenmakers, N. A., Kristien Boelaert, Cetinkaya, S., Tarim, O., Bober, E., Darendeliler, F., Bas, V., Demir, K., Aydin, B. K., Kendall, M., Cole, T., Högler, W., Chatterjee, V. K. K., Timothy Barrett & Eamonn Maher, Aug 2013, In : Clinical Endocrinology. 79, 2, p. 275-81 7 p.Research output: Contribution to journal › Article
- Published
Regulation of Pituitary Tumor Transforming Gene (PTTG) expression and phosphorylation in thyroid cells
Lewy, G. D., Ryan, G. A., Martin Read, Jim Fong, Poole, V., Seed, R. I., Sharma, N., Vicki Smith, Kwan, P. P. K., Stewart, S. L., Bacon, A., Warfield, A., Jayne Franklyn, Christopher McCabe & Kristien Boelaert, 18 Jul 2013, In : Endocrinology.Research output: Contribution to journal › Article
- Published
Manipulation of PBF/PTTG1IP phosphorylation status ; a potential new therapeutic strategy for improving radioiodine uptake in thyroid and other tumors
Vicki Smith, Neil Sharma, Rachel Spruce, Martin Read, Ryan, G., Kwan, P., Ashley Martin, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jul 2013, In : The Journal of clinical endocrinology and metabolism. 98, 7, p. 2876-2886 11 p.Research output: Contribution to journal › Article
- Published
Comparison of mortality in hyperthyroidism during periods of treatment with thionamides and after radioiodine
Kristien Boelaert, Maisonneuve, P., Barbara Torlinska & Jayne Franklyn, May 2013, In : The Journal of clinical endocrinology and metabolism. 98, 5, p. 1869-82 14 p.Research output: Contribution to journal › Article
- Published
Elevated genetic instability is associated with repressed DNA repair gene expression in a bi-transgenic murine model of PTTG and PBF
Martin Read, Jim Fong, Ryan, G., Vicki Smith, Rachel Spruce, Lewy, G., Watkinson, J., Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 2013, p. A24.Research output: Contribution to conference (unpublished) › Abstract
- 2012
- Published
TSHR is the main causative locus in autosomal recessively inherited thyroid dysgenesis
Cangul, H., Aycan, Z., Saglam, H., Forman, J. R., Cetinkaya, S., Tarim, O., Bober, E., Cesur, Y., Kurtoglu, S., Darendeliler, F., Bas, V., Eren, E., Demir, K., Kiraz, A., Aydin, B. K., Karthikeyan, A., Kendall, M., Boelaert, K., Shaw, N. J., Kirk, J. & 3 others, , Jun 2012, In : Journal of pediatric endocrinology & metabolism. 25, 5-6, p. 419-426 8 p.Research output: Contribution to journal › Article
- Published
The pituitary tumor transforming gene in thyroid cancer
Lewy, GD., Neil Sharma, Seed, RI., Vicki Smith, Kristien Boelaert & Christopher McCabe, 5 Apr 2012, In : Journal of endocrinological investigation. 35, 4, p. 425-433Research output: Contribution to journal › Review article
- Published
Dietary factors augment the ability of the proto-oncogene PBF to induce goitrogenesis and hyperplasia in vivo
Martin Read, Vicki Smith, Lewy, G., Ryan, G., Sharma, N., Seed, R., Jim Fong, Kwan, P., Warfield, A., Wendy Leadbeater, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Mar 2012, In : Endocrine Abstracts. 28, OC3.8.Research output: Contribution to journal › Abstract
- Published
Thyrotoxicosis
Jayne Franklyn & Kristien Boelaert, 1 Mar 2012, In : Lancet. 379, 9821, p. 1155-1166 12 p.Research output: Contribution to journal › Article
- Published
PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8
Vicki Smith, Martin Read, Andrew Turnell, Sharma, N., Lewy, G. D., Jim Fong, Seed, R. I., Kwan, P., Ryan, G., Mehanna, H., Shiaoyng Chan, Darras, V. M., Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 2012, In : Endocrinology. 153, 7, p. 3526-36 11 p.Research output: Contribution to journal › Article
- 2011
- Published
Choice of Antithythroid Drugs in Pregnancy Response
Kristien Boelaert, 1 Oct 2011, In : Thyroid. 21, 10, p. 1160-1161 2 p.Research output: Contribution to journal › Article
- Published
Finding the malignant thyroid nodule in the haystack
Kristien Boelaert & Christopher McCabe, 1 Oct 2011, In : Nature Reviews Endocrinology. 7, 10, p. 563-564 2 p.Research output: Contribution to journal › Editorial
- Published
Proto-oncogene PBF/PTTG1IP Regulates Thyroid Cell Growth and Represses Radioiodide Treatment
Martin Read, Lewy, G., Jim Fong, Neil Sharma, Seed, R., Vicki Smith, Gentilin, E., Warfield, A., Margaret Eggo, Knauf, JA., Wendy Leadbeater, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Oct 2011, In : Cancer Research. 71, 19, p. 6153-64 12 p.Research output: Contribution to journal › Article
- Published
Iodine status of UK schoolgirls: a cross-sectional survey
Vanderpump, MPJ., Lazarus, JH., Smyth, PP., Laurberg, P., Roger Holder, Kristien Boelaert & Jayne Franklyn, 1 Jun 2011, In : Lancet. 377, 9782, p. 2007-2012 6 p.Research output: Contribution to journal › Article
- Published
PTTG-Binding Factor (PBF) induces goitrogenesis and represses iodide uptake in vivo
Martin Read, Lewy, G., Neil Sharma, Jim Fong, Vicki Smith, Ryan, GA., Seed, RI., Kwan, PPK., Wendy Leadbeater, Warfield, A., Knauf, JA., Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2011.Research output: Contribution to conference (unpublished) › Paper
- Published
PTTG-Binding Factor (PBF) induces hyperplastic lesions in thyroids of aged mice
Martin Read, Lewy, G., Neil Sharma, Jim Fong, Vicki Smith, Ryan, GA., Seed, RI., Kwan, PPK., Wendy Leadbeater, Warfield, A., Knauf, JA., Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2011.Research output: Contribution to conference (unpublished) › Paper
- 2010
- Published
Presence of Other Autoimmune Diseases in Subjects with Autoimmune Thyroid Disease Reply
Kristien Boelaert & Jayne Franklyn, 1 Oct 2010, In : The American Journal of Medicine. 123, 10, p. E25-E25Research output: Contribution to journal › Article
- Published
The PTTG-Binding Factor (PBF) induces thyroid hyperplastic lesions in aged mice
Martin Read, Lewy, G., Neil Sharma, Jim Fong, Vicki Smith, Seed, RI., Kwan, PPK., Ryan, GA., Wendy Leadbeater, Warfield, A., Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Oct 2010.Research output: Contribution to conference (unpublished) › Abstract
- Published
Thyroid hyperplasia in a transgenic mouse model of PTTG-Binding Factor (PBF) overexpression
Martin Read, Lewy, G., Neil Sharma, Jim Fong, Vicki Smith, Seed, RI., Ryan, GA., Kwan, PP., Wendy Leadbeater, Warfield, A., Margaret Eggo, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Sep 2010.Research output: Contribution to conference (unpublished) › Abstract
- Published
Treatment of Graves' Disease with Antithyroid Drugs: Current Perspectives
Kristien Boelaert, 1 Sep 2010, In : Thyroid. 20, 9, p. 943-946 4 p.Research output: Contribution to journal › Editorial
- Published
Who Should Treat Thyroid Cancer? A UK Surgical Perspective
Neil Sharma, Kristien Boelaert & Watkinson, J., 1 Aug 2010, In : Clinical Oncology. 22, 6, p. 413-418 6 p.Research output: Contribution to journal › Article
- Published
Pituitary Tumor Transforming Gene Binding Factor: A New Gene in Breast Cancer
Rachel Spruce, Martin Read, Vicki Smith, Neil Sharma, Reynolds, G., Laura Buckley, Doig, C., Campbell, MJ., Lewy, G., Margaret Eggo, Laurence Loubiere, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 May 2010, In : Cancer Research. 70, 9, p. 3739-3749 11 p.Research output: Contribution to journal › Article
- Published
Older Subjects with Hyperthyroidism Present with a Paucity of Symptoms and Signs: A Large Cross-Sectional Study
Kristien Boelaert, Barbara Torlinska, Roger Holder & Jayne Franklyn, 14 Apr 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 6, p. 2715-2726 12 p.Research output: Contribution to journal › Article
- Published
Thyroid Gland: Revised Guidelines for the Management of Thyroid Cancer
Kristien Boelaert, 1 Apr 2010, In : Nature Reviews Endocrinology. 6, 4, p. 185-186 2 p.Research output: Contribution to journal › Editorial
- Published
Prevalence and Relative Risk of Other Autoimmune Diseases in Subjects with Autoimmune Thyroid Disease
Kristien Boelaert, Paul Newby, Matthew Simmonds, Roger Holder, Carr-Smith, J., Heward, JM., Manji, N., Allahabadia, A., Armitage, M., Chatterjee, KV., Lazarus, JH., Pearce, SH., Vaidya, B., Stephen Gough & Jayne Franklyn, 1 Feb 2010, In : The American Journal of Medicine. 123, 2, p. 183.e1 1 p.Research output: Contribution to journal › Article
- Published
Akt activation in a murine thyroid goitre model induced by the tumourigenic factor PBF
Martin Read, Lewy, G., Neil Sharma, Jim Fong, Vicki Smith, Seed, RI., Kwan, P., Wendy Leadbeater, Warfield, A., Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2010.Research output: Contribution to conference (unpublished) › Paper
- Published
- 2009
- Published
A novel mechanism of sodium iodide symporter repression in differentiated thyroid cancer
Vicki Smith, Martin Read, Andrew Turnell, Rachel Spruce, Watkinson, J., Lewy, G., Jim Fong, James, SR., Margaret Eggo, Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 1 Sep 2009, In : Journal of Cell Science. 122, 18, p. 3393-3402 10 p.Research output: Contribution to journal › Article
- Published
The association between serum TSH concentration and thyroid cancer
Kristien Boelaert, 20 Jul 2009, In : Endocrine-related cancer.Research output: Contribution to journal › Article
- Published
A role for PTTG binding factor (PBF) in goitrogenesis
Martin Read, Lewy, G., Jim Fong, Vicki Smith, Seed, RI., Watkins, RJ., Warfield, A., Wendy Leadbeater, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2009.Research output: Contribution to conference (unpublished) › Paper
- Published
Enlargement of the thyroid gland in a heterozygous PBF knock-in transgenic mouse model
Martin Read, Jim Fong, Lewy, G., Vicki Smith, Andrew Turnell, Watkins, RJ., Seed, R., Stewart, S., Warfield, A., Wendy Leadbeater, Dae Kim, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2009, p. 371. 1 p.Research output: Contribution to conference (unpublished) › Paper
- Published
Evidence of a role for the PTTG binding protein (PBF) in goitrogenesis
Martin Read, Lewy, G., Jim Fong, Vicki Smith, Seed, RI., Watkins, RJ., Wendy Leadbeater, Watkinson, J., Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2009.Research output: Contribution to conference (unpublished) › Paper
- Published
Prediction of cure and risk of hypothyroidism in patients receiving 131I for hyperthyroidism.
Kristien Boelaert, Syed, AA., Manji, N., Michael Sheppard, Roger Holder, Stephen Gough & Jayne Franklyn, 1 Jan 2009, In : Clinical Endocrinology. 70, 1, p. 129-38 10 p.Research output: Contribution to journal › Article
- 2008
- Published
A novel mechansim of thyroid tumourigenesis based on inactivation of p53 by the PTTG-binding factor PBF
Martin Read, Rachel Spruce, Andrew Turnell, Dae Kim, Vicki Smith, Jim Fong, Watkinson, J., Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 12 Apr 2008, In : Cancer Research. 68, p. 1855Research output: Contribution to journal › Abstract
- 2007
- Published
- Published
PTTG and PBF repress the human sodium iodide symporter
Kristien Boelaert, Vicki Smith, Stratford, A., Kogai, T., Lesley Tannahill, Watkinson, J., Margaret Eggo, Jayne Franklyn & Christopher McCabe, 5 Feb 2007, In : Oncogene. 26, 30, p. 4344-4356 13 p.Research output: Contribution to journal › Article
- Published
Age and gender differences and phenotypes of patients with autoimmune thyroid disease - The UK AITD Consortium
Carr-Smith, J., Manji, N., Kristien Boelaert, Allahabadia, A., Armitage, M., Lazarus, J., Pearce, S., Viadja, B., Stephen Gough & Jayne Franklyn, 1 Jan 2007, p. P877.Research output: Contribution to conference (unpublished) › Abstract
- Published
- Published
The assessment of thyroid neoplasia
Kristien Boelaert, Jayne Franklyn, Michael Sheppard, Hay, I. & Wass, J., 1 Jan 2007, Clinical Endocrine Oncology.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Published
- 2006
- Published
Influences of age, gender, smoking and family history on autoimmune thyroid disease phentotype
Manji, N., Carr-Smith, J., Kristien Boelaert, Allahabadia, A., Armitage, M., Chatterjee, VK., Lazarus, JH., Pearce, SHS., Vaidya, B., Stephen Gough & Jayne Franklyn, 26 Sep 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 12, p. 4873-4880 8 p.Research output: Contribution to journal › Article
- Published
Pituitary tumor transforming gene (PTTG) stimulates thyroid cell proliferation via a VEGF/KDR/ID3 autocrine pathway
Dae Kim, Jayne Franklyn, Kristien Boelaert, Margaret Eggo, Watkinson, J. & Christopher McCabe, 5 Sep 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4603-4611 9 p.Research output: Contribution to journal › Article
- Published
Serum TSH concentration as a novel predictor of malignancy in thyroid nodules investigated by fine needle aspiration
Kristien Boelaert, Horacek, J., Roger Holder, Watkinson, J., Michael Sheppard & Jayne Franklyn, 5 Sep 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4295-4301 7 p.Research output: Contribution to journal › Article
- Published
- Published
Influence of family history on the age of presentation of AITD - the UK AITD consortium
Manji, N., Carr-Smith, J., Kristien Boelaert, Allahabadia, A., Armitage, M., Lazarus, J., Pearce, S., Viadja, B., Stephen Gough & Jayne Franklyn, 1 Jan 2006, p. P878.Research output: Contribution to conference (unpublished) › Abstract
- Published
PTTG binding factor (PBF) can transform cells independently of interaction with PTTG
Stratford, A., Kristien Boelaert, Dae Kim, Jayne Franklyn & Christopher McCabe, 1 Jan 2006, p. P492.Research output: Contribution to conference (unpublished) › Abstract
- Published
- Published
- Published
- Published
- Published
- Published
Repression of the human upsteam enhancer (hNUE) by TTG and PBF
Vicki Smith, Kristien Boelaert, Stratford, A., Sally James, Kogai, T., Jayne Franklyn & Christopher McCabe, 1 Jan 2006, p. P16.Research output: Contribution to conference (unpublished) › Abstract