Kristien Boelaert
Publications
- 2020
- Published
The prevalence of thyroid dysfunction and autoimmunity in women with history of miscarriage or subfertility
Rima Smith, Aurelio Tobias Garces, Paul Smith, Lee Middleton, Justin Chu & 14 others, , 1 Aug 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 8, p. 2667–2677Research output: Contribution to journal › Article › peer-review
- Published
Drug repurposing identifies inhibitors of the proteostasis network to augment radioiodine uptake in combinatorial approaches targeting thyroid cancer
Martin Read, Alice Fletcher, Hannah Nieto, Holly Adcock, Liam Cox, Luke Alderwick, Kristien Boelaert, Vicki Smith & Christopher McCabe, 8 May 2020, In: Journal of the Endocrine Society. 4, Issue Supplement 1, 1 p., OR28-03.Research output: Contribution to journal › Abstract › peer-review
- 2019
- Published
A high-throughput yellow fluorescent protein (YFP) cell-based screen identifies autophagy modulators to increase the effectiveness of radioiodine therapy
Martin Read, Alice Fletcher, Luke Alderwick, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 Nov 2019, In: Endocrine Abstracts. 65, 1 p., OC4.1.Research output: Contribution to journal › Abstract › peer-review
- Published
Levothyroxine to increase live births in euthyroid women with thyroid antibodies trying to conceive: the TABLET RCT
Lee Middleton, Versha Cheed & 14 others, , 31 Oct 2019, In: Efficacy and Mechanism Evaluation. 6, 11, p. 1-102 102 p.Research output: Contribution to journal › Article › peer-review
- E-pub ahead of print
Targeting novel sodium iodide symporter interactors ADP-ribosylation factor 4 (ARF4) and valosin-containing protein (VCP) enhances radioiodine uptake: Targeting NIS interactors to enhance radioiodine uptake
Alice Fletcher, Martin Read, Dean Larner, Hannah Nieto, Gareth Lavery, Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 31 Oct 2019, In: Cancer Research.Research output: Contribution to journal › Article › peer-review
- Published
Patients treated for hyperthyroidism are at increased risk of becoming obese: findings from a large prospective secondary care cohort
Barbara Torlinska, Linda Nichols, Christopher McCabe & Kristien Boelaert, 15 Oct 2019, In: Thyroid. 29, 10, p. 1380-1389 10 p.Research output: Contribution to journal › Article › peer-review
- Published
- Published
Thyroid replacement therapy, thyroid stimulating hormone concentrations, and long term health outcomes in patients with hypothyroidism: longitudinal study
Rasiah Thayakaran, Nicola Adderley, Barbara Torlinska, Kristien Boelaert, Dana Sumilo, Malcolm Price, G Neil Thomas & Krishnarajah Nirantharakumar, 3 Sep 2019, In: BMJ. 366, 8 p., l4892.Research output: Contribution to journal › Article › peer-review
- Published
Risk of incident circulatory disease in patients treated for differentiated thyroid carcinoma with no history of cardiovascular disease
Kristien Boelaert & Krishnarajah Nirantharakumar, 1 Aug 2019, In: Clinical Endocrinology. 91, 2, p. 323-330 8 p.Research output: Contribution to journal › Article › peer-review
- Published
Antigen-specific immunotherapy with thyrotropin receptor peptides in Graves' hyperthyroidism: a phase I study
Kristien Boelaert, 17 Jul 2019, In: Thyroid. 29, 7, p. 1003-1011 9 p.Research output: Contribution to journal › Article › peer-review
- Published
Glucocorticoid induced adrenal insufficiency is common in steroid treated glomerular diseases - proposed strategy for screening and management
Kristien Boelaert & Lorraine Harper, 6 May 2019, In: BMC Nephrology. 20, 1, 154.Research output: Contribution to journal › Article › peer-review
- Published
Knowledge of thyroid eye disease in Graves’ Disease patients with and without orbitopathy
Matthew Edmunds & Kristien Boelaert, 9 Apr 2019, In: Thyroid. 29, 4, p. 557-562 6 p.Research output: Contribution to journal › Article › peer-review
- Published
Levothyroxine in women with thyroid peroxidase antibodies before conception
Rima Smith, Lee Middleton, Versha Cheed, Christopher McCabe & 14 others, , 4 Apr 2019, In: The New England Journal of Medicine. 380, 14, p. 1316-1325 10 p.Research output: Contribution to journal › Article › peer-review
- Published
Adjuvant rituximab, a potential treatment for the young patient with Graves' hyperthyroidism (RiGD): study protocol for a single-arm, single-stage, phase II trial
Kristien Boelaert, 21 Jan 2019, In: BMJ open. 9, 1, 10 p., e024705.Research output: Contribution to journal › Article › peer-review
- Published
Liothyronine cost and prescriptions in England
Kristien Boelaert, 1 Jan 2019, In: The Lancet Diabetes and Endocrinology. 7, 1, p. 11-12 2 p.Research output: Contribution to journal › Letter › peer-review
- 2018
- Published
- Published
Oncogenic action of pituitary-tumor transforming gene (PBF) in head and neck cancer is associated with poorer overall survival
Martin Read, Alice Fletcher, Hannah Nieto, Moray Campbell, Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 1 Nov 2018, In: Endocrine Abstracts. 59, 1 p., P119.Research output: Contribution to journal › Abstract › peer-review
- Published
Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism
Hakan Cangul, Kristien Boelaert & 7 others, , 18 Oct 2018, In: JCI Insight. 3, 20, 11 p., e99631.Research output: Contribution to journal › Abstract › peer-review
- E-pub ahead of print
PTTG and PBF functionally interact with p53 and predict overall survival in head and neck cancer
Martin Read, Alice Fletcher, Peter Rae, Hannah Nieto, Sally Roberts, Moray Campbell, Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 28 Aug 2018, In: Cancer Research. 25 p.Research output: Contribution to journal › Article › peer-review
- Published
PO-124 PTTG and PBF functionally interact with P53 and predict overall survival in head and neck cancer
Martin Read, Alice Fletcher, Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 1 Jul 2018, In: ESMO Open. 3, Suppl. 2, p. A69-A69 1 p.Research output: Contribution to journal › Abstract › peer-review
- Published
- Published
The Clinical Utility of Cell-Free DNA Measurement in Differentiated Thyroid Cancer: A Systematic Review
Jennifer Bryant, Nikos Batis, Rachel Spruce, Christopher McCabe, Kristien Boelaert, Neil Sharma & Hisham Mehanna, 30 Apr 2018, In: Frontiers in Oncology. 8, APR, 132.Research output: Contribution to journal › Article › peer-review
- Published
The Clinical Utility of Cell-Free DNA Measurement in Differentiated Thyroid Cancer: A Systematic Review.
Nikos Batis, Rachel Spruce, Anne Hartley, Christopher McCabe, Kristien Boelaert & Hisham Mehanna, 30 Apr 2018, In: Frontiers in Oncology.Research output: Contribution to journal › Article › peer-review
- Published
Iodine Status during Pregnancy in a Region of Mild-to-Moderate Iodine Deficiency is not Associated with Adverse Obstetric Outcomes; Results from the Avon Longitudinal Study of Parents and Children (ALSPAC)
Barbara Torlinska, Kristien Boelaert, 1 Mar 2018, In: Nutrients. 10, 3, 291.Research output: Contribution to journal › Article › peer-review
- 2017
- Published
Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer
Martin Read, Alice Fletcher, Hannah Nieto, John Reynolds, Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 14 Sep 2017, In: Oncogene. 36, p. 5296–5308Research output: Contribution to journal › Article › peer-review
- Published
Functional consequences of the first reported mutations of the proto-oncogene PTTG1IP/PBF
Alice Fletcher, Wenqi Lu, Hannah Nieto, Kristien Boelaert, Martin Read, Vicki Smith & Christopher McCabe, Sep 2017, In: Endocrine-related cancer. 24, 9, p. 459-474Research output: Contribution to journal › Article › peer-review
- Published
MANAGEMENT OF ENDOCRINE DISEASE: Subclinical thyrotoxicosis: prevalence, causes and choice of therapy
Kristien Boelaert, Jun 2017, In: European Journal of Endocrinology. 176, 6, p. R325-R337Research output: Contribution to journal › Review article › peer-review
- Published
- Published
Comparative analysis of human and mouse expression data identifies proto-oncogene PTTG- and PBF-associated genes in thyroid cancer
Martin Read, Hannah Nieto, Alice Fletcher, Neil Sharma, Andrew Turnell, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 Feb 2017, In: Thyroid Research. 10(Suppl 1), 2Research output: Contribution to journal › Abstract › peer-review
- Published
Controlled Antenatal Thyroid Study: Obstetric Outcomes
Kristien Boelaert, Shiaoyng Chan, 13 Feb 2017, In: Thyroid Research. 10(Suppl 1), 2, p. 2 1 p., O1.Research output: Contribution to journal › Abstract › peer-review
- Published
Pharmacological enhancement of radioiodine uptake using Src kinase inhibitors
Alice Fletcher, Neil Sharma, Martin Read, Kristien Boelaert, Christopher McCabe & Vicki Smith, 13 Feb 2017, In: Thyroid Research. 10(Suppl 1), 2, p. 2 1 p., O2.Research output: Contribution to journal › Abstract › peer-review
- 2016
- Published
Pro-invasive effect of proto-oncogene PBF is modulated by an interaction with cortactin
Rachel Spruce, Martin Read, Neil Sharma, Rachel Fletcher, Hisham Mehanna, Kristien Boelaert, Vicki Smith & Christopher McCabe, Dec 2016, In: The Journal of clinical endocrinology and metabolism. 101, 12, p. 4551-4563Research output: Contribution to journal › Article › peer-review
- Published
High tumoral expression of PBF and PTTG modulates the DNA damage response and is associated with poor survival in thyroid cancer
Martin Read, Jim Fong, Alice Fletcher, Neil Sharma, Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 4 Nov 2016, In: Endocrine Abstracts. 44, P246.Research output: Contribution to journal › Abstract › peer-review
- Published
Thyroid stimulating hormone in thyroid cancer: does it matter?
Hannah Nieto & Kristien Boelaert, 1 Nov 2016, In: Endocrine-related cancer. 23, 11, ERC-16-0328.Research output: Contribution to journal › Article › peer-review
- Published
Multifocality in Sporadic Medullary Thyroid Carcinoma: An International Multicenter Study
Kristien Boelaert, Neil Sharma & 2 others, , Nov 2016, In: Thyroid. 26, 11, p. 1563-1572 10 p.Research output: Contribution to journal › Article › peer-review
- Published
WOMEN IN CANCER PROFILE: From bedside to bench and back: my journey in thyroid disease
Kristien Boelaert, Nov 2016, In: Endocrine-related cancer. 23, 11, p. 9-13Research output: Contribution to journal › Special issue › peer-review
- Published
Comparative analysis of human and mouse expression data identifies distinct proto-oncogene PBF- and PTTG-associated genes in thyroid cancer
Martin Read, Jim Fong, Hannah Nieto, Kristien Boelaert, Vicki Smith, Andrew Turnell & Christopher McCabe, 1 Jul 2016, In: European Journal of Cancer. 61, Suppl 1, p. S36 1 p., 202.Research output: Contribution to journal › Abstract › peer-review
- Published
Comparative analysis of human and mouse expression data identifies proto-oncogene PTTG- and PBF-associated genes in thyroid cancer
Martin Read, Hannah Nieto, Alice Fletcher, Neil Sharma, Andrew Turnell, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 May 2016.Research output: Contribution to conference (unpublished) › Abstract › peer-review
- Published
The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer
Martin Read, Vicki Smith, Rachel Spruce, Dae Kim, Stephen Ward, Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Jan 2016, In: Molecular Carcinogenesis. 55, 1, p. 15-26Research output: Contribution to journal › Article › peer-review
- 2015
- Published
- E-pub ahead of print
Effectiveness of metyrapone in treating Cushing's Syndrome: a retrospective multicenter study in 195 patients
Kristien Boelaert, Niki Karavitaki & 8 others, , 9 Sep 2015, In: The Journal of clinical endocrinology and metabolism. 100, 11, jc20152616.Research output: Contribution to journal › Article › peer-review
- Published
Costs and benefits of iodine supplementation for pregnant women in a mildly to moderately iodine-deficient population: a modelling analysis
Mark Monahan, Kristien Boelaert, Kate Jolly, Shiaoyng Chan, Pelham Barton & Tracy Roberts, Sep 2015, In: The Lancet Diabetes and Endocrinology. 3, 9, p. 715-722 8 p.Research output: Contribution to journal › Article
- Published
- Published
Clinical challenges of thyroid eye disease in HIV-positive patients on highly active antiretroviral therapy
Matthew Edmunds, Barbara Torlinska & Kristien Boelaert, Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. 779-787 9 p.Research output: Contribution to journal › Article › peer-review
- Published
Miscellaneous Hormones
Vasileios Chortis & Kristien Boelaert, 2015, Side Effects of Drugs. Elsevier, Vol. 37. p. 539-558Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
- 2014
- Published
Autoimmune encephalopathy in the context of Graves' disease with ophthalmopathy
Vasileios Chortis, Matthew Edmunds & Kristien Boelaert, Dec 2014, In: Clinical Endocrinology. 81, 6, p. 936-7 2 p.Research output: Contribution to journal › Article › peer-review
- Published
One Base Deletion (c.2422delT) in the TPO Gene Causes Severe Congenital Hypothyroidism
Kristien Boelaert, Timothy Barrett, 5 Sep 2014, In: J Clin res Pediatr Endocrinol. 6, 3, p. 169-73Research output: Contribution to journal › Article › peer-review
- Published
Differences in the recurrence and mortality outcomes rates of incidental and nonincidental papillary thyroid microcarcinoma: a systematic review and meta-analysis of 21 329 person-years of follow-up
Hisham Mehanna, Ben Carter, Kristien Boelaert & Jayne Franklyn, Aug 2014, In: The Journal of clinical endocrinology and metabolism. 99, 8, p. 2834-43 10 p.Research output: Contribution to journal › Article › peer-review
- Published
The PTTG1-binding factor (PBF/PTTG1IP) regulates p53 activity in thyroid cells
Martin Read, Jim Fong, Rachel Spruce, Vicki Smith, Neil Sharma, Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Apr 2014, In: Endocrinology. 155, 4, p. 1222-34 13 p.Research output: Contribution to journal › Article › peer-review
- Published
Examination of PTTG-Binding Factor (PBF) mRNA reveals functional miRNA target sites and exon-skipping splice variants in thyroid cells
Martin Read, Alice Fletcher, Vicki Smith, Rachel Spruce, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Mar 2014, In: Endocrine Abstracts. 34, P397.Research output: Contribution to journal › Abstract › peer-review