Kristien Boelaert

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Publications

  1. 2020
  2. Published

    The prevalence of thyroid dysfunction and autoimmunity in women with history of miscarriage or subfertility

    Rima Smith, Aurelio Tobias Garces, Paul Smith, Lee Middleton, Justin Chu & 14 others, , Mark Kilby, Jane Daniels, Shakila Thangaratinam, Shiaoyng Chan, Kristien Boelaert & Arri Coomarasamy, 1 Aug 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 8, p. 2667–2677

    Research output: Contribution to journal › Article › peer-review

  3. Published

    Drug repurposing identifies inhibitors of the proteostasis network to augment radioiodine uptake in combinatorial approaches targeting thyroid cancer

    Martin Read, Alice Fletcher, Hannah Nieto, Holly Adcock, Liam Cox, Luke Alderwick, Kristien Boelaert, Vicki Smith & Christopher McCabe, 8 May 2020, In: Journal of the Endocrine Society. 4, Issue Supplement 1, 1 p., OR28-03.

    Research output: Contribution to journal › Abstract › peer-review

  4. 2019
  5. Published

    A high-throughput yellow fluorescent protein (YFP) cell-based screen identifies autophagy modulators to increase the effectiveness of radioiodine therapy

    Martin Read, Alice Fletcher, Luke Alderwick, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 Nov 2019, In: Endocrine Abstracts. 65, 1 p., OC4.1.

    Research output: Contribution to journal › Abstract › peer-review

  6. Published

    Levothyroxine to increase live births in euthyroid women with thyroid antibodies trying to conceive: the TABLET RCT

    Lee Middleton, Versha Cheed & 14 others, , Alex Tan, Mark Kilby, Kristien Boelaert, Jane Daniels, Shakila Thangaratinam & Arri Coomarasamy, 31 Oct 2019, In: Efficacy and Mechanism Evaluation. 6, 11, p. 1-102 102 p.

    Research output: Contribution to journal › Article › peer-review

  7. E-pub ahead of print

    Targeting novel sodium iodide symporter interactors ADP-ribosylation factor 4 (ARF4) and valosin-containing protein (VCP) enhances radioiodine uptake: Targeting NIS interactors to enhance radioiodine uptake

    Alice Fletcher, Martin Read, Dean Larner, Hannah Nieto, Gareth Lavery, Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 31 Oct 2019, In: Cancer Research.

    Research output: Contribution to journal › Article › peer-review

  8. Published

    Patients treated for hyperthyroidism are at increased risk of becoming obese: findings from a large prospective secondary care cohort

    Barbara Torlinska, Linda Nichols, Christopher McCabe & Kristien Boelaert, 15 Oct 2019, In: Thyroid. 29, 10, p. 1380-1389 10 p.

    Research output: Contribution to journal › Article › peer-review

  9. Published

    Dimerization of the sodium/iodide symporter

    Alice Fletcher, Jonathan Wolf Mueller, David Hodson, Kristien Boelaert, Martin Read, Vicki Smith & Christopher McCabe, Oct 2019, In: Thyroid. 29, 10, p. 1485-1498 14 p.

    Research output: Contribution to journal › Article › peer-review

  10. Published

    Thyroid replacement therapy, thyroid stimulating hormone concentrations, and long term health outcomes in patients with hypothyroidism: longitudinal study

    Rasiah Thayakaran, Nicola Adderley, Barbara Torlinska, Kristien Boelaert, Dana Sumilo, Malcolm Price, G Neil Thomas & Krishnarajah Nirantharakumar, 3 Sep 2019, In: BMJ. 366, 8 p., l4892.

    Research output: Contribution to journal › Article › peer-review

  11. Published

    Risk of incident circulatory disease in patients treated for differentiated thyroid carcinoma with no history of cardiovascular disease

    Kristien Boelaert & Krishnarajah Nirantharakumar, 1 Aug 2019, In: Clinical Endocrinology. 91, 2, p. 323-330 8 p.

    Research output: Contribution to journal › Article › peer-review

  12. Published

    Antigen-specific immunotherapy with thyrotropin receptor peptides in Graves' hyperthyroidism: a phase I study

    Kristien Boelaert, 17 Jul 2019, In: Thyroid. 29, 7, p. 1003-1011 9 p.

    Research output: Contribution to journal › Article › peer-review

  13. Published

    Glucocorticoid induced adrenal insufficiency is common in steroid treated glomerular diseases - proposed strategy for screening and management

    Kristien Boelaert & Lorraine Harper, 6 May 2019, In: BMC Nephrology. 20, 1, 154.

    Research output: Contribution to journal › Article › peer-review

  14. Published

    Knowledge of thyroid eye disease in Graves’ Disease patients with and without orbitopathy

    Matthew Edmunds & Kristien Boelaert, 9 Apr 2019, In: Thyroid. 29, 4, p. 557-562 6 p.

    Research output: Contribution to journal › Article › peer-review

  15. Published

    Levothyroxine in women with thyroid peroxidase antibodies before conception

    Rima Smith, Lee Middleton, Versha Cheed, Christopher McCabe & 14 others, , Alex Tan, Mark Kilby, Kristien Boelaert, Jane Daniels, Shakila Thangaratinam & Arri Coomarasamy, 4 Apr 2019, In: The New England Journal of Medicine. 380, 14, p. 1316-1325 10 p.

    Research output: Contribution to journal › Article › peer-review

  16. Published

    Adjuvant rituximab, a potential treatment for the young patient with Graves' hyperthyroidism (RiGD): study protocol for a single-arm, single-stage, phase II trial

    Kristien Boelaert, 21 Jan 2019, In: BMJ open. 9, 1, 10 p., e024705.

    Research output: Contribution to journal › Article › peer-review

  17. Published

    Liothyronine cost and prescriptions in England

    Kristien Boelaert, 1 Jan 2019, In: The Lancet Diabetes and Endocrinology. 7, 1, p. 11-12 2 p.

    Research output: Contribution to journal › Letter › peer-review

  18. 2018
  19. Published

    Biochemical analysis of radioiodine uptake enhancement in endocrine cancer

    Alice Fletcher, Hannah Nieto, Martin Read, Kristien Boelaert, Christopher McCabe & Vicki Smith, 1 Nov 2018, In: Endocrine Abstracts. 59, 1 p., OC2.4.

    Research output: Contribution to journal › Article › peer-review

  20. Published

    Oncogenic action of pituitary-tumor transforming gene (PBF) in head and neck cancer is associated with poorer overall survival

    Martin Read, Alice Fletcher, Hannah Nieto, Moray Campbell, Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 1 Nov 2018, In: Endocrine Abstracts. 59, 1 p., P119.

    Research output: Contribution to journal › Abstract › peer-review

  21. Published

    Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism

    Hakan Cangul, Kristien Boelaert & 7 others, , Timothy Barrett, Eamonn Maher, 18 Oct 2018, In: JCI Insight. 3, 20, 11 p., e99631.

    Research output: Contribution to journal › Abstract › peer-review

  22. E-pub ahead of print

    PTTG and PBF functionally interact with p53 and predict overall survival in head and neck cancer

    Martin Read, Alice Fletcher, Peter Rae, Hannah Nieto, Sally Roberts, Moray Campbell, Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 28 Aug 2018, In: Cancer Research. 25 p.

    Research output: Contribution to journal › Article › peer-review

  23. Published

    PO-124 PTTG and PBF functionally interact with P53 and predict overall survival in head and neck cancer

    Martin Read, Alice Fletcher, Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 1 Jul 2018, In: ESMO Open. 3, Suppl. 2, p. A69-A69 1 p.

    Research output: Contribution to journal › Abstract › peer-review

  24. Published

    Yellow fluorescent protein (YFP) as a biosensor for intracellular iodide in thyroid cancer cells

    Martin Read, Alice Fletcher, Kristien Boelaert, Vicki Smith & Christopher McCabe, 15 May 2018.

    Research output: Contribution to conference (unpublished) › Abstract › peer-review

  25. Published

    The Clinical Utility of Cell-Free DNA Measurement in Differentiated Thyroid Cancer: A Systematic Review

    Jennifer Bryant, Nikos Batis, Rachel Spruce, Christopher McCabe, Kristien Boelaert, Neil Sharma & Hisham Mehanna, 30 Apr 2018, In: Frontiers in Oncology. 8, APR, 132.

    Research output: Contribution to journal › Article › peer-review

  26. Published

    The Clinical Utility of Cell-Free DNA Measurement in Differentiated Thyroid Cancer: A Systematic Review.

    Nikos Batis, Rachel Spruce, Anne Hartley, Christopher McCabe, Kristien Boelaert & Hisham Mehanna, 30 Apr 2018, In: Frontiers in Oncology.

    Research output: Contribution to journal › Article › peer-review

  27. Published

    Iodine Status during Pregnancy in a Region of Mild-to-Moderate Iodine Deficiency is not Associated with Adverse Obstetric Outcomes; Results from the Avon Longitudinal Study of Parents and Children (ALSPAC)

    Barbara Torlinska, Kristien Boelaert, 1 Mar 2018, In: Nutrients. 10, 3, 291.

    Research output: Contribution to journal › Article › peer-review

  28. 2017
  29. Published

    Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer

    Martin Read, Alice Fletcher, Hannah Nieto, John Reynolds, Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 14 Sep 2017, In: Oncogene. 36, p. 5296–5308

    Research output: Contribution to journal › Article › peer-review

  30. Published

    Functional consequences of the first reported mutations of the proto-oncogene PTTG1IP/PBF

    Alice Fletcher, Wenqi Lu, Hannah Nieto, Kristien Boelaert, Martin Read, Vicki Smith & Christopher McCabe, Sep 2017, In: Endocrine-related cancer. 24, 9, p. 459-474

    Research output: Contribution to journal › Article › peer-review

  31. Published

    MANAGEMENT OF ENDOCRINE DISEASE: Subclinical thyrotoxicosis: prevalence, causes and choice of therapy

    Kristien Boelaert, Jun 2017, In: European Journal of Endocrinology. 176, 6, p. R325-R337

    Research output: Contribution to journal › Review article › peer-review

  32. Published

    Complex thyroid cancer with likely underlying TSHoma - a medical challenge

    Punith Kempegowda, John Ayuk & Kristien Boelaert, 1 Mar 2017, In: Endocrine Abstracts.

    Research output: Contribution to journal › Article › peer-review

  33. Published

    Comparative analysis of human and mouse expression data identifies proto-oncogene PTTG- and PBF-associated genes in thyroid cancer

    Martin Read, Hannah Nieto, Alice Fletcher, Neil Sharma, Andrew Turnell, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 Feb 2017, In: Thyroid Research. 10(Suppl 1), 2

    Research output: Contribution to journal › Abstract › peer-review

  34. Published

    Controlled Antenatal Thyroid Study: Obstetric Outcomes

    Kristien Boelaert, Shiaoyng Chan, 13 Feb 2017, In: Thyroid Research. 10(Suppl 1), 2, p. 2 1 p., O1.

    Research output: Contribution to journal › Abstract › peer-review

  35. Published

    Pharmacological enhancement of radioiodine uptake using Src kinase inhibitors

    Alice Fletcher, Neil Sharma, Martin Read, Kristien Boelaert, Christopher McCabe & Vicki Smith, 13 Feb 2017, In: Thyroid Research. 10(Suppl 1), 2, p. 2 1 p., O2.

    Research output: Contribution to journal › Abstract › peer-review

  36. 2016
  37. Published

    Pro-invasive effect of proto-oncogene PBF is modulated by an interaction with cortactin

    Rachel Spruce, Martin Read, Neil Sharma, Rachel Fletcher, Hisham Mehanna, Kristien Boelaert, Vicki Smith & Christopher McCabe, Dec 2016, In: The Journal of clinical endocrinology and metabolism. 101, 12, p. 4551-4563

    Research output: Contribution to journal › Article › peer-review

  38. Published

    High tumoral expression of PBF and PTTG modulates the DNA damage response and is associated with poor survival in thyroid cancer

    Martin Read, Jim Fong, Alice Fletcher, Neil Sharma, Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 4 Nov 2016, In: Endocrine Abstracts. 44, P246.

    Research output: Contribution to journal › Abstract › peer-review

  39. Published

    Thyroid stimulating hormone in thyroid cancer: does it matter?

    Hannah Nieto & Kristien Boelaert, 1 Nov 2016, In: Endocrine-related cancer. 23, 11, ERC-16-0328.

    Research output: Contribution to journal › Article › peer-review

  40. Published

    Multifocality in Sporadic Medullary Thyroid Carcinoma: An International Multicenter Study

    Kristien Boelaert, Neil Sharma & 2 others, , Nov 2016, In: Thyroid. 26, 11, p. 1563-1572 10 p.

    Research output: Contribution to journal › Article › peer-review

  41. Published

    WOMEN IN CANCER PROFILE: From bedside to bench and back: my journey in thyroid disease

    Kristien Boelaert, Nov 2016, In: Endocrine-related cancer. 23, 11, p. 9-13

    Research output: Contribution to journal › Special issue › peer-review

  42. Published

    Comparative analysis of human and mouse expression data identifies distinct proto-oncogene PBF- and PTTG-associated genes in thyroid cancer

    Martin Read, Jim Fong, Hannah Nieto, Kristien Boelaert, Vicki Smith, Andrew Turnell & Christopher McCabe, 1 Jul 2016, In: European Journal of Cancer. 61, Suppl 1, p. S36 1 p., 202.

    Research output: Contribution to journal › Abstract › peer-review

  43. Published

    Comparative analysis of human and mouse expression data identifies proto-oncogene PTTG- and PBF-associated genes in thyroid cancer

    Martin Read, Hannah Nieto, Alice Fletcher, Neil Sharma, Andrew Turnell, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 May 2016.

    Research output: Contribution to conference (unpublished) › Abstract › peer-review

  44. Published

    The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer

    Martin Read, Vicki Smith, Rachel Spruce, Dae Kim, Stephen Ward, Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Jan 2016, In: Molecular Carcinogenesis. 55, 1, p. 15-26

    Research output: Contribution to journal › Article › peer-review

  45. 2015
  46. Published

    Distinct p53 response profiles in transgenic mouse models of thyroid-specific PBF and PTTG expression

    Martin Read, Neil Sharma, Vicki Smith, Kristien Boelaert & Christopher McCabe, Nov 2015, In: Endocrine Abstracts. 38, P149.

    Research output: Contribution to journal › Abstract › peer-review

  47. E-pub ahead of print

    Effectiveness of metyrapone in treating Cushing's Syndrome: a retrospective multicenter study in 195 patients

    Kristien Boelaert, Niki Karavitaki & 8 others, , 9 Sep 2015, In: The Journal of clinical endocrinology and metabolism. 100, 11, jc20152616.

    Research output: Contribution to journal › Article › peer-review

  48. Published

    Costs and benefits of iodine supplementation for pregnant women in a mildly to moderately iodine-deficient population: a modelling analysis

    Mark Monahan, Kristien Boelaert, Kate Jolly, Shiaoyng Chan, Pelham Barton & Tracy Roberts, Sep 2015, In: The Lancet Diabetes and Endocrinology. 3, 9, p. 715-722 8 p.

    Research output: Contribution to journal › Article

  49. Published

    Management of primary hypothyroidism: statement by the British Thyroid Association Executive Committee

    Kristien Boelaert, Christopher McCabe, Vicki Smith, 23 May 2015, In: Clinical Endocrinology.

    Research output: Contribution to journal › Article › peer-review

  50. Published

    Clinical challenges of thyroid eye disease in HIV-positive patients on highly active antiretroviral therapy

    Matthew Edmunds, Barbara Torlinska & Kristien Boelaert, Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. 779-787 9 p.

    Research output: Contribution to journal › Article › peer-review

  51. Published

    Miscellaneous Hormones

    Vasileios Chortis & Kristien Boelaert, 2015, Side Effects of Drugs. Elsevier, Vol. 37. p. 539-558

    Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

  52. 2014
  53. Published

    Autoimmune encephalopathy in the context of Graves' disease with ophthalmopathy

    Vasileios Chortis, Matthew Edmunds & Kristien Boelaert, Dec 2014, In: Clinical Endocrinology. 81, 6, p. 936-7 2 p.

    Research output: Contribution to journal › Article › peer-review

  54. Published

    One Base Deletion (c.2422delT) in the TPO Gene Causes Severe Congenital Hypothyroidism

    Kristien Boelaert, Timothy Barrett, 5 Sep 2014, In: J Clin res Pediatr Endocrinol. 6, 3, p. 169-73

    Research output: Contribution to journal › Article › peer-review

  55. Published

    Differences in the recurrence and mortality outcomes rates of incidental and nonincidental papillary thyroid microcarcinoma: a systematic review and meta-analysis of 21 329 person-years of follow-up

    Hisham Mehanna, Ben Carter, Kristien Boelaert & Jayne Franklyn, Aug 2014, In: The Journal of clinical endocrinology and metabolism. 99, 8, p. 2834-43 10 p.

    Research output: Contribution to journal › Article › peer-review

  56. Published

    The PTTG1-binding factor (PBF/PTTG1IP) regulates p53 activity in thyroid cells

    Martin Read, Jim Fong, Rachel Spruce, Vicki Smith, Neil Sharma, Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Apr 2014, In: Endocrinology. 155, 4, p. 1222-34 13 p.

    Research output: Contribution to journal › Article › peer-review

  57. Published

    Examination of PTTG-Binding Factor (PBF) mRNA reveals functional miRNA target sites and exon-skipping splice variants in thyroid cells

    Martin Read, Alice Fletcher, Vicki Smith, Rachel Spruce, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Mar 2014, In: Endocrine Abstracts. 34, P397.

    Research output: Contribution to journal › Abstract › peer-review

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