Kristien Boelaert

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Publications

  1. 2014
  2. Published

    Patient information in Graves' disease and thyroid-associated ophthalmopathy: readability assessment of online resources

    Matthew Edmunds, Alastair Denniston, Kristien Boelaert, Jayne Franklyn & Omar Durrani, Jan 2014, In : Thyroid. 24, 1, p. 67-72 6 p.

    Research output: Contribution to journal › Article

  3. 2013
  4. Published

    Elevated genetic instability is associated with repressed DNA repair gene expression in a bi-transgenic murine model of PTTG and PBF

    Martin Read, Jim Fong, Vicki Smith, Rachel Spruce, Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 2 Dec 2013.

    Research output: Contribution to conference (unpublished) › Poster

  5. Published

    Fine needle aspiration and medulla

    Kristien Boelaert, Neil Sharma & 2 others, , 1 Nov 2013, In : Endocrine Practice. 19, 6, p. 920-927 8 p.

    Research output: Contribution to journal › Article

  6. Published

    Thyroid dyshormonogenesis is mainly caused by TPO mutations in consanguineous community

    Kristien Boelaert, Timothy Barrett & Eamonn Maher, Aug 2013, In : Clinical Endocrinology. 79, 2, p. 275-81 7 p.

    Research output: Contribution to journal › Article

  7. Published

    Regulation of Pituitary Tumor Transforming Gene (PTTG) expression and phosphorylation in thyroid cells

    Martin Read, Jim Fong, Vicki Smith, Jayne Franklyn, Christopher McCabe & Kristien Boelaert, 18 Jul 2013, In : Endocrinology.

    Research output: Contribution to journal › Article

  8. Published

    Manipulation of PBF/PTTG1IP phosphorylation status ; a potential new therapeutic strategy for improving radioiodine uptake in thyroid and other tumors

    Vicki Smith, Neil Sharma, Rachel Spruce, Martin Read, Ashley Martin, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jul 2013, In : The Journal of clinical endocrinology and metabolism. 98, 7, p. 2876-2886 11 p.

    Research output: Contribution to journal › Article

  9. Published

    Comparison of mortality in hyperthyroidism during periods of treatment with thionamides and after radioiodine

    Kristien Boelaert, Barbara Torlinska & Jayne Franklyn, May 2013, In : The Journal of clinical endocrinology and metabolism. 98, 5, p. 1869-82 14 p.

    Research output: Contribution to journal › Article

  10. Published

    Elevated genetic instability is associated with repressed DNA repair gene expression in a bi-transgenic murine model of PTTG and PBF

    Martin Read, Jim Fong, Vicki Smith, Rachel Spruce, Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 2013, p. A24.

    Research output: Contribution to conference (unpublished) › Abstract

  11. 2012
  12. Published

    TSHR is the main causative locus in autosomal recessively inherited thyroid dysgenesis

    Hakan Cangul, Kristien Boelaert & 3 others, , Timothy Barrett & Eamonn Maher, Jun 2012, In : Journal of pediatric endocrinology & metabolism. 25, 5-6, p. 419-426 8 p.

    Research output: Contribution to journal › Article

  13. Published

    The pituitary tumor transforming gene in thyroid cancer

    Neil Sharma, Vicki Smith, Kristien Boelaert & Christopher McCabe, 5 Apr 2012, In : Journal of endocrinological investigation. 35, 4, p. 425-433

    Research output: Contribution to journal › Review article

  14. Published

    Dietary factors augment the ability of the proto-oncogene PBF to induce goitrogenesis and hyperplasia in vivo

    Martin Read, Vicki Smith, Jim Fong, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Mar 2012, In : Endocrine Abstracts. 28, OC3.8.

    Research output: Contribution to journal › Abstract

  15. Published

    Thyrotoxicosis

    Jayne Franklyn & Kristien Boelaert, 1 Mar 2012, In : Lancet. 379, 9821, p. 1155-1166 12 p.

    Research output: Contribution to journal › Article

  16. Published

    PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8

    Vicki Smith, Martin Read, Andrew Turnell, Jim Fong, Shiaoyng Chan, Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 2012, In : Endocrinology. 153, 7, p. 3526-36 11 p.

    Research output: Contribution to journal › Article

  17. 2011
  18. Published

    Choice of Antithythroid Drugs in Pregnancy Response

    Kristien Boelaert, 1 Oct 2011, In : Thyroid. 21, 10, p. 1160-1161 2 p.

    Research output: Contribution to journal › Article

  19. Published

    Finding the malignant thyroid nodule in the haystack

    Kristien Boelaert & Christopher McCabe, 1 Oct 2011, In : Nature Reviews Endocrinology. 7, 10, p. 563-564 2 p.

    Research output: Contribution to journal › Editorial

  20. Published

    Proto-oncogene PBF/PTTG1IP Regulates Thyroid Cell Growth and Represses Radioiodide Treatment

    Martin Read, Jim Fong, Neil Sharma, Vicki Smith, Margaret Eggo, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Oct 2011, In : Cancer Research. 71, 19, p. 6153-64 12 p.

    Research output: Contribution to journal › Article

  21. Published

    Iodine status of UK schoolgirls: a cross-sectional survey

    Roger Holder, Kristien Boelaert & Jayne Franklyn, 1 Jun 2011, In : Lancet. 377, 9782, p. 2007-2012 6 p.

    Research output: Contribution to journal › Article

  22. Published

    PTTG-Binding Factor (PBF) induces goitrogenesis and represses iodide uptake in vivo

    Martin Read, Neil Sharma, Jim Fong, Vicki Smith, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2011.

    Research output: Contribution to conference (unpublished) › Paper

  23. Published

    PTTG-Binding Factor (PBF) induces hyperplastic lesions in thyroids of aged mice

    Martin Read, Neil Sharma, Jim Fong, Vicki Smith, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2011.

    Research output: Contribution to conference (unpublished) › Paper

  24. 2010
  25. Published

    Presence of Other Autoimmune Diseases in Subjects with Autoimmune Thyroid Disease Reply

    Kristien Boelaert & Jayne Franklyn, 1 Oct 2010, In : The American Journal of Medicine. 123, 10, p. E25-E25

    Research output: Contribution to journal › Article

  26. Published

    The PTTG-Binding Factor (PBF) induces thyroid hyperplastic lesions in aged mice

    Martin Read, Neil Sharma, Jim Fong, Vicki Smith, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Oct 2010.

    Research output: Contribution to conference (unpublished) › Abstract

  27. Published

    Thyroid hyperplasia in a transgenic mouse model of PTTG-Binding Factor (PBF) overexpression

    Martin Read, Neil Sharma, Jim Fong, Vicki Smith, Wendy Leadbeater, Margaret Eggo, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Sep 2010.

    Research output: Contribution to conference (unpublished) › Abstract

  28. Published

    Treatment of Graves' Disease with Antithyroid Drugs: Current Perspectives

    Kristien Boelaert, 1 Sep 2010, In : Thyroid. 20, 9, p. 943-946 4 p.

    Research output: Contribution to journal › Editorial

  29. Published

    Who Should Treat Thyroid Cancer? A UK Surgical Perspective

    Neil Sharma, Kristien Boelaert, 1 Aug 2010, In : Clinical Oncology. 22, 6, p. 413-418 6 p.

    Research output: Contribution to journal › Article

  30. Published

    Pituitary Tumor Transforming Gene Binding Factor: A New Gene in Breast Cancer

    Rachel Spruce, Martin Read, Vicki Smith, Neil Sharma, Laura Buckley, Margaret Eggo, Laurence Loubiere, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 May 2010, In : Cancer Research. 70, 9, p. 3739-3749 11 p.

    Research output: Contribution to journal › Article

  31. Published

    Older Subjects with Hyperthyroidism Present with a Paucity of Symptoms and Signs: A Large Cross-Sectional Study

    Kristien Boelaert, Barbara Torlinska, Roger Holder & Jayne Franklyn, 14 Apr 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 6, p. 2715-2726 12 p.

    Research output: Contribution to journal › Article

  32. Published

    Thyroid Gland: Revised Guidelines for the Management of Thyroid Cancer

    Kristien Boelaert, 1 Apr 2010, In : Nature Reviews Endocrinology. 6, 4, p. 185-186 2 p.

    Research output: Contribution to journal › Editorial

  33. Published

    Prevalence and Relative Risk of Other Autoimmune Diseases in Subjects with Autoimmune Thyroid Disease

    Kristien Boelaert, Paul Newby, Matthew Simmonds, Roger Holder, Stephen Gough & Jayne Franklyn, 1 Feb 2010, In : The American Journal of Medicine. 123, 2, p. 183.e1 1 p.

    Research output: Contribution to journal › Article

  34. Published

    Akt activation in a murine thyroid goitre model induced by the tumourigenic factor PBF

    Martin Read, Neil Sharma, Jim Fong, Vicki Smith, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2010.

    Research output: Contribution to conference (unpublished) › Paper

  35. Published

    PUG binding factor - a new gene in breast cancer

    Christopher McCabe, Martin Read, Vicki Smith, Laurence Loubiere, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 2010, In : Endocrine Journal.

    Research output: Contribution to journal › Article

  36. 2009
  37. Published

    A novel mechanism of sodium iodide symporter repression in differentiated thyroid cancer

    Vicki Smith, Martin Read, Andrew Turnell, Rachel Spruce, Jim Fong, Margaret Eggo, Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 1 Sep 2009, In : Journal of Cell Science. 122, 18, p. 3393-3402 10 p.

    Research output: Contribution to journal › Article

  38. Published

    The association between serum TSH concentration and thyroid cancer

    Kristien Boelaert, 20 Jul 2009, In : Endocrine-related cancer.

    Research output: Contribution to journal › Article

  39. Published

    A role for PTTG binding factor (PBF) in goitrogenesis

    Martin Read, Jim Fong, Vicki Smith, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2009.

    Research output: Contribution to conference (unpublished) › Paper

  40. Published

    Enlargement of the thyroid gland in a heterozygous PBF knock-in transgenic mouse model

    Martin Read, Jim Fong, Vicki Smith, Andrew Turnell, Wendy Leadbeater, Dae Kim, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2009, p. 371. 1 p.

    Research output: Contribution to conference (unpublished) › Paper

  41. Published

    Evidence of a role for the PTTG binding protein (PBF) in goitrogenesis

    Martin Read, Jim Fong, Vicki Smith, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2009.

    Research output: Contribution to conference (unpublished) › Paper

  42. Published

    Prediction of cure and risk of hypothyroidism in patients receiving 131I for hyperthyroidism.

    Kristien Boelaert, Michael Sheppard, Roger Holder, Stephen Gough & Jayne Franklyn, 1 Jan 2009, In : Clinical Endocrinology. 70, 1, p. 129-38 10 p.

    Research output: Contribution to journal › Article

  43. 2008
  44. Published

    A novel mechansim of thyroid tumourigenesis based on inactivation of p53 by the PTTG-binding factor PBF

    Martin Read, Rachel Spruce, Andrew Turnell, Dae Kim, Vicki Smith, Jim Fong, Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 12 Apr 2008, In : Cancer Research. 68, p. 1855

    Research output: Contribution to journal › Abstract

  45. 2007
  46. Published

    Separase, securin and Rad21 in neural cell growth

    Jayne Franklyn, Kristien Boelaert, Shiaoyng Chan, Dae Kim, Mark Kilby & Christopher McCabe, 1 Oct 2007, In : Journal of Cellular Physiology. 213, 1, p. 45-53 9 p.

    Research output: Contribution to journal › Article

  47. Published

    PTTG and PBF repress the human sodium iodide symporter

    Kristien Boelaert, Vicki Smith, Lesley Tannahill, Margaret Eggo, Jayne Franklyn & Christopher McCabe, 5 Feb 2007, In : Oncogene. 26, 30, p. 4344-4356 13 p.

    Research output: Contribution to journal › Article

  48. Published

    Age and gender differences and phenotypes of patients with autoimmune thyroid disease - The UK AITD Consortium

    Kristien Boelaert, Stephen Gough & Jayne Franklyn, 1 Jan 2007, p. P877.

    Research output: Contribution to conference (unpublished) › Abstract

  49. Published

    The Sodium Iodide Symporter (NIS) is Repressed by PTTG via the Human NIS Upstream Enhancer (hNUE)

    Vicki Smith, Kristien Boelaert, Sally James, Jayne Franklyn & Christopher McCabe, 1 Jan 2007.

    Research output: Contribution to conference (unpublished) › Abstract

  50. Published

    The assessment of thyroid neoplasia

    Kristien Boelaert, Jayne Franklyn, Michael Sheppard, 1 Jan 2007, Clinical Endocrine Oncology.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  51. Published

    Using an increased fixed dose of 1311 (600MBq) leads to improved outcome in patients with hyperthyroidism

    Kristien Boelaert, Michael Sheppard, Stephen Gough & Jayne Franklyn, 1 Jan 2007, p. P312.

    Research output: Contribution to conference (unpublished) › Abstract

  52. 2006
  53. Published

    Influences of age, gender, smoking and family history on autoimmune thyroid disease phentotype

    Kristien Boelaert, Stephen Gough & Jayne Franklyn, 26 Sep 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 12, p. 4873-4880 8 p.

    Research output: Contribution to journal › Article

  54. Published

    Pituitary tumor transforming gene (PTTG) stimulates thyroid cell proliferation via a VEGF/KDR/ID3 autocrine pathway

    Dae Kim, Jayne Franklyn, Kristien Boelaert, Margaret Eggo & Christopher McCabe, 5 Sep 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4603-4611 9 p.

    Research output: Contribution to journal › Article

  55. Published

    Serum TSH concentration as a novel predictor of malignancy in thyroid nodules investigated by fine needle aspiration

    Kristien Boelaert, Roger Holder, Michael Sheppard & Jayne Franklyn, 5 Sep 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4295-4301 7 p.

    Research output: Contribution to journal › Article

  56. Published

    Lack of association between serum TSH or free T4 and body mass index in euthyroid subjects

    Kristien Boelaert, Michael Sheppard, Roger Holder, Stephen Gough & Jayne Franklyn, 1 Feb 2006, In : Clinical Endocrinology. 64, 2, p. 125-128 4 p.

    Research output: Contribution to journal › Article

  57. Published

    Influence of family history on the age of presentation of AITD - the UK AITD consortium

    Kristien Boelaert, Stephen Gough & Jayne Franklyn, 1 Jan 2006, p. P878.

    Research output: Contribution to conference (unpublished) › Abstract

  58. Published

    PTTG binding factor (PBF) can transform cells independently of interaction with PTTG

    Kristien Boelaert, Dae Kim, Jayne Franklyn & Christopher McCabe, 1 Jan 2006, p. P492.

    Research output: Contribution to conference (unpublished) › Abstract

  59. Published

    Pituitary tumor transforming gene (PTTG) stimulates thyroid cell proliferation via a VEGF/KDR/ID3 autocrine pathway

    Dae Kim, Jayne Franklyn, Kristien Boelaert, Margaret Eggo & Christopher McCabe, 1 Jan 2006, p. P491.

    Research output: Contribution to conference (unpublished) › Abstract

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